Publication Information

{'id': 'https://openalex.org/W4220729690', 'doi': 'https://doi.org/10.1158/1538-7445.sabcs21-p5-13-18', 'title': 'Abstract P5-13-18: Upregulation of immune response biomarkers by ribociclib plus endocrine therapy (ET) in paired tumor samples from phase I studies', 'display_name': 'Abstract P5-13-18: Upregulation of immune response biomarkers by ribociclib plus endocrine therapy (ET) in paired tumor samples from phase I studies', 'publication_year': 2022, 'publication_date': '2022-02-15', 'ids': {'openalex': 'https://openalex.org/W4220729690', 'doi': 'https://doi.org/10.1158/1538-7445.sabcs21-p5-13-18'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.sabcs21-p5-13-18', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087308492', 'display_name': 'Dejan Juric', 'orcid': 'https://orcid.org/0000-0003-2983-7704'}, 'institutions': [{'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dejan Juric', 'raw_affiliation_strings': ['Massachusetts General Hospital Cancer Center, Boston, MA'], 'affiliations': [{'raw_affiliation_string': 'Massachusetts General Hospital Cancer Center, Boston, MA', 'institution_ids': ['https://openalex.org/I4210087915']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051301947', 'display_name': 'Chong Ma', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210117619', 'display_name': 'Novartis (United States)', 'ror': 'https://ror.org/028fhxy95', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1283582996', 'https://openalex.org/I4210117619']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chong Ma', 'raw_affiliation_strings': ['Novartis Pharmaceuticals Corporation, Cambridge, MA'], 'affiliations': [{'raw_affiliation_string': 'Novartis Pharmaceuticals Corporation, Cambridge, MA', 'institution_ids': ['https://openalex.org/I4210117619']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089355202', 'display_name': 'Ralph Tiedt', 'orcid': 'https://orcid.org/0000-0002-9825-859X'}, 'institutions': [{'id': 'https://openalex.org/I4400600974', 'display_name': 'Novartis Institutes for BioMedical Research', 'ror': 'https://ror.org/053gv2m95', 'country_code': None, 'type': None, 'lineage': ['https://openalex.org/I1283582996', 'https://openalex.org/I4400600974']}, {'id': 'https://openalex.org/I1283582996', 'display_name': 'Novartis (Switzerland)', 'ror': 'https://ror.org/02f9zrr09', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I1283582996']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Ralph Tiedt', 'raw_affiliation_strings': ['Novartis Institutes for BioMedical Research, Oncology Translational Research, Basel, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Novartis Institutes for BioMedical Research, Oncology Translational Research, Basel, Switzerland', 'institution_ids': ['https://openalex.org/I4400600974', 'https://openalex.org/I1283582996']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052352446', 'display_name': 'Yoon Sim Yap', 'orcid': 'https://orcid.org/0000-0002-0347-5066'}, 'institutions': [{'id': 'https://openalex.org/I4210137145', 'display_name': 'National Cancer Centre Singapore', 'ror': 'https://ror.org/03bqk3e80', 'country_code': 'SG', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137145']}], 'countries': ['SG'], 'is_corresponding': False, 'raw_author_name': 'Yoon-Sim Yap', 'raw_affiliation_strings': ['National Cancer Center Singapore, Singapore City, Singapore'], 'affiliations': [{'raw_affiliation_string': 'National Cancer Center Singapore, Singapore City, Singapore', 'institution_ids': ['https://openalex.org/I4210137145']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015909215', 'display_name': 'Joanne Chiu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800810863', 'display_name': 'Queen Mary Hospital', 'ror': 'https://ror.org/02xkx3e48', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1294586568', 'https://openalex.org/I2800810863']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Joanne Chiu', 'raw_affiliation_strings': ['Queen Mary Hospital, Hong Kong, China'], 'affiliations': [{'raw_affiliation_string': 'Queen Mary Hospital, Hong Kong, China', 'institution_ids': ['https://openalex.org/I2800810863']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083373965', 'display_name': 'Pamela N. Münster', 'orcid': 'https://orcid.org/0000-0002-2074-0984'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Pamela Munster', 'raw_affiliation_strings': ['University of California San Francisco, San Francisco, CA'], 'affiliations': [{'raw_affiliation_string': 'University of California San Francisco, San Francisco, CA', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015970851', 'display_name': 'Roohi Ismail‐Khan', 'orcid': 'https://orcid.org/0000-0002-1301-6736'}, 'institutions': [{'id': 'https://openalex.org/I3019308854', 'display_name': 'Moffitt Cancer Center', 'ror': 'https://ror.org/01xf75524', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019308854']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Roohi Ismail-Khan', 'raw_affiliation_strings': ['H. Lee Moffitt Cancer Center, Tampa, FL'], 'affiliations': [{'raw_affiliation_string': 'H. Lee Moffitt Cancer Center, Tampa, FL', 'institution_ids': ['https://openalex.org/I3019308854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062581318', 'display_name': 'Laura García‐Estévez', 'orcid': 'https://orcid.org/0000-0002-1709-8097'}, 'institutions': [{'id': 'https://openalex.org/I4210137474', 'display_name': 'Hospital Universitario HM Sanchinarro', 'ror': 'https://ror.org/04jep6391', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210122338', 'https://openalex.org/I4210137474']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Laura Garcia-Estevez', 'raw_affiliation_strings': ['Hospital de San Chinarro, Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Hospital de San Chinarro, Madrid, Spain', 'institution_ids': ['https://openalex.org/I4210137474']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069182089', 'display_name': 'Ingrid A. Mayer', 'orcid': 'https://orcid.org/0000-0001-8147-335X'}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}, {'id': 'https://openalex.org/I4390039299', 'display_name': 'Vanderbilt-Ingram Cancer Center', 'ror': 'https://ror.org/02rjj2m04', 'country_code': None, 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210162197', 'https://openalex.org/I4390039299', 'https://openalex.org/I901861585']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ingrid A. Mayer', 'raw_affiliation_strings': ['Vanderbilt-Ingram Cancer Center, Nashville, TN'], 'affiliations': [{'raw_affiliation_string': 'Vanderbilt-Ingram Cancer Center, Nashville, TN', 'institution_ids': ['https://openalex.org/I200719446', 'https://openalex.org/I4390039299']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110145965', 'display_name': 'Carlos Becerra', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800124591', 'display_name': 'Texas Oncology', 'ror': 'https://ror.org/02ketev28', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I2800124591']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Carlos Becerra', 'raw_affiliation_strings': ['Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, TX', 'institution_ids': ['https://openalex.org/I2800124591']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041227452', 'display_name': 'Nadia Solovieff', 'orcid': 'https://orcid.org/0000-0001-6140-7304'}, 'institutions': [{'id': 'https://openalex.org/I4210117619', 'display_name': 'Novartis (United States)', 'ror': 'https://ror.org/028fhxy95', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1283582996', 'https://openalex.org/I4210117619']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nadia Solovieff', 'raw_affiliation_strings': ['Novartis Institutes for Biomedical Research, Cambridge, MA'], 'affiliations': [{'raw_affiliation_string': 'Novartis Institutes for Biomedical Research, Cambridge, MA', 'institution_ids': ['https://openalex.org/I4210117619']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067617700', 'display_name': 'Agnes Lteif', 'orcid': 'https://orcid.org/0009-0000-2065-7091'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Agnes Lteif', 'raw_affiliation_strings': ['Novartis Pharmaceuticals Corporation, East Hanover, NJ'], 'affiliations': [{'raw_affiliation_string': 'Novartis Pharmaceuticals Corporation, East Hanover, NJ', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005415248', 'display_name': 'Faye Su', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Faye Su', 'raw_affiliation_strings': ['Novartis Pharmaceuticals Corporation, East Hanover, NJ'], 'affiliations': [{'raw_affiliation_string': 'Novartis Pharmaceuticals Corporation, East Hanover, NJ', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009846821', 'display_name': 'Yen‐Shen Lu', 'orcid': 'https://orcid.org/0000-0001-7461-1291'}, 'institutions': [{'id': 'https://openalex.org/I4210131804', 'display_name': 'National Taiwan University Hospital', 'ror': 'https://ror.org/03nteze27', 'country_code': 'TW', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210131804']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Yen-Shen Lu', 'raw_affiliation_strings': ['National Taiwan University Hospital, Taipei, Taiwan'], 'affiliations': [{'raw_affiliation_string': 'National Taiwan University Hospital, Taipei, Taiwan', 'institution_ids': ['https://openalex.org/I4210131804']}]}], 'institution_assertions': [], 'countries_distinct_count': 6, 'institutions_distinct_count': 13, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 60}, 'biblio': {'volume': '82', 'issue': '4_Supplement', 'first_page': 'P5', 'last_page': '18'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12829', 'display_name': 'Advanced Breast Cancer Therapies', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12829', 'display_name': 'Advanced Breast Cancer Therapies', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12334', 'display_name': 'Lung Cancer Research Studies', 'score': 0.9834, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.9766, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.6572409}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5477275}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.53567016}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.5021262}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.4838187}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.43119586}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.40638614}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.38690078}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.sabcs21-p5-13-18', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.86, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4313472242', 'https://openalex.org/W4211132779', 'https://openalex.org/W2989121736', 'https://openalex.org/W2892677547', 'https://openalex.org/W2375584271', 'https://openalex.org/W2357948923', 'https://openalex.org/W2332159055', 'https://openalex.org/W2030500189', 'https://openalex.org/W1997105855', 'https://openalex.org/W1972945471'], 'abstract_inverted_index': {'Abstract': [0], 'Background:': [1], 'In': [2], 'addition': [3], 'to': [4, 14, 62, 140, 227, 280, 395], 'inhibiting': [5], 'cell': [6, 236], 'cycle': [7, 154, 371], 'progression,': [8], 'CDK4/6': [9, 41, 430], 'inhibitors': [10], 'have': [11, 65], 'been': [12, 68], 'found': [13], 'modulate': [15], 'anti-cancer': [16, 45], 'immune': [17, 38, 247, 314, 426, 467], 'response': [18, 54, 248, 320, 468], '(Goel': [19], 'S,': [20, 79, 87], 'et': [21, 80, 88, 202, 269], 'al.': [22, 81, 89, 203, 270], 'Nature.': [23], '2017;548:471-475).': [24], 'Data': [25], 'from': [26, 73, 108, 158, 169, 173, 296, 480], 'preclinical': [27, 63], 'studies': [28, 483], 'suggested': [29], 'multiple': [30], 'mechanisms—involving': [31], 'changes': [32, 309, 408], 'in': [33, 119, 123, 146, 163, 246, 285, 321, 348, 388, 398, 432, 476], 'both': [34], 'cancer': [35, 76, 127, 322, 349], 'cells': [36, 315], 'and': [37, 56, 105, 110, 171, 181, 192, 223, 231, 345, 361, 372], 'cells—by': [39], 'which': [40, 335], 'inhibition': [42, 431], 'can': [43], 'enhance': [44], 'immunity.': [46], 'These': [47, 251], 'mechanisms': [48], 'include': [49], 'increased': [50, 311], 'antigen': [51, 343], 'presentation,': [52], 'interferon': [53, 319], 'triggering,': [55], 'regulatory': [57], 'T-cell': [58], 'suppression.': [59], 'Clinical': [60], 'correlates': [61], 'observations': [64], 'so': [66], 'far': [67], 'obtained': [69], 'using': [70], 'paired': [71, 103, 477], 'biopsies': [72, 107, 298], 'neoadjuvant': [74], 'breast': [75, 126], 'trials': [77, 116, 162], '(Johnston': [78], 'J': [82, 271], 'Clin': [83, 90, 272], 'Oncol.': [84, 206], '2019;37:178-189;': [85], 'Hurvitz': [86], 'Cancer': [91, 493, 504], 'Res.': [92], '2020;': [93], ';26:566-80).': [94], 'Here,': [95], 'we': [96, 301], 'describe': [97], 'a': [98, 257, 262, 290, 357, 385], 'gene': [99, 186, 196, 258], 'expression': [100, 142, 187, 241, 308], 'analysis': [101, 188, 353], 'of': [102, 143, 149, 189, 234, 242, 261, 425, 466, 487], 'pre-': [104], 'on-treatment': [106], 'CLEE011A2115C': [109, 170], 'CLEE011X2107,': [111], 'two': [112, 159], 'phase': [113, 160, 481], 'I': [114, 161, 482], 'clinical': [115, 291, 405, 422], 'evaluating': [117], 'ribociclib': [118, 180, 471], 'combination': [120], 'with': [121, 179, 215, 283, 356], 'ET': [122], 'the': [124, 164, 235, 306, 420, 488], 'metastatic': [125], '(MBC)': [128], 'setting.': [129], 'Methods:': [130], 'The': [131, 324], 'nCounter': [132], 'PanCancer': [133], 'IO': [134], '360': [135], 'Panel': [136], '(NanoString)': [137], 'was': [138, 198, 249, 275, 299, 354, 391], 'used': [139], 'quantify': [141], '770': [144], 'genes': [145, 191, 210, 244, 278, 390], '7': [147], 'pairs': [148], 'tumor': [150, 265, 297, 478], 'samples': [151, 479], '(baseline': [152], 'vs.': [153], '1': [155, 412], 'day': [156, 413], '15)': [157], 'MBC': [165], 'setting': [166], '(5': [167], 'patients': [168, 176, 286, 399], '2': [172], 'CLEE011X2107).': [174], 'All': [175], 'were': [177, 212, 225, 252], 'treated': [178], 'an': [182, 317], 'ET.': [183], 'Pairwise': [184], 'differential': [185], 'individual': [190], 'previously': [193, 333], 'published': [194], 'immune-related': [195, 389], 'signatures': [197], 'conducted': [199, 355], '(Bedognetti': [200], 'D,': [201], 'Curr': [204], 'Opin': [205], '2015;27:433-444).': [207], 'Results:': [208], 'Many': [209], 'that': [211, 393], 'markedly': [213], 'suppressed': [214], 'treatment': [216, 284, 380], '(eg,': [217], 'MKI67,': [218], 'MYC,': [219], 'CDK2,': [220], 'CCNB1,': [221], 'TYMS,': [222], 'DNMT1)': [224], 'related': [226], 'proliferation,': [228], 'DNA': [229], 'replication,': [230], 'G1/S': [232], 'transition': [233], 'cycle,': [237], 'as': [238, 382], 'expected.': [239, 383], 'Interestingly,': [240], 'numerous': [243], 'involved': [245], 'increased.': [250], 'mostly': [253], 'interferon-regulated': [254], 'genes;': [255], 'particularly,': [256], 'signature': [259], 'indicative': [260], 'T': [263, 338], 'cell-inflamed': [264], 'microenvironment': [266], '(Ayers': [267], 'M,': [268], 'Invest.': [273], '2017;127:2930-2940)': [274], 'upregulated.': [276], 'Immune-related': [277], 'tended': [279, 394], 'preferentially': [281, 397], 'increase': [282, 387], 'who': [287, 400], 'later': [288, 401], 'experienced': [289, 402], 'response.': [292], 'Since': [293], 'bulk': [294], 'RNA': [295], 'analyzed,': [300], 'could': [302, 326], 'not': [303], 'distinguish': [304], 'whether': [305], 'observed': [307], 'reflected': [310], 'infiltration': [312], 'by': [313, 329, 341, 378, 429, 470], 'or': [316], 'endogenous': [318], 'cells.': [323, 350], 'latter': [325], 'be': [327], 'triggered': [328], 'DNMT1': [330], 'suppression': [331, 377], '(as': [332], 'described),': [334], 'then': [336], 'promotes': [337], 'cell-mediated': [339], 'immunity': [340], 'increasing': [342], 'presentation': [344], 'chemokine': [346], 'production': [347], 'Conclusions:': [351], 'This': [352], 'small': [358], 'sample': [359], 'size': [360], 'is': [362, 368, 419], 'considered': [363], 'hypothesis': [364], 'generating;': [365], 'further': [366], 'investigation': [367], 'needed.': [369], 'Cell': [370], 'proliferation': [373], 'markers': [374], 'showed': [375], 'robust': [376], 'ribociclib-based': [379], 'regimens,': [381], 'Conversely,': [384], 'notable': [386], 'detected': [392], 'occur': [396], 'more': [403], 'favorable': [404], 'outcomes.': [406], 'Both': [407], 'occurred': [409], 'early': [410], '(cycle': [411], '15).': [414], 'To': [415], 'our': [416], 'knowledge,': [417], 'this': [418], 'first': [421], 'biomarker': [423], 'report': [424], 'activation': [427], 'mediated': [428], 'MBC.': [433], 'Citation': [434], 'Format:': [435], 'Dejan': [436], 'Juric,': [437], 'Chong': [438], 'Ma,': [439], 'Ralph': [440], 'Tiedt,': [441], 'Yoon-Sim': [442], 'Yap,': [443], 'Joanne': [444], 'Chiu,': [445], 'Pamela': [446], 'Munster,': [447], 'Roohi': [448], 'Ismail-Khan,': [449], 'Laura': [450], 'Garcia-Estevez,': [451], 'Ingrid': [452], 'A.': [453], 'Mayer,': [454], 'Carlos': [455], 'Becerra,': [456], 'Nadia': [457], 'Solovieff,': [458], 'Agnes': [459], 'Lteif,': [460], 'Faye': [461], 'Su,': [462], 'Yen-Shen': [463], 'Lu.': [464], 'Upregulation': [465], 'biomarkers': [469], 'plus': [472], 'endocrine': [473], 'therapy': [474], '(ET)': [475], '[abstract].': [484], 'In:': [485], 'Proceedings': [486], '2021': [489, 495], 'San': [490, 498], 'Antonio': [491], 'Breast': [492], 'Symposium;': [494], 'Dec': [496], '7-10;': [497], 'Antonio,': [499], 'TX.': [500], 'Philadelphia': [501], '(PA):': [502], 'AACR;': [503], 'Res': [505], '2022;82(4': [506], 'Suppl):Abstract': [507], 'nr': [508], 'P5-13-18.': [509]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4220729690', 'counts_by_year': [], 'updated_date': '2024-12-15T10:18:33.918111', 'created_date': '2022-04-03'}