Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4224101605', 'doi': 'https://doi.org/10.1186/s43043-022-00100-y', 'title': 'The need to identify novel biomarkers for prediction of premature ovarian insufficiency (POI)', 'display_name': 'The need to identify novel biomarkers for prediction of premature ovarian insufficiency (POI)', 'publication_year': 2022, 'publication_date': '2022-04-18', 'ids': {'openalex': 'https://openalex.org/W4224101605', 'doi': 'https://doi.org/10.1186/s43043-022-00100-y'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s43043-022-00100-y', 'pdf_url': 'https://mefj.springeropen.com/track/pdf/10.1186/s43043-022-00100-y', 'source': {'id': 'https://openalex.org/S133968747', 'display_name': 'Middle East Fertility Society Journal', 'issn_l': '1110-5690', 'issn': ['1110-5690', '2090-3251'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj'], 'open_access': {'is_oa': True, 'oa_status': 'diamond', 'oa_url': 'https://mefj.springeropen.com/track/pdf/10.1186/s43043-022-00100-y', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5009447477', 'display_name': 'Roya Kabodmehri', 'orcid': 'https://orcid.org/0000-0003-4162-6846'}, 'institutions': [{'id': 'https://openalex.org/I204331812', 'display_name': 'Guilan University of Medical Sciences', 'ror': 'https://ror.org/04ptbrd12', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I204331812', 'https://openalex.org/I4210110574']}], 'countries': ['IR'], 'is_corresponding': False, 'raw_author_name': 'Roya Kabodmehri', 'raw_affiliation_strings': ['Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran'], 'affiliations': [{'raw_affiliation_string': 'Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran', 'institution_ids': ['https://openalex.org/I204331812']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073540930', 'display_name': 'Seyedeh Hajar Sharami', 'orcid': 'https://orcid.org/0000-0001-7815-3769'}, 'institutions': [{'id': 'https://openalex.org/I204331812', 'display_name': 'Guilan University of Medical Sciences', 'ror': 'https://ror.org/04ptbrd12', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I204331812', 'https://openalex.org/I4210110574']}], 'countries': ['IR'], 'is_corresponding': False, 'raw_author_name': 'Seyedeh Hajar Sharami', 'raw_affiliation_strings': ['Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran'], 'affiliations': [{'raw_affiliation_string': 'Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran', 'institution_ids': ['https://openalex.org/I204331812']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079444812', 'display_name': 'Zahra Rafiei Sorouri', 'orcid': 'https://orcid.org/0000-0003-2286-6983'}, 'institutions': [{'id': 'https://openalex.org/I204331812', 'display_name': 'Guilan University of Medical Sciences', 'ror': 'https://ror.org/04ptbrd12', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I204331812', 'https://openalex.org/I4210110574']}], 'countries': ['IR'], 'is_corresponding': False, 'raw_author_name': 'Zahra Rafiei Sorouri', 'raw_affiliation_strings': ['Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran'], 'affiliations': [{'raw_affiliation_string': 'Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran', 'institution_ids': ['https://openalex.org/I204331812']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5031865746', 'display_name': 'Nasrin Ghanami Gashti', 'orcid': 'https://orcid.org/0000-0003-0060-3955'}, 'institutions': [{'id': 'https://openalex.org/I204331812', 'display_name': 'Guilan University of Medical Sciences', 'ror': 'https://ror.org/04ptbrd12', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I204331812', 'https://openalex.org/I4210110574']}], 'countries': ['IR'], 'is_corresponding': False, 'raw_author_name': 'Nasrin Ghanami Gashti', 'raw_affiliation_strings': ['Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran'], 'affiliations': [{'raw_affiliation_string': 'Reproductive Health Research Center, Department of Obstetrics & Gynecology, Al-Zahra Hospital, School of Medicine, Guilan University of Medical Sciences, P.O. Box 4144654839, Rasht, Iran', 'institution_ids': ['https://openalex.org/I204331812']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 0, 'currency': 'USD', 'value_usd': 0, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.913, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.744802, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 76, 'max': 80}, 'biblio': {'volume': '27', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10390', 'display_name': 'Ovarian function and disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10390', 'display_name': 'Ovarian function and disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10364', 'display_name': 'Reproductive Biology and Fertility', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10550', 'display_name': 'Ovarian cancer diagnosis and treatment', 'score': 0.9844, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/premature-ovarian-failure', 'display_name': 'Premature ovarian failure', 'score': 0.9589823}, {'id': 'https://openalex.org/keywords/premature-ovarian-insufficiency', 'display_name': 'Premature ovarian insufficiency', 'score': 0.9446329}, {'id': 'https://openalex.org/keywords/female-infertility', 'display_name': 'Female infertility', 'score': 0.4470246}, {'id': 'https://openalex.org/keywords/ovarian-reserve', 'display_name': 'Ovarian Reserve', 'score': 0.429739}, {'id': 'https://openalex.org/keywords/unexplained-infertility', 'display_name': 'Unexplained infertility', 'score': 0.42709637}], 'concepts': [{'id': 'https://openalex.org/C2777395788', 'wikidata': 'https://www.wikidata.org/wiki/Q647630', 'display_name': 'Premature ovarian failure', 'level': 2, 'score': 0.9589823}, {'id': 'https://openalex.org/C2911206770', 'wikidata': 'https://www.wikidata.org/wiki/Q647630', 'display_name': 'Premature ovarian insufficiency', 'level': 2, 'score': 0.9446329}, {'id': 'https://openalex.org/C2777688143', 'wikidata': 'https://www.wikidata.org/wiki/Q179399', 'display_name': 'Infertility', 'level': 3, 'score': 0.794417}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5997127}, {'id': 'https://openalex.org/C2781197716', 'wikidata': 'https://www.wikidata.org/wiki/Q864574', 'display_name': 'Biomarker', 'level': 2, 'score': 0.5831088}, {'id': 'https://openalex.org/C2779647306', 'wikidata': 'https://www.wikidata.org/wiki/Q648065', 'display_name': 'Female infertility', 'level': 4, 'score': 0.4470246}, {'id': 'https://openalex.org/C2776600139', 'wikidata': 'https://www.wikidata.org/wiki/Q7113253', 'display_name': 'Ovarian reserve', 'level': 4, 'score': 0.429739}, {'id': 'https://openalex.org/C2778580812', 'wikidata': 'https://www.wikidata.org/wiki/Q686627', 'display_name': 'Unexplained infertility', 'level': 4, 'score': 0.42709637}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.3971737}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.35570037}, {'id': 'https://openalex.org/C29456083', 'wikidata': 'https://www.wikidata.org/wiki/Q1221899', 'display_name': 'Gynecology', 'level': 1, 'score': 0.3159812}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.28682154}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.119831234}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s43043-022-00100-y', 'pdf_url': 'https://mefj.springeropen.com/track/pdf/10.1186/s43043-022-00100-y', 'source': {'id': 'https://openalex.org/S133968747', 'display_name': 'Middle East Fertility Society Journal', 'issn_l': '1110-5690', 'issn': ['1110-5690', '2090-3251'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/3863d001345944db8284a4eb37a12fea', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s43043-022-00100-y', 'pdf_url': 'https://mefj.springeropen.com/track/pdf/10.1186/s43043-022-00100-y', 'source': {'id': 'https://openalex.org/S133968747', 'display_name': 'Middle East Fertility Society Journal', 'issn_l': '1110-5690', 'issn': ['1110-5690', '2090-3251'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.81, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1913232349', 'https://openalex.org/W1969710082', 'https://openalex.org/W1990911325', 'https://openalex.org/W2023055629', 'https://openalex.org/W2025613570', 'https://openalex.org/W2027676461', 'https://openalex.org/W2028988822', 'https://openalex.org/W2034168643', 'https://openalex.org/W2038121812', 'https://openalex.org/W2046347487', 'https://openalex.org/W2058186210', 'https://openalex.org/W2065000675', 'https://openalex.org/W2083537238', 'https://openalex.org/W2091959120', 'https://openalex.org/W2101249317', 'https://openalex.org/W2106449365', 'https://openalex.org/W2106610310', 'https://openalex.org/W2127964403', 'https://openalex.org/W2131499333', 'https://openalex.org/W2132445852', 'https://openalex.org/W2134198398', 'https://openalex.org/W2139921809', 'https://openalex.org/W2167142860', 'https://openalex.org/W2171251470', 'https://openalex.org/W2178374371', 'https://openalex.org/W2205768504', 'https://openalex.org/W2309700868', 'https://openalex.org/W2322135964', 'https://openalex.org/W2376777244', 'https://openalex.org/W2396888170', 'https://openalex.org/W2400433712', 'https://openalex.org/W2467084345', 'https://openalex.org/W2507722016', 'https://openalex.org/W2532658875', 'https://openalex.org/W2561623215', 'https://openalex.org/W2603584561', 'https://openalex.org/W2604669862', 'https://openalex.org/W2732516376', 'https://openalex.org/W2769122638', 'https://openalex.org/W2774310489', 'https://openalex.org/W2781979705', 'https://openalex.org/W2811059483', 'https://openalex.org/W2814647648', 'https://openalex.org/W2836578072', 'https://openalex.org/W2890610003', 'https://openalex.org/W2891822000', 'https://openalex.org/W2904144016', 'https://openalex.org/W2907324822', 'https://openalex.org/W2907630226', 'https://openalex.org/W2911464522', 'https://openalex.org/W2912444667', 'https://openalex.org/W2920390696', 'https://openalex.org/W2945517418', 'https://openalex.org/W2947538449', 'https://openalex.org/W2958279967', 'https://openalex.org/W2979777167', 'https://openalex.org/W2980609320', 'https://openalex.org/W2992397131', 'https://openalex.org/W3010058524', 'https://openalex.org/W3097683220', 'https://openalex.org/W3119817948'], 'related_works': ['https://openalex.org/W4312920393', 'https://openalex.org/W4224101605', 'https://openalex.org/W4212805473', 'https://openalex.org/W3009704512', 'https://openalex.org/W2977457118', 'https://openalex.org/W2941059461', 'https://openalex.org/W2793258156', 'https://openalex.org/W2412519933', 'https://openalex.org/W2332525088', 'https://openalex.org/W1781570'], 'abstract_inverted_index': {'Abstract': [0], 'Background': [1], 'Premature': [2], 'ovarian': [3, 6, 13, 100, 103, 211], 'failure': [4], '(POF)/premature': [5], 'insufficiency': [7], '(POI)': [8], 'is': [9, 26, 155, 185], 'characterized': [10], 'by': [11, 92], 'disrupting': [12], 'function': [14], 'under': [15], '40': [16], 'years': [17], 'old.': [18], 'A': [19, 80], 'major': [20], 'health': [21], 'problem': [22], 'of': [23, 38, 63, 69, 74, 126, 167, 169, 204, 209], 'this': [24, 77], 'disorder': [25], 'female': [27], 'infertility.': [28], 'There': [29], 'are': [30], 'no': [31], 'proven': [32], 'treatments': [33, 57], 'to': [34, 49, 59, 143, 159, 162], 'increase': [35], 'the': [36, 61, 67, 115, 118, 121, 127, 165, 207], 'rate': [37], 'pregnancy': [39], 'with': [40, 76, 196], 'autologous': [41], 'oocytes': [42], 'in': [43, 66, 114, 194, 202], 'these': [44], 'patients.': [45], 'This': [46], 'review': [47, 82], 'aims': [48], 'summarize': [50], 'our': [51], 'present': [52], 'knowledge': [53], 'about': [54, 187], 'POI-induced': [55], 'infertility': [56, 182], 'and': [58, 72, 88, 105, 124, 181], 'highlight': [60], 'importance': [62], 'future': [64], 'researches': [65], 'discovery': [68], 'diagnostic': [70, 149, 198], 'biomarkers': [71], 'treatment': [73, 183], 'patients': [75], 'disorder.': [78], 'Methods': [79], 'literature': [81], 'was': [83], 'carried': [84], 'out': [85], 'using': [86], 'PubMed': [87], 'Google': [89], 'Scholar': [90], 'databases': [91], 'relevant': [93, 134], 'keywords,': [94], 'such': [95], 'as': [96, 147], 'POI,': [97, 152], 'POF,': [98], 'premature': [99, 102], 'failure,': [101], 'insufficiency,': [104], 'biomarkers.': [106], 'Results': [107], 'Two': [108], 'hundred': [109], 'three': [110], 'studies': [111], 'were': [112, 130], 'included': [113], 'study': [116], 'following': [117], 'search': [119], 'for': [120, 132, 151], 'keywords.': [122], 'Titles': [123], 'abstracts': [125], 'identified': [128], 'articles': [129], 'evaluated': [131], 'detecting': [133], 'full-length': [135], 'articles.': [136], 'Conclusion': [137], 'Anti-Mullerian': [138], 'hormone': [139], '(AMH)': [140], 'level': [141], 'appears': [142], 'have': [144], 'considerable': [145], 'value': [146], 'a': [148], 'test': [150], 'but': [153], 'it': [154], 'not': [156], 'reliable': [157], 'enough': [158], 'be': [160, 178, 189], 'able': [161], 'predict': [163], 'accurately': [164], 'timing': [166], 'onset': [168], 'impending': [170], 'POI.': [171], 'Using': [172], 'an': [173], 'accurate': [174], 'biomarker,': [175], 'POI': [176, 205], 'can': [177, 188], 'diagnosed': [179], 'early': [180], 'that': [184], 'concerned': [186], 'done': [190], 'on': [191], 'time.': [192], 'Biomarkers': [193], 'combination': [195], 'other': [197], 'tests': [199], 'could': [200], 'result': [201], 'prediction': [203], 'before': [206], 'development': [208], 'complete': [210], 'failure.': [212]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4224101605', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-12-12T22:36:12.066144', 'created_date': '2022-04-19'}