Title: Defensive chemistry of the Irish nudibranch Archidoris psuedoargus (Gastropoda opisthobranchia)
Abstract:Historically, marine natural products from the Republic of Ireland have been greatly underrepresented in the literature despite having a coastline of over 4500 miles. Archidoris pseudoargus is a soft-...Historically, marine natural products from the Republic of Ireland have been greatly underrepresented in the literature despite having a coastline of over 4500 miles. Archidoris pseudoargus is a soft-bodied, slow moving Dorid nudibranch which inhabits the coastal waters of Ireland and the United Kingdom. Nudibranchs are a good source of new chemical diversity, employing these secondary metabolites to deter predation. In this study we have identified new chemistry as well as used a metabolomics approach to identify the origin of said chemistry as well as trends in morphologically different individuals. From our initial findings the individual organisms group together into several clusters based on their metabolomic profiles (Figure 1 right). The major metabolites isolated thus far from these organisms are diterpene glycerides (e.g., 1 and 2) which have been shown to be icthyotoxins [1] suggesting these metabolites are the nudibranchs method of defense against predation.Read More
Publication Year: 2016
Publication Date: 2016-12-14
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 1
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