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'working': [30], 'as': [31, 146, 165], 'microRNA': [32], '(miRNA)': [33], 'sponges': [34], 'to': [35, 76, 119, 124, 150], 'regulate': [36], 'gene': [37], 'expression.': [38], 'However,': [39], 'the': [40, 78, 98, 126], 'role': [41], 'potential': [43], 'molecular': [44], 'mechanism': [45], 'circRNAs': [47], 'remain': [51], 'largely': [52], 'unknown.MethodsCircPTK2': [53], '(hsa_circ_0005273)': [54], 'was': [55, 87], 'identified': [56], 'by': [57, 62], 'bioinformatics': [58], 'analysis': [59], 'validated': [61], 'RT-qPCR': [63], 'assay.': [64], 'Bioinformatics': [65], 'prediction,': [66], 'dual-luciferase': [67], 'reporter': [68], 'RNA': [70], 'pull': [71], 'down': [72], 'assays': [73], 'were': [74], 'used': [75], 'determine': [77], 'interaction': [79], 'between': [80], 'circPTK2,': [81], 'miR-196a-3p,': [82], 'AATK.ResultsThe': [83], 'level': [84], 'circPTK2': [86, 96, 110, 115, 132, 144, 162], 'markedly': [88], 'downregulated': [89], 'tissues.': [93], 'Upregulation': [94], 'suppressed': [97], 'proliferation,': [99], 'migration': [100], 'invasion': [102], 'cells,': [106], 'while': [107], 'downregulation': [108], 'exhibited': [111], 'opposite': [112], 'effects.': [113], 'Mechanically,': [114], 'could': [116], 'competitively': [117], 'bind': [118], 'miR-196a-3p': [120, 123], 'prevent': [122], 'reduce': [125], 'expression': [127], 'AATK.': [129], 'In': [130], 'addition,': [131], 'overexpression': [133], 'inhibited': [134], 'tumorigenesis': [135], 'xenograft': [138], 'mouse': [139], 'model': [140], 'cancer.ConclusionCollectively,': [143], 'suppressor': [149], 'suppress': [151], 'cell': [154], 'proliferation': [155], 'through': [156], 'regulating': [157], 'miR-196a-3p/AATK': [158], 'axis,': [159], 'suggesting': [160], 'may': [163], 'serve': [164], 'novel': [166], 'therapeutic': [167], 'target': [168], 'for': [169], 'cancer.': [171]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4246363308', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}], 'updated_date': '2024-08-31T06:14:46.756346', 'created_date': '2022-05-12'}