Publication Information

{'id': 'https://openalex.org/W4255367289', 'doi': 'https://doi.org/10.1097/mbc.0b013e32801010ce', 'title': 'Influence of coagulation factors on extrinsic thrombin generation', 'display_name': 'Influence of coagulation factors on extrinsic thrombin generation', 'publication_year': 2007, 'publication_date': '2007-02-07', 'ids': {'openalex': 'https://openalex.org/W4255367289', 'doi': 'https://doi.org/10.1097/mbc.0b013e32801010ce', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17287625'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/mbc.0b013e32801010ce', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S118812467', 'display_name': 'Blood Coagulation & Fibrinolysis', 'issn_l': '0957-5235', 'issn': ['0957-5235', '1473-5733'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5032107121', 'display_name': 'T. Stief', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'Thomas W Stief', 'raw_affiliation_strings': ['Accepted 22 August, 2006', 'Department of Clinical Chemistry, University Hospital Marburg, Germany', 'Received 13 June, 2006', 'Revised 15 August, 2006', 'e-mail: [email\xa0protected]', 'fax: +49 6421 286 5594'], 'affiliations': [{'raw_affiliation_string': 'Revised 15 August, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'fax: +49 6421 286 5594', 'institution_ids': []}, {'raw_affiliation_string': 'e-mail: [email\xa0protected]', 'institution_ids': []}, {'raw_affiliation_string': 'Accepted 22 August, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'Received 13 June, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Clinical Chemistry, University Hospital Marburg, Germany', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015917718', 'display_name': 'Aleksandra Wieczerzak', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Aleksandra Wieczerzak', 'raw_affiliation_strings': ['Accepted 22 August, 2006', 'Department of Clinical Chemistry, University Hospital Marburg, Germany', 'Received 13 June, 2006', 'Revised 15 August, 2006', 'e-mail: [email\xa0protected]', 'fax: +49 6421 286 5594'], 'affiliations': [{'raw_affiliation_string': 'Revised 15 August, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'fax: +49 6421 286 5594', 'institution_ids': []}, {'raw_affiliation_string': 'Received 13 June, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'Accepted 22 August, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'e-mail: [email\xa0protected]', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Clinical Chemistry, University Hospital Marburg, Germany', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103039657', 'display_name': 'Harald Renz', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Harald Renz', 'raw_affiliation_strings': ['Accepted 22 August, 2006', 'Department of Clinical Chemistry, University Hospital Marburg, Germany', 'Received 13 June, 2006', 'Revised 15 August, 2006', 'e-mail: [email\xa0protected]', 'fax: +49 6421 286 5594'], 'affiliations': [{'raw_affiliation_string': 'Received 13 June, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'Accepted 22 August, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'Revised 15 August, 2006', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Clinical Chemistry, University Hospital Marburg, Germany', 'institution_ids': ['https://openalex.org/I161103922']}, {'raw_affiliation_string': 'fax: +49 6421 286 5594', 'institution_ids': []}, {'raw_affiliation_string': 'e-mail: [email\xa0protected]', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5032107121'], 'corresponding_institution_ids': ['https://openalex.org/I161103922'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.038, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.691144, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '18', 'issue': '2', 'first_page': '105', 'last_page': '112'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11721', 'display_name': 'Blood properties and coagulation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11721', 'display_name': 'Blood properties and coagulation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10881', 'display_name': 'Blood Coagulation and Thrombosis Mechanisms', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11280', 'display_name': 'Hemophilia Treatment and Research', 'score': 0.9879, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thrombin-generation', 'display_name': 'Thrombin Generation', 'score': 0.52612996}, {'id': 'https://openalex.org/keywords/factor-v', 'display_name': 'Factor V', 'score': 0.44728842}, {'id': 'https://openalex.org/keywords/thromboplastin', 'display_name': 'Thromboplastin', 'score': 0.44136873}], 'concepts': [{'id': 'https://openalex.org/C2777292125', 'wikidata': 'https://www.wikidata.org/wiki/Q409166', 'display_name': 'Thrombin', 'level': 3, 'score': 0.91098106}, {'id': 'https://openalex.org/C2779036427', 'wikidata': 'https://www.wikidata.org/wiki/Q381899', 'display_name': 'Fibrinogen', 'level': 2, 'score': 0.84204805}, {'id': 'https://openalex.org/C2779026020', 'wikidata': 'https://www.wikidata.org/wiki/Q416336', 'display_name': 'Antithrombin', 'level': 3, 'score': 0.77789783}, {'id': 'https://openalex.org/C54173615', 'wikidata': 'https://www.wikidata.org/wiki/Q27205', 'display_name': 'Fibrin', 'level': 2, 'score': 0.77517426}, {'id': 'https://openalex.org/C2778382381', 'wikidata': 'https://www.wikidata.org/wiki/Q179217', 'display_name': 'Coagulation', 'level': 2, 'score': 0.7315291}, {'id': 'https://openalex.org/C186738567', 'wikidata': 'https://www.wikidata.org/wiki/Q412841', 'display_name': 'Tissue factor', 'level': 3, 'score': 0.7237234}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.52827793}, {'id': 'https://openalex.org/C3018972837', 'wikidata': 'https://www.wikidata.org/wiki/Q409166', 'display_name': 'Thrombin generation', 'level': 4, 'score': 0.52612996}, {'id': 'https://openalex.org/C2776046644', 'wikidata': 'https://www.wikidata.org/wiki/Q422831', 'display_name': 'Factor V', 'level': 3, 'score': 0.44728842}, {'id': 'https://openalex.org/C144594695', 'wikidata': 'https://www.wikidata.org/wiki/Q6153218', 'display_name': 'Thromboplastin', 'level': 3, 'score': 0.44136873}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.369051}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.36561793}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.32157087}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.30330443}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.25115252}, {'id': 'https://openalex.org/C2777557582', 'wikidata': 'https://www.wikidata.org/wiki/Q190016', 'display_name': 'Heparin', 'level': 2, 'score': 0.1290445}, {'id': 'https://openalex.org/C89560881', 'wikidata': 'https://www.wikidata.org/wiki/Q101026', 'display_name': 'Platelet', 'level': 2, 'score': 0.10160893}, {'id': 'https://openalex.org/C2780868729', 'wikidata': 'https://www.wikidata.org/wiki/Q261327', 'display_name': 'Thrombosis', 'level': 2, 'score': 0.05130154}], 'mesh': [{'descriptor_ui': 'D001779', 'descriptor_name': 'Blood Coagulation Factors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D001780', 'descriptor_name': 'Blood Coagulation Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D013917', 'descriptor_name': 'Thrombin', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001779', 'descriptor_name': 'Blood Coagulation Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001780', 'descriptor_name': 'Blood Coagulation Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002122', 'descriptor_name': 'Calcium Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005340', 'descriptor_name': 'Fibrinogen', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005340', 'descriptor_name': 'Fibrinogen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013917', 'descriptor_name': 'Thrombin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013925', 'descriptor_name': 'Thromboplastin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/mbc.0b013e32801010ce', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S118812467', 'display_name': 'Blood Coagulation & Fibrinolysis', 'issn_l': '0957-5235', 'issn': ['0957-5235', '1473-5733'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17287625', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.61, 'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 12, 'referenced_works': ['https://openalex.org/W1546296190', 'https://openalex.org/W1997732962', 'https://openalex.org/W2013228274', 'https://openalex.org/W2046997719', 'https://openalex.org/W2063199350', 'https://openalex.org/W2063643460', 'https://openalex.org/W2078132464', 'https://openalex.org/W2082730110', 'https://openalex.org/W2120677427', 'https://openalex.org/W2122004095', 'https://openalex.org/W2140371612', 'https://openalex.org/W2164959456'], 'related_works': ['https://openalex.org/W68354926', 'https://openalex.org/W67173680', 'https://openalex.org/W4214811555', 'https://openalex.org/W2318112513', 'https://openalex.org/W2168645277', 'https://openalex.org/W2098402982', 'https://openalex.org/W2036053622', 'https://openalex.org/W1998816346', 'https://openalex.org/W1879546348', 'https://openalex.org/W1600570099'], 'abstract_inverted_index': {'The': [0, 19, 72, 94, 147], 'extrinsic': [1, 156], 'coagulation': [2], 'activity': [3], 'assay': [4], '(EXCA)': [5], 'is': [6, 74, 96, 149], 'a': [7, 111], 'new': [8], 'thrombin': [9, 44, 60, 91, 114, 119, 127, 139], 'generation': [10, 92, 128], 'test': [11], 'for': [12], 'the': [13, 80, 85, 90, 118, 130, 144, 153], 'tissue': [14, 35], 'factor': [15, 81], 'pathway': [16], 'of': [17, 28, 31, 65, 69, 79, 89, 113, 155], 'coagulation.': [18], 'EXCA': [20, 73, 95, 148], 'was': [21, 61], 'performed': [22], 'with': [23], '10': [24], 'parts': [25], 'citrated': [26], 'plasma': [27], 'different': [29], 'contents': [30], 'fibrinogen.': [32], 'One': [33], 'part': [34], 'factor,': [36], '250': [37], 'mmol/l': [38], 'CaCl(2),': [39], 'generating': [40], 'about': [41], '1': [42, 46], 'IU/ml': [43], 'within': [45], 'min': [47, 53], '(37': [48], 'degrees': [49], 'C).': [50], 'After': [51], '0-30': [52], '2.5': [54], 'mol/l': [55], 'arginine': [56], '(pH': [57], '8.6)': [58], 'Generated': [59], 'detected': [62], 'by': [63], 'addition': [64], 'CHG-Ala-Arg-pNA': [66], 'and': [67, 104], 'measurement': [68], 'triangle': [70], 'upA/t.': [71], 'dependent': [75, 98], 'on': [76, 99], 'factors': [77, 100, 157], '10%': [78], 'VII': [82], 'norm': [83], 'in': [84, 107, 125, 129, 143, 158], 'sample': [86], 'achieves': [87], '70-80%': [88], 'norm.': [93], 'not': [97], 'VIII,': [101], 'IX,': [102], 'XI': [103], 'XII.': [105], 'Even': [106], 'antithrombin': [108, 137], 'III-deficient': [109], 'plasma,': [110], 'phase': [112], 'inhibition': [115], 'appears': [116], 'after': [117], 'peak.': [120], 'Supplemented': [121], 'purified': [122], 'fibrinogen': [123], 'resulted': [124], 'decreased': [126], 'important.': [131], 'Fibrinogen': [132], 'seems': [133], 'to': [134, 151], 'act': [135], 'as': [136], 'I;': [138], 'might': [140], 'be': [141], 'entrapped': [142], 'nascent': [145], 'fibrin.': [146], 'suitable': [150], 'diagnose': [152], 'level': [154], 'patient': [159], 'plasma.': [160]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4255367289', 'counts_by_year': [{'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}], 'updated_date': '2024-12-15T15:42:19.329562', 'created_date': '2022-05-12'}