Title: Intermediate and Long-term Outcomes of Giant Fibroadenoma Excision in Adolescent and Young Adult Patients
Abstract: The Breast JournalVolume 21, Issue 3 p. 254-259 Original Article Intermediate and Long-term Outcomes of Giant Fibroadenoma Excision in Adolescent and Young Adult Patients Felecia E. Cerrato MPH, Felecia E. Cerrato MPH Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorSandhya Pruthi MD, Sandhya Pruthi MD Breast Clinic, Mayo Clinic, Rochester, Minnesota Division of General Internal Medicine, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorJudy C. Boughey MD, Judy C. Boughey MD Department of Surgery, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorPatricia S. Simmons MD, Patricia S. Simmons MD Breast Clinic, Mayo Clinic, Rochester, Minnesota Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorBarbara Salje MBChB, Barbara Salje MBChB Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorLaura C. Nuzzi BA, Laura C. Nuzzi BA Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorValerie Lemaine MD, MPH, Valerie Lemaine MD, MPH Division of Plastic Surgery, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorBrian I. Labow MD, Corresponding Author Brian I. Labow MD Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsAddress correspondence and reprint requests to: Brian I. Labow, MD, FACS, FAAP, Department of Plastic and Oral Surgery, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Hunnewell- 1, Boston, MA 02115, USA, or e-mail: [email protected]Search for more papers by this author Felecia E. Cerrato MPH, Felecia E. Cerrato MPH Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorSandhya Pruthi MD, Sandhya Pruthi MD Breast Clinic, Mayo Clinic, Rochester, Minnesota Division of General Internal Medicine, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorJudy C. Boughey MD, Judy C. Boughey MD Department of Surgery, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorPatricia S. Simmons MD, Patricia S. Simmons MD Breast Clinic, Mayo Clinic, Rochester, Minnesota Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorBarbara Salje MBChB, Barbara Salje MBChB Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorLaura C. Nuzzi BA, Laura C. Nuzzi BA Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorValerie Lemaine MD, MPH, Valerie Lemaine MD, MPH Division of Plastic Surgery, Mayo Clinic, Rochester, MinnesotaSearch for more papers by this authorBrian I. Labow MD, Corresponding Author Brian I. Labow MD Department of Plastic and Oral Surgery and Adolescent Breast Clinic, Boston Children's Hospital and Harvard Medical School, Boston, MassachusettsAddress correspondence and reprint requests to: Brian I. Labow, MD, FACS, FAAP, Department of Plastic and Oral Surgery, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Hunnewell- 1, Boston, MA 02115, USA, or e-mail: [email protected]Search for more papers by this author First published: 13 March 2015 https://doi.org/10.1111/tbj.12394Citations: 5Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Giant fibroadenomas (5 cm or greater) are benign breast masses that often present in adolescence and require surgical excision. Long-term outcomes, recurrence rates, and the need for additional reconstructive surgery in this population are unknown. Patients aged 11–25 years whose pathology reports indicated the presence of a giant fibroadenoma were eligible for this study. Medical records were reviewed for presentation, treatment, and outcomes. A subset of patients completed an investigator-designed long-term outcome survey to measure additional outcomes and the desire or need for subsequent reconstructive surgery. Forty-six patients with at least one giant fibroadenoma (mean size 7.4 ± 2.8 cm) were identified. Most patients underwent excision with a periaroeolar incision (n = 31), and an enucleation technique (n = 41), and four patients underwent immediate breast reconstruction. Thirty-three patients had complete medical records with a mean follow-up time of 2.2 ± 4.1 years and no complaints of asymmetry, additional breast deformities, or reconstructive surgery procedures documented. In addition, nine patients completed the investigator-designed survey with a mean follow-up time of 10.1 ± 8.7 years (range 1.5–27.0). Three of these patients reported postoperative breast asymmetry and the desire to pursue reconstructive surgery. Aesthetic outcomes of giant fibroadenoma excision may be satisfactory for many patients without immediate reconstruction, but for others, the need for reconstructive surgery may arise during development. Providers should address this potential need prior to discussing treatment options and during postoperative follow-up. Caution should be exercised before recommending immediate reconstruction. References 1Greenberg R, Skornick Y, Kaplan O. Management of breast fibroadenomas. J Gen Intern Med 1998; 13: 640– 5. 2Neinstein LS, Atkinson J, Diament M. Prevalence and longitudinal study of breast masses in adolescents. J Adolesc Health 1993; 14: 277– 81. 3Simmons PS, Wold LE. 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