Abstract:Erythema migrans is the most common skin manifestation of Lyme disease caused by <italic>Borrelia</italic> spp. There are some differences in the clinical presentation and aetiology between cases in E...Erythema migrans is the most common skin manifestation of Lyme disease caused by <italic>Borrelia</italic> spp. There are some differences in the clinical presentation and aetiology between cases in Europe and the United States as the vectors and <italic>Borrelia</italic> spp. vary. The diagnosis is usually confirmed by serology, that is, enzyme immune-assay and Western blot, although there are other approaches such as PCR. Apart from erythema migrans, other manifestations include meningitis, heart block, and arthritis. There are a number of options for treatment, including tetracyclines and penicillins, and duration depends on the presence of complications. There is a limited if any role for prophylactic antibiotics to prevent acquisition after exposure to a tick. Much controversy surrounds chronic Lyme disease which may not be a real clinical entity and may mimic other conditions such as connective tissue diseases. There is no evidence that ongoing symptoms are due to persistent infection.Read More
Publication Year: 2020
Publication Date: 2020-02-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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