Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4285392207', 'doi': 'https://doi.org/10.3390/diagnostics12071709', 'title': 'Proposal for Practical Approach in Prenatal Diagnosis of Beckwith–Wiedemann Syndrome and Review of the Literature', 'display_name': 'Proposal for Practical Approach in Prenatal Diagnosis of Beckwith–Wiedemann Syndrome and Review of the Literature', 'publication_year': 2022, 'publication_date': '2022-07-13', 'ids': {'openalex': 'https://openalex.org/W4285392207', 'doi': 'https://doi.org/10.3390/diagnostics12071709', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/35885613'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/diagnostics12071709', 'pdf_url': 'https://www.mdpi.com/2075-4418/12/7/1709/pdf?version=1657717586', 'source': {'id': 'https://openalex.org/S4210172076', 'display_name': 'Diagnostics', 'issn_l': '2075-4418', 'issn': ['2075-4418'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/2075-4418/12/7/1709/pdf?version=1657717586', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5045945397', 'display_name': 'Gwo‐Chin Ma', 'orcid': 'https://orcid.org/0000-0002-4925-7101'}, 'institutions': [{'id': 'https://openalex.org/I4210159511', 'display_name': 'Changhua Christian Hospital', 'ror': 'https://ror.org/05d9dtr71', 'country_code': 'TW', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159511']}, {'id': 'https://openalex.org/I882009436', 'display_name': 'Central Taiwan University of Science and Technology', 'ror': 'https://ror.org/03d4d3711', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I882009436']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Gwo-Chin Ma', 'raw_affiliation_strings': ['Department of Genomic Medicine and Center for Medical Genetics, Changhua Christian Hospital, Changhua 50046, Taiwan', 'Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan', 'Research Department, Changhua Christian Hospital, Changhua 50006, Taiwan'], 'affiliations': [{'raw_affiliation_string': 'Department of Genomic Medicine and Center for Medical Genetics, Changhua Christian Hospital, Changhua 50046, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}, {'raw_affiliation_string': 'Research Department, Changhua Christian Hospital, Changhua 50006, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}, {'raw_affiliation_string': 'Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan', 'institution_ids': ['https://openalex.org/I882009436']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005381556', 'display_name': 'Tze-Ho Chen', 'orcid': 'https://orcid.org/0000-0002-8356-4236'}, 'institutions': [{'id': 'https://openalex.org/I4210159511', 'display_name': 'Changhua Christian Hospital', 'ror': 'https://ror.org/05d9dtr71', 'country_code': 'TW', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159511']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Tze-Ho Chen', 'raw_affiliation_strings': ['Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua 50006, Taiwan'], 'affiliations': [{'raw_affiliation_string': 'Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua 50006, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017070297', 'display_name': 'Wan-Ju Wu', 'orcid': 'https://orcid.org/0000-0002-5745-9344'}, 'institutions': [{'id': 'https://openalex.org/I4210159511', 'display_name': 'Changhua Christian Hospital', 'ror': 'https://ror.org/05d9dtr71', 'country_code': 'TW', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159511']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Wan-Ju Wu', 'raw_affiliation_strings': ['Department of Genomic Medicine and Center for Medical Genetics, Changhua Christian Hospital, Changhua 50046, Taiwan', 'Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua 50006, Taiwan'], 'affiliations': [{'raw_affiliation_string': 'Department of Genomic Medicine and Center for Medical Genetics, Changhua Christian Hospital, Changhua 50046, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}, {'raw_affiliation_string': 'Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua 50006, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100436289', 'display_name': 'Dong Soo Lee', 'orcid': 'https://orcid.org/0000-0002-6990-4441'}, 'institutions': [{'id': 'https://openalex.org/I4210159511', 'display_name': 'Changhua Christian Hospital', 'ror': 'https://ror.org/05d9dtr71', 'country_code': 'TW', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159511']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Dong-Jay Lee', 'raw_affiliation_strings': ['Research Department, Changhua Christian Hospital, Changhua 50006, Taiwan'], 'affiliations': [{'raw_affiliation_string': 'Research Department, Changhua Christian Hospital, Changhua 50006, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039279469', 'display_name': 'Wen‐Hsiang Lin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I47396830', 'display_name': 'Bristol-Myers Squibb (Switzerland)', 'ror': 'https://ror.org/02xqc6638', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I4210091812', 'https://openalex.org/I47396830']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Wen-Hsiang Lin', 'raw_affiliation_strings': ['Welgene Biotechnology Company, Nangang Business Park, Taipei 11560, Taiwan'], 'affiliations': [{'raw_affiliation_string': 'Welgene Biotechnology Company, Nangang Business Park, Taipei 11560, Taiwan', 'institution_ids': ['https://openalex.org/I47396830']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100423222', 'display_name': 'Ming Chen', 'orcid': 'https://orcid.org/0000-0001-5076-2917'}, 'institutions': [{'id': 'https://openalex.org/I4210159511', 'display_name': 'Changhua Christian Hospital', 'ror': 'https://ror.org/05d9dtr71', 'country_code': 'TW', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159511']}, {'id': 'https://openalex.org/I4210131804', 'display_name': 'National Taiwan University Hospital', 'ror': 'https://ror.org/03nteze27', 'country_code': 'TW', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210131804']}, {'id': 'https://openalex.org/I16733864', 'display_name': 'National Taiwan University', 'ror': 'https://ror.org/05bqach95', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I16733864']}, {'id': 'https://openalex.org/I25846049', 'display_name': 'National Tsing Hua University', 'ror': 'https://ror.org/00zdnkx70', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I25846049']}, {'id': 'https://openalex.org/I130510345', 'display_name': 'Dayeh University', 'ror': 'https://ror.org/03c6e8r26', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I130510345']}, {'id': 'https://openalex.org/I162838928', 'display_name': 'National Chung Hsing University', 'ror': 'https://ror.org/05vn3ca78', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I162838928']}], 'countries': ['TW'], 'is_corresponding': True, 'raw_author_name': 'Ming Chen', 'raw_affiliation_strings': ['Department of Biomedical Science, Da-Yeh University, Changhua 51591, Taiwan', 'Department of Genomic Medicine and Center for Medical Genetics, Changhua Christian Hospital, Changhua 50046, Taiwan', 'Department of Medical Genetics, National Taiwan University Hospital, Taipei 10041, Taiwan', 'Department of Medical Science, National Tsing Hua University, Hsinchu 30013, Taiwan', 'Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua 50006, Taiwan', 'Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 10041, Taiwan', 'Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 40227, Taiwan', 'Research Department, Changhua Christian Hospital, Changhua 50006, Taiwan'], 'affiliations': [{'raw_affiliation_string': 'Department of Genomic Medicine and Center for Medical Genetics, Changhua Christian Hospital, Changhua 50046, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}, {'raw_affiliation_string': 'Research Department, Changhua Christian Hospital, Changhua 50006, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}, {'raw_affiliation_string': 'Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua 50006, Taiwan', 'institution_ids': ['https://openalex.org/I4210159511']}, {'raw_affiliation_string': 'Department of Medical Genetics, National Taiwan University Hospital, Taipei 10041, Taiwan', 'institution_ids': ['https://openalex.org/I4210131804']}, {'raw_affiliation_string': 'Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 10041, Taiwan', 'institution_ids': ['https://openalex.org/I16733864']}, {'raw_affiliation_string': 'Department of Medical Science, National Tsing Hua University, Hsinchu 30013, Taiwan', 'institution_ids': ['https://openalex.org/I25846049']}, {'raw_affiliation_string': 'Department of Biomedical Science, Da-Yeh University, Changhua 51591, Taiwan', 'institution_ids': ['https://openalex.org/I130510345']}, {'raw_affiliation_string': 'Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 40227, Taiwan', 'institution_ids': ['https://openalex.org/I162838928']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 8, 'corresponding_author_ids': ['https://openalex.org/A5100423222'], 'corresponding_institution_ids': ['https://openalex.org/I4210159511', 'https://openalex.org/I4210131804', 'https://openalex.org/I16733864', 'https://openalex.org/I25846049', 'https://openalex.org/I130510345', 'https://openalex.org/I162838928'], 'apc_list': {'value': 2000, 'currency': 'CHF', 'value_usd': 2165, 'provenance': 'doaj'}, 'apc_paid': {'value': 2000, 'currency': 'CHF', 'value_usd': 2165, 'provenance': 'doaj'}, 'fwci': 0.282, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.522141, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 62, 'max': 72}, 'biblio': {'volume': '12', 'issue': '7', 'first_page': '1709', 'last_page': '1709'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11928', 'display_name': 'Genomic Imprinting and Parental Gene Expression Control', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11928', 'display_name': 'Genomic Imprinting and Parental Gene Expression Control', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10978', 'display_name': 'Prenatal Aneuploidy Diagnosis and Screening Techniques', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetic Modifications and Their Functional Implications', 'score': 0.9775, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/beckwith–wiedemann-syndrome', 'display_name': 'Beckwith–Wiedemann syndrome', 'score': 0.96411014}, {'id': 'https://openalex.org/keywords/prenatal-diagnosis', 'display_name': 'Prenatal Diagnosis', 'score': 0.565799}, {'id': 'https://openalex.org/keywords/fetal-dna-analysis', 'display_name': 'Fetal DNA Analysis', 'score': 0.530648}, {'id': 'https://openalex.org/keywords/imprinting', 'display_name': 'Imprinting (psychology)', 'score': 0.5193428}, {'id': 'https://openalex.org/keywords/preimplantation-genetic-diagnosis', 'display_name': 'Preimplantation Genetic Diagnosis', 'score': 0.515895}, {'id': 'https://openalex.org/keywords/uniparental-disomy', 'display_name': 'Uniparental disomy', 'score': 0.51222914}, {'id': 'https://openalex.org/keywords/genomic-imprinting', 'display_name': 'Genomic imprinting', 'score': 0.50623196}, {'id': 'https://openalex.org/keywords/trisomy-detection', 'display_name': 'Trisomy Detection', 'score': 0.505513}], 'concepts': [{'id': 'https://openalex.org/C2777575177', 'wikidata': 'https://www.wikidata.org/wiki/Q521863', 'display_name': 'Beckwith–Wiedemann syndrome', 'level': 5, 'score': 0.96411014}, {'id': 'https://openalex.org/C2778258057', 'wikidata': 'https://www.wikidata.org/wiki/Q1136569', 'display_name': 'Prenatal diagnosis', 'level': 4, 'score': 0.64704347}, {'id': 'https://openalex.org/C120599132', 'wikidata': 'https://www.wikidata.org/wiki/Q602889', 'display_name': 'Multiplex ligation-dependent probe amplification', 'level': 4, 'score': 0.6261603}, {'id': 'https://openalex.org/C94715292', 'wikidata': 'https://www.wikidata.org/wiki/Q624349', 'display_name': 'Imprinting (psychology)', 'level': 3, 'score': 0.5193428}, {'id': 'https://openalex.org/C2780332060', 'wikidata': 'https://www.wikidata.org/wiki/Q1207929', 'display_name': 'Uniparental disomy', 'level': 5, 'score': 0.51222914}, {'id': 'https://openalex.org/C120821319', 'wikidata': 'https://www.wikidata.org/wiki/Q1501491', 'display_name': 'Copy-number variation', 'level': 4, 'score': 0.50686723}, {'id': 'https://openalex.org/C201492766', 'wikidata': 'https://www.wikidata.org/wiki/Q84087', 'display_name': 'Genomic imprinting', 'level': 5, 'score': 0.50623196}, {'id': 'https://openalex.org/C41091548', 'wikidata': 'https://www.wikidata.org/wiki/Q26939', 'display_name': 'Epigenetics', 'level': 3, 'score': 0.4760204}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.4734409}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.4006614}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39927214}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.36115772}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.34433126}, {'id': 'https://openalex.org/C53226629', 'wikidata': 'https://www.wikidata.org/wiki/Q189967', 'display_name': 'Karyotype', 'level': 4, 'score': 0.3044929}, {'id': 'https://openalex.org/C30481170', 'wikidata': 'https://www.wikidata.org/wiki/Q37748', 'display_name': 'Chromosome', 'level': 3, 'score': 0.28891772}, {'id': 'https://openalex.org/C172680121', 'wikidata': 'https://www.wikidata.org/wiki/Q26513', 'display_name': 'Fetus', 'level': 3, 'score': 0.2834952}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.20299685}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.12120187}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.09210557}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C36823959', 'wikidata': 'https://www.wikidata.org/wiki/Q373027', 'display_name': 'Exon', 'level': 3, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/diagnostics12071709', 'pdf_url': 'https://www.mdpi.com/2075-4418/12/7/1709/pdf?version=1657717586', 'source': {'id': 'https://openalex.org/S4210172076', 'display_name': 'Diagnostics', 'issn_l': '2075-4418', 'issn': ['2075-4418'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/ca6e66eec8c14068a775772eab1b6785', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315620', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/35885613', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/diagnostics12071709', 'pdf_url': 'https://www.mdpi.com/2075-4418/12/7/1709/pdf?version=1657717586', 'source': {'id': 'https://openalex.org/S4210172076', 'display_name': 'Diagnostics', 'issn_l': '2075-4418', 'issn': ['2075-4418'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.56, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 70, 'referenced_works': ['https://openalex.org/W1488234983', 'https://openalex.org/W1527923796', 'https://openalex.org/W1565300788', 'https://openalex.org/W1592374017', 'https://openalex.org/W1638606089', 'https://openalex.org/W1884223264', 'https://openalex.org/W1904933594', 'https://openalex.org/W1972060342', 'https://openalex.org/W1975680353', 'https://openalex.org/W1977274434', 'https://openalex.org/W1978006592', 'https://openalex.org/W1983725267', 'https://openalex.org/W1987255522', 'https://openalex.org/W1989562431', 'https://openalex.org/W1996868983', 'https://openalex.org/W1997527069', 'https://openalex.org/W2003209703', 'https://openalex.org/W2007113715', 'https://openalex.org/W2008897052', 'https://openalex.org/W2012963160', 'https://openalex.org/W2018531315', 'https://openalex.org/W2025842829', 'https://openalex.org/W2026409088', 'https://openalex.org/W2029173029', 'https://openalex.org/W2047830527', 'https://openalex.org/W2049897013', 'https://openalex.org/W2055085859', 'https://openalex.org/W2059592231', 'https://openalex.org/W2060761106', 'https://openalex.org/W2062282470', 'https://openalex.org/W2084610621', 'https://openalex.org/W2084724631', 'https://openalex.org/W2092646864', 'https://openalex.org/W2099548911', 'https://openalex.org/W2105526178', 'https://openalex.org/W2107551567', 'https://openalex.org/W2111768688', 'https://openalex.org/W2114125556', 'https://openalex.org/W2117121254', 'https://openalex.org/W2124293953', 'https://openalex.org/W2133769516', 'https://openalex.org/W2138465841', 'https://openalex.org/W2149307089', 'https://openalex.org/W2152466864', 'https://openalex.org/W2165652435', 'https://openalex.org/W2165984839', 'https://openalex.org/W2168332486', 'https://openalex.org/W2177138952', 'https://openalex.org/W2195975223', 'https://openalex.org/W2464609011', 'https://openalex.org/W2562732901', 'https://openalex.org/W2652018312', 'https://openalex.org/W2777594633', 'https://openalex.org/W2786780539', 'https://openalex.org/W2790819668', 'https://openalex.org/W2810343667', 'https://openalex.org/W2891907375', 'https://openalex.org/W2907760556', 'https://openalex.org/W2918127294', 'https://openalex.org/W2936735202', 'https://openalex.org/W2944515592', 'https://openalex.org/W2985309965', 'https://openalex.org/W3001527192', 'https://openalex.org/W3040552013', 'https://openalex.org/W3096337471', 'https://openalex.org/W3118680921', 'https://openalex.org/W3135364300', 'https://openalex.org/W3161104414', 'https://openalex.org/W3163576420', 'https://openalex.org/W4212911785'], 'related_works': ['https://openalex.org/W4290768982', 'https://openalex.org/W3194946359', 'https://openalex.org/W3158240336', 'https://openalex.org/W2371067942', 'https://openalex.org/W2171322222', 'https://openalex.org/W2141751576', 'https://openalex.org/W2138128786', 'https://openalex.org/W2118587761', 'https://openalex.org/W2080337633', 'https://openalex.org/W2029613472'], 'abstract_inverted_index': {'Beckwith-Wiedemann': [0], 'syndrome': [1], '(BWS)': [2], 'is': [3, 18, 167], 'a': [4, 66], 'phenotypically': [5], 'and': [6, 36, 51, 57, 65, 98, 111, 114, 181], 'genetically': [7], 'heterogeneous': [8], 'disorder': [9], 'associated': [10], 'with': [11, 29, 81], 'epigenetic/genetic': [12], 'aberrations': [13], 'on': [14], 'chromosome': [15, 120], '11p15.4p15.5.': [16], 'There': [17], 'no': [19], 'consensus': [20], 'criterion': [21], 'for': [22, 86, 153], 'prenatal': [23, 33, 70, 82, 154, 193], 'diagnosis': [24, 40, 71, 147, 155], 'of': [25, 38, 48, 60, 72, 77, 119, 156, 188], 'BWS.Three': [26], 'BWS': [27, 62, 73, 79, 157], 'patients': [28], 'their': [30], 'clinical': [31, 189], 'histories,': [32], 'ultrasonographic': [34, 146], 'features,': [35], 'results': [37], 'molecular': [39, 172], 'were': [41, 63, 84, 131], 'presented.': [42], 'Likewise,': [43], 'by': [44, 142, 159], 'incorporating': [45], 'the': [46, 54, 134, 170, 186, 192], 'findings': [47], 'our': [49], 'cases': [50, 80, 190], 'literature': [52], 'review,': [53], 'phenotypic': [55, 136], 'spectrum': [56, 137], 'genotype-phenotype': [58, 129], 'correlations': [59, 130], 'fetal': [61, 89], 'summarized,': [64], 'practical': [67], 'approach': [68], 'in': [69, 106, 191], 'was': [74], 'proposed.A': [75], 'total': [76], '166': [78], 'features': [83, 90, 140], 'included': [85], 'analysis.': [87], 'Common': [88], 'include': [91, 103], 'abdominal': [92], 'wall': [93], 'defects': [94], '(42.8%),': [95], 'polyhydramnios': [96], '(33.1%),': [97], 'macrosomia': [99], '(32.5%).': [100], 'Molecular': [101], 'pathologies': [102], 'methylation': [104, 179], 'changes': [105], 'imprinting': [107], 'control': [108], 'region': [109], '1': [110], '2': [112], '(ICR1': [113], 'ICR2),': [115], 'paternal': [116], 'uniparental': [117], 'disomy': [118], '11p15.5,': [121], 'copy': [122, 182], 'number': [123], 'change': [124], 'involving': [125], '11p15,': [126], 'etc.': [127], 'Some': [128], 'observed.': [132], 'However,': [133], 'broad': [135], 'but': [138], 'limited': [139], 'manifested': [141], 'affected': [143], 'fetuses': [144], 'rendering': [145], 'not': [148], 'easy.Molecular': [149], 'tests': [150], 'are': [151], 'used': [152], 'suspected': [158], 'ultrasonography.': [160], 'Methylation-specific': [161], 'multiplex': [162], 'ligation-dependent': [163], 'probe': [164], 'amplification': [165], '(MS-MLPA)': [166], 'recommended': [168], 'as': [169], 'first-line': [171], 'tool': [173], 'because': [174], 'it': [175], 'simultaneously': [176], 'detects': [177], 'ICR1/ICR2': [178], 'statuses': [180], 'numbers': [183], 'that': [184], 'solve': [185], 'majority': [187], 'scenario.': [194]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4285392207', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}], 'updated_date': '2024-08-31T06:42:02.303347', 'created_date': '2022-07-14'}