COVID-19-Related ARDS: Key Mechanistic Features and Treatments

Name: Work Video:
Duration: 3 min 30 s
John Selickman; Charikleia S. Vrettou; Spyros D. Mentzelopoulos; John J. Marini
{'id': 'https://openalex.org/W4292566848', 'doi': 'https://doi.org/10.3390/jcm11164896', 'title': 'COVID-19-Related ARDS: Key Mechanistic Features and Treatments', 'display_name': 'COVID-19-Related ARDS: Key Mechanistic Features and Treatments', 'publication_year': 2022, 'publication_date': '2022-08-20', 'ids': {'openalex': 'https://openalex.org/W4292566848', 'doi': 'https://doi.org/10.3390/jcm11164896', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/36013135'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/jcm11164896', 'pdf_url': 'https://www.mdpi.com/2077-0383/11/16/4896/pdf?version=1660989784', 'source': {'id': 'https://openalex.org/S2737969411', 'display_name': 'Journal of Clinical Medicine', 'issn_l': '2077-0383', 'issn': ['2077-0383'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/2077-0383/11/16/4896/pdf?version=1660989784', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5079539192', 'display_name': 'John Selickman', 'orcid': 'https://orcid.org/0000-0002-2003-9821'}, 'institutions': [{'id': 'https://openalex.org/I130238516', 'display_name': 'University of Minnesota', 'ror': 'https://ror.org/017zqws13', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130238516']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'John Selickman', 'raw_affiliation_strings': ['Department of Pulmonary and Critical Care Medicine, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pulmonary and Critical Care Medicine, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA', 'institution_ids': ['https://openalex.org/I130238516']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010972418', 'display_name': 'Charikleia S. Vrettou', 'orcid': 'https://orcid.org/0000-0002-1067-8849'}, 'institutions': [{'id': 'https://openalex.org/I200777214', 'display_name': 'National and Kapodistrian University of Athens', 'ror': 'https://ror.org/04gnjpq42', 'country_code': 'GR', 'type': 'education', 'lineage': ['https://openalex.org/I200777214']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Charikleia S. Vrettou', 'raw_affiliation_strings': ['First Department of Intensive Care Medicine, National and Kapodistrian University of Athens Medical School, Evaggelismos General Hospital, 10676 Athens, Greece'], 'affiliations': [{'raw_affiliation_string': 'First Department of Intensive Care Medicine, National and Kapodistrian University of Athens Medical School, Evaggelismos General Hospital, 10676 Athens, Greece', 'institution_ids': ['https://openalex.org/I200777214']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070353875', 'display_name': 'Spyros D. Mentzelopoulos', 'orcid': 'https://orcid.org/0000-0003-1159-8282'}, 'institutions': [{'id': 'https://openalex.org/I200777214', 'display_name': 'National and Kapodistrian University of Athens', 'ror': 'https://ror.org/04gnjpq42', 'country_code': 'GR', 'type': 'education', 'lineage': ['https://openalex.org/I200777214']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Spyros D. Mentzelopoulos', 'raw_affiliation_strings': ['First Department of Intensive Care Medicine, National and Kapodistrian University of Athens Medical School, Evaggelismos General Hospital, 10676 Athens, Greece'], 'affiliations': [{'raw_affiliation_string': 'First Department of Intensive Care Medicine, National and Kapodistrian University of Athens Medical School, Evaggelismos General Hospital, 10676 Athens, Greece', 'institution_ids': ['https://openalex.org/I200777214']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5049611323', 'display_name': 'John J. Marini', 'orcid': 'https://orcid.org/0000-0002-9851-2076'}, 'institutions': [{'id': 'https://openalex.org/I130238516', 'display_name': 'University of Minnesota', 'ror': 'https://ror.org/017zqws13', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130238516']}, {'id': 'https://openalex.org/I1282532422', 'display_name': 'Regions Hospital', 'ror': 'https://ror.org/02bfqd210', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1282532422']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John J. Marini', 'raw_affiliation_strings': ['Department of Pulmonary and Critical Care Medicine, Regions Hospital, St. Paul, MN 55101, USA', 'Department of Pulmonary and Critical Care Medicine, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pulmonary and Critical Care Medicine, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA', 'institution_ids': ['https://openalex.org/I130238516']}, {'raw_affiliation_string': 'Department of Pulmonary and Critical Care Medicine, Regions Hospital, St. Paul, MN 55101, USA', 'institution_ids': ['https://openalex.org/I1282532422']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5079539192'], 'corresponding_institution_ids': ['https://openalex.org/I130238516'], 'apc_list': {'value': 2400, 'currency': 'CHF', 'value_usd': 2598, 'provenance': 'doaj'}, 'apc_paid': {'value': 2400, 'currency': 'CHF', 'value_usd': 2598, 'provenance': 'doaj'}, 'fwci': 1.844, 'has_fulltext': False, 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.999659, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '11', 'issue': '16', 'first_page': '4896', 'last_page': '4896'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10322', 'display_name': 'Respiratory Support and Mechanisms', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10322', 'display_name': 'Respiratory Support and Mechanisms', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10041', 'display_name': 'COVID-19 Clinical Research Studies', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10675', 'display_name': 'Mechanical Circulatory Support Devices', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/diffuse-alveolar-damage', 'display_name': 'Diffuse alveolar damage', 'score': 0.7100347}, {'id': 'https://openalex.org/keywords/chest-radiograph', 'display_name': 'Chest radiograph', 'score': 0.6688682}, {'id': 'https://openalex.org/keywords/atelectasis', 'display_name': 'Atelectasis', 'score': 0.62923586}, {'id': 'https://openalex.org/keywords/pulmonary-compliance', 'display_name': 'Pulmonary compliance', 'score': 0.52913296}, {'id': 'https://openalex.org/keywords/respiratory-physiology', 'display_name': 'Respiratory physiology', 'score': 0.44646716}], 'concepts': [{'id': 'https://openalex.org/C2776348555', 'wikidata': 'https://www.wikidata.org/wiki/Q344873', 'display_name': 'ARDS', 'level': 3, 'score': 0.96971786}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9298606}, {'id': 'https://openalex.org/C9418649', 'wikidata': 'https://www.wikidata.org/wiki/Q5275407', 'display_name': 'Diffuse alveolar damage', 'level': 4, 'score': 0.7100347}, {'id': 'https://openalex.org/C2781137159', 'wikidata': 'https://www.wikidata.org/wiki/Q1283318', 'display_name': 'Chest radiograph', 'level': 3, 'score': 0.6688682}, {'id': 'https://openalex.org/C2776779939', 'wikidata': 'https://www.wikidata.org/wiki/Q1479485', 'display_name': 'Hypoxemia', 'level': 2, 'score': 0.62947834}, {'id': 'https://openalex.org/C2781101014', 'wikidata': 'https://www.wikidata.org/wiki/Q754031', 'display_name': 'Atelectasis', 'level': 3, 'score': 0.62923586}, {'id': 'https://openalex.org/C136936797', 'wikidata': 'https://www.wikidata.org/wiki/Q2990558', 'display_name': 'Pulmonary compliance', 'level': 3, 'score': 0.52913296}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.47534156}, {'id': 'https://openalex.org/C163498912', 'wikidata': 'https://www.wikidata.org/wiki/Q472287', 'display_name': 'Respiratory physiology', 'level': 3, 'score': 0.44646716}, {'id': 'https://openalex.org/C2776468924', 'wikidata': 'https://www.wikidata.org/wiki/Q857667', 'display_name': 'Pulmonary edema', 'level': 3, 'score': 0.43135422}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.42346898}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.38333106}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.37963283}, {'id': 'https://openalex.org/C2909621147', 'wikidata': 'https://www.wikidata.org/wiki/Q344873', 'display_name': 'Acute respiratory distress', 'level': 3, 'score': 0.2842092}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.2239502}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/jcm11164896', 'pdf_url': 'https://www.mdpi.com/2077-0383/11/16/4896/pdf?version=1660989784', 'source': {'id': 'https://openalex.org/S2737969411', 'display_name': 'Journal of Clinical Medicine', 'issn_l': '2077-0383', 'issn': ['2077-0383'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/76025932536749e387174f23467b9ef0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410336', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/36013135', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/jcm11164896', 'pdf_url': 'https://www.mdpi.com/2077-0383/11/16/4896/pdf?version=1660989784', 'source': {'id': 'https://openalex.org/S2737969411', 'display_name': 'Journal of Clinical Medicine', 'issn_l': '2077-0383', 'issn': ['2077-0383'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.84, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 187, 'referenced_works': ['https://openalex.org/W1481799686', 'https://openalex.org/W1525938916', 'https://openalex.org/W1542340631', 'https://openalex.org/W1803784511', 'https://openalex.org/W1924238075', 'https://openalex.org/W1965604728', 'https://openalex.org/W1990202497', 'https://openalex.org/W2006109339', 'https://openalex.org/W2006308571', 'https://openalex.org/W2009069101', 'https://openalex.org/W2009713463', 'https://openalex.org/W2010010248', 'https://openalex.org/W2026521622', 'https://openalex.org/W2032756038', 'https://openalex.org/W2037459166', 'https://openalex.org/W2042273024', 'https://openalex.org/W2046384238', 'https://openalex.org/W2050308681', 'https://openalex.org/W2064838274', 'https://openalex.org/W2068920197', 'https://openalex.org/W2101877480', 'https://openalex.org/W2106923828', 'https://openalex.org/W2121048953', 'https://openalex.org/W2124519382', 'https://openalex.org/W2131228216', 'https://openalex.org/W2132616983', 'https://openalex.org/W2136015910', 'https://openalex.org/W2142441287', 'https://openalex.org/W2147279870', 'https://openalex.org/W2157545462', 'https://openalex.org/W2167743972', 'https://openalex.org/W2171409603', 'https://openalex.org/W2284834937', 'https://openalex.org/W2333922183', 'https://openalex.org/W2337999789', 'https://openalex.org/W2416884408', 'https://openalex.org/W2511618754', 'https://openalex.org/W2597070792', 'https://openalex.org/W2607378823', 'https://openalex.org/W2610582798', 'https://openalex.org/W2620241325', 'https://openalex.org/W2752259597', 'https://openalex.org/W2766417400', 'https://openalex.org/W2795394273', 'https://openalex.org/W2803603947', 'https://openalex.org/W2803978137', 'https://openalex.org/W2889601329', 'https://openalex.org/W2899563816', 'https://openalex.org/W2912354430', 'https://openalex.org/W2938989086', 'https://openalex.org/W2967981766', 'https://openalex.org/W2972443274', 'https://openalex.org/W2973981981', 'https://openalex.org/W2978793344', 'https://openalex.org/W2982576675', 'https://openalex.org/W3004280078', 'https://openalex.org/W3009912996', 'https://openalex.org/W3012627062', 'https://openalex.org/W3012917182', 'https://openalex.org/W3012923578', 'https://openalex.org/W3012955332', 'https://openalex.org/W3013176450', 'https://openalex.org/W3013393665', 'https://openalex.org/W3014294089', 'https://openalex.org/W3016428719', 'https://openalex.org/W3016506145', 'https://openalex.org/W3017125154', 'https://openalex.org/W3017743621', 'https://openalex.org/W3022194827', 'https://openalex.org/W3022564719', 'https://openalex.org/W3025232799', 'https://openalex.org/W3027918021', 'https://openalex.org/W3030748957', 'https://openalex.org/W3032503858', 'https://openalex.org/W3033997257', 'https://openalex.org/W3036110527', 'https://openalex.org/W3036204463', 'https://openalex.org/W3036391214', 'https://openalex.org/W3036512428', 'https://openalex.org/W3036779511', 'https://openalex.org/W3040934200', 'https://openalex.org/W3041319886', 'https://openalex.org/W3042270788', 'https://openalex.org/W3042486011', 'https://openalex.org/W3042555308', 'https://openalex.org/W3043049174', 'https://openalex.org/W3046847474', 'https://openalex.org/W3047144258', 'https://openalex.org/W3049361198', 'https://openalex.org/W3080285565', 'https://openalex.org/W3081027266', 'https://openalex.org/W3082201689', 'https://openalex.org/W3082355253', 'https://openalex.org/W3085029847', 'https://openalex.org/W3087862874', 'https://openalex.org/W3088256443', 'https://openalex.org/W3092594873', 'https://openalex.org/W3092777721', 'https://openalex.org/W3093261446', 'https://openalex.org/W3093604087', 'https://openalex.org/W3093851647', 'https://openalex.org/W3094251384', 'https://openalex.org/W3095682175', 'https://openalex.org/W3095683209', 'https://openalex.org/W3096192847', 'https://openalex.org/W3096704753', 'https://openalex.org/W3100383641', 'https://openalex.org/W3105400342', 'https://openalex.org/W3109926113', 'https://openalex.org/W3110440829', 'https://openalex.org/W3112105690', 'https://openalex.org/W3113196149', 'https://openalex.org/W3121743877', 'https://openalex.org/W3126400175', 'https://openalex.org/W3129583562', 'https://openalex.org/W3131850829', 'https://openalex.org/W3131876040', 'https://openalex.org/W3134724323', 'https://openalex.org/W3140915421', 'https://openalex.org/W3146788278', 'https://openalex.org/W3151199527', 'https://openalex.org/W3154440411', 'https://openalex.org/W3155073785', 'https://openalex.org/W3162905796', 'https://openalex.org/W3163397984', 'https://openalex.org/W3164131743', 'https://openalex.org/W3168339076', 'https://openalex.org/W3168449805', 'https://openalex.org/W3173023460', 'https://openalex.org/W3180282030', 'https://openalex.org/W3181530483', 'https://openalex.org/W3182807823', 'https://openalex.org/W3183454460', 'https://openalex.org/W3189793200', 'https://openalex.org/W3192794601', 'https://openalex.org/W3193375219', 'https://openalex.org/W3196496924', 'https://openalex.org/W3197608731', 'https://openalex.org/W3198241415', 'https://openalex.org/W3198379317', 'https://openalex.org/W3202465431', 'https://openalex.org/W3202915227', 'https://openalex.org/W3205223567', 'https://openalex.org/W3206340696', 'https://openalex.org/W3206922912', 'https://openalex.org/W3207706392', 'https://openalex.org/W3210551809', 'https://openalex.org/W3215922989', 'https://openalex.org/W4200193993', 'https://openalex.org/W4200531577', 'https://openalex.org/W4200571796', 'https://openalex.org/W4205110259', 'https://openalex.org/W4205256292', 'https://openalex.org/W4206443182', 'https://openalex.org/W4207020509', 'https://openalex.org/W4210288619', 'https://openalex.org/W4210343322', 'https://openalex.org/W4210474263', 'https://openalex.org/W4210642183', 'https://openalex.org/W4210812929', 'https://openalex.org/W4210850609', 'https://openalex.org/W4211234516', 'https://openalex.org/W4212891121', 'https://openalex.org/W4214486426', 'https://openalex.org/W4220705942', 'https://openalex.org/W4220849695', 'https://openalex.org/W4221107345', 'https://openalex.org/W4225315608', 'https://openalex.org/W4225326671', 'https://openalex.org/W4225421469', 'https://openalex.org/W4226028230', 'https://openalex.org/W4226055319', 'https://openalex.org/W4226280844', 'https://openalex.org/W4226352404', 'https://openalex.org/W4226497332', 'https://openalex.org/W4229015105', 'https://openalex.org/W4229030713', 'https://openalex.org/W4229078312', 'https://openalex.org/W4231969161', 'https://openalex.org/W4237939525', 'https://openalex.org/W4280635722', 'https://openalex.org/W4281393347', 'https://openalex.org/W4281401987', 'https://openalex.org/W4281673562', 'https://openalex.org/W4281781767', 'https://openalex.org/W4283014710', 'https://openalex.org/W4286630852'], 'related_works': ['https://openalex.org/W4231616230', 'https://openalex.org/W4211138055', 'https://openalex.org/W2430421478', 'https://openalex.org/W2208069632', 'https://openalex.org/W2142830154', 'https://openalex.org/W2109869053', 'https://openalex.org/W2093565141', 'https://openalex.org/W2077559420', 'https://openalex.org/W1999337588', 'https://openalex.org/W1969417991'], 'abstract_inverted_index': {'Acute': [0], 'respiratory': [1, 34, 60, 122], 'distress': [2], 'syndrome': [3, 8, 61], '(ARDS)': [4], 'is': [5, 52, 129], 'a': [6, 37, 53, 73, 105], 'heterogeneous': [7], 'historically': [9], 'characterized': [10], 'by': [11, 57, 92], 'the': [12, 32, 76, 87, 93, 99, 110, 132, 141, 163], 'presence': [13, 94], 'of': [14, 31, 39, 75, 95, 112, 126, 136], 'severe': [15, 58, 84], 'hypoxemia,': [16], 'high-permeability': [17], 'pulmonary': [18, 88, 100], 'edema': [19], 'manifesting': [20], 'as': [21, 36, 72], 'diffuse': [22, 96], 'alveolar': [23], 'infiltrate': [24], 'on': [25, 146], 'chest': [26], 'radiograph,': [27], 'and': [28, 43, 121, 138], 'reduced': [29], 'compliance': [30], 'integrated': [33], 'system': [35], 'result': [38, 74], 'widespread': [40], 'compressive': [41], 'atelectasis': [42], 'fluid-filled': [44], 'alveoli.': [45], 'Coronavirus': [46], 'disease': [47], '19': [48], '(COVID-19)-associated': [49], 'ARDS': [50], '(C-ARDS)': [51], 'novel': [54], 'etiology': [55], 'caused': [56], 'acute': [59], 'coronavirus': [62], '2': [63], '(SARS-CoV-2)': [64], 'that': [65], 'may': [66, 166], 'present': [67], 'with': [68, 152], 'distinct': [69], 'clinical': [70, 106, 160], 'features': [71, 135, 144], 'viral': [77], 'pathobiology': [78], 'unique': [79], 'to': [80, 86, 104, 130, 139, 156], 'SARS-CoV-2.': [81], 'In': [82, 149], 'particular,': [83], 'injury': [85], 'vascular': [89], 'endothelium,': [90], 'accompanied': [91], 'microthrombi': [97], 'in': [98, 108, 162], 'microcirculation,': [101], 'can': [102], 'lead': [103], 'presentation': [107], 'which': [109], 'severity': [111], 'impaired': [113], 'gas': [114], 'exchange': [115], 'becomes': [116], 'uncoupled': [117], 'from': [118, 159], 'lung': [119], 'capacity': [120], 'mechanics.': [123], 'The': [124], 'purpose': [125], 'this': [127], 'review': [128], 'highlight': [131], 'key': [133], 'mechanistic': [134], 'C-ARDS': [137], 'discuss': [140], 'implications': [142], 'these': [143], 'have': [145], 'its': [147], 'treatment.': [148], 'some': [150], 'patients': [151], 'C-ARDS,': [153], 'rigid': [154], 'adherence': [155], 'guidelines': [157], 'derived': [158], 'trials': [161], 'pre-COVID': [164], 'era': [165], 'not': [167], 'be': [168], 'appropriate.': [169]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4292566848', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 3}], 'updated_date': '2024-12-08T15:01:56.301354', 'created_date': '2022-08-22'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
