Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4282927540', 'doi': 'https://doi.org/10.5146/tjpath.2022.01576', 'title': 'Braf, nras, kit, tert, gnaq/gna11 mutation profile and histomorphological analysis of anorectal melanomas: a clinicopathologic study', 'display_name': 'Braf, nras, kit, tert, gnaq/gna11 mutation profile and histomorphological analysis of anorectal melanomas: a clinicopathologic study', 'publication_year': 2022, 'publication_date': '2022-01-01', 'ids': {'openalex': 'https://openalex.org/W4282927540', 'doi': 'https://doi.org/10.5146/tjpath.2022.01576', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/35642348'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5146/tjpath.2022.01576', 'pdf_url': 'https://www.turkjpath.org/pdf.php3?id=2015', 'source': {'id': 'https://openalex.org/S2738023707', 'display_name': 'Turkish Journal of Pathology', 'issn_l': '1018-5615', 'issn': ['1018-5615', '1309-5730'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310318270', 'host_organization_name': 'Federation of Turkish Pathology Societies', 'host_organization_lineage': ['https://openalex.org/P4310318270'], 'host_organization_lineage_names': ['Federation of Turkish Pathology Societies'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'diamond', 'oa_url': 'https://www.turkjpath.org/pdf.php3?id=2015', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027230770', 'display_name': 'Orhun Çığ Taşkın', 'orcid': 'https://orcid.org/0000-0002-6668-3006'}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Orhun Cig Taskin', 'raw_affiliation_strings': ['ISTANBUL, TURKEY,', 'Istanbul University, Istanbul Faculty of Medicine,'], 'affiliations': [{'raw_affiliation_string': 'Istanbul University, Istanbul Faculty of Medicine,', 'institution_ids': ['https://openalex.org/I67581229']}, {'raw_affiliation_string': 'ISTANBUL, TURKEY,', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102193474', 'display_name': 'Şule Öztürk Sarı', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': True, 'raw_author_name': 'Sule Ozturk Sari', 'raw_affiliation_strings': ['ISTANBUL, TURKEY,', 'Istanbul University, Istanbul Faculty of Medicine,'], 'affiliations': [{'raw_affiliation_string': 'Istanbul University, Istanbul Faculty of Medicine,', 'institution_ids': ['https://openalex.org/I67581229']}, {'raw_affiliation_string': 'ISTANBUL, TURKEY,', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100785720', 'display_name': 'İsmail Yılmaz', 'orcid': 'https://orcid.org/0000-0002-1694-7608'}, 'institutions': [{'id': 'https://openalex.org/I170153556', 'display_name': 'University of Health Science', 'ror': 'https://ror.org/04jpmg381', 'country_code': 'KH', 'type': 'education', 'lineage': ['https://openalex.org/I170153556']}], 'countries': ['KH'], 'is_corresponding': False, 'raw_author_name': 'Ismail Yilmaz', 'raw_affiliation_strings': ['Sultan II. Abdulhamid Han Training and Research Hospital, University of Health Sciences, ISTANBUL, TURKEY'], 'affiliations': [{'raw_affiliation_string': 'Sultan II. Abdulhamid Han Training and Research Hospital, University of Health Sciences, ISTANBUL, TURKEY', 'institution_ids': ['https://openalex.org/I170153556']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073768161', 'display_name': 'Özge Hürdoğan', 'orcid': 'https://orcid.org/0000-0001-8352-8158'}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Ozge Hurdogan', 'raw_affiliation_strings': ['ISTANBUL, TURKEY,', 'Istanbul University, Istanbul Faculty of Medicine,'], 'affiliations': [{'raw_affiliation_string': 'Istanbul University, Istanbul Faculty of Medicine,', 'institution_ids': ['https://openalex.org/I67581229']}, {'raw_affiliation_string': 'ISTANBUL, TURKEY,', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042209368', 'display_name': 'Metin Keskin', 'orcid': 'https://orcid.org/0000-0002-5390-2185'}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Metin Keskin', 'raw_affiliation_strings': ['Department of Surgery, Istanbul University, Istanbul Faculty of Medicine, ISTANBUL, TURKEY'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Istanbul University, Istanbul Faculty of Medicine, ISTANBUL, TURKEY', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040543576', 'display_name': 'Nesimi Büyükbabanı', 'orcid': 'https://orcid.org/0000-0003-0472-4826'}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Nesimi Buyukbabani', 'raw_affiliation_strings': ['ISTANBUL, TURKEY,', 'Istanbul University, Istanbul Faculty of Medicine,'], 'affiliations': [{'raw_affiliation_string': 'Istanbul University, Istanbul Faculty of Medicine,', 'institution_ids': ['https://openalex.org/I67581229']}, {'raw_affiliation_string': 'ISTANBUL, TURKEY,', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5038783528', 'display_name': 'Mine Güllüoğlu', 'orcid': 'https://orcid.org/0000-0002-3967-0779'}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Mine Gulluoglu', 'raw_affiliation_strings': ['ISTANBUL, TURKEY,', 'Istanbul University, Istanbul Faculty of Medicine,'], 'affiliations': [{'raw_affiliation_string': 'ISTANBUL, TURKEY,', 'institution_ids': ['https://openalex.org/I67581229']}, {'raw_affiliation_string': 'Istanbul University, Istanbul Faculty of Medicine,', 'institution_ids': ['https://openalex.org/I67581229']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5102193474'], 'corresponding_institution_ids': ['https://openalex.org/I67581229'], 'apc_list': {'value': 0, 'currency': 'USD', 'value_usd': 0, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.436, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.53252, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 72, 'max': 77}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10392', 'display_name': 'Melanoma', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10392', 'display_name': 'Melanoma', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11533', 'display_name': 'Mammalian MAP Kinase Signaling Pathways', 'score': 0.9782, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunobiology of Dendritic Cells', 'score': 0.9729, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/gnaq', 'display_name': 'GNAQ', 'score': 0.99509215}, {'id': 'https://openalex.org/keywords/braf-gene', 'display_name': 'BRAF gene', 'score': 0.542254}], 'concepts': [{'id': 'https://openalex.org/C2779176653', 'wikidata': 'https://www.wikidata.org/wiki/Q18026236', 'display_name': 'GNAQ', 'level': 4, 'score': 0.99509215}, {'id': 'https://openalex.org/C21790070', 'wikidata': 'https://www.wikidata.org/wiki/Q18030215', 'display_name': 'Neuroblastoma RAS viral oncogene homolog', 'level': 5, 'score': 0.9457128}, {'id': 'https://openalex.org/C36823959', 'wikidata': 'https://www.wikidata.org/wiki/Q373027', 'display_name': 'Exon', 'level': 3, 'score': 0.715659}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.48694527}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.43966842}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.43021095}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.42798427}, {'id': 'https://openalex.org/C2777658100', 'wikidata': 'https://www.wikidata.org/wiki/Q180614', 'display_name': 'Melanoma', 'level': 2, 'score': 0.41784507}, {'id': 'https://openalex.org/C2994225774', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Gene mutation', 'level': 4, 'score': 0.41005546}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.3766059}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.32807267}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.3133424}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3013478}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.28256184}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.17167455}, {'id': 'https://openalex.org/C2781187634', 'wikidata': 'https://www.wikidata.org/wiki/Q20969980', 'display_name': 'KRAS', 'level': 4, 'score': 0.09112057}], 'mesh': [{'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019098', 'descriptor_name': 'Telomerase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004252', 'descriptor_name': 'DNA Mutational Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005091', 'descriptor_name': 'Exons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020558', 'descriptor_name': 'GTP Phosphohydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020558', 'descriptor_name': 'GTP Phosphohydrolases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020558', 'descriptor_name': 'GTP Phosphohydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D044385', 'descriptor_name': 'GTP-Binding Protein alpha Subunits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044385', 'descriptor_name': 'GTP-Binding Protein alpha Subunits', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D044385', 'descriptor_name': 'GTP-Binding Protein alpha Subunits', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D043802', 'descriptor_name': 'GTP-Binding Protein alpha Subunits, Gq-G11', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D043802', 'descriptor_name': 'GTP-Binding Protein alpha Subunits, Gq-G11', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D043802', 'descriptor_name': 'GTP-Binding Protein alpha Subunits, Gq-G11', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048493', 'descriptor_name': 'Proto-Oncogene Proteins B-raf', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048493', 'descriptor_name': 'Proto-Oncogene Proteins B-raf', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019098', 'descriptor_name': 'Telomerase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.5146/tjpath.2022.01576', 'pdf_url': 'https://www.turkjpath.org/pdf.php3?id=2015', 'source': {'id': 'https://openalex.org/S2738023707', 'display_name': 'Turkish Journal of Pathology', 'issn_l': '1018-5615', 'issn': ['1018-5615', '1309-5730'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310318270', 'host_organization_name': 'Federation of Turkish Pathology Societies', 'host_organization_lineage': ['https://openalex.org/P4310318270'], 'host_organization_lineage_names': ['Federation of Turkish Pathology Societies'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518134', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/35642348', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5146/tjpath.2022.01576', 'pdf_url': 'https://www.turkjpath.org/pdf.php3?id=2015', 'source': {'id': 'https://openalex.org/S2738023707', 'display_name': 'Turkish Journal of Pathology', 'issn_l': '1018-5615', 'issn': ['1018-5615', '1309-5730'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310318270', 'host_organization_name': 'Federation of Turkish Pathology Societies', 'host_organization_lineage': ['https://openalex.org/P4310318270'], 'host_organization_lineage_names': ['Federation of Turkish Pathology Societies'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.76}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1522853618', 'https://openalex.org/W1545177819', 'https://openalex.org/W1617666600', 'https://openalex.org/W1939228054', 'https://openalex.org/W1974515789', 'https://openalex.org/W1975401803', 'https://openalex.org/W1977966708', 'https://openalex.org/W1978000550', 'https://openalex.org/W1978086576', 'https://openalex.org/W1982579109', 'https://openalex.org/W2005019494', 'https://openalex.org/W2009599568', 'https://openalex.org/W2009626794', 'https://openalex.org/W2012642290', 'https://openalex.org/W2026446235', 'https://openalex.org/W2039939270', 'https://openalex.org/W2053520756', 'https://openalex.org/W2063384276', 'https://openalex.org/W2063563000', 'https://openalex.org/W2082230082', 'https://openalex.org/W2092097506', 'https://openalex.org/W2096223992', 'https://openalex.org/W2098647445', 'https://openalex.org/W2099200814', 'https://openalex.org/W2103152130', 'https://openalex.org/W2114923812', 'https://openalex.org/W2133079207', 'https://openalex.org/W2147474070', 'https://openalex.org/W2147482894', 'https://openalex.org/W2156266404', 'https://openalex.org/W2157494981', 'https://openalex.org/W2161917991', 'https://openalex.org/W2165516169', 'https://openalex.org/W2166681703', 'https://openalex.org/W2223599197', 'https://openalex.org/W2312500092', 'https://openalex.org/W2315613066', 'https://openalex.org/W2416049642', 'https://openalex.org/W2502134830', 'https://openalex.org/W2514896599', 'https://openalex.org/W2530217932', 'https://openalex.org/W2557541291', 'https://openalex.org/W2570819007', 'https://openalex.org/W2598700460', 'https://openalex.org/W2601908725', 'https://openalex.org/W2623137661', 'https://openalex.org/W2781995165', 'https://openalex.org/W2789663417', 'https://openalex.org/W2800401754', 'https://openalex.org/W2885898493', 'https://openalex.org/W2903205072', 'https://openalex.org/W2913100067', 'https://openalex.org/W2917404286', 'https://openalex.org/W2918525553', 'https://openalex.org/W2960092050', 'https://openalex.org/W2966337348', 'https://openalex.org/W2982435166', 'https://openalex.org/W3196532862', 'https://openalex.org/W4234660273', 'https://openalex.org/W4243765102', 'https://openalex.org/W4299811786'], 'related_works': ['https://openalex.org/W4362495258', 'https://openalex.org/W3046077529', 'https://openalex.org/W2971706352', 'https://openalex.org/W2940291671', 'https://openalex.org/W2784358886', 'https://openalex.org/W2345165199', 'https://openalex.org/W2146772089', 'https://openalex.org/W2141202463', 'https://openalex.org/W2114923812', 'https://openalex.org/W2025287590'], 'abstract_inverted_index': {'Primary': [0], 'anorectal': [1], 'melanomas': [2], '(AMs)': [3], 'are': [4, 17, 206, 232], 'uncommon': [5, 207], 'neoplasms': [6], 'with': [7, 141, 192, 209], 'aggressive': [8], 'behavior.': [9], 'Molecular': [10], 'profile': [11], 'and': [12, 33, 37, 50, 65, 76, 82, 85, 91, 105, 111, 113, 121, 128, 147, 220, 229, 245], 'clinicopathologic': [13, 38], 'features': [14, 39], 'of': [15, 40, 44, 59, 67, 78, 87, 97, 151, 173, 186, 225, 236, 257], 'AMs': [16, 46], 'still': [18], 'not': [19, 132], 'well': [20], 'established.': [21], 'In': [22, 178, 223], 'this': [23], 'study,': [24], 'we': [25], 'aimed': [26], 'to': [27, 197, 241, 246, 254], 'investigate': [28], 'BRAF,': [29], 'NRAS,': [30, 126], 'KIT,': [31], 'TERT,': [32], 'GNAQ/GNA11': [34, 89, 129], 'mutation': [35], 'status': [36], 'AMs.All': [41], 'diagnostic': [42], 'slides': [43], '15': [45, 58], 'were': [47, 53, 109, 116, 131, 154], 'reviewed.': [48], 'Histopathological': [49], 'follow-up': [51, 193], 'information': [52], 'documented.': [54], 'Mutations': [55], 'in': [56, 93, 118, 183, 214, 217], 'exon': [57], 'the': [60, 68, 79, 88, 94, 98, 152, 174, 187, 215, 243, 255], 'BRAF': [61, 228], 'gene;': [62, 70, 81], 'exons': [63, 71, 83], '2': [64], '3': [66], 'NRAS': [69], '9,': [72], '11,': [73], '13,': [74], '17,': [75], '18': [77], 'KIT': [80, 230], '4': [84], '5': [86], 'genes': [90], 'mutations': [92, 115, 130, 231], 'promoter': [95], 'region': [96], 'TERT': [99, 127], 'gene': [100], '(chr.5,': [101], '1,295,228C': [102], '>': [103, 107], 'T': [104], '1,295,250C': [106], 'T)': [108], 'analyzed.BRAF(V600E)': [110], 'KIT(V555I': [112], 'K642E)': [114], 'observed': [117], 'one': [119, 184], '(7%)': [120], 'two': [122], 'cases': [123, 175], '(14%),': [124], 'respectively.': [125], 'detected.': [133, 234], 'The': [134, 157, 199], 'mean': [135, 200], 'age': [136], 'was': [137, 163, 168, 181, 203], '65.': [138], 'Patients': [139], 'presented': [140], 'rectal': [142, 144], 'mass,': [143], 'bleeding,': [145], 'pain,': [146], 'weight': [148], 'loss.': [149], '73%': [150], 'lesions': [153], 'macroscopically': [155], 'polypoid.': [156], 'most': [158], 'common': [159], 'tumor': [160, 166], 'cell': [161], 'type': [162], 'epithelioid.': [164], 'Mean': [165], 'thickness': [167], '10.4': [169], 'mm.': [170], 'One': [171], 'third': [172, 185], 'lacked': [176], 'pigmentation.': [177], 'situ': [179], 'melanoma': [180], 'present': [182], 'cases.': [188], 'Among': [189], '14': [190], 'patients': [191], 'data,': [194], '12': [195], 'succumbed': [196], 'disease.': [198], 'overall': [201], 'survival': [202], '36': [204], 'months.AMs': [205], 'tumors': [208], 'dismal': [210], 'survival,': [211], 'usually': [212], 'occurring': [213], 'elderly': [216], 'various': [218], 'gross': [219], 'microscopic': [221], 'appearances.': [222], 'terms': [224], 'molecular': [226, 249], 'profile,': [227], 'rarely': [233], 'Profiling': [235], 'larger': [237], 'cohorts': [238], 'is': [239], 'required': [240], 'elucidate': [242], 'pathogenesis': [244], 'identify': [247], 'potential': [248], 'indicators': [250], 'that': [251], 'may': [252], 'contribute': [253], 'development': [256], 'individualized': [258], 'targeted': [259], 'therapies.': [260]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4282927540', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}], 'updated_date': '2024-09-12T09:31:34.348308', 'created_date': '2022-06-16'}