Abstract: This report contains the description of more than a hundred publications in which pharmacophore mapping, usually with 3D searching, has identified experimentally verified biologically active compounds. For some of the recent examples pharmacophores were developed from the 3D structure of a protein-ligand complex; in other cases the pharmacophore description was augmented with a criterion based on the observed shape of the binding site.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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Cited By Count: 1
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