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'onFacebookTwitterLinkedInRedditWechat': [444], 'Abstract': [445], 'The': [446, 520, 685], 'tumor': [447, 686, 710, 715, 784, 901], 'suppressor': [448, 687, 1177], 'p53': [449, 505, 587, 607, 713, 783, 1028, 1061, 1178, 1242, 1317, 1339, 1352, 1398, 1428], 'plays': [450], 'central': [452], 'role': [453], 'negative': [455], 'growth': [456, 459, 939, 1127], 'control,': [457], 'including': [458, 474], 'arrest': [460, 940, 1347], 'apoptosis.': [462, 475, 519, 942, 1279, 1404], 'Interferons': [463, 670], '(IFNs)': [464], 'are': [465, 1128], 'capable': [466], 'modulating': [468], 'variety': [470], 'cellular': [472, 583], 'responses,': [473], 'In': [476], 'study,': [478], 'we': [479], 'evaluated': [481], 'influence': [483], 'γ-': [485], 'α-interferon': [487], '(IFN)': [488], 'on': [489, 898, 1116], 'wild-type': [490, 1338], '(wt)': [491], 'using': [494], 'line,': [499], 'BL41,': [500], 'transfected': [501], 'temperature-sensitive': [504, 1093], 'construct.': [506], 'γ-IFN,': [507], 'but': [508], 'not': [509, 561], 'α-IFN,': [510], 'was': [511, 523, 560], 'found': [512], 'protect': [514], 'cells': [515, 999, 1160, 1276, 1433], 'from': [516, 1000, 1277], 'wt': [517, 586], 'γ-IFN-dependent': [521], 'protection': [522], 'due': [524], 'neither': [525], 'down-regulation': [527], 'p53,': [529], 'nor': [530, 539], 'genes,': [534], 'p21': [535], '(WAF-I)': [536], 'bax,': [538], 'up-regulation': [541], 'bcl-2': [543, 994, 1380], 'or': [544], 'bcl-xL.': [545], 'Expression': [546], 'proto-oncogene': [549], 'c-myc,': [550], 'implicated': [551], 'control': [554, 611], 'both': [556], 'proliferation': [557, 1090], 'apoptosis,': [559, 572], 'affected': [562], 'γ-IFN.': [564], 'We': [565], 'conclude': [566], 'that': [567, 574, 1252, 1434], 'γ-IFN': [568], 'can': [569], 'suppress': [570], 'cytokine': [576], 'microenvironment': [577], 'may': [578], 'be': [579], 'decisive': [580], 'response': [584], 'expression.': [588], '©': [589], 'Wiley-Liss,': [591], 'Inc.': [592], 'References': [593], 'Aloni-Grinstein,': [594], 'R.,': [595, 764, 1291], 'Zan-Bar,': [596], 'I.,': [597, 599, 793, 1367], 'Alboum,': [598], 'Goldfinger,': [600], 'N.': [601], 'Rotter,': [603], 'V.,': [604], 'Wild': [605], 'type': [606], 'functions': [608], 'as': [609, 649], 'protein': [612, 648, 1208], 'differentiation': [615, 718], 'pathway': [616], 'B-cell': [619, 1302], 'lineage.': [620], 'Oncogene,': [621, 1165, 1256, 1280, 1387], '8,': [622, 970, 1166, 1257, 1358, 1388], '3297–': [623], '3305': [624], '(1993).': [625, 695, 751, 790, 913, 1075, 1169, 1260, 1391], 'Deiss,': [626], 'L.': [627, 680, 811, 1203], 'P.,': [628, 976, 979, 1230], 'Feinsten,': [629], 'E.,': [630, 699, 759, 771, 867, 1104, 1144, 1415], 'Berissi,': [631], 'H.,': [632, 736, 796, 804, 991], 'Cohen,': [633], 'O.': [634, 1079], 'Kimchi,': [636, 1422], 'A.,': [637, 684, 837, 922, 924, 930, 1148, 1195, 1328], 'Identification': [638, 838], 'novel': [641, 646], 'serine/threonine': [642], 'kinase': [643], '15-kD': [647], 'potential': [650, 780], 'mediators': [651], 'γ-interferon-induced': [654], 'death.': [656], 'Genes': [657, 1356], 'Devel.,': [658, 1357], '9,': [659, 1222], '15–': [660], '30': [661], '(1995).': [662, 731, 947, 1141, 1193, 1225, 1284], 'De': [663, 667, 920], 'Mayer,': [664], 'E.': [665, 1050], 'Mayer-Guignard,': [668], 'J.,': [669, 1016, 1266, 1397, 1419], 'other': [672], 'regulatory': [673], 'cytokines.': [674], 'Wiley,': [675], 'New': [676], 'York': [677], '(1988).': [678], 'Donehower,': [679], 'A.': [681, 795, 975, 990, 1057, 1103, 1108, 1143, 1262, 1396, 1423], 'Bradley,': [683], 'p53.': [688, 1096, 1255], 'Biochem.': [689], 'biophys.': [690], 'Acta,': [691], '1155,': [692], '181–': [693], '205': [694], 'Ehinger,': [696], 'M.,': [697, 767, 806, 809, 919, 949, 982, 1051, 1082, 1426], 'Nilsson,': [698], 'Persson,': [700], 'A.-M.,': [701], 'Olsson,': [702], 'I.': [703, 1265], 'Gullberg,': [705], 'U.,': [706], 'Involvement': [707], 'supressor': [711], 'gene': [712], 'necrosis': [716], 'factor-induced': [717], 'leukemic': [721, 1301], 'K562.': [724], 'Cell': [725, 853, 1305], 'Growth': [726], 'Differ.,': [727], '6,': [728], '9–': [729], '17': [730], 'S.': [733, 836, 1015, 1047, 1053], 'Sbtrander,': [735], 'Interferon': [737, 963], 'treatment': [738], 'human': [740, 1117, 1186, 1212, 1300], 'malignancies—a': [741], 'short': [742], 'review.': [743], 'Med.': [744], 'Oncol.': [745], 'Pharmacother.,': [747], '10,': [748], '25–': [749], '29': [750], 'El-Deiry,': [752], 'W.': [753, 774, 1021], 'S.,': [754, 799, 872, 893, 962, 1019, 1199], 'Tokino,': [755], 'T.,': [756, 1060, 1227], 'Velculescu,': [757], 'V.': [758, 1022], 'Levy,': [760], 'D.': [761, 815, 929, 1288], 'B.,': [762, 777, 955, 1026], 'Parsons,': [763], 'Trent,': [765], 'J.': [766, 852, 908, 1008, 1107, 1136, 1147, 1174, 1327, 1330], 'Lin,': [768], 'D.,': [769, 802, 860, 888, 951, 1077, 1112, 1155, 1417], 'Mercer,': [770], 'Kinzler,': [772, 1314], 'K.': [773, 984, 1229, 1239, 1315, 1372], 'Vogelstein,': [776, 1311], 'WAF1,': [778], 'mediator': [781], 'suppression.': [785], 'Cell,': [786, 825, 1097, 1189, 1321], '75,': [787], '817–': [788], '825': [789], 'Evan,': [791], 'Wyllie,': [794], 'Gilbert,': [797], 'C.': [798, 808, 978, 1111, 1150, 1154], 'Littlewood,': [800], 'T.': [801, 1171], 'Land,': [803], 'Brooks,': [805], 'Wters,': [807], 'Penn,': [810], 'Z.': [812], 'Hancock,': [814], 'C.,': [816, 915, 1175], 'Induction': [817], 'fibroblasts': [821], 'c-myc': [823], 'protein.': [824], '69,': [826], '119–': [827], '128': [828], '(1992).': [829, 858, 1045, 1325], 'Gavrieli,': [830], 'Y.,': [831, 957, 1232, 1363], 'Sherman,': [832], 'Y.': [833], 'Ben-Sasson,': [835], 'programmed': [840, 1295], 'death': [842, 1297], 'situ': [844], 'via': [845], 'specific': [846], 'labelling': [847], 'nuclear': [849], 'DNA': [850], 'fragmentation.': [851], 'Biol.,': [854], '119,': [855], '493–': [856], '501': [857], 'Öberg,': [861], 'K.,': [862, 953, 1197, 1201], 'Lundqvist,': [863], 'M.-L,': [864], 'Tiensuu': [865], 'Jansson,': [866], 'Eriksson,': [868], 'B.': [869, 890, 926, 959, 1018, 1056, 1312], 'Interferon-induced': [873], 'enhancement': [874], '2′,5′-oligoadenylate': [876], 'synthetase': [877], 'mid-gut': [879], 'carcinoid': [880], 'tumours.': [881], 'Lancet,': [882], '336,': [883], '337–': [884], '340': [885], '(1990).': [886, 1101], 'Xu,': [889, 958], 'Cytotoxic': [894], 'effect': [895], 'primary': [899], 'malignant': [900, 967], 'cells.': [902], 'Studies': [903], 'various': [905], 'malignancies.': [906], 'Europ.': [907], 'Cancer,': [909, 1137], '14,': [910], '1940–': [911], '1943': [912], 'Guillouf,': [914], 'Xavier,': [916], 'G.,': [917, 1206, 1240, 1373], 'Selvakumaran,': [918], 'Luca,': [921], 'Giordano,': [923], 'Hoffman,': [925], 'Liebermann,': [928], 'Dissection': [931], 'genetic': [934], 'programs': [935], 'p53-mediated': [937, 1278], 'G1': [938], 'Blood,': [943], '85,': [944], '2691–': [945], '2698': [946], 'Heyman,': [948], 'Bröndum-Nielsen,': [952], 'Cederblad,': [954], 'Liu,': [956], 'system': [964], 'defects': [965], 'T-cells.': [968], 'Leukemia,': [969, 1221], '425–': [971], '434': [972], '(1994).': [973, 1013, 1310, 1361, 1413], 'Jewell,': [974], 'Worman,': [977], 'Lydyard,': [980], 'P.': [981], 'Yong,': [983], 'L.,': [985, 1234, 1365, 1421], 'Giles,': [986], 'Fj.': [987], 'Goldstone,': [989], 'Interferon-alpha': [992], 'up-regulates': [993], 'expression': [995, 1209], 'protects': [997, 1274], 'B-CLL': [998], 'vitro': [1003], 'vivo.': [1006], 'Brit.': [1007], 'Haematol.,': [1009], '88,': [1010], '268–': [1011], '274': [1012], 'Kuerbitz,': [1014], 'Plunkett,': [1017], 'Walsh,': [1020], 'Kastan,': [1024], 'M.': [1025, 1151, 1271, 1331], 'cycle': [1032, 1346], 'checkpoint': [1033], 'determinant': [1034], 'following': [1035], 'irradiation.': [1036], 'Proc.': [1037, 1405], 'nat.': [1038, 1406], 'Acad.': [1039, 1407], 'Sci.,': [1040], '(Wash.),': [1041, 1409], '89,': [1042], '7491–': [1043], '7495': [1044], 'Lowe,': [1046], 'W.,': [1048, 1054, 1316], 'Schmitt,': [1049], 'Smith,': [1052], 'Osborne,': [1055], 'Jacks,': [1059], 'required': [1063], 'radiation-induced': [1065], 'mouse': [1068], 'thymocytes.': [1069], 'Nature': [1070, 1439], '(Lond.),': [1071, 1440], '362,': [1072], '847–': [1073], '849': [1074], 'Michalovitz,': [1076], 'Halevy,': [1078], 'Oren,': [1081, 1425], 'Conditional': [1083], 'inhibition': [1084], 'transformation': [1086], 'mutant': [1094, 1254], '62,': [1098], '671–': [1099], '680': [1100], 'Milner,': [1102, 1142], 'Grand,': [1105, 1145], 'R.': [1106, 1146], 'Gregory,': [1110, 1153], 'Effects': [1113], 'interferon-α': [1115], 'B': [1118], 'cells:': [1119], 'repression': [1120], 'prevention': [1124], 'independent': [1129, 1343], 'responses': [1130], 'lines.': [1134, 1303], 'Int.': [1135], '61,': [1138], '348–': [1139], '354': [1140], 'Waters,': [1149], 'Apoptosis': [1156], 'driven': [1162], 'c-myc.': [1164], '3385–': [1167], '3391': [1168], 'Miyashita,': [1170], 'Reed,': [1173], 'direct': [1181], 'transcriptional': [1182], 'activator': [1183], 'bax': [1187], 'gene.': [1188], '80,': [1190], '293–': [1191], '299': [1192], 'Porwit-Macdonald,': [1194], 'Ivory,': [1196], 'Wilkinson,': [1198], 'Wheatley,': [1200], 'Wong,': [1202], 'Janossy,': [1205], 'Bcl-2': [1207], 'normal': [1211], 'bone': [1213], 'marrow': [1214], 'precursors': [1215], 'acute': [1218], 'myelogenous': [1219], 'leukemia.': [1220], '1191–': [1223], '1198': [1224], 'Ramqvist,': [1226], 'Magnusson,': [1228], 'Wang,': [1231, 1362], 'Szekely,': [1233, 1364], 'Klein,': [1235, 1368], 'induces': [1243, 1294, 1429], '(BL)': [1249], 'carries': [1253], '1495–': [1258], '1500': [1259], 'Schott,': [1261], 'F.,': [1263, 1272], 'Apel,': [1264], 'Nunez,': [1267], 'Clarke,': [1270], 'Bcl-xL': [1273], 'cancer': [1275], '11,': [1281], '1389–': [1282], '1394': [1283], 'Trubiani,': [1285], 'O.,': [1286], 'Bosco,': [1287], 'Di-Primio,': [1290], 'Interferon-gamma': [1292], '(IFN-gamma)': [1293], 'differentiated': [1299], 'Exp.': [1304], 'Res.,': [1306], '215,': [1307], '23–': [1308], '27': [1309], 'function': [1318], 'dysfunction.': [1320], '70,': [1322], '523–': [1323], '526': [1324], 'Wagner,': [1326], 'Kokontis,': [1329], 'Hay,': [1333], 'N.,': [1334], 'Myc-mediated': [1335], 'requires': [1337], 'manner': [1342], 'ability': [1350], 'induce': [1354], 'p21wafl/cipl.': [1355], '2817–': [1359], '2830': [1360], 'p53-triggered': [1375], 'v-myc-induced': [1383], 'T-cell': [1384], 'line.': [1386], '3427–': [1389], '3431': [1390], 'Wu,': [1392], 'X.': [1393], 'Levine,': [1395], 'E2F-1': [1400], 'cooperate': [1401], 'mediate': [1403], 'Sci.': [1408], '91,': [1410], '3602–': [1411], '3606': [1412], 'Yonish-Rouach,': [1414], 'Resnitzky,': [1416], 'Lotem,': [1418], 'Sachs,': [1420], 'myeloid': [1432], 'interleukin-6.': [1438], '352,': [1441], '345–': [1442], '347': [1443], '(1991).': [1444], 'Citing': [1445], 'Literature': [1446], 'Volume67,': [1447], 'Issue13': [1448], '1996Pages': [1450], 'ReferencesRelatedInformation': [1452]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4235082743', 'counts_by_year': [], 'updated_date': '2024-09-19T17:08:12.821158', 'created_date': '2022-05-12'}