Abstract:This chapter provides an overview on some aspects of the chemistry of various selected non-classical N-heterocyclic carbenes (NHCs). Formal replacement of nitrogen with an oxygen atom in the stereotyp...This chapter provides an overview on some aspects of the chemistry of various selected non-classical N-heterocyclic carbenes (NHCs). Formal replacement of nitrogen with an oxygen atom in the stereotypical NHCs would result in the oxygen-containing N,O-heterocyclic carbenes (NOHCs). The in situ generation of NOHCs free can be achieved with an external base in analogy to common NHCs. The NOHCs generated in situ easily replace the much weaker acetone donors from the platinum(IV) center. One of the simple ways to modify the stereotypical five-membered NHCs is to extend the ring size. In doing so, cyclic diaminocarbenes with six-, seven- and even eightmembered rings can be obtained as representatives of the so-called expanded-ring NHCs. A special type of expanded-ring NHCs are the so-called diamidocarbenes (DAC). The electron-withdrawing nature of amide groups in these carbenes increases the electrophilicity and reduces the nucleophilicity of the donor atom.Read More
Publication Year: 2017
Publication Date: 2017-01-27
Language: en
Type: other
Indexed In: ['crossref']
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