Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4249252758', 'doi': 'https://doi.org/10.1002/14651858.cd005011.pub2', 'title': 'Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia', 'display_name': 'Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia', 'publication_year': 2007, 'publication_date': '2007-04-03', 'ids': {'openalex': 'https://openalex.org/W4249252758', 'doi': 'https://doi.org/10.1002/14651858.cd005011.pub2'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/14651858.cd005011.pub2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S71429176', 'display_name': 'Cochrane database of systematic reviews', 'issn_l': '1361-6137', 'issn': ['1361-6137', '1469-493X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319727', 'host_organization_name': 'Cochrane', 'host_organization_lineage': ['https://openalex.org/P4310319727'], 'host_organization_lineage_names': ['Cochrane'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'reference-entry', 'type_crossref': 'reference-entry', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://ore.exeter.ac.uk/repository/bitstream/10871/13808/2/Recombinant%20factor%20VIIa%20for%20the%20prevention%20and%20treatment%20of%20bleeding%20in%20patients%20without%20haemophilia.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033353371', 'display_name': 'Yulia Lin', 'orcid': 'https://orcid.org/0000-0002-5562-9020'}, 'institutions': [{'id': 'https://openalex.org/I95297979', 'display_name': 'Canadian Blood Services', 'ror': 'https://ror.org/01jays723', 'country_code': 'CA', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I95297979']}, {'id': 'https://openalex.org/I2802362269', 'display_name': 'Health Sciences Centre', 'ror': 'https://ror.org/05pr37258', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I110535807', 'https://openalex.org/I2802362269']}, {'id': 'https://openalex.org/I1323843004', 'display_name': 'Sunnybrook Health Science Centre', 'ror': 'https://ror.org/03wefcv03', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1323843004']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Yulia Lin', 'raw_affiliation_strings': ['Sunnybrook Health Sciences Centre and Canadian Blood Services'], 'affiliations': [{'raw_affiliation_string': 'Sunnybrook Health Sciences Centre and Canadian Blood Services', 'institution_ids': ['https://openalex.org/I95297979', 'https://openalex.org/I2802362269', 'https://openalex.org/I1323843004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018342534', 'display_name': 'Simon Stanworth', 'orcid': 'https://orcid.org/0000-0002-7414-4950'}, 'institutions': [{'id': 'https://openalex.org/I1307946715', 'display_name': 'NHS Blood and Transplant', 'ror': 'https://ror.org/0227qpa16', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307946715']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Simon Stanworth', 'raw_affiliation_strings': ['NHS Blood and Transplant'], 'affiliations': [{'raw_affiliation_string': 'NHS Blood and Transplant', 'institution_ids': ['https://openalex.org/I1307946715']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068328548', 'display_name': 'Janet Birchall', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1307034911', 'display_name': 'North Bristol NHS Trust', 'ror': 'https://ror.org/036x6gt55', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307034911']}, {'id': 'https://openalex.org/I1307946715', 'display_name': 'NHS Blood and Transplant', 'ror': 'https://ror.org/0227qpa16', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307946715']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Janet Birchall', 'raw_affiliation_strings': ['NHS Blood and Transplant, Bristol and North Bristol NHS Trust'], 'affiliations': [{'raw_affiliation_string': 'NHS Blood and Transplant, Bristol and North Bristol NHS Trust', 'institution_ids': ['https://openalex.org/I1307034911', 'https://openalex.org/I1307946715']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009756710', 'display_name': 'Carolyn Dorée', 'orcid': 'https://orcid.org/0000-0001-6955-7497'}, 'institutions': [{'id': 'https://openalex.org/I1307946715', 'display_name': 'NHS Blood and Transplant', 'ror': 'https://ror.org/0227qpa16', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307946715']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Carolyn Doree', 'raw_affiliation_strings': ['NHS Blood and Transplant'], 'affiliations': [{'raw_affiliation_string': 'NHS Blood and Transplant', 'institution_ids': ['https://openalex.org/I1307946715']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5112834543', 'display_name': 'Chris Hyde', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1307946715', 'display_name': 'NHS Blood and Transplant', 'ror': 'https://ror.org/0227qpa16', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307946715']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Chris Hyde', 'raw_affiliation_strings': ['NHS Blood and Transplant'], 'affiliations': [{'raw_affiliation_string': 'NHS Blood and Transplant', 'institution_ids': ['https://openalex.org/I1307946715']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 255, 'citation_normalized_percentile': {'value': 0.939394, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11280', 'display_name': 'Hemophilia Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11280', 'display_name': 'Hemophilia Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10881', 'display_name': 'Blood Coagulation and Thrombosis Mechanisms', 'score': 0.995, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/recombinant-factor-viia', 'display_name': 'Recombinant Factor VIIa', 'score': 0.627161}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9435898}, {'id': 'https://openalex.org/C2778385053', 'wikidata': 'https://www.wikidata.org/wiki/Q134003', 'display_name': 'Haemophilia', 'level': 2, 'score': 0.78111726}, {'id': 'https://openalex.org/C2777232031', 'wikidata': 'https://www.wikidata.org/wiki/Q2092064', 'display_name': 'Haemophilia A', 'level': 3, 'score': 0.6989242}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.64179033}, {'id': 'https://openalex.org/C2778961111', 'wikidata': 'https://www.wikidata.org/wiki/Q5940878', 'display_name': 'Recombinant factor VIIa', 'level': 2, 'score': 0.627161}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.56580347}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.4512644}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.44884855}, {'id': 'https://openalex.org/C2780014101', 'wikidata': 'https://www.wikidata.org/wiki/Q183605', 'display_name': 'Blood transfusion', 'level': 2, 'score': 0.43485874}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.42622527}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.26627883}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/14651858.cd005011.pub2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S71429176', 'display_name': 'Cochrane database of systematic reviews', 'issn_l': '1361-6137', 'issn': ['1361-6137', '1469-493X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319727', 'host_organization_name': 'Cochrane', 'host_organization_lineage': ['https://openalex.org/P4310319727'], 'host_organization_lineage_names': ['Cochrane'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10871/13808', 'pdf_url': 'https://ore.exeter.ac.uk/repository/bitstream/10871/13808/2/Recombinant%20factor%20VIIa%20for%20the%20prevention%20and%20treatment%20of%20bleeding%20in%20patients%20without%20haemophilia.pdf', 'source': {'id': 'https://openalex.org/S4306401998', 'display_name': 'Open Research Exeter (University of Exeter)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I23923803', 'host_organization_name': 'University of Exeter', 'host_organization_lineage': ['https://openalex.org/I23923803'], 'host_organization_lineage_names': ['University of Exeter'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10871/13808', 'pdf_url': 'https://ore.exeter.ac.uk/repository/bitstream/10871/13808/2/Recombinant%20factor%20VIIa%20for%20the%20prevention%20and%20treatment%20of%20bleeding%20in%20patients%20without%20haemophilia.pdf', 'source': {'id': 'https://openalex.org/S4306401998', 'display_name': 'Open Research Exeter (University of Exeter)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I23923803', 'host_organization_name': 'University of Exeter', 'host_organization_lineage': ['https://openalex.org/I23923803'], 'host_organization_lineage_names': ['University of Exeter'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Zero hunger', 'score': 0.69, 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 85, 'referenced_works': ['https://openalex.org/W1563680939', 'https://openalex.org/W1573466087', 'https://openalex.org/W1598602811', 'https://openalex.org/W1964312531', 'https://openalex.org/W1965036998', 'https://openalex.org/W1965282507', 'https://openalex.org/W1969043817', 'https://openalex.org/W1970269083', 'https://openalex.org/W1972019127', 'https://openalex.org/W1973816939', 'https://openalex.org/W1974124267', 'https://openalex.org/W1976923618', 'https://openalex.org/W1977342673', 'https://openalex.org/W1978720991', 'https://openalex.org/W1978745785', 'https://openalex.org/W1989764409', 'https://openalex.org/W1990867521', 'https://openalex.org/W1995491984', 'https://openalex.org/W1997685722', 'https://openalex.org/W2004602863', 'https://openalex.org/W2004878934', 'https://openalex.org/W2005623034', 'https://openalex.org/W2007654282', 'https://openalex.org/W2009184620', 'https://openalex.org/W2011221519', 'https://openalex.org/W2016676866', 'https://openalex.org/W2020918789', 'https://openalex.org/W2029733999', 'https://openalex.org/W2030183201', 'https://openalex.org/W2031303760', 'https://openalex.org/W2035028304', 'https://openalex.org/W2036920143', 'https://openalex.org/W2041137952', 'https://openalex.org/W2041161523', 'https://openalex.org/W2042828283', 'https://openalex.org/W2046963596', 'https://openalex.org/W2047010931', 'https://openalex.org/W2050848030', 'https://openalex.org/W2052167094', 'https://openalex.org/W2053002269', 'https://openalex.org/W2054077555', 'https://openalex.org/W2055781719', 'https://openalex.org/W2057233679', 'https://openalex.org/W2062498465', 'https://openalex.org/W2063159487', 'https://openalex.org/W2063196253', 'https://openalex.org/W2071195114', 'https://openalex.org/W2074228619', 'https://openalex.org/W2075429091', 'https://openalex.org/W2084006599', 'https://openalex.org/W2088277539', 'https://openalex.org/W2093200845', 'https://openalex.org/W2094585602', 'https://openalex.org/W2101225763', 'https://openalex.org/W2105468396', 'https://openalex.org/W2106659439', 'https://openalex.org/W2108177522', 'https://openalex.org/W2110541674', 'https://openalex.org/W2118420217', 'https://openalex.org/W2119259667', 'https://openalex.org/W2127079299', 'https://openalex.org/W2128749923', 'https://openalex.org/W2133335973', 'https://openalex.org/W2138190464', 'https://openalex.org/W2140699529', 'https://openalex.org/W2140897305', 'https://openalex.org/W2142640478', 'https://openalex.org/W2149761775', 'https://openalex.org/W2158656134', 'https://openalex.org/W2159979050', 'https://openalex.org/W2165755420', 'https://openalex.org/W2170550513', 'https://openalex.org/W2174056266', 'https://openalex.org/W2315102910', 'https://openalex.org/W2383514500', 'https://openalex.org/W2401552686', 'https://openalex.org/W2482236650', 'https://openalex.org/W3021618921', 'https://openalex.org/W3138909697', 'https://openalex.org/W4238103798', 'https://openalex.org/W4238609292', 'https://openalex.org/W4239777602', 'https://openalex.org/W4249059513', 'https://openalex.org/W4249252758', 'https://openalex.org/W575193609'], 'related_works': ['https://openalex.org/W4233505807', 'https://openalex.org/W3155450815', 'https://openalex.org/W2166990743', 'https://openalex.org/W2106659439', 'https://openalex.org/W2101928171', 'https://openalex.org/W2086676349', 'https://openalex.org/W2067082011', 'https://openalex.org/W2005719195', 'https://openalex.org/W1995822104', 'https://openalex.org/W1966293352'], 'abstract_inverted_index': {'Background': [0], 'Recombinant': [1], 'factor': [2], 'VIIa': [3], '(rFVIIa)': [4], 'is': [5, 17, 33, 43], 'licensed': [6, 408], 'for': [7, 22, 152, 354, 371], 'use': [8, 195, 318, 402], 'in': [9, 28, 71, 114, 273, 277, 350], 'patients': [10, 72, 135], 'with': [11, 105, 112, 242, 297], 'haemophilia': [12], 'and': [13, 88, 137, 143, 156, 164, 180, 228], 'inhibitory': [14], 'allo‐antibodies.': [15], 'It': [16], 'also': [18], 'increasingly': [19], 'being': [20], 'used': [21, 59], 'off‐license': [23], 'indications': [24, 409], 'to': [25, 35, 39, 46, 61, 67, 93, 213, 226, 240, 252, 255, 267, 288, 299, 308, 362, 381, 413], 'prevent': [26, 68], 'bleeding': [27, 41, 70], 'operations': [29], 'where': [30, 328], 'blood': [31, 123, 218], 'loss': [32, 124, 219], 'likely': [34, 249], 'be': [36, 411], 'high,': [37], 'and/or': [38], 'stop': [40], 'that': [42], 'proving': [44], 'difficult': [45], 'control': [47, 62, 126], 'by': [48, 343], 'other': [49, 89], 'means.': [50], 'Objectives': [51], 'To': [52], 'assess': [53], 'the': [54, 79, 193, 253, 278, 316], 'effectiveness': [55, 386], 'of': [56, 110, 127, 134, 159, 185, 196, 205, 263, 275, 280, 319, 334, 352, 387, 403], 'rFVIIa': [57, 104, 111, 166, 243, 264, 276, 296, 335, 353, 370, 388, 404], 'when': [58], 'therapeutically': [60], 'active': [63], 'bleeding,': [64, 128], 'or': [65, 107, 125, 332, 397], 'prophylactically': [66, 396], '(excessive)': [69], 'without': [73], 'haemophilia.': [74], 'Search': [75], 'methods': [76], 'We': [77, 161], 'searched': [78], 'Cochrane': [80], 'Injuries': [81], 'Group': [82], 'Specialised': [83], 'Register,': [84], 'CENTRAL,': [85], 'MEDLINE,': [86], 'EMBASE': [87], 'specialised': [90], 'databases': [91], 'up': [92], '25': [94], 'February': [95], '2009.': [96], 'Selection': [97], 'criteria': [98], 'Randomised': [99], 'controlled': [100], 'trials': [101, 188, 259, 311], '(RCTs)': [102], 'comparing': [103], 'placebo,': [106], 'one': [108, 181], 'dose': [109], 'another,': [113], 'any': [115, 329], 'patient': [116], 'population': [117], '(except': [118], 'haemophilia).': [119], 'Outcomes': [120], 'were': [121, 173, 176, 248, 325], 'mortality,': [122], 'red': [129, 230], 'cell': [130, 231], 'transfusion': [131, 232], 'requirements,': [132], 'number': [133, 279], 'transfused': [136, 282], 'thromboembolic': [138, 300, 373], 'adverse': [139, 301, 374], 'events.': [140], 'Data': [141], 'collection': [142], 'analysis': [144], 'Two': [145], 'authors': [146], 'independently': [147], 'assessed': [148], 'potentially': [149], 'relevant': [150], 'studies': [151, 167], 'inclusion,': [153], 'extracted': [154], 'data': [155, 257], 'examined': [157, 192, 315], 'risk': [158], 'bias.': [160], 'considered': [162], 'prophylactic': [163, 194], 'therapeutic': [165, 317], 'separately.': [168], 'Main': [169], 'results': [170], 'Twenty‐five': [171], 'RCTs': [172, 179], 'included:': [174], '24': [175], 'placebo‐controlled': [177], 'double‐blind': [178], 'compared': [182, 266], 'different': [183], 'doses': [184], 'rFVIIa.': [186, 200, 323], 'Fourteen': [187], 'involving': [189, 312], '1137': [190], 'participants': [191, 281, 314], 'rFVIIa;': [197, 320], '713': [198], 'received': [199, 322], 'There': [201, 215, 269, 324, 346], 'was': [202, 216, 270, 292, 347, 366], 'no': [203, 261, 326], 'evidence': [204], 'mortality': [206, 356], 'benefit': [207], '(RR': [208, 283, 303, 357, 376], '1.06;': [209], '95%': [210, 223, 237, 285, 305, 359, 378], 'CI': [211, 224, 238, 286, 306, 360, 379], '0.50': [212], '2.24).': [214], 'decreased': [217, 229], '(WMD': [220, 234], '‐272': [221], 'mL;': [222, 236], '‐399': [225], '‐146)': [227], 'requirements': [233], '‐243': [235], '‐393': [239], '‐92)': [241], 'treatment;': [244], 'however': [245], 'these': [246], 'values': [247], 'overestimated': [250], 'due': [251], 'inability': [254], 'incorporate': [256], 'from': [258], 'showing': [260], 'difference': [262], 'treatment': [265], 'placebo.': [268], 'a': [271, 293, 348, 367, 390], 'trend': [272, 294, 349, 368], 'favour': [274, 351], '0.91;': [284], '0.82': [287], '1.02).': [289], 'But': [290], 'there': [291, 365], 'against': [295, 369], 'respect': [298], 'events': [302, 375], '1.32;': [304], '0.84': [307], '2.06).': [309], 'Eleven': [310], '2366': [313], '1507': [321], 'outcomes': [327], 'observed': [330, 342], 'advantage,': [331], 'disadvantage,': [333], 'over': [336], 'placebo': [337], 'could': [338], 'not': [339], 'have': [340], 'been': [341], 'chance': [344], 'alone.': [345], 'reducing': [355], '0.89;': [358], '0.77': [361], '1.03).': [363], 'However,': [364], 'increased': [372], '1.21;': [377], '0.93': [380], '1.58).': [382], "Authors'": [383], 'conclusions': [384], 'The': [385, 401], 'as': [389], 'more': [391], 'general': [392], 'haemostatic': [393], 'drug,': [394], 'either': [395], 'therapeutically,': [398], 'remains': [399], 'unproven.': [400], 'outside': [405], 'its': [406], 'current': [407], 'should': [410], 'restricted': [412], 'clinical': [414], 'trials.': [415]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4249252758', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 14}, {'year': 2016, 'cited_by_count': 20}, {'year': 2015, 'cited_by_count': 18}, {'year': 2014, 'cited_by_count': 25}, {'year': 2013, 'cited_by_count': 23}, {'year': 2012, 'cited_by_count': 18}], 'updated_date': '2024-12-12T19:54:20.326193', 'created_date': '2022-05-12'}