Abstract: This chapter explains autonomic disorders, syncope, features of regional autonomic dysfunction and the main conditions seen in an adult general neurology clinic–autonomic failure with Parkinson's, multiple system atrophy and pure autonomic failure. Damage to the autonomic system secondary to neurological disease is typically irreversible and often untreatable. Erectile failure depends in part on the parasympathetic function. Orthostatic hypotension is frequent and may point to an underlying disease. Orthostatic intolerance without hypotension, but with a substantial rise in heart rate, is known as Posturally Induced Tachycardia. Nocturnal polyuria is frequent in primary autonomic failure. Pure autonomic failure is a neurodegenerative disorder characterised by orthostatic hypotension, and once known as Bradbury–Eggleston syndrome from the 1925 description. In idiopathic Parkinson's disease, autonomic features can be present, particularly orthostatic hypotension, made worse by levodopa therapy.
Publication Year: 2022
Publication Date: 2022-05-27
Language: en
Type: other
Indexed In: ['crossref']
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