Title: Assessment of osteoprotegerin as bone marker in chronic kidney disease patients
Abstract: Chronic kidney disease is a chronic impairment in the structure or function of the kidney. (eg, glomerular filtration rate [GFR] <60 mL/min/1.73 m2 or albuminuria ≥30 mg per 24 hours) for more than 3 months.Renal osteodystrophy is a change in bone morphology in CKD patients, and it is one marker of the skeletal component of the systemic condition of chronic kidney disease mineral bone disease (CKD-MBD) that can be quantified using histomorphometry on bone biopsies chronic kidney disease mineral bone disease (CKD-MBD) defines a complex syndrome of renal osteodystrophy, mineral disorders and cardiovascular disease in patients with chronic kidney disease. The study was a case –control design which conducted in Dialysis Unit in AL-Mahmoodia General Hospital and ALyarmook Teaching Hospital in Baghdad. This study was carried out in private laboratories between September 2021to march 2022. In this investigation,the total subjects were 90, the patient group was Consist of 45 Hemodialysis (HD) (CKD) ( 18 males and 27 females).