Publication Information

{'id': 'https://openalex.org/W4239727325', 'doi': 'https://doi.org/10.1002/9780470015902.a0005721.pub3', 'title': 'Protein Folding and Chaperones', 'display_name': 'Protein Folding and Chaperones', 'publication_year': 2015, 'publication_date': '2015-04-14', 'ids': {'openalex': 'https://openalex.org/W4239727325', 'doi': 'https://doi.org/10.1002/9780470015902.a0005721.pub3'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/9780470015902.a0005721.pub3', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4363604175', 'display_name': 'Encyclopedia of Life Sciences', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': True, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'other', 'type_crossref': 'other', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5008048446', 'display_name': 'Tessa Sinnige', 'orcid': 'https://orcid.org/0000-0002-9353-126X'}, 'institutions': [{'id': 'https://openalex.org/I193662353', 'display_name': 'Utrecht University', 'ror': 'https://ror.org/04pp8hn57', 'country_code': 'NL', 'type': 'funder', 'lineage': ['https://openalex.org/I193662353']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Tessa Sinnige', 'raw_affiliation_strings': ['Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands', 'institution_ids': ['https://openalex.org/I193662353']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075205750', 'display_name': 'G. Elif Karagöz', 'orcid': 'https://orcid.org/0000-0002-3392-2250'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'funder', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'G Elif Karagöz', 'raw_affiliation_strings': ['University of California, San Francisco, California, USA'], 'affiliations': [{'raw_affiliation_string': 'University of California, San Francisco, California, USA', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5064132846', 'display_name': 'Stefan Rüdiger', 'orcid': 'https://orcid.org/0000-0002-1807-2972'}, 'institutions': [{'id': 'https://openalex.org/I193662353', 'display_name': 'Utrecht University', 'ror': 'https://ror.org/04pp8hn57', 'country_code': 'NL', 'type': 'funder', 'lineage': ['https://openalex.org/I193662353']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Stefan GD Rüdiger', 'raw_affiliation_strings': ['Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Cellular Protein Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands', 'institution_ids': ['https://openalex.org/I193662353']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': None, 'issue': None, 'first_page': '1', 'last_page': '8'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10934', 'display_name': 'Heat shock proteins research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10934', 'display_name': 'Heat shock proteins research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure and Dynamics', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/co-chaperone', 'display_name': 'Co-chaperone', 'score': 0.91968656}, {'id': 'https://openalex.org/keywords/chaperone', 'display_name': 'Chaperone (clinical)', 'score': 0.876367}, {'id': 'https://openalex.org/keywords/chaperonin', 'display_name': 'Chaperonin', 'score': 0.7961153}, {'id': 'https://openalex.org/keywords/chemical-chaperone', 'display_name': 'Chemical chaperone', 'score': 0.58256173}], 'concepts': [{'id': 'https://openalex.org/C141109615', 'wikidata': 'https://www.wikidata.org/wiki/Q5137430', 'display_name': 'Co-chaperone', 'level': 5, 'score': 0.91968656}, {'id': 'https://openalex.org/C2775962898', 'wikidata': 'https://www.wikidata.org/wiki/Q5073152', 'display_name': 'Chaperone (clinical)', 'level': 2, 'score': 0.876367}, {'id': 'https://openalex.org/C204328495', 'wikidata': 'https://www.wikidata.org/wiki/Q847556', 'display_name': 'Protein folding', 'level': 2, 'score': 0.808269}, {'id': 'https://openalex.org/C85755625', 'wikidata': 'https://www.wikidata.org/wiki/Q24771589', 'display_name': 'Chaperonin', 'level': 3, 'score': 0.7961153}, {'id': 'https://openalex.org/C61397870', 'wikidata': 'https://www.wikidata.org/wiki/Q1069458', 'display_name': 'Chemical chaperone', 'level': 4, 'score': 0.58256173}, {'id': 'https://openalex.org/C205260736', 'wikidata': 'https://www.wikidata.org/wiki/Q418939', 'display_name': 'Heat shock protein', 'level': 3, 'score': 0.5696764}, {'id': 'https://openalex.org/C2775932338', 'wikidata': 'https://www.wikidata.org/wiki/Q24772687', 'display_name': 'Hsp90', 'level': 4, 'score': 0.521103}, {'id': 'https://openalex.org/C68991219', 'wikidata': 'https://www.wikidata.org/wiki/Q419102', 'display_name': 'Hsp70', 'level': 4, 'score': 0.4721161}, {'id': 'https://openalex.org/C47701112', 'wikidata': 'https://www.wikidata.org/wiki/Q735188', 'display_name': 'Protein structure', 'level': 2, 'score': 0.4419402}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42217937}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40229833}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3985827}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.36100876}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.34002042}, {'id': 'https://openalex.org/C139447449', 'wikidata': 'https://www.wikidata.org/wiki/Q14633900', 'display_name': 'Unfolded protein response', 'level': 3, 'score': 0.14400345}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.07286236}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/9780470015902.a0005721.pub3', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4363604175', 'display_name': 'Encyclopedia of Life Sciences', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': True, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.6, 'display_name': 'Zero hunger', 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 41, 'referenced_works': ['https://openalex.org/W1529921298', 'https://openalex.org/W1541948779', 'https://openalex.org/W1588812136', 'https://openalex.org/W1965754110', 'https://openalex.org/W1967960279', 'https://openalex.org/W1970577444', 'https://openalex.org/W1972121275', 'https://openalex.org/W1977898751', 'https://openalex.org/W1978033776', 'https://openalex.org/W1980505864', 'https://openalex.org/W1990292742', 'https://openalex.org/W1993050837', 'https://openalex.org/W1994584547', 'https://openalex.org/W1997718936', 'https://openalex.org/W2003129326', 'https://openalex.org/W2004821895', 'https://openalex.org/W2008217034', 'https://openalex.org/W2014050554', 'https://openalex.org/W2014095962', 'https://openalex.org/W2032311486', 'https://openalex.org/W2045777307', 'https://openalex.org/W2046629597', 'https://openalex.org/W2052595824', 'https://openalex.org/W2059277971', 'https://openalex.org/W2065504621', 'https://openalex.org/W2081457168', 'https://openalex.org/W2084273798', 'https://openalex.org/W2088511593', 'https://openalex.org/W2093169681', 'https://openalex.org/W2109553859', 'https://openalex.org/W2122550753', 'https://openalex.org/W2136597136', 'https://openalex.org/W2140197221', 'https://openalex.org/W2140634486', 'https://openalex.org/W2142338805', 'https://openalex.org/W2143575872', 'https://openalex.org/W2147984622', 'https://openalex.org/W2149505288', 'https://openalex.org/W2164897290', 'https://openalex.org/W2165581033', 'https://openalex.org/W2166564727'], 'related_works': ['https://openalex.org/W414102696', 'https://openalex.org/W2464418635', 'https://openalex.org/W2211730533', 'https://openalex.org/W2123571077', 'https://openalex.org/W2119225418', 'https://openalex.org/W2093169681', 'https://openalex.org/W2090900356', 'https://openalex.org/W2079336387', 'https://openalex.org/W2018641097', 'https://openalex.org/W1687473291'], 'abstract_inverted_index': {'Abstract': [0], 'Proteins': [1, 139], 'fold': [2, 140], 'via': [3, 141], 'specific': [4], 'pathways': [5], 'to': [6, 41, 47], 'achieve': [7], 'their': [8], 'native': [9], 'structure.': [10], 'Protein': [11, 24, 143, 147], 'structures': [12, 144], 'are,': [13, 38], 'however,': [14], 'inherently': [15], 'unstable,': [16], 'hence': [17], 'folding': [18, 45, 51, 126, 148, 158], 'and': [19, 46, 83, 102, 124, 134, 173, 180], 'unfolding': [20], 'are': [21, 58, 68, 92, 111, 127, 145, 164], 'in': [22, 44, 130, 149, 178], 'equilibrium.': [23], 'instability': [25], 'is': [26, 151, 169], 'a': [27], 'major': [28], 'concern': [29], 'inside': [30], 'the': [31, 80, 88, 119], 'cell.': [32], 'Specialised': [33], 'proteins': [34, 43], 'called': [35], 'molecular': [36, 116, 135, 154], 'chaperones': [37, 57, 123, 163], 'therefore,': [39], 'required': [40], 'assist': [42], 'prevent': [48], 'aggregation': [49], 'of': [50, 56, 63, 66, 85, 87, 118, 121], 'intermediates.': [52], 'Many': [53], 'different': [54], 'classes': [55, 91, 98], 'conserved': [59], 'throughout': [60], 'all': [61, 104], 'kingdoms': [62], 'life,': [64], 'many': [65], 'which': [67], 'known': [69], 'as': [70], 'heat': [71], 'shock': [72], 'proteins.': [73], 'Chaperones': [74], 'typically': [75], 'recognise': [76], 'hydrophobic': [77], 'patches,': [78], 'but': [79], 'exact': [81], 'functions': [82], 'mechanisms': [84], 'action': [86], 'various': [89], 'chaperone': [90, 97], 'very': [93], 'different.': [94], 'The': [95, 115], 'main': [96], 'Hsp70,': [99], 'Hsp90,': [100], 'Hsp100': [101], 'chaperonins': [103], 'depend': [105], 'on': [106], 'ATPase': [107], 'cycles,': [108], 'whose': [109], 'activities': [110], 'fine‐tuned': [112], 'by': [113, 153, 171], 'co‐chaperones.': [114], 'understanding': [117], 'mechanism': [120], 'both': [122], 'protein': [125, 157], 'key': [128], 'problems': [129], 'present‐day': [131], 'life': [132], 'sciences': [133], 'medicine.': [136], 'Key': [137], 'Concepts': [138], 'pathways.': [142], 'labile.': [146], 'vivo': [150], 'assisted': [152], 'chaperones.': [155], 'Assisted': [156], 'requires': [159], 'ATP': [160], 'energy.': [161], 'Molecular': [162], 'evolutionary': [165], 'conserved.': [166], 'Chaperone': [167, 175], 'activity': [168], 'controlled': [170], 'co‐chaperones': [172], 'co‐factors.': [174], 'families': [176], 'differ': [177], 'structure': [179], 'function.': [181]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4239727325', 'counts_by_year': [], 'updated_date': '2025-01-26T17:25:52.396674', 'created_date': '2022-05-12'}