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'Zietman': [108, 1885], 'CarrollPeter': [112], 'View': [114], 'All': [115, 1918], 'Author': [116], 'Informationhttps://doi.org/10.1016/j.juro.2012.11.014AboutFull': [117], 'TextPDF': [118], 'ToolsAdd': [119], 'to': [120, 200, 256, 280, 282, 344, 425, 575, 961, 1659], 'favoritesDownload': [121], 'CitationsTrack': [122], 'CitationsPermissionsReprints': [123], 'ShareFacebookLinked': [124], 'InTwitterEmail': [125], 'Abstract': [126], 'Purpose:': [127], 'We': [128], 'provide': [129, 1486], 'current': [130, 184, 243, 261], 'information': [131], 'on': [132, 179, 289, 335, 418, 461, 1122, 1675, 1708], 'the': [133, 139, 149, 165, 183, 190, 223, 242, 246, 260, 278, 329, 357, 368, 426, 436, 442, 462, 470, 617, 640, 676, 700, 753, 932, 955, 1008, 1100, 1123, 1141, 1253, 1304, 1355, 1367, 1386], 'use': [134], 'PSA': [136, 169, 252, 290, 308, 310, 439, 459, 637, 775, 1160, 1484], 'testing': [137], 'for': [138, 145, 205, 248, 378, 621, 661, 682, 718, 893, 938, 1055, 1081, 1162, 1177, 1334, 1363, 1373, 1382, 1411, 1429, 1512, 1593], 'evaluation': [140, 812], 'men': [142, 352, 380, 556, 771, 819, 1025, 1065, 1534], 'at': [143, 1167], 'risk': [144, 641, 1063, 1104], 'prostate': [146, 275, 283, 332, 340, 362, 383, 444, 467, 493, 513, 559, 583, 623, 645, 662, 747, 814, 823, 834, 838, 845, 860, 894, 910, 920, 939, 965, 1022, 1061, 1102, 1126, 1163, 1178, 1199, 1203, 1299, 1320, 1339, 1365, 1371, 1375, 1404, 1432, 1463, 1494, 1561, 1574, 1594], 'cancer,': [147], 'risks': [150, 358], 'benefits': [152, 360, 1158], 'early': [154, 492, 744], 'detection.': [155], 'Materials': [156], 'Methods:': [158], 'The': [159, 174, 1118, 1267, 1315, 1702], 'report': [160, 1379], 'is': [161, 177, 198, 1165, 1272], 'a': [162, 180, 194, 203, 217, 250, 266, 393, 473, 528, 793, 867, 1027, 1301, 1342, 1383, 1409, 1412, 1471, 1663, 1713], 'summary': [163, 175, 1302], 'American': [166, 1368, 1611, 1622, 1752], 'Urological': [167, 1369, 1612, 1623, 1753], 'Association': [168, 1370, 1613, 1624, 1754], 'Policy': [172], '2009.': [173], 'statement': [176], 'based': [178, 287, 1206], 'review': [181, 882], 'professional': [185], 'literature,': [186], 'clinical': [187, 573, 1458], 'experience': [188], 'expert': [191], 'opinions': [192], 'multispecialty': [195], 'panel.': [196], 'It': [197, 213], 'intended': [199], 'serve': [201], 'as': [202, 891, 1058], 'resource': [204], 'physicians,': [206], 'other': [207, 1770, 1784, 1812, 1850, 1865, 1888, 1904], 'health': [208], 'care': [209, 227], 'professionals,': [210], 'patients.': [212, 350], 'does': [214], 'not': [215], 'establish': [216], 'fixed': [218], 'set': [219], 'guidelines,': [221], 'define': [222], 'legal': [224], 'standard': [225, 1384], 'or': [228, 780, 1032, 1600], 'pre-empt': [229], 'physician': [230], 'judgment': [231], 'in': [232, 241, 373, 392, 441, 469, 491, 515, 555, 602, 625, 675, 696, 704, 716, 743, 770, 792, 818, 844, 1064, 1084, 1227, 1252, 1319, 1354, 1360, 1385, 1460, 1491, 1533, 1712], 'individual': [233], 'cases.': [234], 'Results:': [235], 'There': [236], 'are': [237], 'two': [238], 'notable': [239], 'differences': [240, 715], 'policy.': [244], 'First,': [245], 'age': [247, 906, 1056], 'obtaining': [249], 'baseline': [251], 'has': [253], 'been': [254], 'lowered': [255], '40': [257, 1313], 'years.': [258], 'Secondly,': [259], 'policy': [262], 'no': [263], 'longer': [264], 'recommends': [265], 'single,': [267], 'threshold': [268, 913], 'value': [269], 'PSA,': [271, 305, 720, 722], 'which': [272], 'should': [273, 285, 295, 353], 'prompt': [274], 'biopsy.': [276], 'Rather,': [277], 'decision': [279], 'proceed': [281], 'biopsy': [284, 316, 366], 'be': [286, 354], 'primarily': [288], 'DRE': [292], 'results,': [293], 'but': [294], 'take': [296], 'into': [297], 'account': [298], 'multiple': [299], 'factors': [300], 'including': [301], 'free': [302, 721, 726, 958], 'total': [304, 719, 986, 1000], 'patient': [306], 'age,': [307], 'velocity,': [309], 'density,': [311], 'family': [312], 'history,': [313], 'ethnicity,': [314], 'prior': [315], 'history': [317], 'comorbidities.': [319], 'Conclusions:': [320], 'Although': [321], 'recently': [322], 'published': [323], 'trials': [324], 'show': [325], 'different': [326, 1168], 'results': [327, 526, 671, 717, 1006], 'regarding': [328], 'impact': [330], 'cancer': [333, 341, 363, 445, 468, 514, 597, 624, 646, 663, 846, 861, 940, 966, 1023, 1062, 1103, 1139, 1164, 1200, 1340, 1376, 1405, 1433, 1464], 'screening': [334, 342, 364, 440, 460, 531, 1161], 'mortality,': [336], 'both': [337], 'suggest': [338], 'that': [339, 1455], 'leads': [343], 'overdetection': [345], 'overtreatment': [347], 'some': [349], 'Therefore,': [351], 'informed': [355], 'before': [365], 'option': [369], 'active': [371], 'surveillance': [372, 474], 'lieu': [374], 'immediate': [376], 'treatment': [377, 508, 1157], 'certain': [379], 'diagnosed': [381, 1298], 'with': [382, 507, 547, 557, 772, 820, 862, 1026, 1051, 1336, 1435, 1462, 1466, 1535, 1670, 1772, 1786, 1814, 1852, 1867, 1890, 1906], 'cancer.': [384, 494, 560, 584, 895, 921, 1127, 1321, 1495, 1562], 'References': [385], '1': [386], ':': [387, 406, 434, 456, 485, 504, 524, 542, 570, 591, 614, 635, 659, 693, 713, 737, 764, 788, 810, 831, 856, 880, 904, 930, 952, 977, 1019, 1046, 1077, 1096, 1117, 1137, 1154, 1195, 1216, 1241, 1266, 1293, 1314, 1331, 1352, 1399, 1423, 1450, 1483, 1502, 1524, 1547, 1571, 1589], 'Screening': [388, 660, 681, 1176, 1706, 1711], 'prostate-cancer': [390, 530], 'mortality': [391, 446, 1508, 1576, 1596], 'randomized': [394, 529], 'European': [395, 626, 677, 1011], 'study.': [396], 'N': [397, 495, 533, 561, 650, 1037, 1087, 1128], 'Engl': [398, 496, 534, 562, 651, 1038, 1088, 1129], 'J': [399, 497, 535, 563, 606, 652, 729, 755, 848, 871, 896, 922, 1039, 1089, 1107, 1130, 1145, 1208, 1233, 1259, 1285, 1306, 1391, 1415, 1440, 1475, 1516, 1563, 1603], 'Med2009;': [400, 536], '360:': [401, 537], '11320.': [402], 'Google': [403, 431, 453, 482, 501, 521, 539, 567, 588, 611, 632, 656, 690, 710, 734, 761, 785, 807, 828, 853, 877, 901, 927, 949, 974, 1016, 1043, 1074, 1093, 1114, 1134, 1151, 1173, 1192, 1213, 1238, 1263, 1290, 1311, 1328, 1349, 1396, 1420, 1447, 1480, 1499, 1521, 1544, 1568, 1586, 1609], 'Scholar': [404, 432, 454, 483, 502, 522, 540, 568, 589, 612, 633, 657, 691, 711, 735, 762, 786, 808, 829, 854, 878, 902, 928, 950, 975, 1017, 1044, 1075, 1094, 1115, 1135, 1152, 1174, 1193, 1214, 1239, 1264, 1291, 1312, 1329, 1350, 1397, 1421, 1448, 1481, 1500, 1522, 1545, 1569, 1587, 1610], '2': [405], 'SEER': [407, 421, 427], 'Cancer': [408, 414, 448, 684, 757, 873, 1147, 1217, 1605, 1674, 1710, 1792, 1908], 'Statistics': [409], 'Review,': [410], '1975–2005.': [411], 'Bethesda:': [412], 'National': [413, 1791, 1907], 'Institute': [415], 'http://seer.cancer.gov/csr/1975_2005/.': [416], 'Based': [417], 'November': [419], '2007': [420], 'data': [422], 'submission': [423], 'posted': [424], 'web': [428], 'site': [429], '2008.': [430], '3': [433], 'Quantifying': [435], 'role': [437, 1316], 'US': [443], 'decline.': [447], 'Causes': [449], 'Control2008;': [450], '19:': [451], '175.': [452], '4': [455], 'Impact': [457, 1703], 'incidence': [463], 'advanced': [465, 1338], 'stage': [466], 'United': [471], 'States:': [472], 'modeling': [475], 'approach.': [476], 'Med': [477], 'Decis': [478], 'Making2003;': [479], '28:': [480], '323.': [481], '5': [484], 'Radical': [486], 'prostatectomy': [487, 551, 604, 1226, 1599], 'versus': [488], 'watchful': [489], 'waiting': [490], 'Med2005;': [498], '352:': [499], '1977.': [500], '6': [503], 'Survival': [505], 'associated': [506], 'vs.': [509, 1531], 'observation': [510, 548, 1532], 'localized': [512, 1364, 1374], 'elderly': [516], 'men.': [517, 627, 1086], 'JAMA2006;': [518], '296:': [519], '2683.': [520], '7': [523], 'Mortality': [525], 'from': [527, 644, 967, 1099], 'trial.': [532, 1012, 1106], '1310.': [538], '8': [541], 'Immediate': [543], 'hormonal': [544, 1510], 'therapy': [545, 1511], 'compared': [546, 1050], 'after': [549, 647, 672, 1406, 1538, 1580, 1597], 'radical': [550, 603, 648, 1224, 1283, 1407, 1539, 1549, 1581, 1598], 'pelvic': [553, 1243, 1249], 'lymphadenectomy': [554, 1250, 1318], 'node-positive': [558], 'Med1999;': [564], '341:': [565], '1781.': [566], '9': [569], 'Pathological': [571, 1196], 'findings': [574], 'predict': [576, 1457], 'tumor': [577], 'extent': [578], 'nonpalpable': [580], '(stage': [581], 'T1c)': [582], 'JAMA1994;': [585], '271:': [586], '368.': [587], '10': [590], 'Preoperative': [592, 636], 'prediction': [593, 1488], 'small': [595], 'volume': [596], '(less': [598], 'than': [599, 1067], '0.5': [600], 'ml)': [601], 'specimens.': [605], 'Urol2005;': [607, 1286, 1325, 1476], '174:': [608, 1287], '898.': [609], 'Link,': [610, 852, 926, 1113, 1212, 1237, 1289, 1310, 1395, 1479, 1567], '11': [613], 'Validation': [615], 'contemporary': [618], 'Epstein': [619], 'criteria': [620], 'insignificant': [622], 'Eur': [628, 1345], 'Urol2008;': [629, 1346], '54:': [630, 1347], '1306.': [631], '12': [634], 'velocity': [638, 741, 841, 865, 887, 937], 'death': [643], 'prostatectomy.': [649, 1284, 1540, 1582], 'Med2004;': [653, 1040], '351:': [654], '125.': [655], '13': [658], 'without': [664, 822], 'digital': [665], 'rectal': [666], 'examination': [667], 'transrectal': [669], 'ultrasound:': [670], 'four': [673], 'years': [674, 1069], 'Randomized': [678], 'Study': [679], 'Prostate': [683, 1138, 1525, 1673, 1709], '(ERSPC),': [685], 'Rotterdam.': [686], 'Prostate2006;': [687], '66:': [688, 1171], '625.': [689], '14': [692], 'Prostate-specific': [694, 1503], 'antigen': [695, 740, 769, 791, 816, 836, 840, 864, 886, 912, 936, 960, 983, 992, 996, 1029, 1049, 1054, 1083, 1205, 1270, 1278, 1504, 1514], 'hemodialysis': [697], 'patients': [698, 1335, 1361, 1461], 'influence': [701, 1119], 'dialysis': [703], 'its': [705], 'levels.': [706], 'Nephron2002;': [707], '90:': [708], '230.': [709], '15': [712], 'Intermethod': [714], 'percentage': [724, 956], 'PSA.': [727], 'Am': [728], 'Clin': [730, 897, 1323, 1416, 1517], 'Pathol2008;': [731], '129:': [732], '952.': [733], '16': [736], 'Is': [738, 931], 'prostate-specific': [739, 768, 790, 863, 885, 935, 959, 979, 982, 991, 995, 1004, 1028, 1048, 1053, 1082, 1513], 'useful': [742], 'detection': [745, 941], 'cancer?:': [748], 'A': [749, 1648], 'critical': [750], 'appraisal': [751], 'evidence.': [754], 'Natl': [756, 872, 1146, 1604], 'Inst2007;': [758], '99:': [759], '1510.': [760], '17': [763], 'Operating': [765], 'characteristics': [766, 1197], 'an': [773], 'initial': [774], 'level': [776, 1030], '3.0': [778], 'ng/mL': [779], 'lower.': [781], 'JAMA2005;': [782, 1583], '294:': [783, 1584], '66.': [784], '18': [787], 'Serum': [789], 'community-based': [794], 'population': [795], 'healthy': [797], 'men:': [798], 'Establishment': [799], 'age-specific': [801], 'reference': [802, 1079], 'ranges.': [803], 'JAMA1993;': [804], '270:': [805], '860.': [806], '19': [809], 'Longitudinal': [811], 'specific': [815, 835, 839, 911, 1204, 1269, 1277], 'levels': [817], 'disease.': [824], 'JAMA1992;': [825], '267:': [826], '2215.': [827], '20': [830], 'Age': [832], 'adjusted': [833, 909], 'cut': [842], 'points': [843], 'screening.': [847, 1207], 'Urol2007;': [849, 923, 1392], '177:': [850, 1393], '499.': [851], '21': [855], 'Detection': [857], 'life-threatening': [859], 'during': [866], 'window': [868], 'curability.': [870], 'Inst2006;': [874], '98:': [875], '1521.': [876], '22': [879], 'Systematic': [881], 'pretreatment': [884], 'doubling': [889], 'time': [890], 'predictors': [892], 'Oncol2009;': [898], '27:': [899], '398.': [900], '23': [903], 'Current': [905], 'race': [908], 'values': [914], 'delay': [915], 'diagnosis': [916], 'high': [918], 'grade': [919], '178:': [924], '1929.': [925], '24': [929], 'utility': [933], 'affected': [942], 'by': [943, 1621, 1751, 1776, 1804, 1819, 1827, 1835, 1842, 1857, 1873, 1881, 1897, 1914], 'age?.': [944], 'BJU': [945], 'Int2008;': [946], '101:': [947], '817.': [948], '25': [951], 'Use': [953], 'enhance': [962], 'differentiation': [963], 'benign': [968], 'prostatic': [969, 1256, 1268, 1276], 'diseases.': [970], 'JAMA1998;': [971], '279:': [972], '1542.': [973], '26': [976], 'Complexed': [978], 'antigen,': [980], 'complexed': [981], 'density': [984, 998], 'transition': [988, 1002], 'zone,': [989], 'complexed/total': [990], 'ratio,': [993, 997], 'free-to-total': [994], 'zone': [1003], 'antigen:': [1005], 'prospective': [1009], 'multicenter': [1010], 'Urology2002;': [1013], '60:': [1014], '4.': [1015], '27': [1018], 'Prevalence': [1020], 'among': [1024, 1662], '<': [1031], '=4.0': [1033], 'ng': [1034], 'per': [1035], 'milliliter.': [1036], '350:': [1041], '2239.': [1042], '28': [1045], 'Baseline': [1047, 1294], 'median': [1052], 'group': [1057], 'predictor': [1059], 'younger': [1066], '60': [1068], 'old.': [1070], 'Urology2006;': [1071], '67:': [1072, 1445], '316.': [1073], '29': [1076], 'Age-specific': [1078], 'ranges': [1080], 'black': [1085], 'Med1996;': [1090], '335:': [1091], '304.': [1092], '30': [1095], 'Further': [1097], 'analyses': [1098], 'REDUCE': [1101], 'reduction': [1105], 'Urol2009;': [1108], '181:': [1109], '555.': [1110], 'abstract': [1111], 'LBA1.': [1112], '31': [1116], 'finasteride': [1121], 'development': [1124], 'Med2003;': [1131], '349:': [1132], '215.': [1133], '32': [1136], 'Will': [1142], 'Rogers': [1143], 'phenomenon.': [1144], 'Inst2005;': [1148], '97:': [1149], '1248.': [1150], '33': [1153], 'Estimation': [1155], 'when': [1159], 'discontinued': [1166], 'ages.': [1169], 'Urology2005;': [1170], '1038.': [1172], '34': [1175], 'cancer:': [1179, 1300, 1366], 'U.S.': [1180], 'Preventive': [1181], 'Services': [1182], 'Task': [1183], 'Force': [1184], 'recommendation': [1185], 'statement.': [1186], 'Intern': [1188], 'Med2008;': [1189], '149:': [1190], '185.': [1191], '35': [1194], 'detected': [1201], 'through': [1202], 'Urol2006;': [1209, 1564], '175:': [1210], '902.': [1211], '36': [1215], 'progression': 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