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'technique,': [267, 2575, 2621], 'TI': [270, 890, 1028, 1054, 1129, 1156, 1285, 1383, 1423, 1430, 1452, 1581, 1608, 1619, 1679, 2007, 2075, 2416, 2449, 2524], 'between': [271, 617, 779, 1233, 2236, 2951], 'application': [273, 723, 2322, 3155], 'tag': [276, 562, 610, 618, 673, 727, 731, 754, 762, 780, 802, 882, 902, 1222, 1235, 2121, 2237, 2623, 2631, 2661, 2671], 'image': [278, 456, 674, 1092, 1244, 1863, 2445, 2484], 'acquisition': [279, 457, 670, 678, 899, 989, 1093, 2438, 2446, 2477, 2485], 'longer': [281, 489, 843, 915, 1058, 1477, 2345], 'repetition': [284], 'TR,': [286, 592, 1369], 'allowing': [287], 'use': [290, 376, 434, 448, 956, 2006, 2158, 2529], 'greatly': [292, 460, 1095], 'reduced': [293, 394, 507, 1831], 'TR': [294, 650, 688, 826, 846, 910, 931, 959, 1292, 1377, 1436, 1587, 1636, 1651, 1657, 1664, 1676, 1706, 1730, 2009, 2022, 2053, 2064, 2073, 2085, 2341, 2346, 2455, 2704], 'values': [295, 824, 957, 1455, 2023, 2522, 3216], 'without': [296, 832, 1481, 1531, 2402], 'significant': [298, 1532, 2920], 'decrease': [299, 834, 1988], 'amplitude': [302], 'signal.': [306, 838, 1502, 2041], 'This': [307, 581, 684, 820, 1414, 1843, 2138, 2275], 'improves': [308, 461, 518], 'sensitivity': [315, 1847, 1928, 2750, 2853], 'functional': [319, 365, 417, 1389, 1763, 1788, 1828, 1854, 2226, 2749, 3116, 3157, 3181], 'brain': [320, 383, 424, 438, 1605, 1696, 2385, 2888, 3036, 3060, 3158, 3182, 3250], 'mapping.': [321, 3251], 'Magn': [322, 2807, 2839, 2893, 2929, 3000, 3160, 3224, 3275], 'Reson': [323, 2808, 2840, 2894, 2930, 3001, 3161, 3225, 3276], 'Med': [324, 2809, 2841, 2895, 2931, 3002, 3162, 3226, 3277], '44:511–515,': [325], '2000.': [326, 3081], '©': [327], 'Wiley-Liss,': [329], 'Inc.': [330], 'techniques': [335, 2730, 3179], 'are': [336, 389, 594, 606, 830, 961, 1003, 1066, 1325, 1443, 1469, 1556, 1630, 2025, 2057, 2098, 2152, 2245, 2418, 2544, 2600], 'becoming': [337], 'well': [338, 2140, 2382], 'established': [339], 'as': [340, 548, 609, 967, 1104, 1632, 1715, 1726, 1864, 2171, 2190, 2201, 2577], 'efficient': [341], 'methods': [342], 'measurement': [344], 'cerebral': [346, 2861, 2952, 2990, 3028, 3112, 3213], 'blood': [347, 405, 564, 574, 640, 662, 707, 715, 746, 863, 875, 979, 1274, 1485, 1955, 2168, 2177, 2200, 2470, 2696, 2862, 2882, 2953, 2991, 3029, 3113, 3214], 'flow': [348, 1482, 1504, 1583, 2532, 2883, 2954, 2992, 3032, 3114, 3215], '(CBF)': [349], '(1-3).': [350], 'While': [351, 1698, 1791, 1910, 2562], 'been': [354], 'used': [355, 560, 1130, 1136, 1530, 2034, 2255, 2557, 2744], 'extensively': [356], 'dynamic': [358], 'CBF': [359, 1857, 2376, 2916, 3269], 'measurements': [360], 'study': [363], 'MRI': [366], '(fMRI)': [367], 'contrast': [368, 395], 'mechanisms': [369], '(4-8),': [370], 'it': [371, 2147, 2172, 2202, 2334], 'not': [373, 598, 766, 981, 1983, 2001, 2099, 2407, 2472, 2636], 'found': [374], 'widespread': [375], 'fMRI': [378, 2716, 3057], 'itself,': [379], 'i.e.,': [380], 'mapping': [381, 439, 3110, 3183], 'function.': [384], 'The': [385, 615, 939, 994, 1007, 1031, 1607, 1729, 1771, 1815, 1886, 1994, 2067, 2321, 2483, 2597], 'reasons': [386], 'probably': [390], 'several-fold,': [391], 'include': [393], 'noise': [397], 'ratio': [398], '(CNR)': [399], 'relative': [403, 531, 2913], 'oxygenation': [406, 2885, 3030], 'level-dependent': [407], '(BOLD)': [408], 'However,': [410], 'there': [411, 850, 1699, 2151], 'now': [413], 'evidence': [414], 'signal': [419, 429, 464, 624, 632, 1074, 1316, 1350, 1459, 1539, 1568, 1579, 1598, 1629, 1646, 1674, 1690, 1749, 1795, 1808, 1852, 1875, 1913, 1920, 2080, 2221, 2394, 2565, 2582, 2987, 3058, 3123], 'better': [421, 3062], 'localized': [422], 'parenchyma': [425], 'BOLD': [428, 479, 493, 2581, 2598, 2918, 2986], '(9,': [430], '10),': [431], 'therefore': [441, 1926], 'current': [443], 'interest.': [444], 'addition,': [446, 1298], 'short': [450, 2087, 2572, 2664], 'echo': [451, 469, 490, 1201, 2590, 2594], '(TE)': [453], 'spirals': [454, 477], 'over': [465, 1460, 1602, 1652, 1694, 1750, 1876], 'common': [468], 'planar': [470, 2391], '(EPI)-based': [471], 'implementations,': [472, 534], 'while': [473, 535, 1018, 2682], 'advantage': [475, 1945], 'imaging': [480, 577, 666, 866, 879, 926, 985, 1239, 1278, 1332, 1346, 1491, 2194, 2267, 2319, 2377, 2392, 2574, 2779, 2796, 2834, 2858, 3121, 3146, 3178], 'less': [482], 'dramatic': [483], 'because': [484, 849, 2165, 2333], 'requirement': [487], 'times': [491], 'weighting.': [494], 'We': [495, 542, 2708, 2769], 'address': [496], 'remaining': [499], 'deficiency': [500], 'fMRI,': [504], 'resolution,': [509], 'introducing': [511], 'modification': [513, 1939, 2276], 'at': [525, 588, 886, 893, 1276, 1294, 1385, 2131, 2721], 'least': [526, 894, 2722], 'factor': [528], 'two': [530, 654, 1009, 2126], 'conventional': [533, 1081, 1419, 1727, 1766, 1839, 1867, 1879, 2728], 'preserving': [536], 'image.': [541, 683, 903, 993, 1993, 2482, 2739], 'refer': [543], 'turbo': [549, 1001, 1024, 1035, 1120, 1440, 1500, 1537, 1716, 1769, 1800, 1819, 1850, 1883, 1908, 1917, 1973, 2248, 2261, 2370, 2431, 2783], 'ASL.': [550, 1159, 1868, 1968, 2249], 'THEORY': [551, 2096], 'techniques,': [555, 647], 'an': [556, 601, 800, 887, 953, 1051, 1497, 1751, 2278], 'RF': [557, 2642, 2650, 2680], 'pulse': [558, 1032, 1122, 2281, 2326], 'magnetic': [566, 2856], 'inversion,': [567, 2628], 'delivery': [570, 860, 921, 1952], 'tagged': [573, 698, 709, 862, 874, 923, 977, 1273, 1318, 1484, 1954, 2167, 2176, 2199, 2469, 2511, 2540], 'region': [578, 667, 702, 743, 755, 1236, 1465, 2286, 2316, 2338, 2356, 2672], 'observed.': [580], 'usually': [583, 2030, 2663], 'accomplished': [584], 'collecting': [586], 'images': [587, 621, 1247, 1442, 2599, 2613], 'regular': [589], 'intervals,': [591], 'which': [593, 704, 1027, 1394, 1823, 2146, 2782], 'alternately': [595, 2601], 'preceded': [596, 599], 'inversion': [603, 888, 1052, 1210, 1785, 3151], 'tag.': [604], 'These': [605, 1323, 1640, 2542], 'referred': [607, 1713, 1724], 'control': [612, 620, 682, 771, 992, 1213, 1283, 2123, 2239, 2288, 2481], 'images,': [613, 763, 772, 1624], 'respectively.': [614], 'difference': [616], 'removes': [622], 'contribution': [625, 1534], 'from': [626, 1134, 1288, 1317, 1351, 1379, 1540, 1553, 1757, 1835, 2313, 2489, 2677, 2915], 'static': [627], 'tissues': [628, 2187, 3061], 'gives': [630, 1496, 1507, 1512], 'proportional': [635], 'amount': [638], 'delivered': [641], 'tissue.': [644], 'these': [646, 1011, 1352, 2243], 'minimum': [649, 973], 'limited': [652, 2635], 'considerations.': [655], 'First,': [656, 2164], 'bolus': [658], 'inverted': [660, 757], 'must': [663, 710, 883, 2005, 2462], 'enter': [664], 'before': [668, 721, 898, 987, 1269, 1304, 2476], 'after': [676], 'previous': [681], 'requires': [685, 775, 2218], 'be': [689, 711, 811, 884, 914, 998, 1339, 1529, 2033, 2254, 2349, 2357, 2366, 2373, 2452, 2487, 2556, 2584, 2706, 2743], 'greater': [690, 785, 2453], 'width': [694, 734], 'τ': [695, 809, 897], 'bolus.': [699], 'Second,': [700, 2196], 'refreshed': [712], 'relaxed': [714, 745, 2360, 2695], 'inflow': [717, 748, 2676], 'and/or': [718], 'T1': [719, 2687], 'relaxation': [720, 2688], 'next': [726], 'pulse.': [728, 2655], 'For': [729, 799, 1241, 1433, 1475, 1616, 2618, 2656], 'τ,': [735, 787], 'required': [738, 2350], 'refresh': [740], 'tagging': [742, 1218, 2285, 2315, 2337, 2355, 2699, 3222], 'also': [750, 1470, 2555], 'τ.': [751], 'Because': [752, 1088, 2362], 'preparation': [759, 2144], 'perturbed': [767], 'prior': [768], 'only': [774, 1022, 1833, 2083, 2691, 2732], 'pulses': [781], '(2': [782], 'TR)': [783], 'condition': [789], 'automatically': [792], 'satisfied': [793], 'first': [796, 1008], 'consideration': [797], 'above.': [798], '10': [804, 1225, 3084], 'cm': [805, 1193, 1226, 1232], 'length,': [806], 'we': [807, 2368], 'measured': [808, 3217], 'range': [814, 829, 853, 1358, 1450, 1655, 2519], '700–800': [816], 'ms': [817, 948, 1381, 1480, 1527, 1622, 2056], '(1,': [818, 936], '2).': [819], 'would': [821, 2327, 2347], 'suggest': [822], 'possible': [831, 1705, 2521], 'practice,': [840], 'somewhat': [842], 'value': [844, 974, 1256, 1266, 1520], 'necessary': [848], 'transit': [855, 943, 1948, 2311], 'delays': [856, 2312], 'δt': [857, 895, 945], 'slice(s).': [867], 'order': [869, 1261, 1312, 1362, 1957, 2011, 2231, 2352], 'all': [871, 927, 2466], 'reach': [877, 2473], 'slice,': [880, 1333, 2175, 2208], 'applied': [885, 2282, 2625], '+': [896], 'typical': [905], 'implementations': [906], 'ASL,': [909, 1025, 2018], 'chosen': [912, 1774], 'TI,': [917], 'tag,': [920, 2294], 'blood,': [924], 'occur': [928], 'within': [929, 1493], 'one': [930, 2004, 2461], 'period': [932, 2342], '2–4': [934], 'sec': [935, 1901, 1906], '11,': [937], '12).': [938], 'presence': [940], 'delay': [944, 1949], '(typically': [946], '300–1000': [947], '(1-3,': [949], '13,': [950], '14))': [951], 'provides': [952], 'opportunity': [954], 'shorter': [962, 2027], 'TI.': [964, 1087, 2066], 'As': [965, 2513], 'long': [966], 'TI-TR': [968, 1476, 1494, 1522, 1560], 'smaller': [970], 'δt,': [976], 'will': [980], 'arrive': [982, 1329], 'slice': [986, 1199, 1492, 2183, 2441, 2475, 2499], 'conditions': [995, 1063, 2091, 2124], 'should': [997, 2486], 'met': [999], 'thus': [1004, 1964, 2634, 2742], 'summarized': [1005], 'by:': [1006], 'apply': [1012], 'general,': [1017], 'third': [1020, 1780], 'applies': [1021, 1610, 1732], '>': [1029, 2008, 2054, 2065], 'TR.': [1030, 1060], 'sequence': [1033, 1049, 2780], 'shown': [1038, 1444, 1631], 'schematically': [1039], 'Fig.': [1041, 1446, 1638, 1804, 2043, 2516], '1,': [1042], 'basic': [1046], 'slightly': [1057, 1797], 'If': [1061, 2448], 'described': [1064, 1142], 'above': [1065, 2093], 'met,': [1067], 'then': [1068, 2136, 2348, 2460], 'magnitude': [1070], 'identical': [1076], 'same': [1086, 1861, 1891, 2748, 2765], 'rate': [1090, 1962, 2925], 'increased,': [1096, 1103], 'technique.': [1111], 'Figure': [1112, 1573, 1668, 1738, 1869], '1Open': [1113], 'figure': [1115, 1576, 1671, 1872], 'viewerPowerPoint': [1116, 1577, 1672, 1873], 'Schematic': [1117], 'diagram': [1118], 'sequence.': [1123, 2596], 'Note': [1124], 'definition': [1127, 1154], 'different': [1133], 'abstract': [1139], 'initially': [1141], '(15),': [1145], 'keeping': [1150], 'usual': [1153, 2061], 'METHODS': [1160], 'was': [1163, 1180, 1286, 1302, 1374, 1391, 1416, 1773, 2148, 2785], 'implemented': [1164], 'on': [1165, 2989], '1.5': [1167], 'T': [1168], 'GE': [1169], 'Signa': [1170], 'LX': [1171], 'Echospeed': [1172], 'system': [1173], 'using': [1174, 1182, 1418, 1778, 2270, 2396, 2570, 2587, 2717, 2799, 3184, 3219], 'standard': [1176], 'birdcage': [1177], 'headcoil.': [1178], 'Imaging': [1179], 'performed': [1181, 1392, 1398], 'single': [1184, 2272, 2801], 'shot': [1185], 'spiral': [1186, 1306, 2595, 2778], 'readout': [1187, 1307], 'following': [1190], 'parameters:': [1191], '24': [1192], 'field': [1194], 'view,': [1196], '8': [1197, 3007], 'mm': [1198], 'thickness,': [1200], '3–10': [1203], 'ms,': [1204, 1290, 1439, 1564], '64': [1205, 1207], '×': [1206], 'matrix,PICORE': [1208], '(proximal': [1209], 'off': [1215, 1661, 2082], 'resonance': [1216, 2857], 'effects)': [1217], '(1)': [1219], 'thickness': [1223], 'gap': [1229], '2': [1231, 1447, 1900, 2814], 'slice.': [1240, 1347, 2195, 2320], 'each': [1242, 2129, 2444], 'shown,': [1245], '100': [1246, 1479], 'were': [1248, 2050], 'collected': [1249], '(50': [1250], 'tag/control': [1251], 'pairs),': [1252], 'average': [1255, 1596, 1627, 1688, 1742, 2608], 'control-tag': [1258], 'displayed.': [1259], 'evaluate': [1263, 1364], 'maximum': [1265, 2457], '(TI-TR)': [1268], 'fastest': [1271, 2538], 'flowing': [1272, 2180, 2539], 'arrives': [1275], 'plane': [1279], 'contaminates': [1281], 'signal,': [1284, 1829], 'varied': [1287], '1100–1400': [1289], 'fixed': [1293, 1384, 1435, 1586, 1678], '1000': [1295, 1438, 1589, 1666], 'ms.': [1296, 1387, 1590, 1667, 1682], 'bipolar': [1300], 'gradient': [1301], 'added': [1303], 'some': [1309], 'scans': [1310, 1373], 'dephase': [1314, 2536], 'spins': [1319, 1324, 1353], 'large': [1321, 1487, 1541, 1554, 1987], 'arteries.': [1322], 'earliest': [1327], 'most': [1336, 2206, 2567], 'likely': [1337], 'passing': [1340], 'through,': [1341], 'rather': [1342], 'perfusing,': [1344], 'Destroying': [1348], 'can': [1354, 1528, 2032, 2554, 2583, 2741], 'extend': [1355], 'usable': [1357], '(TR-TI).': [1360], 'lower': [1366, 1798], 'limit': [1367], 'series': [1371], 'acquired': [1375, 2051, 2058, 2569, 2586], 'ranging': [1378], '600–2000': [1380], '1100': [1386, 1621, 1681, 2055], 'experiment': [1390], 'normal': [1396], 'subject': [1397], '20-sec': [1399], 'periods': [1400, 1408], 'bilateral': [1402], 'finger': [1403], 'tapping': [1404], 'followed': [1405], '40-sec': [1407], 'rest,': [1410], 'repeated': [1411, 1417], 'six': [1412], 'times.': [1413], 'paradigm': [1415, 1764], 'PICORE': [1420, 1427, 1767, 1801, 1840, 1880, 1884, 1903, 2401], '(TR': [1421, 1428], '2000,': [1422], '1100)': [1424], '1000,': [1429], '1100).': [1431], 'RESULTS': [1432], 'values.': [1453], 'Average': [1454], 'whole-brain': [1462], 'gray': [1463], 'matter': [1464], 'interest': [1467], '(ROI)': [1468], 'plotted': [1471], 'figure.': [1474], 'weighting,': [1483], 'arteries': [1488], 'enters': [1489, 2173], 'artifactual': [1498, 1550], 'negative': [1499, 1533, 1551], 'With': [1503, 1543], 'weighting': [1505, 1584, 2533], 'VENC': [1509, 1545], '(velocity': [1510], 'π': [1513], 'phase': [1514], 'rotation)': [1515], '18': [1517, 1754], 'cm/sec,': [1518, 1548], 'up': [1524, 1561], '200': [1526], 'vessels.': [1542], '5': [1547, 2900], 'signals': [1552], 'vessels': [1555], 'nearly': [1557, 1813, 1859, 1932, 2615, 2762], 'eliminated': [1558], '400': [1563], 'but': [1565, 2019, 2332, 2387, 2644], 'itself': [1569], 'significantly': [1571], 'attenuated.': [1572], '2Open': [1574], 'vs.': [1580, 1675], '=': [1588, 1680], 'Top:': [1591, 1683], 'averaged': [1592, 1684], 'images.': [1594, 1615, 1686, 1737, 2240], 'Bottom:': [1595, 1687], 'arbitrary': [1600, 1692, 1893], 'units': [1601, 1693], 'whole': [1604, 1695], 'ROI.': [1606, 1697], 'axis': [1609, 1731], 'graph': [1613, 1735], 'constant': [1618], 'function': [1634], '3.': [1639], 'demonstrate': [1641], 'absolute': [1644, 1747, 1807, 1887], 'relatively': [1648], 'independent': [1649, 1781], 'wide': [1654], 'values,': [1658, 1707], 'falls': [1660, 2081], 'rapidly': [1662], '<': [1665, 2074], '3Open': [1669], 'continuous': [1702, 2108], 'spectrum': [1703], 'point': [1709, 1720, 1996], 'marked': [1710, 1721], 'PICORE,': [1717, 1918], 'B': [1722], 'PICORE.': [1728, 1770, 1909], 'shows': [1740], 'courses': [1744], 'ROI': [1752, 1772], 'activated': [1755, 2959], 'pixels': [1756], 'motor': [1759], 'cortex': [1760], 'during': [1761, 2339, 2443, 2887, 2926, 3034], 'correlation': [1776], 'analysis': [1777, 2411], 'FAIR': [1782, 2620], '(flow': [1783], 'alternated': [1784], 'recovery)': [1786], '(12)': [1787], 'experiment.': [1790], 'overall': [1793, 1912], '(as': [1802], '3),': [1805], 'change': [1809, 1921], 'activation': [1811, 1930], 'identical.': [1814, 1933], 'variance': [1816], 'course,': [1822], 'dominated': [1825, 2674], '3%': [1834], 'course.': [1842], 'indicates': [1844], 'changes': [1855, 2886, 3033], '4Open': [1870], '(triangles)': [1881], '(boxes).': [1885], 'scale': [1888], '(in': [1892], 'units),': [1894], '1': [1905, 2788], 'decreased': [1915], 'due': [1922], 'activation,': [1924], 'DISCUSSION': [1934], 'takes': [1944], 'increase': [1959, 1978, 2013, 2921], 'scan': [1961, 2755], 'An': [1969], 'unusual': [1970], 'feature': [1971, 2251], 'accompanied': [1984], 'CNR': [1991, 2737, 2760], 'main': [1995], 'work': [1999], 'specifically': [2002], 'simply': [2020], 'much': [2026, 2344], 'those': [2029], 'employed': [2031], 'little': [2036], 'reduction': [2037, 2735], '3,': [2044], 'example,': [2046], 'data': [2048, 2071, 2422], 'way': [2062, 2259], 'transition': [2068], 'smooth,': 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[2414], 'multiple': [2415, 2440], 'points': [2417], 'collected,': [2419], 'fit': [2423], 'model.': [2426, 2892, 2999], 'implementation': [2429], 'straightforward,': [2434], 'involves': [2436], 'rapid': [2437], 'locations': [2442], 'period.': [2447], 'efficiency,': [2459], 'ensure': [2463], 'slices': [2467], 'does': [2471], 'preceding': [2480], 'sequential': [2488], 'distal,': [2492], 'such': [2494, 2576], 'propagation': [2497], 'acquisitions': [2500], 'stays': [2501], 'ahead': [2502], 'leading': [2505], 'edge': [2506], 'wave': [2509], 'indicated': [2514], '2,': [2517], 'widened': [2526], 'small': [2531], 'gradients': [2534], 'spins.': [2541], 'issues': [2543], 'currently': [2545], 'under': [2546], 'experimental': [2547], 'investigation': [2548], 'laboratory.': [2551], 'combined': [2559], 'CBF/BOLD': [2560], 'studies.': [2561], 'efficiently': [2568, 2585], 'TE': [2573], 'spiral,': [2579], 'second': [2589], 'dual': [2593], 'positively': [2602], 'negatively': [2604], 'flow-weighted': 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