Title: Cell-Encapsulating Hydrogels for Biosensing
Abstract: Gels Handbook, pp. 327-356 (2016) No AccessChapter 12: Cell-Encapsulating Hydrogels for BiosensingPu Chen, Shuqi Wang, Fatih Inci, Sinan Güven, Savas Tasoglu, and Utkan DemirciPu ChenBio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, School of Medicine, Canary Center for Early Cancer Detection, Stanford University, CA, 94304, USA, Shuqi WangBio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, School of Medicine, Canary Center for Early Cancer Detection, Stanford University, CA, 94304, USAState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, ChinaCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, Zhejiang, 310003, ChinaInstitute for Translational Medicine, Zhejiang University, Hangzhou, Zhejiang, 310029, China, Fatih InciBio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, School of Medicine, Canary Center for Early Cancer Detection, Stanford University, CA, 94304, USA, Sinan GüvenBio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, School of Medicine, Canary Center for Early Cancer Detection, Stanford University, CA, 94304, USA, Savas TasogluBio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, School of Medicine, Canary Center for Early Cancer Detection, Stanford University, CA, 94304, USA, and Utkan DemirciBio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, School of Medicine, Canary Center for Early Cancer Detection, Stanford University, CA, 94304, USAhttps://doi.org/10.1142/9789813140417_0012Cited by:2 (Source: Crossref) PreviousNext AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Library ShareShare onFacebookTwitterLinked InRedditEmail Abstract: Cell-based biosensors (CBBs) are emerging as a sensing platform in which live cells are utilized to sense external stimuli including physical, chemical, and biological changes. Till now, CBBs have demonstrated a broad range of applications including diagnostics, drug screening, environment monitoring, and biosafety monitoring. Although promising, current CBBs are normally based on cells cultured in two-dimensional (2D) surfaces, which brings challenges such as ease of contamination and limited capability for long-time preservation. In addition, cells grown in 2D culture environments cannot fully represent microenvironment in three-dimensional (3D) native tissues and may result in analytical variations such as in drug screening. One potential strategy to overcome these challenges is to incorporate cells in 3D hydrogels, which provide cytocompatible microenvironments for prolonged cell preservation and improved phenotypic similarity with cells in native tissues. In this chapter, we present an overview of cell-encapsulating hydrogel based biosensors (CHBBs) and highlight the unique features of CHBBs as opposed to traditional CBBs. FiguresReferencesRelatedDetailsCited By 2Cited by lists all citing articles based on Crossref citation.Hybrid Living Materials: Digital Design and Fabrication of 3D Multimaterial Structures with Programmable Biohybrid SurfacesRachel Soo Hoo Smith, Christoph Bader, Sunanda Sharma, Dominik Kolb and Tzu‐Chieh Tang et al.18 December 2019 | Advanced Functional Materials, Vol. 30, No. 7On the electrical conductivity of alginate hydrogelsGeorgia Kaklamani, Diana Kazaryan, James Bowen, Fabrice Iacovella and Spiros H Anastasiadis et al.13 August 2018 | Regenerative Biomaterials, Vol. 5, No. 5 Recommended Gels Handbook Metrics History PDF download
Publication Year: 2016
Publication Date: 2016-01-24
Language: en
Type: book-chapter
Indexed In: ['crossref']
Access and Citation
Cited By Count: 3
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