Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4220996396', 'doi': 'https://doi.org/10.1146/annurev-biochem-072321-110228', 'title': 'The Initiation of Eukaryotic DNA Replication', 'display_name': 'The Initiation of Eukaryotic DNA Replication', 'publication_year': 2022, 'publication_date': '2022-03-23', 'ids': {'openalex': 'https://openalex.org/W4220996396', 'doi': 'https://doi.org/10.1146/annurev-biochem-072321-110228', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/35320688'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1146/annurev-biochem-072321-110228', 'pdf_url': 'https://www.annualreviews.org/doi/pdf/10.1146/annurev-biochem-072321-110228', 'source': {'id': 'https://openalex.org/S53860259', 'display_name': 'Annual Review of Biochemistry', 'issn_l': '0066-4154', 'issn': ['0066-4154', '1545-4509'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320373', 'host_organization_name': 'Annual Reviews', 'host_organization_lineage': ['https://openalex.org/P4310320373'], 'host_organization_lineage_names': ['Annual Reviews'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.annualreviews.org/doi/pdf/10.1146/annurev-biochem-072321-110228', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5082896494', 'display_name': 'Alessandro Costa', 'orcid': 'https://orcid.org/0000-0003-1126-2498'}, 'institutions': [{'id': 'https://openalex.org/I2801081054', 'display_name': 'The Francis Crick Institute', 'ror': 'https://ror.org/04tnbqb63', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I2801081054']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Alessandro Costa', 'raw_affiliation_strings': ['Macromolecular Machines Laboratory, The Francis Crick Institute, London, UK;'], 'affiliations': [{'raw_affiliation_string': 'Macromolecular Machines Laboratory, The Francis Crick Institute, London, UK;', 'institution_ids': ['https://openalex.org/I2801081054']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5029333589', 'display_name': 'John F.X. Diffley', 'orcid': 'https://orcid.org/0000-0001-5184-7680'}, 'institutions': [{'id': 'https://openalex.org/I2801081054', 'display_name': 'The Francis Crick Institute', 'ror': 'https://ror.org/04tnbqb63', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I2801081054']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'John F.X. Diffley', 'raw_affiliation_strings': ['Chromosome Replication Laboratory, The Francis Crick Institute, London, UK;'], 'affiliations': [{'raw_affiliation_string': 'Chromosome Replication Laboratory, The Francis Crick Institute, London, UK;', 'institution_ids': ['https://openalex.org/I2801081054']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 7.16, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 156, 'citation_normalized_percentile': {'value': 0.999875, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '91', 'issue': '1', 'first_page': '107', 'last_page': '131'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/origin-recognition-complex', 'display_name': 'Origin recognition complex', 'score': 0.8054372}, {'id': 'https://openalex.org/keywords/pre-replication-complex', 'display_name': 'Pre-replication complex', 'score': 0.7572003}, {'id': 'https://openalex.org/keywords/licensing-factor', 'display_name': 'Licensing factor', 'score': 0.6618992}, {'id': 'https://openalex.org/keywords/minichromosome-maintenance', 'display_name': 'Minichromosome maintenance', 'score': 0.6265558}, {'id': 'https://openalex.org/keywords/dna-re-replication', 'display_name': 'DNA re-replication', 'score': 0.5503464}, {'id': 'https://openalex.org/keywords/replication-factor-c', 'display_name': 'Replication factor C', 'score': 0.5137897}, {'id': 'https://openalex.org/keywords/semiconservative-replication', 'display_name': 'Semiconservative replication', 'score': 0.48708037}], 'concepts': [{'id': 'https://openalex.org/C151158763', 'wikidata': 'https://www.wikidata.org/wiki/Q1626856', 'display_name': 'Origin recognition complex', 'level': 5, 'score': 0.8054372}, {'id': 'https://openalex.org/C104690221', 'wikidata': 'https://www.wikidata.org/wiki/Q5165872', 'display_name': 'Control of chromosome duplication', 'level': 4, 'score': 0.79911274}, {'id': 'https://openalex.org/C41141232', 'wikidata': 'https://www.wikidata.org/wiki/Q3685229', 'display_name': 'Pre-replication complex', 'level': 5, 'score': 0.7572003}, {'id': 'https://openalex.org/C98086919', 'wikidata': 'https://www.wikidata.org/wiki/Q118019', 'display_name': 'Eukaryotic DNA replication', 'level': 4, 'score': 0.72751516}, {'id': 'https://openalex.org/C54266558', 'wikidata': 'https://www.wikidata.org/wiki/Q6543075', 'display_name': 'Licensing factor', 'level': 5, 'score': 0.6618992}, {'id': 'https://openalex.org/C73573662', 'wikidata': 'https://www.wikidata.org/wiki/Q130996', 'display_name': 'DNA replication', 'level': 3, 'score': 0.62772214}, {'id': 'https://openalex.org/C175248279', 'wikidata': 'https://www.wikidata.org/wiki/Q3858415', 'display_name': 'Minichromosome maintenance', 'level': 5, 'score': 0.6265558}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.55261135}, {'id': 'https://openalex.org/C67419583', 'wikidata': 'https://www.wikidata.org/wiki/Q5205768', 'display_name': 'DNA re-replication', 'level': 5, 'score': 0.5503464}, {'id': 'https://openalex.org/C58337764', 'wikidata': 'https://www.wikidata.org/wiki/Q976651', 'display_name': 'Origin of replication', 'level': 4, 'score': 0.5225853}, {'id': 'https://openalex.org/C188036394', 'wikidata': 'https://www.wikidata.org/wiki/Q14902224', 'display_name': 'Replication factor C', 'level': 5, 'score': 0.5137897}, {'id': 'https://openalex.org/C13052165', 'wikidata': 'https://www.wikidata.org/wiki/Q1208348', 'display_name': 'Semiconservative replication', 'level': 5, 'score': 0.48708037}, {'id': 'https://openalex.org/C175193931', 'wikidata': 'https://www.wikidata.org/wiki/Q18047065', 'display_name': 'DNA replication factor CDT1', 'level': 5, 'score': 0.4737678}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.46866927}, {'id': 'https://openalex.org/C161223559', 'wikidata': 'https://www.wikidata.org/wiki/Q138864', 'display_name': 'Helicase', 'level': 4, 'score': 0.4605519}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.45581904}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.37910742}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.14679879}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.07652944}], 'mesh': [{'descriptor_ui': 'D056890', 'descriptor_name': 'Eukaryota', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005057', 'descriptor_name': 'Eukaryotic Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004261', 'descriptor_name': 'DNA Replication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056890', 'descriptor_name': 'Eukaryota', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005057', 'descriptor_name': 'Eukaryotic Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018741', 'descriptor_name': 'Replication Origin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1146/annurev-biochem-072321-110228', 'pdf_url': 'https://www.annualreviews.org/doi/pdf/10.1146/annurev-biochem-072321-110228', 'source': {'id': 'https://openalex.org/S53860259', 'display_name': 'Annual Review of Biochemistry', 'issn_l': '0066-4154', 'issn': ['0066-4154', '1545-4509'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320373', 'host_organization_name': 'Annual Reviews', 'host_organization_lineage': ['https://openalex.org/P4310320373'], 'host_organization_lineage_names': ['Annual Reviews'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/35320688', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1146/annurev-biochem-072321-110228', 'pdf_url': 'https://www.annualreviews.org/doi/pdf/10.1146/annurev-biochem-072321-110228', 'source': {'id': 'https://openalex.org/S53860259', 'display_name': 'Annual Review of Biochemistry', 'issn_l': '0066-4154', 'issn': ['0066-4154', '1545-4509'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320373', 'host_organization_name': 'Annual Reviews', 'host_organization_lineage': ['https://openalex.org/P4310320373'], 'host_organization_lineage_names': ['Annual Reviews'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.44, 'id': 'https://metadata.un.org/sdg/15', 'display_name': 'Life on land'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 193, 'referenced_works': ['https://openalex.org/W1136494239', 'https://openalex.org/W1506793089', 'https://openalex.org/W1566625041', 'https://openalex.org/W1597133026', 'https://openalex.org/W1936654228', 'https://openalex.org/W1964317450', 'https://openalex.org/W1964429281', 'https://openalex.org/W1967579846', 'https://openalex.org/W1968074226', 'https://openalex.org/W1969518299', 'https://openalex.org/W1970471893', 'https://openalex.org/W1970732313', 'https://openalex.org/W1971017541', 'https://openalex.org/W1972424135', 'https://openalex.org/W1972654719', 'https://openalex.org/W1974306997', 'https://openalex.org/W1975001355', 'https://openalex.org/W1975939844', 'https://openalex.org/W1978617734', 'https://openalex.org/W1980042463', 'https://openalex.org/W1983485056', 'https://openalex.org/W1985481802', 'https://openalex.org/W1985491895', 'https://openalex.org/W1987861824', 'https://openalex.org/W1992334813', 'https://openalex.org/W1992675473', 'https://openalex.org/W1993464551', 'https://openalex.org/W1994051286', 'https://openalex.org/W1994605002', 'https://openalex.org/W1995594264', 'https://openalex.org/W1995958788', 'https://openalex.org/W1997378173', 'https://openalex.org/W2002326161', 'https://openalex.org/W2002907731', 'https://openalex.org/W2003279154', 'https://openalex.org/W2005498658', 'https://openalex.org/W2005962907', 'https://openalex.org/W2006706909', 'https://openalex.org/W2007214324', 'https://openalex.org/W2010885478', 'https://openalex.org/W2011396983', 'https://openalex.org/W2012931476', 'https://openalex.org/W2013815592', 'https://openalex.org/W2014463884', 'https://openalex.org/W2014717496', 'https://openalex.org/W2016628718', 'https://openalex.org/W2016864528', 'https://openalex.org/W2018782003', 'https://openalex.org/W2019808923', 'https://openalex.org/W2020058603', 'https://openalex.org/W2021803200', 'https://openalex.org/W2022562381', 'https://openalex.org/W2026160273', 'https://openalex.org/W2026642300', 'https://openalex.org/W2027594270', 'https://openalex.org/W2030333676', 'https://openalex.org/W2035982764', 'https://openalex.org/W2036285677', 'https://openalex.org/W2038174431', 'https://openalex.org/W2039307706', 'https://openalex.org/W2040778486', 'https://openalex.org/W2041837518', 'https://openalex.org/W2044279758', 'https://openalex.org/W2044440192', 'https://openalex.org/W2045178475', 'https://openalex.org/W2046707499', 'https://openalex.org/W2049171516', 'https://openalex.org/W2056590571', 'https://openalex.org/W2057587708', 'https://openalex.org/W2057594508', 'https://openalex.org/W2058104615', 'https://openalex.org/W2059531322', 'https://openalex.org/W2059594509', 'https://openalex.org/W2060636149', 'https://openalex.org/W2061449183', 'https://openalex.org/W2064154094', 'https://openalex.org/W2065971145', 'https://openalex.org/W2071019833', 'https://openalex.org/W2072472133', 'https://openalex.org/W2072897152', 'https://openalex.org/W2074317111', 'https://openalex.org/W2075450948', 'https://openalex.org/W2080835326', 'https://openalex.org/W2082128798', 'https://openalex.org/W2083389050', 'https://openalex.org/W2084518357', 'https://openalex.org/W2085365618', 'https://openalex.org/W2085898164', 'https://openalex.org/W2086693806', 'https://openalex.org/W2087412911', 'https://openalex.org/W2089983883', 'https://openalex.org/W2090081894', 'https://openalex.org/W2091038230', 'https://openalex.org/W2093703127', 'https://openalex.org/W2094429878', 'https://openalex.org/W2095146606', 'https://openalex.org/W2097164868', 'https://openalex.org/W2099117602', 'https://openalex.org/W2099487576', 'https://openalex.org/W2104190830', 'https://openalex.org/W2105413529', 'https://openalex.org/W2105439835', 'https://openalex.org/W2108084815', 'https://openalex.org/W2108654668', 'https://openalex.org/W2112302692', 'https://openalex.org/W2112429774', 'https://openalex.org/W2113126534', 'https://openalex.org/W2113305379', 'https://openalex.org/W2113991648', 'https://openalex.org/W2116004354', 'https://openalex.org/W2117757271', 'https://openalex.org/W2120137820', 'https://openalex.org/W2120628590', 'https://openalex.org/W2124694478', 'https://openalex.org/W2125717020', 'https://openalex.org/W2127043939', 'https://openalex.org/W2130483978', 'https://openalex.org/W2134870735', 'https://openalex.org/W2138734522', 'https://openalex.org/W2140230014', 'https://openalex.org/W2140380500', 'https://openalex.org/W2141149624', 'https://openalex.org/W2142260588', 'https://openalex.org/W2143028761', 'https://openalex.org/W2143955948', 'https://openalex.org/W2144892831', 'https://openalex.org/W2151527633', 'https://openalex.org/W2152115601', 'https://openalex.org/W2152731657', 'https://openalex.org/W2154662820', 'https://openalex.org/W2161533283', 'https://openalex.org/W2161921221', 'https://openalex.org/W2165735315', 'https://openalex.org/W2170326957', 'https://openalex.org/W2170955251', 'https://openalex.org/W2194086801', 'https://openalex.org/W2256007651', 'https://openalex.org/W2264582589', 'https://openalex.org/W2279836301', 'https://openalex.org/W2289012084', 'https://openalex.org/W2462761630', 'https://openalex.org/W2472184758', 'https://openalex.org/W2517008357', 'https://openalex.org/W2558144350', 'https://openalex.org/W2562393208', 'https://openalex.org/W2566002255', 'https://openalex.org/W2578571972', 'https://openalex.org/W2588219103', 'https://openalex.org/W2588444668', 'https://openalex.org/W2588958371', 'https://openalex.org/W2594597600', 'https://openalex.org/W2604825272', 'https://openalex.org/W2625839772', 'https://openalex.org/W2737463560', 'https://openalex.org/W2750812953', 'https://openalex.org/W2754218973', 'https://openalex.org/W2771250096', 'https://openalex.org/W2787975097', 'https://openalex.org/W2810211328', 'https://openalex.org/W2889812869', 'https://openalex.org/W2912332641', 'https://openalex.org/W2916972625', 'https://openalex.org/W2954869700', 'https://openalex.org/W2959460977', 'https://openalex.org/W2964264171', 'https://openalex.org/W2966483144', 'https://openalex.org/W2971471877', 'https://openalex.org/W2975794575', 'https://openalex.org/W2979826783', 'https://openalex.org/W2989260338', 'https://openalex.org/W2989746390', 'https://openalex.org/W2991537080', 'https://openalex.org/W3003362033', 'https://openalex.org/W3004470337', 'https://openalex.org/W3009470867', 'https://openalex.org/W3021801309', 'https://openalex.org/W3033112179', 'https://openalex.org/W3035859142', 'https://openalex.org/W3042458246', 'https://openalex.org/W3044067169', 'https://openalex.org/W3065139950', 'https://openalex.org/W3081489159', 'https://openalex.org/W3093163345', 'https://openalex.org/W3124020797', 'https://openalex.org/W3126212514', 'https://openalex.org/W3128623005', 'https://openalex.org/W3131928754', 'https://openalex.org/W3137250368', 'https://openalex.org/W3148058208', 'https://openalex.org/W3152114558', 'https://openalex.org/W3174255068', 'https://openalex.org/W4248756242', 'https://openalex.org/W54002301'], 'related_works': ['https://openalex.org/W4387601259', 'https://openalex.org/W4386209166', 'https://openalex.org/W2434643092', 'https://openalex.org/W2098324291', 'https://openalex.org/W2090376445', 'https://openalex.org/W2087013595', 'https://openalex.org/W2086995149', 'https://openalex.org/W2057896961', 'https://openalex.org/W1979452570', 'https://openalex.org/W1547945395'], 'abstract_inverted_index': {'DNA': [0, 55], 'replication': [1, 12, 16], 'in': [2, 32, 47], 'eukaryotic': [3], 'cells': [4], 'initiates': [5], 'from': [6, 17, 72, 85], 'large': [7], 'numbers': [8], 'of': [9, 15, 42, 52, 68], 'sites': [10], 'called': [11], 'origins.': [13], 'Initiation': [14], 'these': [18, 69], 'origins': [19], 'must': [20], 'be': [21], 'tightly': [22], 'controlled': [23], 'to': [24], 'ensure': [25], 'the': [26, 40, 43, 53, 64], 'entire': [27], 'genome': [28], 'is': [29, 37, 61], 'precisely': [30], 'duplicated': [31], 'each': [33], 'cell': [34], 'cycle.': [35], 'This': [36], 'accomplished': [38], 'through': [39], 'regulation': [41, 67], 'first': [44], 'two': [45, 70], 'steps': [46], 'replication:': [48], 'loading': [49], 'and': [50, 66, 76], 'activation': [51], 'replicative': [54], 'helicase.': [56], 'Here': [57], 'we': [58], 'describe': [59], 'what': [60], 'known': [62], 'about': [63], 'mechanism': [65], 'reactions': [71], 'a': [73], 'genetic,': [74], 'biochemical,': [75], 'structural': [77], 'perspective,': [78], 'focusing': [79], 'on': [80], 'recent': [81], 'progress': [82], 'using': [83], 'proteins': [84], 'budding': [86], 'yeast.': [87]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4220996396', 'counts_by_year': [{'year': 2024, 'cited_by_count': 87}, {'year': 2023, 'cited_by_count': 54}, {'year': 2022, 'cited_by_count': 10}], 'updated_date': '2025-01-15T19:55:25.561775', 'created_date': '2022-04-03'}