Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4225324026', 'doi': 'https://doi.org/10.1080/14737140.2022.2069564', 'title': 'A review of the current status of lenalidomide maintenance therapy in multiple myeloma in 2022', 'display_name': 'A review of the current status of lenalidomide maintenance therapy in multiple myeloma in 2022', 'publication_year': 2022, 'publication_date': '2022-05-03', 'ids': {'openalex': 'https://openalex.org/W4225324026', 'doi': 'https://doi.org/10.1080/14737140.2022.2069564', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/35503516'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/14737140.2022.2069564', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S93370067', 'display_name': 'Expert Review of Anticancer Therapy', 'issn_l': '1473-7140', 'issn': ['1473-7140', '1744-8328'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103488314', 'display_name': 'Ravi Kumar Gupta', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802655110', 'display_name': 'Larkin Community Hospital', 'ror': 'https://ror.org/02wcweb64', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802655110']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Ravi Kumar Gupta', 'raw_affiliation_strings': ['Department of Internal Medicine, Larkin Community Hospital, South Miami, Florida, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Larkin Community Hospital, South Miami, Florida, USA', 'institution_ids': ['https://openalex.org/I2802655110']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042518019', 'display_name': 'Ashish Gupta', 'orcid': 'https://orcid.org/0000-0002-3038-9067'}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ashish Gupta', 'raw_affiliation_strings': ['Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA', 'institution_ids': ['https://openalex.org/I1292894508']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068472643', 'display_name': 'Jens Hillengaß', 'orcid': 'https://orcid.org/0000-0002-1778-0010'}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jens Hillengass', 'raw_affiliation_strings': ['Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA', 'institution_ids': ['https://openalex.org/I1292894508']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005732386', 'display_name': 'Sarah A. Holstein', 'orcid': 'https://orcid.org/0000-0002-9342-5635'}, 'institutions': [{'id': 'https://openalex.org/I59130452', 'display_name': 'University of Nebraska Medical Center', 'ror': 'https://ror.org/00thqtb16', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I59130452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sarah A. Holstein', 'raw_affiliation_strings': ['Department of Internal Medicine, Division of Oncology and Hematology, University of Nebraska Medical Center, Omaha, NE, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Division of Oncology and Hematology, University of Nebraska Medical Center, Omaha, NE, USA', 'institution_ids': ['https://openalex.org/I59130452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082661564', 'display_name': 'Vera J. Suman', 'orcid': 'https://orcid.org/0000-0002-9640-5189'}, 'institutions': [{'id': 'https://openalex.org/I1330342723', 'display_name': 'Mayo Clinic', 'ror': 'https://ror.org/02qp3tb03', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1330342723']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Vera J. Suman', 'raw_affiliation_strings': ['Department of Health Sciences, Division of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Sciences, Division of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA', 'institution_ids': ['https://openalex.org/I1330342723']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038321186', 'display_name': 'Alankrita Taneja', 'orcid': 'https://orcid.org/0000-0002-7231-2623'}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alankrita Taneja', 'raw_affiliation_strings': ['Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA', 'institution_ids': ['https://openalex.org/I1292894508']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063351800', 'display_name': 'Philip L. McCarthy', 'orcid': 'https://orcid.org/0000-0002-9577-3879'}, 'institutions': [{'id': 'https://openalex.org/I1292894508', 'display_name': 'Roswell Park Comprehensive Cancer Center', 'ror': 'https://ror.org/0499dwk57', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1292894508']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Philip L. McCarthy', 'raw_affiliation_strings': ['Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA', 'institution_ids': ['https://openalex.org/I1292894508']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5103488314'], 'corresponding_institution_ids': ['https://openalex.org/I2802655110'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.324, 'has_fulltext': False, 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.998413, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 80, 'max': 83}, 'biblio': {'volume': '22', 'issue': '5', 'first_page': '457', 'last_page': '469'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10649', 'display_name': 'Multiple Myeloma Research and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10649', 'display_name': 'Multiple Myeloma Research and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12534', 'display_name': 'Protein Degradation and Inhibitors', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin and proteasome pathways', 'score': 0.9938, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/maintenance-therapy', 'display_name': 'Maintenance therapy', 'score': 0.8159833}, {'id': 'https://openalex.org/keywords/tolerability', 'display_name': 'Tolerability', 'score': 0.73395365}, {'id': 'https://openalex.org/keywords/autologous-stem-cell-transplantation', 'display_name': 'Autologous stem-cell transplantation', 'score': 0.4648565}, {'id': 'https://openalex.org/keywords/combination-therapy', 'display_name': 'Combination therapy', 'score': 0.43858162}, {'id': 'https://openalex.org/keywords/salvage-therapy', 'display_name': 'Salvage therapy', 'score': 0.41707903}], 'concepts': [{'id': 'https://openalex.org/C2776063141', 'wikidata': 'https://www.wikidata.org/wiki/Q425681', 'display_name': 'Lenalidomide', 'level': 3, 'score': 0.9657239}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8612033}, {'id': 'https://openalex.org/C2778283404', 'wikidata': 'https://www.wikidata.org/wiki/Q6736822', 'display_name': 'Maintenance therapy', 'level': 3, 'score': 0.8159833}, {'id': 'https://openalex.org/C2778375690', 'wikidata': 'https://www.wikidata.org/wiki/Q7814214', 'display_name': 'Tolerability', 'level': 3, 'score': 0.73395365}, {'id': 'https://openalex.org/C2776364478', 'wikidata': 'https://www.wikidata.org/wiki/Q467635', 'display_name': 'Multiple myeloma', 'level': 2, 'score': 0.6603876}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.5339061}, {'id': 'https://openalex.org/C2779050716', 'wikidata': 'https://www.wikidata.org/wiki/Q4826373', 'display_name': 'Autologous stem-cell transplantation', 'level': 3, 'score': 0.4648565}, {'id': 'https://openalex.org/C2776999253', 'wikidata': 'https://www.wikidata.org/wiki/Q1304270', 'display_name': 'Combination therapy', 'level': 2, 'score': 0.43858162}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4287813}, {'id': 'https://openalex.org/C2780775027', 'wikidata': 'https://www.wikidata.org/wiki/Q17141389', 'display_name': 'Salvage therapy', 'level': 3, 'score': 0.41707903}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.33570486}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.20834717}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.12958062}], 'mesh': [{'descriptor_ui': 'D018380', 'descriptor_name': 'Hematopoietic Stem Cell Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009101', 'descriptor_name': 'Multiple Myeloma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000971', 'descriptor_name': 'Antineoplastic Combined Chemotherapy Protocols', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000971', 'descriptor_name': 'Antineoplastic Combined Chemotherapy Protocols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077269', 'descriptor_name': 'Lenalidomide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060046', 'descriptor_name': 'Maintenance Chemotherapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009101', 'descriptor_name': 'Multiple Myeloma', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D014182', 'descriptor_name': 'Transplantation, Autologous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/14737140.2022.2069564', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S93370067', 'display_name': 'Expert Review of Anticancer Therapy', 'issn_l': '1473-7140', 'issn': ['1473-7140', '1744-8328'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/35503516', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.7, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 75, 'referenced_works': ['https://openalex.org/W1527383154', 'https://openalex.org/W1594485137', 'https://openalex.org/W1986297232', 'https://openalex.org/W1990362490', 'https://openalex.org/W1996965637', 'https://openalex.org/W2004136640', 'https://openalex.org/W2004903490', 'https://openalex.org/W2014207161', 'https://openalex.org/W2015345028', 'https://openalex.org/W2018729528', 'https://openalex.org/W2026448323', 'https://openalex.org/W2043759160', 'https://openalex.org/W2068412287', 'https://openalex.org/W2100545964', 'https://openalex.org/W2107384529', 'https://openalex.org/W2108601475', 'https://openalex.org/W2109013784', 'https://openalex.org/W2114217833', 'https://openalex.org/W2122728054', 'https://openalex.org/W2123826310', 'https://openalex.org/W2125721471', 'https://openalex.org/W2125965467', 'https://openalex.org/W2128084036', 'https://openalex.org/W2135915916', 'https://openalex.org/W2142368474', 'https://openalex.org/W2143425592', 'https://openalex.org/W2164130043', 'https://openalex.org/W2164667231', 'https://openalex.org/W2167310611', 'https://openalex.org/W2168980644', 'https://openalex.org/W2169210165', 'https://openalex.org/W2212499331', 'https://openalex.org/W2308917761', 'https://openalex.org/W2462945035', 'https://openalex.org/W2512106959', 'https://openalex.org/W2518827451', 'https://openalex.org/W2528329272', 'https://openalex.org/W2588162473', 'https://openalex.org/W2592857667', 'https://openalex.org/W2593617117', 'https://openalex.org/W2703436965', 'https://openalex.org/W2737964630', 'https://openalex.org/W2746456353', 'https://openalex.org/W2784400197', 'https://openalex.org/W2786804053', 'https://openalex.org/W2802804971', 'https://openalex.org/W2883225871', 'https://openalex.org/W2890152252', 'https://openalex.org/W2904294860', 'https://openalex.org/W2904778784', 'https://openalex.org/W2906522930', 'https://openalex.org/W2909552152', 'https://openalex.org/W2910689817', 'https://openalex.org/W2913321588', 'https://openalex.org/W3004783871', 'https://openalex.org/W3006419152', 'https://openalex.org/W3013063217', 'https://openalex.org/W3019889711', 'https://openalex.org/W3021098306', 'https://openalex.org/W3092622634', 'https://openalex.org/W3097797153', 'https://openalex.org/W3113412439', 'https://openalex.org/W3114333169', 'https://openalex.org/W3119005666', 'https://openalex.org/W3136388199', 'https://openalex.org/W3136849454', 'https://openalex.org/W3153907740', 'https://openalex.org/W3176465782', 'https://openalex.org/W3200717490', 'https://openalex.org/W3206192616', 'https://openalex.org/W3212279449', 'https://openalex.org/W3212617436', 'https://openalex.org/W4200135655', 'https://openalex.org/W4200312283', 'https://openalex.org/W4235854784'], 'related_works': ['https://openalex.org/W87448443', 'https://openalex.org/W4225324026', 'https://openalex.org/W4207044329', 'https://openalex.org/W2982687159', 'https://openalex.org/W2757904155', 'https://openalex.org/W2547590150', 'https://openalex.org/W2437623268', 'https://openalex.org/W2313428075', 'https://openalex.org/W2197780007', 'https://openalex.org/W2130647755'], 'abstract_inverted_index': {'Introduction': [0], 'Recent': [1], 'advances': [2], 'in': [3, 18, 25, 89, 94, 157, 175], 'the': [4, 76, 121, 141, 170, 176], 'diagnosis': [5], 'and': [6, 42, 62, 96, 115, 127, 129, 143], 'management': [7], 'of': [8, 21, 47, 132, 172], 'multiple': [9], 'myeloma': [10], '(MM)': [11], 'have': [12, 66], 'improved': [13], 'patient': [14], 'outcomes.': [15], 'This': [16, 73, 136], 'progress': [17], 'our': [19], 'understanding': [20], 'MM': [22], 'has': [23, 50], 'resulted': [24], 'continuous': [26], 'suppressive': [27], 'therapy': [28, 49, 86, 156, 174], 'concepts,': [29], 'including': [30], 'induction,': [31], 'high': [32], 'dose': [33], 'chemotherapy': [34], 'with': [35, 52, 82, 91, 103, 112, 159], 'autologous': [36], 'stem': [37], 'cell': [38], 'transplantation': [39], '(ASCT),': [40], 'consolidation,': [41], 'maintenance': [43, 48, 85, 134, 155, 177], 'therapy.': [44, 135], 'The': [45], 'foundation': [46], 'been': [51], 'lenalidomide.': [53], 'Other': [54], 'novel': [55], 'immunomodulatory': [56], 'drugs': [57], '(IMiDs),': [58], 'proteasome': [59], 'inhibitors': [60], '(PIs),': [61], 'targeted': [63], 'monoclonal': [64], 'antibodies': [65], 'also': [67, 119], 'contributed': [68], 'to': [69, 139, 166], 'this': [70], 'evolution.Areas': [71], 'covered': [72], 'review': [74, 106, 120, 137], 'summarizes': [75], 'outcomes': [77], 'from': [78], 'phase': [79], 'II/III': [80], 'trials': [81], 'long-term': [83], 'lenalidomide': [84, 133, 150, 168], 'alone': [87], 'or': [88], 'combination': [90, 111, 173], 'other': [92], 'agents': [93], 'post-ASCT': [95], 'non-transplant': [97], 'settings': [98], 'for': [99, 154], 'newly': [100], 'diagnosed': [101], 'patients': [102, 158], 'MM.': [104], 'We': [105, 118], 'recent': [107], 'data': [108], 'considering': [109], 'a': [110, 152], 'newer': [113], 'medications': [114], 'ongoing': [116], 'trials.': [117], 'optimal': [122], 'duration,': [123], 'MRD': [124], 'negativity': [125], 'rate,': [126], 'safety': [128], 'tolerability': [130], 'aspects': [131], 'aims': [138], 'present': [140], 'current': [142], 'emerging': [144], 'clinical': [145], 'evidence': [146, 165], 'that': [147], 'supports': [148], 'using': [149], 'as': [151, 169], 'backbone': [153, 171], 'MM.Expert': [160], 'opinion': [161], 'There': [162], 'is': [163], 'increasing': [164], 'support': [167], 'setting.': [178]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4225324026', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}], 'updated_date': '2025-01-08T07:08:02.309389', 'created_date': '2022-05-05'}