Abstract: A free open access ebook is available upon publication. Learn more at www.luminosoa.org . Amphibious Subjects is an ethnographic study of a community of self-identified effeminate men—known in local parlance as sasso —residing in coastal Jamestown, a suburb of Accra, Ghana's capital. Drawing on the Ghanaian philosopher Kwame Gyekye's notion of "amphibious personhood," Kwame Edwin Otu argues that sasso embody and articulate amphibious subjectivity in their self-making, creating an identity that moves beyond the homogenizing impulses of western categories of gender and sexuality. Such subjectivity simultaneously unsettles claims purported by the Christian heteronationalist state and LGBT+ human rights organizations that Ghana is predominantly heterosexual or homophobic. Weaving together personal interactions with sasso, participant observation, autoethnography, archival sources, essays from African and African-diasporic literature, and critical analyses of documentaries such as the BBC's The World's Worst Place to Be Gay , Amphibious Subjects is an ethnographic meditation on how Africa is configured as the "heart of homophobic darkness" in transnational LGBT+ human rights imaginaries.