Publication Information

{'id': 'https://openalex.org/W4238050752', 'doi': 'https://doi.org/10.1158/1538-7445.sabcs18-4661', 'title': 'Abstract 4661: Deciphering the causes of the COSMIC mutational signature 17 by combining pan-cancer data with experimental mouse models', 'display_name': 'Abstract 4661: Deciphering the causes of the COSMIC mutational signature 17 by combining pan-cancer data with experimental mouse models', 'publication_year': 2019, 'publication_date': '2019-07-01', 'ids': {'openalex': 'https://openalex.org/W4238050752', 'doi': 'https://doi.org/10.1158/1538-7445.sabcs18-4661'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.sabcs18-4661', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S12644804', 'display_name': 'Tumor Biology', 'issn_l': '1010-4283', 'issn': ['1010-4283', '1423-0380'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'proceedings-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.1158/1538-7445.sabcs18-4661', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5083528942', 'display_name': 'Markéta Tomková', 'orcid': 'https://orcid.org/0000-0001-9094-2365'}, 'institutions': [{'id': 'https://openalex.org/I4210106789', 'display_name': 'Ludwig Cancer Research', 'ror': 'https://ror.org/01e473h50', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106789', 'https://openalex.org/I4210150094']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Marketa Tomkova', 'raw_affiliation_strings': ['Ludwig Institute for Cancer Research, University of Oxford, Oxford, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Ludwig Institute for Cancer Research, University of Oxford, Oxford, United Kingdom', 'institution_ids': ['https://openalex.org/I4210106789']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037055010', 'display_name': 'Claire Renard', 'orcid': 'https://orcid.org/0000-0001-6523-3962'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Claire Renard', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077896214', 'display_name': 'Lara Urban', 'orcid': 'https://orcid.org/0000-0002-5445-9314'}, 'institutions': [{'id': 'https://openalex.org/I1303153112', 'display_name': 'European Bioinformatics Institute', 'ror': 'https://ror.org/02catss52', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I1303153112', 'https://openalex.org/I4210138560']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Lara Urban', 'raw_affiliation_strings': ['The European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus Hinxton, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'The European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus Hinxton, United Kingdom', 'institution_ids': ['https://openalex.org/I1303153112']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001226082', 'display_name': 'Souad Kolli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Souad Kolli', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027145199', 'display_name': 'Maude Ardin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Maude Ardin', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006765959', 'display_name': 'Manuraj Pandey', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Manuraj Pandey', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034008282', 'display_name': 'Maria Zhivagui', 'orcid': 'https://orcid.org/0000-0002-3410-4014'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Maria Zhivagui', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053523685', 'display_name': 'Hana Hušková', 'orcid': 'https://orcid.org/0000-0003-3088-4081'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Hana Huskova', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027951949', 'display_name': 'Magali Olivier', 'orcid': 'https://orcid.org/0000-0002-8202-342X'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Magali Olivier', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080250007', 'display_name': 'Hiroyuki Marusawa', 'orcid': 'https://orcid.org/0000-0002-4286-2712'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroyuki Marusawa', 'raw_affiliation_strings': ['Graduate School of Medicine, Kyoto University, Kyoto, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Graduate School of Medicine, Kyoto University, Kyoto, Japan.', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030766517', 'display_name': 'Benjamin Schuster‐Böckler', 'orcid': 'https://orcid.org/0000-0002-8892-5133'}, 'institutions': [{'id': 'https://openalex.org/I4210106789', 'display_name': 'Ludwig Cancer Research', 'ror': 'https://ror.org/01e473h50', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106789', 'https://openalex.org/I4210150094']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Benjamin Schuster-Böckler', 'raw_affiliation_strings': ['Ludwig Institute for Cancer Research, University of Oxford, Oxford, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Ludwig Institute for Cancer Research, University of Oxford, Oxford, United Kingdom', 'institution_ids': ['https://openalex.org/I4210106789']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061154196', 'display_name': 'Jiří Zavadil', 'orcid': 'https://orcid.org/0000-0003-0640-5562'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jiri Zavadil', 'raw_affiliation_strings': ['Int. Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Int. Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2000, 'currency': 'USD', 'value_usd': 2000, 'provenance': 'doaj'}, 'apc_paid': {'value': 2000, 'currency': 'USD', 'value_usd': 2000, 'provenance': 'doaj'}, 'fwci': 0.086, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.391306, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 61, 'max': 69}, 'biblio': {'volume': None, 'issue': None, 'first_page': '4661', 'last_page': '4661'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11287', 'display_name': 'Cancer Genomics and Diagnostics', 'score': 0.335, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11287', 'display_name': 'Cancer Genomics and Diagnostics', 'score': 0.335, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11970', 'display_name': 'Molecular Biology Techniques and Applications', 'score': 0.287, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/signature', 'display_name': 'Signature (topology)', 'score': 0.66144425}], 'concepts': [{'id': 'https://openalex.org/C59375849', 'wikidata': 'https://www.wikidata.org/wiki/Q5013513', 'display_name': 'COSMIC cancer database', 'level': 2, 'score': 0.70747536}, {'id': 'https://openalex.org/C2779696439', 'wikidata': 'https://www.wikidata.org/wiki/Q7512811', 'display_name': 'Signature (topology)', 'level': 2, 'score': 0.66144425}, {'id': 'https://openalex.org/C111309251', 'wikidata': 'https://www.wikidata.org/wiki/Q11547', 'display_name': 'Cosmic ray', 'level': 2, 'score': 0.46968964}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.43900338}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.3873232}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.35376042}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3173645}, {'id': 'https://openalex.org/C1276947', 'wikidata': 'https://www.wikidata.org/wiki/Q333', 'display_name': 'Astronomy', 'level': 1, 'score': 0.24577364}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.12350625}, {'id': 'https://openalex.org/C2524010', 'wikidata': 'https://www.wikidata.org/wiki/Q8087', 'display_name': 'Geometry', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.sabcs18-4661', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S12644804', 'display_name': 'Tumor Biology', 'issn_l': '1010-4283', 'issn': ['1010-4283', '1423-0380'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.sabcs18-4661', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S12644804', 'display_name': 'Tumor Biology', 'issn_l': '1010-4283', 'issn': ['1010-4283', '1423-0380'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W9937313', 'https://openalex.org/W8618244', 'https://openalex.org/W79928', 'https://openalex.org/W7171036', 'https://openalex.org/W4541134', 'https://openalex.org/W4144819', 'https://openalex.org/W4092143', 'https://openalex.org/W2785975', 'https://openalex.org/W1801796', 'https://openalex.org/W11529580'], 'abstract_inverted_index': {'Gastric': [0], 'and': [1, 26, 40, 94, 114, 135, 182, 192, 201, 213, 217, 232, 238, 252, 307, 316, 339, 369, 379, 408, 412], 'esophageal': [2], 'adenocarcinomas': [3], '(G/EAC)': [4], 'exhibit': [5], 'a': [6, 27, 47, 67, 356], 'characteristic': [7], 'pattern': [8], 'of': [9, 49, 70, 98, 124, 140, 147, 175, 198, 208, 289, 355, 365, 400, 443, 460], 'somatic': [10], 'variants,': [11], 'known': [12], 'as': [13, 117, 119, 221, 269, 271], 'signature': [14, 71, 83, 109, 160, 176, 199, 229, 245, 276, 280, 314, 317, 332, 337, 347, 361, 383, 401, 447], '17.': [15, 384], 'Signature': [16, 34], '17': [17, 35, 84, 110, 161, 177, 230, 246, 277, 315, 333, 362, 448], 'associates': [18], 'with': [19, 37, 46, 165, 279, 343, 382, 403, 453], 'high': [20], 'mutation': [21], 'burden,': [22], 'elevated': [23], 'neoantigen': [24], 'levels': [25], 'potential': [28, 404], 'sensitivity': [29], 'to': [30, 77, 104, 159, 167, 258, 286, 300, 394], 'cell': [31, 127, 205], 'cycle': [32], 'inhibitors.': [33], 'correlates': [36], 'poor': [38], 'survival,': [39, 237], 'is': [41, 66, 283], 'increased': [42], 'in': [43, 86, 95, 186, 248, 260, 264, 272, 312, 319, 331, 336, 346, 363, 370], 'cancer': [44, 410], 'patients': [45], 'history': [48], 'the': [50, 106, 173, 196, 254, 292, 323, 366, 387, 396, 441, 444, 461], 'common': [51], 'pre-malignant': [52], 'lesion': [53], 'called': [54], "Barrett's": [55, 233], 'esophagus.': [56], 'We': [57, 224, 373], 'recently': [58], 'showed': [59, 340], 'that': [60, 294], 'oxidative': [61, 287, 296], 'damage': [62, 211, 288, 298], 'during': [63], 'DNA': [64, 210, 297], 'replication': [65, 180, 305, 344], 'likely': [68, 284], 'source': [69], '17;': [72], 'however': [73], 'this': [74], 'hypothesis': [75, 293], 'remains': [76], 'be': [78], 'validated.': [79], 'Intriguingly,': [80], 'we': [81, 102, 171], 'observe': [82], 'arising': [85], 'clonally': [87], 'expanded': [88], 'primary': [89, 407], 'mouse': [90, 96, 455], 'cells': [91, 191], '(Hupki': [92], 'MEF)': [93], 'models': [97, 391, 456], 'liver': [99], 'cancer.': [100], 'Here,': [101], 'aim': [103], 'identify': [105, 395], 'mechanisms': [107], 'underlying': [108, 360], 'by': [111, 449], 'mining': [112], 'TCGA': [113], 'ICGC': [115], 'data,': [116], 'well': [118, 270], 'generating': [120], 'genome-wide': [121], 'molecular': [122, 380], 'profiles': [123], 'relevant': [125, 222], 'experimental': [126, 454], 'systems.': [128, 372], 'Mutational': [129], 'signatures': [130], 'were': [131, 310], 'extracted': [132], 'from': [133, 150, 189], 'exome': [134], 'whole-genome': [136], 'sequencing': [137], '(WGS)': [138], 'data': [139, 149, 188, 243, 452], 'over': [141], '460': [142], 'G/EAC': [143, 193], 'tumors.': [144, 262], 'Pathway': [145], 'analysis': [146], 'RNA-seq': [148], 'matching': [151], 'samples': [152], 'was': [153, 162], 'performed': [154], 'using': [155, 386], 'NIH': [156], 'DAVID.': [157], 'Exposure': [158], 'next': [163], 'assessed': [164], 'regards': [166], 'clinico-pathologic': [168], 'data.': [169], 'Lastly,': [170], 'compared': [172], 'asymmetry': [174, 330], 'mutations': [178], 'around': [179], 'origins': [181], 'early/late': [183], 'replicating': [184], 'regions': [185, 251], 'WGS': [187, 242], 'MEF': [190, 241, 267, 325], 'cancers.': [194, 303], 'Comparing': [195], 'transcriptomes': [197], '17-high': [200], '-low': [202], 'tumors': [203], 'implicated': [204], 'proliferation,': [206], 'regulation': [207], 'apoptosis,': [209], 'response': [212], 'repair,': [214], 'oxidoreductase': [215], 'activity': [216, 359], 'gastric': [218], 'acid': [219], 'secretion': [220], 'pathways.': [223], 'found': [225], 'positive': [226], 'associations': [227, 381], 'between': [228], 'intensity': [231], 'esophagus': [234], 'history,': [235], 'poorer': [236], 'microsatellite': [239], 'instability.': [240], 'revealed': [244], 'enrichment': [247], 'late-replicating': [249], 'genomic': [250], 'on': [253], 'lagging': [255], 'strand,': [256], 'analogous': [257], 'observations': [259], 'human': [261, 302], 'Importantly,': [263], 'all': [265], 'cultured': [266], 'clones': [268, 326], 'most': [273], 'EAC': [274, 320], 'genomes,': [275, 321], 'co-occurred': [278], '18': [281, 318], 'which': [282], 'linked': [285], 'DNA,': [290], 'supporting': [291], 'inflammation-driven': [295], 'leads': [299], 'these': [301], 'The': [304], 'strand': [306, 329], 'timing': [308, 345], 'asymmetries': [309], 'significant': [311, 328, 341], 'both': [313], 'while': [322], 'Hupki': [324], 'exhibited': [327], 'but': [334], 'not': [335], '18,': [338], 'correlation': [342], '18.': [348], 'Collectively,': [349], 'our': [350], 'results': [351], 'elucidate': [352], 'new': [353], 'features': [354], 'modifiable': [357], 'mutagenic': [358], 'cancers': [364], 'esophagus,': [367], 'stomach,': [368], 'model': [371], 'have': [374], 'also': [375], 'identified': [376], 'novel': [377], 'clinical': [378], 'Investigations': [385], 'reported': [388], 'innovative': [389], 'cell-based': [390], 'will': [392], 'help': [393], 'precise': [397], 'mechanistic': [398], 'basis': [399], '17,': [402], 'implications': [405], 'for': [406, 464], 'secondary': [409], 'prevention': [411], 'personalized': [413], 'therapy.Citation': [414], 'Format:': [415], 'Marketa': [416], 'Tomkova,': [417], 'Claire': [418], 'Renard,': [419], 'Lara': [420], 'Urban,': [421], 'Souad': [422], 'Kolli,': [423], 'Maude': [424], 'Ardin,': [425], 'Manuraj': [426], 'Pandey,': [427], 'Maria': [428], 'Zhivagui,': [429], 'Hana': [430], 'Huskova,': [431], 'Magali': [432], 'Olivier,': [433], 'Hiroyuki': [434], 'Marusawa,': [435], 'Benjamin': [436], 'Schuster-Böckler,': [437], 'Jiri': [438], 'Zavadil.': [439], 'Deciphering': [440], 'causes': [442], 'COSMIC': [445], 'mutational': [446], 'combining': [450], 'pan-cancer': [451], '[abstract].': [457], 'In:': [458], 'Proceedings': [459], 'American': [462], 'Association': [463], 'Cancer': [465, 479], 'Research': [466], 'Annual': [467], 'Meeting': [468], '2019;': [469], '2019': [470], 'Mar': [471], '29-Apr': [472], '3;': [473], 'Atlanta,': [474], 'GA.': [475], 'Philadelphia': [476], '(PA):': [477], 'AACR;': [478], 'Res': [480], '2019;79(13': [481], 'Suppl):Abstract': [482], 'nr': [483], '4661.': [484]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4238050752', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}], 'updated_date': '2024-12-24T04:49:04.459537', 'created_date': '2022-05-12'}