Title: Experimental investigations on effects of ZnO NPS and annona muricata extract for in vitro and in vivo antibacterial activity
Abstract: ZnO NPs and annona muricata extract was used as antibacterial against some pathogenic bacteria isolated from different sources of infections. Furthermore, this work demonstrated the effect of oral dosage of ZnO NPs and annona muricata extract on the infected experimental animals. Moreover, the results showed the sensitivity of studied bacteria is variance against ZnO NPs and annona muricata extract and this sensitivity increase with increasing the concentration of both ZnO NPs and annona muricata extract. The in vitro study included using five bacterial species (S.aureus, S.epidermidis, P.aeruginosa, Proteus sp. and E.coli) and two in vivo studies (S.aureus and E.coli) which were given orally to experimental animals to verify the antibacterial activity of ZnO NPs and annona muricata extract against infections resulting from these pathogenic bacteria. The results were showed the effectiveness of ZnO NPs and annona muricata extract and no negative effect to be used as antibacterial agents. Therefore, this study can be considered important in the field of medicine, because the results of healing are very effective for these two substances.
Publication Year: 2022
Publication Date: 2022-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 2
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