Title: Insecticidal activity of some 3, 5-pyrazolidinedione derivatives against cotton leaf worm, Spodoptera littoralis (Boised) (Lepidoptera: Noctuidae)
Abstract:Four 3,5-pyrazolidinedione derivatives namely, 4-(4`-chlorobenzylidene)-1-phenylpyrazolidine-3,5-dione (1), 4-(4`-nitrobenzylidene)-1-phenylpyrazolidine-3,5-dione (2), 2'-(4-chlorophenyl)-1phenyl-3,5-...Four 3,5-pyrazolidinedione derivatives namely, 4-(4`-chlorobenzylidene)-1-phenylpyrazolidine-3,5-dione (1), 4-(4`-nitrobenzylidene)-1-phenylpyrazolidine-3,5-dione (2), 2'-(4-chlorophenyl)-1phenyl-3,5-dioxo-1,2,3,5 tetrahydrospiropyrazole-4,3' oxirane (3) and 2'-(4-nitrophenyl)-1phenyl-3,5-dioxo-1,2,3,5 tetrahydrospiropyrazole-4,3' oxirane (4) were prepared in pure state and bioassayed against 2 nd and 4 th instars larvae of cotton leaf worm, Spodoptera littoralis (Boised) (Lepidoptera: Noctuidae) using feeding and dipping bioassay.The results of bioassays indicated that title compounds exhibit satisfactory insecticidal activities.Among those, compound (1) exhibit the highest insecticidal activities against 2 nd instar larvae, with LC 50s 3.23 and 0.619 mgL -1 for feeding, and 36.04 and 28.69 mgL -1 for dipping, after 48 and 72 h treatment.According to the toxicity index the compound (1) showed the highest larvicidal activity against 4 th instar larvae with LC 50s 141.33 and 76.12 mgL -1 for feeding larvae, and 26.94 and 12.29 mgL -1 for dipping larvae after 48 and 72 h treatment.These results showed that, the 2 nd larvae was more susceptible than 4 th instars larvae to these compounds.In addition, the insecticidal activity of these compounds was Aly A. Abd-Ella et al. 2 more effective on cotton leaf worm larvae in feeding bioassay as compared with the dipping treatment.The rest of the tested compounds possessed moderate to strong larvicidal activities against cotton leaf worm.In general, the results indicate the possible use of 3,5-pyrazolidinedione derivatives as components in integrated pest management program against S. littoralis.Read More