Pegylated interferon plus ribavirin versus non-pegylated interferon plus ribavirin for chronic hepatitis C

Name: Work Video:
Duration: 3 min 30 s
Description: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate the beneficial and harmful effects of pegylated interferon plus ribavirin versus non‐pegylated interferon plus ribavirin for chronic hepatitis C.
Marija Šimin; Jesper Brok; Davor Štimac; Christian Gluud; Lise Lotte Gluud
{'id': 'https://openalex.org/W4229934245', 'doi': 'https://doi.org/10.1002/14651858.cd005441', 'title': 'Pegylated interferon plus ribavirin versus non-pegylated interferon plus ribavirin for chronic hepatitis C', 'display_name': 'Pegylated interferon plus ribavirin versus non-pegylated interferon plus ribavirin for chronic hepatitis C', 'publication_year': 2005, 'publication_date': '2005-07-04', 'ids': {'openalex': 'https://openalex.org/W4229934245', 'doi': 'https://doi.org/10.1002/14651858.cd005441'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/14651858.cd005441', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S71429176', 'display_name': 'Cochrane database of systematic reviews', 'issn_l': '1361-6137', 'issn': ['1361-6137', '1469-493X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319727', 'host_organization_name': 'Cochrane', 'host_organization_lineage': ['https://openalex.org/P4310319727'], 'host_organization_lineage_names': ['Cochrane'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'reference-entry', 'type_crossref': 'reference-entry', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5005513338', 'display_name': 'Marija Šimin', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Marija Simin', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045906857', 'display_name': 'Jesper Brok', 'orcid': 'https://orcid.org/0000-0003-2576-0228'}, 'institutions': [{'id': 'https://openalex.org/I2802567020', 'display_name': 'Copenhagen University Hospital', 'ror': 'https://ror.org/05bpbnx46', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802567020']}, {'id': 'https://openalex.org/I2802709434', 'display_name': 'Rigshospitalet', 'ror': 'https://ror.org/03mchdq19', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802567020', 'https://openalex.org/I2802709434', 'https://openalex.org/I4210145385']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Jesper Brok', 'raw_affiliation_strings': ['Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital'], 'affiliations': [{'raw_affiliation_string': 'Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital', 'institution_ids': ['https://openalex.org/I2802567020', 'https://openalex.org/I2802709434']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065520120', 'display_name': 'Davor Štimac', 'orcid': 'https://orcid.org/0000-0001-8243-2453'}, 'institutions': [{'id': 'https://openalex.org/I138937732', 'display_name': 'University Hospital Centre Zagreb', 'ror': 'https://ror.org/00r9vb833', 'country_code': 'HR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I138937732']}], 'countries': ['HR'], 'is_corresponding': False, 'raw_author_name': 'Davor Stimac', 'raw_affiliation_strings': ['Clinical Hospital Centre of Rijeka'], 'affiliations': [{'raw_affiliation_string': 'Clinical Hospital Centre of Rijeka', 'institution_ids': ['https://openalex.org/I138937732']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019275846', 'display_name': 'Christian Gluud', 'orcid': 'https://orcid.org/0000-0002-8861-0799'}, 'institutions': [{'id': 'https://openalex.org/I2802567020', 'display_name': 'Copenhagen University Hospital', 'ror': 'https://ror.org/05bpbnx46', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802567020']}, {'id': 'https://openalex.org/I2802709434', 'display_name': 'Rigshospitalet', 'ror': 'https://ror.org/03mchdq19', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802567020', 'https://openalex.org/I2802709434', 'https://openalex.org/I4210145385']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Christian Gluud', 'raw_affiliation_strings': ['Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital'], 'affiliations': [{'raw_affiliation_string': 'Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital', 'institution_ids': ['https://openalex.org/I2802567020', 'https://openalex.org/I2802709434']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5114375523', 'display_name': 'Lise Lotte Gluud', 'orcid': 'https://orcid.org/0000-0002-9462-4468'}, 'institutions': [{'id': 'https://openalex.org/I2802567020', 'display_name': 'Copenhagen University Hospital', 'ror': 'https://ror.org/05bpbnx46', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802567020']}, {'id': 'https://openalex.org/I2802709434', 'display_name': 'Rigshospitalet', 'ror': 'https://ror.org/03mchdq19', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802567020', 'https://openalex.org/I2802709434', 'https://openalex.org/I4210145385']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Lise Lotte Gluud', 'raw_affiliation_strings': ['Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital'], 'affiliations': [{'raw_affiliation_string': 'Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital', 'institution_ids': ['https://openalex.org/I2802567020', 'https://openalex.org/I2802709434']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.25, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 76, 'max': 77}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10151', 'display_name': 'Hepatitis C virus research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10151', 'display_name': 'Hepatitis C virus research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10351', 'display_name': 'Liver Disease Diagnosis and Treatment', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10340', 'display_name': 'Hepatitis B Virus Studies', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pegylated-interferon', 'display_name': 'Pegylated interferon', 'score': 0.9076922}, {'id': 'https://openalex.org/keywords/hepatitis-c', 'display_name': 'Hepatitis C', 'score': 0.49968863}], 'concepts': [{'id': 'https://openalex.org/C2780040827', 'wikidata': 'https://www.wikidata.org/wiki/Q421862', 'display_name': 'Ribavirin', 'level': 4, 'score': 0.99083763}, {'id': 'https://openalex.org/C2776461080', 'wikidata': 'https://www.wikidata.org/wiki/Q7160835', 'display_name': 'Pegylated interferon', 'level': 5, 'score': 0.9076922}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.73753494}, {'id': 'https://openalex.org/C3020491458', 'wikidata': 'https://www.wikidata.org/wiki/Q131742', 'display_name': 'Chronic hepatitis', 'level': 3, 'score': 0.65485245}, {'id': 'https://openalex.org/C2776178377', 'wikidata': 'https://www.wikidata.org/wiki/Q188269', 'display_name': 'Interferon', 'level': 2, 'score': 0.613025}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.50190973}, {'id': 'https://openalex.org/C2776455275', 'wikidata': 'https://www.wikidata.org/wiki/Q154869', 'display_name': 'Hepatitis C', 'level': 2, 'score': 0.49968863}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.36511552}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.33772618}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.32139117}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.21743974}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/14651858.cd005441', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S71429176', 'display_name': 'Cochrane database of systematic reviews', 'issn_l': '1361-6137', 'issn': ['1361-6137', '1469-493X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319727', 'host_organization_name': 'Cochrane', 'host_organization_lineage': ['https://openalex.org/P4310319727'], 'host_organization_lineage_names': ['Cochrane'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.76, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1498961528', 'https://openalex.org/W150094635', 'https://openalex.org/W1598602811', 'https://openalex.org/W1964489041', 'https://openalex.org/W1973050866', 'https://openalex.org/W1974865799', 'https://openalex.org/W1975775441', 'https://openalex.org/W1984052453', 'https://openalex.org/W1987450796', 'https://openalex.org/W2000104469', 'https://openalex.org/W2005937502', 'https://openalex.org/W2015533723', 'https://openalex.org/W2027789718', 'https://openalex.org/W203587163', 'https://openalex.org/W2047208492', 'https://openalex.org/W2047766116', 'https://openalex.org/W2061108146', 'https://openalex.org/W2065986600', 'https://openalex.org/W2071873660', 'https://openalex.org/W2073566049', 'https://openalex.org/W2079462324', 'https://openalex.org/W2079634214', 'https://openalex.org/W2084417858', 'https://openalex.org/W2100227035', 'https://openalex.org/W2109048688', 'https://openalex.org/W2117294447', 'https://openalex.org/W2122905415', 'https://openalex.org/W2124352443', 'https://openalex.org/W2126930838', 'https://openalex.org/W2132290252', 'https://openalex.org/W2134338262', 'https://openalex.org/W2142337801', 'https://openalex.org/W2156574153', 'https://openalex.org/W2157823046', 'https://openalex.org/W2160795579', 'https://openalex.org/W2402582295', 'https://openalex.org/W4214559180', 'https://openalex.org/W4229970923', 'https://openalex.org/W4254857357'], 'related_works': ['https://openalex.org/W4229934245', 'https://openalex.org/W3149066399', 'https://openalex.org/W2605514927', 'https://openalex.org/W2321188506', 'https://openalex.org/W2318824964', 'https://openalex.org/W2108648362', 'https://openalex.org/W2078888723', 'https://openalex.org/W2067034737', 'https://openalex.org/W2055190024', 'https://openalex.org/W2009634266'], 'abstract_inverted_index': {'This': [0], 'is': [1], 'a': [2, 5], 'protocol': [3], 'for': [4, 31], 'Cochrane': [6], 'Review': [7], '(Intervention).': [8], 'The': [9], 'objectives': [10], 'are': [11], 'as': [12], 'follows:': [13], 'To': [14], 'evaluate': [15], 'the': [16], 'beneficial': [17], 'and': [18], 'harmful': [19], 'effects': [20], 'of': [21], 'pegylated': [22], 'interferon': [23, 28], 'plus': [24, 29], 'ribavirin': [25, 30], 'versus': [26], 'non‐pegylated': [27], 'chronic': [32], 'hepatitis': [33], 'C.': [34]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4229934245', 'counts_by_year': [], 'updated_date': '2024-12-15T10:18:00.744038', 'created_date': '2022-05-11'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
