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1349], 'additive.': [342, 458, 575], 'Silver': [343, 1065, 1067, 1622, 1779, 1820, 2128, 2291, 2470, 2624, 2719, 3044, 3452], 'in': [344, 351, 434, 488, 551, 563, 602, 644, 745, 788, 937, 995, 1047, 1093, 1133, 1159, 1222, 1324, 1359, 1386, 1390, 1392, 1395, 1508, 1554, 1559, 1590, 1628, 1696, 1726, 1764, 1767, 1781, 1830, 1856, 1930, 2010, 2031, 2133, 2137, 2207, 2296, 2300, 2370, 2391, 2510, 2540, 2631, 2635, 2680, 2725, 2803, 2817, 2920, 2945, 2981, 3049, 3078, 3090, 3136, 3177, 3206, 3226, 3247, 3274, 3371, 3430, 3454, 3518, 3551, 3555, 3658, 3660, 3696, 3730, 3788, 3816, 3851], 'E': [347, 470, 515, 528, 3317], '174': [348, 471, 516, 529, 3318], 'is': [349, 432, 1865, 3363], 'its': [352, 1471, 1529, 3369], 'elemental': [353, 389, 415], 'form.': [354], 'noted': [357], 'there': [359], 'are': [360], 'gaps': [362, 2630], 'concerns': [364], 'be': [366, 419, 519, 615, 1348], 'addressed': [367], 'conduct': [369], 'risk': [371, 1284, 1315, 2598, 3561], 'assessment': [372, 1285, 1316, 1469, 2599], 'respect': [374], 'use': [377, 1132], '174):': [381], 'lack': [382], 'toxicity': [386, 491, 1689, 1826, 1855, 2174, 2656, 2832, 2977, 3027, 3048, 3512], 'studies': [387, 504], 'or': [391, 591, 872, 896], '174);': [396, 406], 'unknown': [397, 433], 'particle': [398, 534, 537, 1868, 3020], 'size': [399, 535, 538, 814, 1851, 3021], 'distribution': [400, 539], 'evidence': [407, 3367], 'release': [410, 427, 477, 2413, 3616], 'ions': [413, 431, 1649, 1929, 2006, 3362, 3517, 3657], 'from': [414, 1432, 1437, 2064, 2084, 2097, 2418, 2825, 3070, 3341, 3395, 3620], 'silver,': [416, 991], 'which': [417], 'may': [418], 'concern.': [421], 'However,': [422], 'extent': [424], 'case': [436], '174).': [440], 'concluded': [443, 496], 'information': [446, 483], 'available': [447, 490, 502], 'was': [448], 'insufficient': [449], 'assess': [451], 'major': [460], 'issues': [461], 'included': [462], 'chemical': [463], 'identification': [464], 'an': [465, 787, 2130, 2293, 2626, 3659], 'd': [466], 'characterisation': [467], '(e.g.': [472], 'quantity': [473], 'nanoparticles': [475, 643, 744, 779, 1467, 1623, 1646, 2177, 2509, 2539, 3135, 3182, 3619, 3654, 3780], 'ionic': [479, 1694, 1762], 'silver)': [480], 'similar': [482, 1756], 'material': [486], 'studies.': [492, 3680], 'Therefore,': [493], 'relevance': [499], 'toxicological': [503], 'evaluation': [508, 610, 706, 1115, 1822, 2653, 2833], 'could': [517], 'not': [518], 'established.': [520], 'recommended': [523, 598], 'specifications': [526], 'should': [530, 579], 'include': [531], 'mean': [533], '(±': [540], 'SD),': [541], 'well': [543], 'percentage': [546], '(in': [547], 'number)': [548], 'particles': [550], 'nanoscale': [553], '(with': [554], 'at': [555, 941, 2178], 'least': [556], 'one': [557], 'dimension': [558], '100': [560], 'nm),': [561], 'powder': [565], 'form': [566], 'methodology': [577], 'applied': [578, 1184], 'comply': [580], 'Guidance': [584, 607, 1249, 1312, 1342], 'document,': [585], 'e.g.': [586], 'scanning': [587, 3103], 'electron': [588, 593, 3106, 3466], 'microscopy': [589, 594, 3285], '(SEM)': [590], 'transmission': [592, 3105], '(TEM).': [595], 'additional': [600], 'line': [603], 'current': [606], 'document': [608], 'additives': [613, 1289], 'would': [614], 'required.': [616], 'References': [617], 'Ahamed': [618], 'M,': [619, 621, 623, 729, 912, 978, 1452, 1572, 1607, 1620, 1803, 2241, 2253, 2260, 2496, 2568, 2570, 3480, 3531, 3574, 3801, 3843], 'Karns': [620], 'Goodson': [622], 'Rowe': [624], 'J,': [625, 755, 1413, 1574, 1601, 1615, 1920, 2247, 2346, 2403, 2427, 2488, 2524, 2743, 2795, 2961, 2969, 3198, 3263, 3494, 3608, 3711, 3764], 'Hussain': [626], 'SM,': [627, 3414], 'Schlager': [628], 'JJ': [629, 3265], 'Hong': [631, 844], 'Y,': [632, 886, 2199, 2342, 2348, 2352, 2670, 2700, 2702, 2963, 3390], '2008.': [633, 859, 3751], 'DNA': [634, 1824, 2263], 'damage': [635, 2264], 'response': [636], 'different': [638, 942], 'surface': [639, 830], 'chemistry': [640], 'mammalian': [645], 'cells.': [646, 747, 1653, 1834, 2185, 2332, 2728], 'Toxicology': [647, 748, 899, 1630, 1700, 1735, 1835, 2160, 2218, 2277, 2760, 2989, 3080, 3294, 3436], 'Applied': [649, 1734, 3293], 'Pharmacology': [650], '233,': [651], '404–': [652], '410.': [653], 'ANSES': [654, 684, 691], '(French': [655, 692], 'Agency': [656, 693], 'Food,': [658, 695, 3335], 'Environmental': [659, 696, 2215, 2395, 2729, 2759, 2988, 3438], 'Occupational': [661, 698, 1074], 'Health': [662, 699, 1062, 1566, 2076, 2216, 2864, 3439, 3748], 'Safety),': [664, 701], '2011.': [665, 773, 1308, 1819, 2651, 3016, 3391], 'Second': [666], 'French': [667], 'Total': [668, 3192], 'Diet': [669], 'Study': [670, 1922, 2092, 2859], '(TDS': [671], '2),': [672], 'Report': [673, 2060, 3564], '1.': [674], 'Inorganic': [675, 915, 2480], 'contaminants,': [676], 'minerals,': [677], 'persistent': [678], 'organic': [679], 'pollutants,': [680], 'mycotoxins': [681], 'phytoestrogens.': [683], 'Opinion,': [685], 'Expert': [686, 2045], 'Report,': [687], '4.7,': [688], 'p': [689], '44.': [690], '2015.': [702, 810, 1209, 2147, 2590, 2880, 3043, 3609, 3773], 'Opinion': [703, 1085, 1111, 1310, 1492, 3307], 'health': [709], 'environmental': [711], 'risks': [712], 'linked': [713], 'exposure': [716, 869, 1095, 3777], 'AgNPs.': [718, 1594, 2214, 2276, 2659, 2987, 3031], 'Available': [719, 839, 974, 1495, 2063, 2083, 2788, 2824, 2881, 3320, 3568, 3758], 'https://www.anses.fr/en/system/files/AP2011sa0224Ra.pdf': [721], 'Asare': [722], 'N,': [723, 1666, 1705, 1740, 1818, 2318, 2698, 3533, 3579, 3600], 'Istanes': [724], 'C,': [725, 882, 1454, 1609, 1811, 1813, 2490, 2645, 2675], 'Sandberg': [726], 'WJ,': [727], 'Refsnes': [728], 'Schwarze': [730], 'P,': [731, 2622, 2641, 2712, 3639], 'Kruszewsky': [732], 'M': [733, 928, 1499, 1582, 1617, 1899, 2087, 2167, 2257, 2498, 2672], 'Brunborg': [735], 'G,': [736, 907, 1611, 1913, 3085, 3220, 3244, 3535, 3572], '2012.': [737, 892, 1248, 1341, 1462, 1586, 1621, 1961, 2360, 2437, 2536, 2718, 2749, 3175, 3508, 3650, 3844], 'Cytotoxicity': [738], 'genotoxicity': [740, 1382, 1472, 1592, 2211, 2597, 3029, 3271], 'effects': [741, 781, 1624, 1758, 2003, 2150, 2323, 2506], 'testicular': [746], '291,': [749], '65–': [750], '72.': [751], 'Bouwmeester': [752, 3506, 3648], 'H,': [753, 858, 891, 1636, 1716, 1915, 2461, 2811, 3381, 3507, 3649], 'Poortman': [754], 'Peters': [756, 3495, 3636], 'RJ,': [757, 3482], 'Wijma': [758], 'E,': [759, 761, 2959, 3486, 3595, 3799], 'Kramer': [760, 3485], 'Makama': [762], 'S,': [763, 1407, 1576, 1799, 1805, 2170, 2249, 2535, 2566, 3261, 3541], 'Puspitaninganindita': [764], 'K,': [765, 843, 1603, 1668, 1709, 1742, 1748, 1809, 2165, 2486, 2965, 2974, 3121, 3163, 3768], 'Marvin': [766, 3501], 'HJP,': [767, 3502], 'Peijnenburg': [768, 3503], 'ACM': [769], 'Hendriksen': [771, 3499, 3645], 'PJM,': [772, 3500], 'Characterization': [774, 3130], 'translocation': [776], 'whole-genome': [783], 'gene': [784], 'expression': [785], 'using': [786, 1028, 1474, 1519, 2365, 2544, 2753, 2782, 3735], 'vitro': [789, 1588, 2173, 2208, 2371, 3661], 'intestinal': [790, 3782], 'epithelium': [791], 'coculture': [792], 'model.': [793, 3665], 'ACS': [794, 2421, 2445, 3524], 'nano': [795, 2422], '5,': [796], '4091–': [797], '4103.': [798], 'Butler': [799], 'KS,': [800, 2562], 'Peeler': [801], 'DJ,': [802, 3167], 'Casey': [803], 'BJ,': [804], 'Dair': [805], 'BJ': [806], 'Elespuru': [808], 'RK,': [809], 'AgNPs:': [811], 'correlating': [812], 'nanoparticle': [813, 3849], 'cellular': [816], 'uptake': [817, 1426], 'genotoxicity.': [819], 'Mutagenesis': [820, 1402, 2732], '30,': [821, 878, 2992], '577–': [822], '591.': [823], 'Campomanes': [824], 'Vilches': [826], '(2010).': [827], 'Pearlescent': [828, 2774], 'pigment': [829, 2775], 'treatment': [831], 'confectionery;': [833], 'Patent': [834, 2785], 'N.:': [835], 'WO': [836], '2010100524': [837], 'A2.': [838], 'http://www.google.com/patents/WO2010100524A2?cl=en': [841], 'Cha': [842], 'HW,': [845, 3006], 'Choi': [846, 2964], 'YG,': [847], 'Lee': [848, 2966, 2970], 'MJ,': [849, 2584], 'Park': [850, 2195, 2956, 2973, 2995], 'JH,': [851], 'Chae': [852], 'HK,': [853], 'Ryu': [854], 'G': [855, 2315], 'Myung': [857], 'Comparison': [860], 'acute': [862, 2655], 'responses': [863, 2980, 3787], 'mice': [865, 2982, 3734], 'livers': [866], 'short-term': [868], 'nano-sized': [871], 'micro-sized': [873], 'particles.': [875], 'Biotechnology': [876], 'Letters': [877, 900, 1631], '1893–': [879], '1899.': [880], 'Beera': [881], 'Foldbjerga': [883], 'R,': [884, 980, 2455, 2558, 2582, 3635, 3637], 'Hayashib': [885], 'Sutherlandb': [887], 'DS': [888], 'Autrup': [890], 'Toxicity': [893, 3423], 'AgNPs—Nanoparticle': [895], 'ion?': [898], '208,': [901], '286–': [902], '292.': [903], 'Cotton': [904], 'FA,': [905], 'Wilkinson': [906], 'Murillo': [908], 'CA': [909], 'Bochmann': [911], '1999.': [913, 1141], 'Advanced': [914], 'Chemistry,': [916, 2551, 3858], 'sixth': [917], 'edition.': [918], 'John': [919, 2232], 'Sons,': [922, 2235], 'Inc.': [923, 2236], '(': [924, 2237], 'New': [925, 2238], 'York).': [926, 2239], 'Creasey': [927], 'Moffat': [930], 'DB,': [931], '1973.': [932], 'Deposition': [933], 'ingested': [935], 'rat': [939, 1782, 3207], 'kidney': [940], 'ages.': [943], 'Experientia': [944], '29,': [945], '326–': [946], '327.': [947], 'Danish': [948], 'Enviromental': [949, 2186], 'protection': [950], 'agency,': [951], 'Technical': [952, 3563], 'University': [953], 'Denmark': [955], '(DTU),': [956], '2013.': [957, 1503, 2205, 2261, 2319, 2623, 2796], 'Systemic': [958], 'absorption': [959, 1040], 'nanomaterials': [961], 'oral': [963, 1688, 2984, 3522], 'exposure.': [964, 3523], 'Part': [965, 2114, 3406, 3440], '"Better': [968], 'control': [969], 'nano"': [971], 'initiative': [972], '2012–2015.': [973], 'http://orbit.dtu.dk/files/59606121/Systemic%20absorption%20of%20nanomaterials%20by%20oral%20exposure%20978-87-93026-51-3.pdf': [976], 'Dijkstra': [977], 'Havinga': [979], 'Vonk': [981], 'RJ': [982], 'Kuipers': [984], 'F,': [985, 3671, 3690, 3836], '1996.': [986], 'Bile': [987], 'secretion': [988], 'cadmium,': [990], 'zinc': [992, 1123], 'copper': [994, 2008], 'rat.': [997, 2689], 'Involvement': [998], 'various': [1000], 'transport': [1001, 3373], 'systems.': [1002], 'Life': [1003], 'Sci': [1004], '59,': [1005], '1237–': [1006], '1246.': [1007], 'Ditter': [1008], 'IM,': [1009], 'Vitali': [1010], 'L,': [1011, 2311, 2492, 2580, 3123], 'Chaves': [1012], 'ES,': [1013], 'Maranhao': [1014], 'TA,': [1015], 'Borges': [1016], 'DLG,': [1017], 'de': [1018, 3001, 3013], 'Favere': [1019], 'VT': [1020], 'Curtius': [1022], 'AJ,': [1023], '2014.': [1024, 1227, 1276, 1419, 1642, 1847, 2001, 2091, 3129, 3269, 3580, 3807], 'Dispersive': [1025], 'liquid-liquid': [1026], 'microextraction': [1027], 'ammonium': [1029, 1125], 'O,O-diethyl': [1030], 'dithiophosphate': [1031], '(DDTP)': [1032], 'chelating': [1034], 'agent': [1035], 'graphite': [1037], 'furnace': [1038], 'atomic': [1039], 'spectrometry': [1041], 'determination': [1044, 1505, 1924], 'biological': [1048, 2443, 2505, 2511], 'samples.': [1049], 'Analytical': [1050, 2548], 'methods': [1051, 2209, 2778], '6,': [1052, 1659, 2013, 2447, 3526], '5584–': [1053], '5589.': [1054], 'Drake': [1055, 1547], 'PML': [1056], 'Hazelwood': [1058], 'KJ,': [1059], '2005.': [1060], 'Exposure-Related': [1061], 'Effects': [1063, 3774], 'Compounds:': [1068], 'A': [1069, 1121, 1638, 2115, 2122, 2285, 2792, 3840], 'Review.': [1070], 'Annals': [1072], 'Hygiene': [1075], '49,': [1076, 2953], '575–': [1077], '585.': [1078], '(European': [1080, 1105, 1145, 1171, 1205], 'Safety': [1082, 1107, 1147, 1173, 1207, 2866], 'Authority),': [1083, 1108, 1148, 1174, 1208], '2006.': [1084], 'Committee': [1089, 3299], 'related': [1090], 'uncertainties': [1092], 'dietary': [1094], 'assessment.': [1096, 3562], 'Journal': [1099, 1138, 1163, 1197, 1257, 1298, 1331, 1367, 1440, 1533, 1654, 1732, 1788, 1871, 2333, 2477, 2513, 2661, 2691, 2906, 2925, 3153, 3291, 3434, 3468, 3624, 3682, 3853], '2006,': [1100], '438,': [1101], '1–': [1102, 2081, 3338, 3756], '54.': [1103], '2011a.': [1109], 'substance,': [1118], 'zeolite': [1120], '(silver': [1122], 'sodium': [1124], 'alumino': [1126], 'silicate),': [1127], 'content': [1129, 3550], '2–5%,': [1130], 'contact': [1135], 'materials.': [1136], '2011;': [1139, 1164, 1198, 1332], '9(2):': [1140], '12': [1142], 'pp.': [1143, 1168, 1202, 1262, 1303, 1336, 1372], '2011b.': [1149], 'Comprehensive': [1154, 1191], 'Consumption': [1157, 1194], 'Database': [1158], 'Exposure': [1160], 'Assessment.': [1161], '9(3):': [1165, 1199], '2097,': [1166], '34': [1167], 'doi:10.2903/j.efsa.2011.209': [1169], '2011c.': [1175], 'Evaluation': [1176, 2068], 'FoodEx,': [1179], 'classification': [1182], 'system': [1183, 3458], 'development': [1187], 'Database.': [1195], '1970,': [1200], '27': [1201], 'doi:10.2903/j.efsa.2011.1970': [1203], 'Annual': [1210, 3110], 'report': [1211, 2592], 'Network': [1216], 'Risk': [1218, 1488], 'Assessmentt': [1219], 'nanotechnologies': [1221, 1323], 'Feed': [1225], 'Supporting': [1229], 'publication': [1230], '2014:': [1231], 'EN-762.': [1232], '11pp.': [1233], '(EFSA': [1237], 'Food),': [1247, 3327], 'submission': [1251], 'evaluations.': [1255], '2012;': [1258, 1368], '10(7):': [1259], '2760.': [1260], '60': [1261], 'doi:10.2903/j.efsa.2012.2760': [1263], 'Added': [1272], 'Statement': [1277], 'conceptual': [1280], 'framework': [1281], 'certain': [1287, 2070], 're-evaluated': [1290], 'under': [1291], 'Regulation': [1293], '(EU)': [1294], 'No': [1295], '257/2010.': [1296], '2014;': [1299], '12(6):': [1300], '3697,': [1301], '11': [1302], 'doi:10.2903/j.efsa.2014.3697': [1304], 'Committee,': [1307, 1340, 1354], 'application': [1319], 'nanoscience': [1321], 'feed': [1328, 3552], 'chain.': [1329], '9(5):': [1333], '2140.': [1334], '36': [1335], 'doi:10.2903/j.efsa.2011.2140.': [1337], 'selected': [1344], 'default': [1345], 'values': [1346], 'Panels': [1356], 'Units': [1358], 'absence': [1361], 'actual': [1363], 'measured': [1364], 'data.': [1365], '10(3):': [1369], '2579,': [1370], '32': [1371], 'doi:10.2903/j.efsa.2012.2579': [1373], 'Eliopoulos': [1374], 'P': [1375], 'Mourelatos': [1377], 'D,': [1378], '1998.': [1379, 3422], 'Lack': [1380], 'iodide': [1385], 'SCE': [1388], 'assay': [1389], 'vitro,': [1391], 'vivo,': [1393], 'Ames/microsome': [1397], 'test.': [1398], 'Teratogenesis,': [1399], 'Carcinogenesis,': [1400], '18,': [1403], '303–': [1404], '308.': [1405], 'Enamorado': [1406], 'Abril': [1408], 'JM,': [1409, 1418, 2494], 'Delgado': [1410], 'A,': [1411, 1502, 1578, 1585, 1605, 1613, 1670, 1672, 1685, 1711, 1744, 1801, 1807, 1846, 2251, 2255, 2313, 2741, 3156, 3174, 3407, 3441, 3598], 'Mas': [1412], 'Polvillo': [1414], 'O': [1415, 2532], 'Quintero': [1417], 'Implications': [1420], 'tomato': [1428], '25': [1430], 'trace-elements': [1431], 'phosphogypsum': [1434], 'amended': [1435], 'soil': [1436], 'SW': [1438], 'Spain.': [1439], 'Hazardous': [1442], 'Materials': [1443, 2515], '266,': [1444], '122–': [1445, 3378], '131.': [1446], 'Flower': [1447], 'NAL,': [1448], 'Brabu': [1449], 'B,': [1450, 1641, 2517, 2528, 3383, 3806, 3838], 'Revathy': [1451], 'Gopalakrishnan': [1453], 'Raja': [1455], 'SVK,': [1456], 'Murugan': [1457], 'SS': [1458], 'Kumaravel': [1460], 'T,': [1461, 2245, 2359, 2526, 2574, 2578, 2650, 2717, 3165, 3169], 'Characterisation': [1463], 'synthesised': [1465], 'potentials': [1473], 'alkaline': [1476], 'comet': [1477], 'assay.': [1478, 2373], 'Mutation': [1479, 1595, 2374, 2613, 2819], 'Research': [1480, 1596, 2375, 2614, 2820, 3742], '742,': [1481], '61–': [1482], '65.': [1483, 2617], 'Federal': [1485], 'Institute': [1486], 'Assessment': [1489], '(BfR),': [1490], '2009.': [1491, 2171], 'Nr.': [1493], '024/2010.': [1494], 'http://www.bfr.bund.de/cm/216/bfr_raet.': [1497], 'Fukushima': [1498, 2565], 'Chatt': [1501], 'Rapid': [1504], 'cultivated': [1509], 'Japanese': [1510, 1516], 'South': [1512], 'Korean': [1513, 1942], 'oysters': [1514, 1518], 'rock': [1517], '24.6-s': [1521], 'neutron': [1522], 'activation': [1523], 'product': [1524], '110Ag': [1525], 'estimation': [1527], 'average': [1530], 'daily': [1531], 'intake.': [1532], 'Radioanalytical': [1535], 'Nuclear': [1537], 'Chemistry': [1538, 2481, 2516, 2762, 3628], '296,': [1539], '563–': [1540], '571.': [1541], 'Furchner': [1542], 'JE,': [1543], 'Richmond': [1544], 'CR': [1545], 'GA,': [1548], '1968.': [1549], 'Comparative': [1550, 3270], 'metabolism': [1551, 2009], 'radionuclides': [1553], 'mammals-IV.': [1555], 'Retention': [1556], 'silver-110m': [1558], 'mouse,': [1561], 'rat,': [1562], 'monkey,': [1563], 'dog.': [1565], 'Physics': [1567], '15,': [1568, 1875], '505–': [1569], '514.': [1570], 'Ghosh': [1571, 2671], 'Manivannan': [1573], 'Sinha': [1575], 'Chakraborty': [1577], 'Mallick': [1579], 'SK,': [1580], 'Bandyopadhyay': [1581], 'Mukherjee': [1584], 'In': [1587, 2172], 'vivo': [1591, 1765], '749,': [1597], '60–': [1598], '69.': [1599], 'Gromadzka-Ostrowska': [1600], 'Dziendzikowskaa': [1602], 'Lankoff': [1604, 2254], "Dobrzyn'skad": [1606], 'Instanese': [1608], 'Brunborge': [1610], 'Gajowikd': [1612], 'Radzikowskad': [1614], 'Wojewódzkab': [1616], 'Kruszewskib': [1619], 'epididymal': [1626], 'sperm': [1627], 'rats.': [1629, 1697, 2011, 3051, 3234, 3793], '214,': [1632], '251–': [1633], '258.': [1634], 'Haase': [1635], 'Fahami': [1637], 'Mahltig': [1640], 'Impact': [1643], 'innate': [1651], 'immune': [1652, 3786], 'Biomedical': [1656], 'Nanotechnology,': [1657], '10,': [1658, 3591], '1146–': [1660], '1156.': [1661], '(Only': [1662], 'abstract': [1663], 'available).': [1664], 'Hadrup': [1665, 1704, 1739], 'Loeschner': [1667, 1708, 1741], 'Bergstroem': [1669], 'Wilcks': [1671], 'Gao': [1673], 'X,': [1674, 2309, 2704, 3709, 3715], 'Vogel': [1675], 'U,': [1676], 'Frandsen': [1677, 1715], 'HL,': [1678], 'Larsen': [1679, 1712, 1749], 'EH,': [1680], 'Lam': [1681, 1706, 1752], 'HR': [1682], 'Mortensen': [1684, 1710, 1743], '2012a.': [1686], 'Subacute': [1687], 'investigation': [1690], 'nanoparticulate': [1692, 1760, 2751], 'Archives': [1698, 2950], '86,': [1701], '543–': [1702], '551.': [1703], 'HR,': [1707, 1753, 2194], 'EH': [1713, 1750], '2012b.': [1717], 'Nanoparticulate': [1718], 'increases': [1720], 'uric': [1721], 'acid': [1722], 'allantoin': [1724], 'excretion': [1725], 'rats,': [1727], 'identified': [1729], 'metabolomics.': [1731], '32,': [1736, 3033], '929–': [1737], '933.': [1738], 'Sharma': [1745], 'AK,': [1746, 3037], 'Qvortrup': [1747], '2012c.': [1754], 'neurotoxic': [1757], 'vitro.': [1768], 'Neurotoxicology': [1769], '33,': [1770], '416–': [1771], '423.': [1772], 'Ham': [1773], 'KN': [1774], 'Tange': [1776], 'JD,': [1777], '1972.': [1778, 3691], 'deposition': [1780, 3453, 3693], 'glomerular': [1783, 3697], 'basement': [1784, 3678, 3698], 'membrane.': [1785, 3699], 'Australian': [1787], 'Experimental': [1790, 1975, 2887, 2915, 2934, 3200, 3209, 3673, 3684], 'Biology': [1791], 'Medical': [1793, 2134, 2297, 2664, 3304], 'Science': [1794, 1874, 2187, 2396, 2665, 3189], '50,': [1795], '423–': [1796], '434.': [1797], 'Hackenberg': [1798], 'Scherzed': [1800], 'Kessler': [1802], 'Hummel': [1804], 'Technau': [1806], 'Froelich': [1808], 'Ginzkey': [1810], 'Koehler': [1812], 'Hagen': [1814], 'R': [1815], 'Kleinsasser': [1817], 'nanoparticles:': [1821, 2471], 'damage,': [1825], 'functional': [1828], 'impairment': [1829], 'human': [1831, 2183, 2272, 3186, 3275, 3662], 'mesenchimal': [1832], 'stem': [1833], 'letters': [1836], '201,': [1837], '27–': [1838], '33.': [1839], 'Hamilton': [1840], 'RF,': [1841], 'Buckingham': [1842], 'S': [1843, 2407, 2647], 'Holian': [1845], 'effect': [1849, 3018], 'Ag': [1853], 'nanosphere': [1854], 'macrophage': [1857], 'cell': [1858, 1863], 'models': [1859], 'lung': [1861], 'epithelial': [1862], 'lines': [1864], 'dependent': [1866], 'dissolution.': [1869], 'International': [1870, 2805], 'Molecular': [1873, 2731, 3052, 3211], '6815–': [1876], '6830.': [1877], 'Holler': [1878], 'JS,': [1879], 'Nordberg': [1880], 'GF': [1881, 1895], 'Fowler': [1883], 'BA,': [1884], '2007.': [1885, 2469], 'Silver.': [1886, 3319], 'In:': [1887], 'Handbook': [1888], 'toxicology': [1891], 'metals.': [1893], 'Eds': [1894], 'Nordberg,': [1896, 1900], 'BA': [1897], 'Fowler,': [1898], 'LT': [1901], 'Friberg.': [1902], 'Third,': [1903], 'Academic': [1904], 'Press,': [1905], 'Elsevier,': [1906], 'UK,': [1907], '809–': [1908], '814.': [1909], 'Hu': [1910], 'Q,': [1911], 'Yang': [1912], 'Li': [1914, 2308, 2341, 3382, 3718, 3723], 'Tai': [1916], 'X': [1917], 'Yin': [1919, 3712], '2004.': [1921], 'seven': [1926], 'transition': [1927], 'metal': [1928], 'water': [1931, 3072], 'microcolumn': [1935], 'high-performance': [1936], 'liquid': [1937], 'chromatography.': [1938], 'Bulletin': [1939, 1973], 'Chemical': [1943, 2159, 2225, 2438], 'Society': [1944, 3114], '25,': [1945], '694–': [1946], '698.': [1947], 'Ilyechova': [1948, 1982], 'EY,': [1949, 1983], 'Babich': [1950, 1988], 'PS,': [1951, 1989], 'Barishpolets': [1952], 'VV,': [1953], 'Tsymbalenko': [1954, 1996], 'NV,': [1955], 'Puchkova': [1956, 1999], 'LV': [1957], 'Sapronov': [1959], 'NS,': [1960], 'Development': [1962], 'laboratory': [1964], 'rats': [1965, 2847, 2895, 2946, 3095, 3431, 3519], 'receiving': [1966], 'silver-enriched': [1967], 'rations': [1968], 'long': [1971, 2268, 2901], 'time.': [1972, 2904], 'Biololy': [1976], 'Medicine': [1978], '153,': [1979], '378–': [1980], '384.': [1981], 'Saveliev': [1984], 'AN,': [1985, 1987], 'Skvortsov': [1986], 'Zatulovskaia': [1990], 'YA,': [1991], 'Pliss': [1992], 'MG,': [1993], 'Korzhevskii': [1994], 'DE,': [1995, 3484], 'NV': [1997], 'LV,': [2000], 'Metallomics': [2012], '1970–': [2014], '87.': [2015], 'Jackson': [2016], 'FJ,': [2017], 'Read': [2018], 'JI': [2019], 'Lucas': [2021, 2534], 'BE,': [2022], '1980.': [2023], 'Determination': [2024], 'total': [2026], 'chromium,': [2027], 'cobalt,': [2028], 'foodstuffs': [2032], 'flame': [2034], 'atomic-absorption': [2035], 'spectrophotometry.': [2036], 'Analyst': [2037], '(London)': [2038], '105,': [2039], '359–': [2040], '370.': [2041], 'JECFA': [2042], '(Joint': [2043], 'FAO/WHO': [2044], 'Comittee': [2046, 3325, 3333], 'Additives),': [2049], '1977.': [2050, 3086], 'Summary': [2051], 'Toxicological': [2053, 2125, 2288, 3309], 'Data': [2054, 3310], 'Certain': [2056], 'Additives,': [2058], 'Twenty-first': [2059, 2073], 'No.': [2061], '12,': [2062, 2482], 'http://www.inchem.org/documents/jecfa/jecmono/v12je19.htm': [2065], 'JECFA,': [2066], '1978.': [2067], 'additives,': [2072], 'report.': [2074], 'World': [2075], 'Organ': [2077], 'Tech': [2078], 'Rep': [2079], 'Ser,': [2080], '41.': [2082], 'http://www.ncbi.nlm.nih.gov/pubmed/96612': [2085], 'Jokar': [2086], 'Rahman': [2089], 'RA,': [2090, 2350], 'ion': [2095], 'migration': [2096], 'melt-blended': [2098], 'layered-deposited': [2100], 'polyethylene': [2102], 'nanocomposite': [2103], 'into': [2104, 3073, 3399], 'simulants': [2106], 'apple': [2108], 'juice.': [2109], 'Contaminants,': [2113], '31,': [2116, 2763, 2821], '734–': [2117], '742.': [2118], 'Lansdown': [2119, 2282], 'ABG,': [2120], '2010.': [2121, 2284, 2384, 2411, 2975, 3542], 'Pharmacological': [2123, 2138, 2286, 2301], 'Profile': [2126, 2289], 'Antimicrobial': [2131, 2294], 'Agent': [2132, 2295], 'Devices.': [2135, 2298], 'Advances': [2136, 2299], 'Sciences,': [2139, 2302], 'Article': [2140, 2303], 'ID': [2141, 2304], '910686,': [2142, 2305], '16': [2143, 2306], 'pages.': [2144, 2307], 'Lappas': [2145], 'CM,': [2146], 'immunomodulatory': [2149], 'titanium': [2152], 'dioxide': [2153], 'Nanoparticles.': [2156], '85,': [2161], '78–': [2162], '83.': [2163], 'Kawata': [2164], 'Osawa': [2166], 'Okabe': [2169], 'noncytotoxic': [2179], 'doses': [2180], 'HepG2': [2182, 3277], 'hepatoma': [2184], 'Technology': [2189, 2398], '43,': [2190], '6046–': [2191], '6051.': [2192], 'Kim': [2193, 2962], 'YJ,': [2196], 'Shin': [2197], 'da': [2198], 'Oh': [2200], 'SM': [2201], 'Chung': [2203], 'KH,': [2204], 'Appropriate': [2206], 'testing': [2212], '28,': [2219, 3408], 'e2013003.': [2220], 'Kirk-Othmer': [2221], '(2006).': [2222], 'Encyclopedia': [2223], 'Technology,': [2226], 'fifth': [2227], 'edition,': [2228], '22,': [2229], '636–': [2230], '691.': [2231], 'Kruszewski': [2240], 'Gradzka': [2242], 'I,': [2243, 3644], 'Bartlomiejczyk': [2244], 'Chwastowska': [2246], 'Sommer': [2248], 'Grzelak': [2250], 'Zuberek': [2252], 'Dusinska': [2256], 'Wojewodzka': [2259], 'Oxidative': [2262], 'corresponds': [2265], 'term': [2269], 'survival': [2270], 'cells': [2273, 3281], 'treated': [2274], 'Lett': [2278], '219,': [2279], '151–': [2280, 3082], '159.': [2281], 'AB,': [2283], 'Xu': [2310], 'Shao': [2312], 'Wu': [2314, 3386], 'Hanagata': [2317], 'Cytotoxic': [2320], 'genotoxic': [2322], 'AgNPs': [2325, 2363, 2799, 3514], 'primary': [2327], 'Syrian': [2328], 'hamster': [2329], 'embryo': [2330], '(SHE)': [2331], 'Nanoscience': [2335], 'Nanotechnology': [2337], '13,': [2338], '161–': [2339, 3475], '170.': [2340], 'Chen': [2343, 2347, 2358, 2454, 2701, 2716, 3389], 'DH,': [2344], 'Yan': [2345], 'Mittelstaedt': [2349], 'Zhang': [2351, 2699, 3714, 3833], 'Biris': [2353, 2709], 'AS,': [2354, 2710, 3421], 'Heflich': [2355], 'RH': [2356], 'Genotoxicity': [2361], 'evaluated': [2364, 3282], 'Ames': [2367], 'test': [2368], 'micronucleus': [2372, 3289], '745,': [2376], '4–': [2377], '10.': [2378], 'Liu': [2379, 2402, 2426, 2430], 'J': [2380, 3217, 3241], 'Hurt': [2382, 2409, 2435], 'RH,': [2383, 2410, 2436], 'Ion': [2385], 'Release': [2386], 'Kinetics': [2387], 'Particle': [2389], 'Persistence': [2390], 'Aqueous': [2392], 'Nano-Silver': [2393], 'Colloids.': [2394], '44,': [2399], '2169–': [2400], '2175.': [2401], 'Sonshine': [2404], 'DA,': [2405, 2564], 'Shervani': [2406], 'Controlled': [2412], 'biologically': [2415], 'active': [2416], 'nanosilver': [2419, 2441, 3273], 'surfaces.': [2420], '4,': [2423], '6903–': [2424], '6913.': [2425], 'Wang': [2428, 3708, 3720], 'Z,': [2429, 3717, 3834], 'FD,': [2431], 'Kane': [2432], 'AB': [2433], 'transformations': [2439], 'I': [2442], 'environments.': [2444], 'nano,': [2446], '9887–': [2448], '9899.': [2449], 'Lok': [2450], 'C-N,': [2451], 'Ho': [2452], 'C-M,': [2453, 2468], 'He': [2456], 'Q-Y,': [2457], 'Yu': [2458], 'W-Y,': [2459], 'Sum': [2460], 'Tam': [2462], 'PK-H,': [2463], 'Chiu': [2464], 'J-F': [2465], 'Che': [2467], 'partial': [2472], 'oxidation': [2473], 'antibacterial': [2475], 'activities.': [2476], 'Biological': [2479, 3548, 3739], '527–': [2483], '534.': [2484], 'Loza': [2485], 'Diendorf': [2487], 'Sengstock': [2489], 'Ruiz-Gonzalez': [2491], 'Gonzalez-Calbet': [2493], 'Vallet-Regi': [2495], 'Kollerb': [2497], 'Epple': [2500], 'M.': [2501], 'dissolution': [2503], 'media.': [2512], '2,': [2518], '1634–': [2519], '1643.': [2520], 'Lozano': [2521], 'O,': [2522], 'Mejia': [2523], 'Tabarrant': [2525], 'Masereel': [2527], 'Dogne': [2529], 'J-M,': [2530], 'Toussaint': [2531], 'Quantification': [2537], 'aqueous': [2541], 'matrices': [2543], 'Particle-Induced': [2545], 'X-ray': [2546], 'Emission.': [2547], 'Bioanalytical': [2550], '403,': [2552], '2835–': [2553], '2841.': [2554], 'MacGregor': [2555], 'JT,': [2556], 'Frotschl': [2557], 'White': [2559], 'PA,': [2560], 'Crump': [2561], 'Eastmond': [2563], 'Guerard': [2567], 'Hayashi': [2569], 'Soeteman-Hernandez': [2571], 'LG,': [2572], 'Kasamatzu': [2573], 'Levy': [2575], 'DD,': [2576], 'Morita': [2577], 'Muller': [2579], 'Schoeny': [2581], 'Schuler': [2583], 'Thybaud': [2585], 'V': [2586, 3537], 'Johnson': [2588], 'GE,': [2589], 'IWGT': [2591], 'quantitative': [2594], 'approaches': [2595], 'I.': [2600], 'Methods': [2601], 'metrics': [2603], 'defining': [2605], 'exposure-response': [2606], 'relationship': [2607], 'points': [2609], 'departure': [2611], '(PoDs).': [2612], '783,': [2615], '55–': [2616], 'Maillard': [2618], 'JY': [2619], 'Hartemann': [2621], 'antimicrobial:': [2627], 'facts': [2628], 'knowledge.': [2632], 'Critical': [2633], 'Reviews': [2634], 'Microbiology': [2636], '39,': [2637], '373–': [2638], '383.': [2639], 'Maneewattanapinyo': [2640], 'Banlunara': [2642], 'W,': [2643, 2706], 'Thammacharoen': [2644], 'Ekgasit': [2646], 'Kaewamatawong': [2649], 'An': [2652], 'colloidal': [2658], 'Veterinary': [2663], '73,': [2666], '1417–': [2667], '1423.': [2668], 'Matuk': [2669], 'McCulloch': [2674], '1981.': [2676], 'Distribution': [2677, 3726], 'eyes': [2682, 2893], 'plasma': [2684, 3150], 'proteins': [2685], 'albino': [2688], 'Canadian': [2690], 'Ophthalmology': [2693], '16,': [2694], '145–': [2695], '150.': [2696], 'Mei': [2697], 'Guo': [2703], 'Ding': [2705], 'Ali': [2707], 'SF,': [2708], 'Rice': [2711], 'Moore': [2713], 'MM': [2714], 'nanoparticle-induced': [2720, 3045], 'mutations': [2721], 'oxidative': [2723, 3046], 'stress': [2724], 'mouse': [2726], 'lymphoma': [2727], '53,': [2733, 3442], '409–': [2734], '419.': [2735], 'Mitrano': [2736], 'DM,': [2737], 'Lesher': [2738], 'EK,': [2739], 'Bednar': [2740], 'Monserud': [2742], 'Higgins': [2744], 'CP': [2745], 'Ranville': [2747], 'JF,': [2748], 'Detecting': [2750], 'single-particle': [2754], 'inductively': [2755, 3148], 'coupled': [2756, 3101, 3146, 3149], 'plasma-mass': [2757], 'spectrometry.': [2758, 3152], '115–': [2764], '121.': [2765], 'Myers': [2766], 'GD,': [2767], 'Plodzien': [2768], 'JR': [2769], 'Otto': [2771], 'LH,': [2772], '2008;': [2773], 'composition': [2776], 'making': [2780], 'same.': [2784], 'N.': [2786], 'WO/2008/076902.': [2787], 'https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2008076902.': [2790], 'Nawrocka': [2791], 'Ciesla': [2794], 'Influence': [2797], 'components': [2802], 'wheat.': [2804], 'Agrophysics': [2806], '27,': [2807], '49–': [2808], '55.': [2809], 'Nishioka': [2810], '1975.': [2812, 3328], 'Mutagenic': [2813], 'Activities': [2814], 'Metal-Compounds': [2816], 'Bacteria.': [2818], '185–': [2822, 3831], '189.': [2823], '<Go': [2826], 'ISI>://A1975AC94200007.': [2828], 'NTP,': [2829], '2002.': [2830], 'Developmental': [2831], 'acetate': [2836], '(CAS': [2837], 'NO.': [2838], '563-63-3)': [2839], 'adminstered': [2840], 'gavage': [2842], 'sprague': [2844], '-Dawley': [2845], '(CD)': [2846], 'gestational': [2849], 'days': [2850], '6': [2851], 'through': [2852], '19.': [2853], 'NTP/NIEHS': [2854], 'Contract': [2855], 'NO.:': [2856, 2860], 'N01-ES-65405': [2857], 'NTP': [2858], 'TER-20–001.': [2861], 'OECD': [2862], 'Environment,': [2863], 'Publications.': [2867], 'Series': [2868], 'manufactured': [2873], 'nanomaterials.': [2874, 3589], 'N.53.': [2875], 'Dossier': [2876], 'nanoparticles.': [2879], 'http://www.oecd.org/chemicalsafety/nanosafety/dossiers-and-endpoints-testing-programme-manufactured-nanomaterials.htm': [2883], 'Olcott': [2884, 2912, 2931], 'CT,': [2885, 2913, 2932], '1947.': [2886], 'Argyrosis': [2888, 2916, 2935], '3.': [2889], 'Pigmentation': [2890], 'following': [2896], 'ingestion': [2897], 'during': [2900], 'periods': [2902], 'American': 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