Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4282980075', 'doi': 'https://doi.org/10.1158/1538-7445.am2022-1727', 'title': 'Abstract 1727: CD8+ T cells in the invasive margin combined with FOXP3+ T cells in the tumor center significantly associate with survival in resectable gastric cancer, a post-hoc analysis of the Dutch D1/D2 trial', 'display_name': 'Abstract 1727: CD8+ T cells in the invasive margin combined with FOXP3+ T cells in the tumor center significantly associate with survival in resectable gastric cancer, a post-hoc analysis of the Dutch D1/D2 trial', 'publication_year': 2022, 'publication_date': '2022-06-15', 'ids': {'openalex': 'https://openalex.org/W4282980075', 'doi': 'https://doi.org/10.1158/1538-7445.am2022-1727'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2022-1727', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5013607295', 'display_name': 'Tanya T. Soeratram', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Tanya T. Soeratram', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051900899', 'display_name': 'Hedde D. Biesma', 'orcid': 'https://orcid.org/0000-0001-9467-5532'}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Hedde D. Biesma', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006361402', 'display_name': 'Jacqueline M. Egthuijsen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Jacqueline M. Egthuijsen', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048152930', 'display_name': 'Elma Meershoek‐Klein Kranenbarg', 'orcid': 'https://orcid.org/0000-0002-1750-2221'}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Elma Meershoek-Klein Kranenbarg', 'raw_affiliation_strings': ['2Leiden University Medical Center, Leiden, Netherlands.'], 'affiliations': [{'raw_affiliation_string': '2Leiden University Medical Center, Leiden, Netherlands.', 'institution_ids': ['https://openalex.org/I2800006345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110942136', 'display_name': 'Henk H. Hartgrink', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Henk H. Hartgrink', 'raw_affiliation_strings': ['2Leiden University Medical Center, Leiden, Netherlands.'], 'affiliations': [{'raw_affiliation_string': '2Leiden University Medical Center, Leiden, Netherlands.', 'institution_ids': ['https://openalex.org/I2800006345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113786289', 'display_name': 'Cornelis JH van de Velde', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Cornelis J. van de Velde', 'raw_affiliation_strings': ['2Leiden University Medical Center, Leiden, Netherlands.'], 'affiliations': [{'raw_affiliation_string': '2Leiden University Medical Center, Leiden, Netherlands.', 'institution_ids': ['https://openalex.org/I2800006345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020889972', 'display_name': 'Erik van Dijk', 'orcid': 'https://orcid.org/0000-0002-6272-2039'}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Erik van Dijk', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101555341', 'display_name': 'Yongsoo Kim', 'orcid': 'https://orcid.org/0000-0002-2995-2131'}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Yongsoo Kim', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003271927', 'display_name': 'Bauke Ylstra', 'orcid': 'https://orcid.org/0000-0001-9479-3010'}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Bauke Ylstra', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031748554', 'display_name': 'Hanneke W.M. van Laarhoven', 'orcid': 'https://orcid.org/0000-0003-1274-5643'}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Hanneke W. van Laarhoven', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5083943954', 'display_name': 'Nicole C.T. van Grieken', 'orcid': 'https://orcid.org/0000-0001-9992-0760'}, 'institutions': [{'id': 'https://openalex.org/I4210151833', 'display_name': 'Amsterdam University Medical Centers', 'ror': 'https://ror.org/05grdyy37', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Nicole C. van Grieken', 'raw_affiliation_strings': ['1Amsterdam UMC, Amsterdam, Netherlands;'], 'affiliations': [{'raw_affiliation_string': '1Amsterdam UMC, Amsterdam, Netherlands;', 'institution_ids': ['https://openalex.org/I4210151833']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 60}, 'biblio': {'volume': '82', 'issue': '12_Supplement', 'first_page': '1727', 'last_page': '1727'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10696', 'display_name': 'Gastric Cancer Management and Outcomes', 'score': 0.9933, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11067', 'display_name': 'Colorectal Cancer Treatments and Studies', 'score': 0.9786, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cart', 'display_name': 'Cart', 'score': 0.6800431}, {'id': 'https://openalex.org/keywords/tumor-infiltrating-lymphocytes', 'display_name': 'Tumor-infiltrating lymphocytes', 'score': 0.43535757}], 'concepts': [{'id': 'https://openalex.org/C2777275308', 'wikidata': 'https://www.wikidata.org/wiki/Q234668', 'display_name': 'Cart', 'level': 2, 'score': 0.6800431}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6493233}, {'id': 'https://openalex.org/C2779727006', 'wikidata': 'https://www.wikidata.org/wiki/Q426188', 'display_name': 'FOXP3', 'level': 3, 'score': 0.61697054}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.5634769}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.52706194}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.4943061}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.48383084}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.4661414}, {'id': 'https://openalex.org/C2778326572', 'wikidata': 'https://www.wikidata.org/wiki/Q7852668', 'display_name': 'Tumor-infiltrating lymphocytes', 'level': 4, 'score': 0.43535757}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.42379218}, {'id': 'https://openalex.org/C2780380082', 'wikidata': 'https://www.wikidata.org/wiki/Q12646460', 'display_name': 'Granzyme B', 'level': 4, 'score': 0.41269287}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3569097}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.32407975}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.21771735}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2022-1727', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.83}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4244679540', 'https://openalex.org/W4226229889', 'https://openalex.org/W3193909393', 'https://openalex.org/W2974098477', 'https://openalex.org/W2945144341', 'https://openalex.org/W2727188188', 'https://openalex.org/W2618011907', 'https://openalex.org/W2322350723', 'https://openalex.org/W2258783214', 'https://openalex.org/W1597558749'], 'abstract_inverted_index': {'Abstract': [0], 'Introduction:': [1], 'In': [2], 'gastric': [3, 65, 86, 373, 406, 501], 'cancer,': [4, 407, 502], 'studies': [5], 'of': [6, 24, 52, 64, 85, 114, 140, 152, 189, 309, 347, 359, 388, 404, 411, 429, 435, 506, 514], 'tumor': [7, 39, 116, 128, 131, 142, 145, 168, 493], 'infiltrating': [8], 'lymphocytes': [9], 'as': [10, 123, 204, 216, 396], 'a': [11, 47, 62, 312, 363, 427, 503], 'prognostic': [12, 59, 190, 219, 379, 398], 'biomarker': [13, 384], 'show': [14], 'contradictory': [15], 'results.': [16], 'These': [17], 'results': [18], 'may': [19], 'be': [20], 'caused': [21], 'by': [22, 222, 353], 'use': [23], 'variable': [25], 'immunohistochemistry': [26], '(IHC)': [27], 'quantification': [28], 'techniques,': [29], 'different': [30], 'marker': [31], 'selections': [32], 'and': [33, 103, 136, 172, 177, 257, 279, 293, 298, 324, 343, 391, 408, 418], 'particularly': [34], 'inconsistency': [35], 'in': [36, 61, 74, 91, 227, 235, 239, 276, 311, 372, 400, 426, 439, 482, 491, 499], 'the': [37, 75, 115, 127, 141, 193, 228, 240, 285, 348, 401, 483, 492, 507, 515], 'evaluated': [38], 'regions.': [40], 'To': [41], 'overcome': [42], 'these': [43, 440], 'issues,': [44], 'we': [45], 'performed': [46, 107], 'comprehensive': [48], 'digital': [49], 'image': [50], 'analysis': [51, 505], '5': [53, 360], 'immune': [54, 154, 195, 383], 'cell': [55, 196], 'markers': [56, 98, 191], 'for': [57, 96, 162, 295, 300, 382, 518], 'their': [58], 'value': [60], 'cohort': [63], 'cancer': [66, 87, 200, 374], 'patients': [67, 88], 'who': [68], 'were': [69, 89], 'treated': [70], 'with': [71, 199, 246, 254, 263, 289, 487, 497], 'surgery': [72], 'only': [73], 'Dutch': [76, 508], 'D1/D2': [77, 509], 'trial.': [78], 'Methods:': [79], 'All': [80], 'available': [81], 'surgical': [82], 'resection': [83], 'specimens': [84], 'included': [90, 335], 'this': [92], 'study': [93], '(N=251).': [94], 'IHC': [95], 'T-cell': [97, 423], 'CD3,': [99], 'CD45RO,': [100], 'CD8,': [101], 'FOXP3': [102, 223, 392], 'Granzyme': [104], 'B': [105], 'was': [106, 121, 157, 182, 274, 305, 351], 'on': [108], 'serial': [109], 'slides.': [110], 'After': [111], 'manual': [112], 'annotation': [113], 'area,': [117], 'an': [118, 186, 306], 'invasive': [119, 484], 'margin': [120, 485], 'defined': [122], '0.5': [124, 137], 'mm': [125, 138], 'into': [126], 'still': [129], 'containing': [130, 144], 'cells': [132, 146, 155, 481, 490], '(inner': [133], 'margin,': [134, 148], 'IM)': [135], 'outside': [139], 'not': [143], '(outer': [147], 'OM).': [149], 'The': [150, 207, 269, 302, 345, 370, 386], 'density': [151, 197], 'positive': [153], '(cells/mm2)': [156], 'digitally': [158], 'quantified': [159], 'using': [160], 'QuPath': [161], 'each': [163], '0.5x0.5': [164], 'mm2': [165], 'square': [166], 'across': [167], 'center': [169, 494], '(TC),': [170], 'IM': [171], 'OM,': [173], 'separately.': [174], 'A': [175], 'classification': [176], 'regression': [178], 'tree': [179, 210], '(CART)': [180], 'model': [181, 304, 350], 'employed': [183], 'to': [184, 284, 437], 'identify': [185], 'optimal': [187], 'combination': [188, 387], 'from': [192], 'continuous': [194], 'variables': [198], 'specific': [201], 'survival': [202, 498], '(CSS)': [203], 'outcome.': [205], 'Results:': [206], 'CART': [208, 237, 303, 349], 'decision': [209, 241], 'identified': [211, 395], 'CD8': [212, 229, 243, 249, 258, 270, 389], 'OM': [213, 230, 244, 250, 259, 271, 371, 390], '(≥798': [214], 'cells/mm2)': [215, 226], 'most': [217], 'dominant': [218], 'factor,': [220], 'followed': [221], 'TC': [224, 252, 261, 393], '(≥20': [225], 'low': [231, 262], 'subset.': [232], 'This': [233], 'resulted': [234], '3': [236, 327], 'branches': [238, 288], 'tree:': [242], 'high': [245, 253, 272, 422], 'best': [247], 'prognosis,': [248, 256], 'low/FOXP3': [251, 260], 'intermediate': [255], 'worst': [264], 'prognosis': [265, 291], '(Log-rank': [266], 'P-value': [267, 364], '<0.0001).': [268], 'branch': [273, 316, 326], 'enriched': [275], 'EBV+': [277], '(38.2%)': [278], 'MSI-high': [280], '(17.6%)': [281], 'tumors,': [282], 'compared': [283], 'other': [286], 'two': [287], 'poorer': [290], '(4.2%': [292], '3.4%': [294], 'EBV+,': [296], '7.9%': [297], '8.4%': [299], 'MSI-high).': [301], 'independent': [307, 410], 'predictor': [308], 'CSS': [310], 'multivariable': [313], 'cox-regression': [314], '(HR': [315], '2': [317], 'vs': [318, 328], '1:': [319, 329], '4.87,': [320], '95%': [321, 331], 'CI': [322, 332], '1.96-12.07': [323], 'HR': [325], '7.97,': [330], '3.20-19.86),': [333], 'which': [334], 'T': [336, 412, 480, 489], 'stage,': [337, 339, 413, 415], 'N': [338, 414], 'Lauren': [340, 419], 'subtype,': [341], 'EBV-status': [342], 'MSI-status.': [344], 'performance': [346], 'assessed': [352], '5-fold': [354], 'cross-validation,': [355], 'where': [356], '4': [357], 'out': [358], 'models': [361], 'reached': [362], '<': [365], '0.05': [366], '(Likelihood-Ratio': [367], 'test).': [368], 'Conclusions:': [369], 'contains': [375], 'previously': [376], 'overlooked': [377], 'important': [378], 'information': [380], 'valuable': [381], 'studies.': [385], 'is': [394, 409], 'strongest': [397], 'factor': [399], 'risk': [402], 'stratification': [403], 'resectable': [405, 500], 'EBV-status,': [416], 'MSI-status': [417], 'subtype.': [420], 'Moreover,': [421], 'densities': [424], 'found': [425], 'proportion': [428], 'EBV-/MSS': [430], 'tumors': [431], 'support': [432], 'further': [433], 'investigation': [434], 'response': [436], 'immunotherapy': [438], 'subgroups.': [441], 'Citation': [442], 'Format:': [443], 'Tanya': [444], 'T.': [445], 'Soeratram,': [446], 'Hedde': [447], 'D.': [448], 'Biesma,': [449], 'Jacqueline': [450], 'M.': [451], 'Egthuijsen,': [452], 'Elma': [453], 'Meershoek-Klein': [454], 'Kranenbarg,': [455], 'Henk': [456], 'H.': [457], 'Hartgrink,': [458], 'Cornelis': [459], 'J.': [460], 'van': [461, 465, 473, 477], 'de': [462], 'Velde,': [463], 'Erik': [464], 'Dijk,': [466], 'Yongsoo': [467], 'Kim,': [468], 'Bauke': [469], 'Ylstra,': [470], 'Hanneke': [471], 'W.': [472], 'Laarhoven,': [474], 'Nicole': [475], 'C.': [476], 'Grieken.': [478], 'CD8+': [479], 'combined': [486], 'FOXP3+': [488], 'significantly': [495], 'associate': [496], 'post-hoc': [504], 'trial': [510], '[abstract].': [511], 'In:': [512], 'Proceedings': [513], 'American': [516], 'Association': [517], 'Cancer': [519, 530], 'Research': [520], 'Annual': [521], 'Meeting': [522], '2022;': [523], '2022': [524], 'Apr': [525], '8-13.': [526], 'Philadelphia': [527], '(PA):': [528], 'AACR;': [529], 'Res': [531], '2022;82(12_Suppl):Abstract': [532], 'nr': [533], '1727.': [534]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4282980075', 'counts_by_year': [], 'updated_date': '2024-12-15T14:47:25.897935', 'created_date': '2022-06-17'}