Scientific Opinion on a request for a review of a scientific publication concerning the zoonotic potential of ovine scrapie prions

Name: Work Video:
Duration: 3 min 30 s
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'wishes': [128], 'to': [129, 183, 208, 230, 253, 354, 382, 448, 455, 519, 528, 708, 739, 941, 995, 1041, 1185, 1442, 1687, 1771, 1823, 1861, 2118, 2215, 2251, 2283, 2339, 2381, 2420, 2535, 2572, 2712, 2787, 2989, 3066, 3092, 3442, 3690, 3698, 3792, 3824, 3917, 3949, 4092, 4158, 4273], 'thank': [130], 'members': [132], 'Working': [135], 'Group': [136], 'Zoonotic': [138, 2209], 'scrapie:': [140, 3401], 'Christine': [141], 'Hoffmann': [142, 2881, 3732], 'Fast,': [143], 'Romolo': [144], 'Nonno,': [145], 'Spiropoulos,': [151], 'Will': [154, 1283, 1306, 1744, 2531, 3506, 4030], 'preparatory': [157], 'work': [158], 'output': [162], 'hearing': [165], 'expert:': [166], 'Olivier': [167], 'Andreoletti': [168, 1116, 1935, 2359, 3386], 'staff': [171], 'Pietro': [173], 'Stella': [174], 'Angel': [176], 'Ortiz': [177], 'Pelaez': [178], 'support': [181], 'provided': [182], 'output.': [186], 'Adoption': [187], 'date:': [188, 193], '9': [189, 2835], 'July': [190], 'Published': [192], '5': [194], 'Question': [197], 'number:': [198], 'EFSA-Q-2015-00048': [199], 'On': [200], 'from:': [202], 'European': [203, 548, 2781], 'Commission': [204, 2782], 'AboutPDF': [205], 'ToolsExport': [206], 'citationAdd': [207], 'favoritesTrack': [209], 'citation': [210], 'ShareShare': [211], 'Give': [212], 'accessShare': [213, 216], 'full': [214], 'text': [215], 'full-text': [217, 232, 256], 'accessPlease': [218], 'our': [220], 'Terms': [221, 244], 'Conditions': [223, 246], 'Use': [225, 991], 'check': [227], 'box': [228], 'below': [229, 252], 'share': [231, 254], 'version': [233, 257], 'article.I': [235], 'have': [236, 379, 487], 'read': [237], 'accept': [239], 'Wiley': [241], 'Online': [242], 'Library': [243], 'UseShareable': [248], 'LinkUse': [249], 'link': [251, 466], 'article': [260], 'with': [261, 446, 929, 1232, 1614, 1733, 1832, 3197, 3653, 3682], 'your': [262], 'friends': [263], 'colleagues.': [265], 'Learn': [266], 'more.Copy': [267], 'URL': [268], 'Share': [269], 'linkShare': [271], 'onFacebookTwitterLinkedInRedditWechat': [272], 'Abstract': [273], 'factors': [275, 486, 2488], 'that': [276, 334, 348, 367, 376, 390, 444, 516, 1774], 'modulate': [277, 1433], 'transmissibility': [279, 3235], 'Transmissible': [281, 998, 1680, 2791, 3814], 'Spongiform': [282, 999, 1645, 1681, 2723, 2792, 3684, 3790], 'Encephalopathies': [283, 1682, 2793], '(TSE)': [284], 'approaches': [287], 'study': [290, 372, 2456, 3526], 'their': [292, 1318], 'are': [295, 352, 423, 509, 517, 2115], 'reviewed.': [296], 'paper': [298, 327], "'": [299, 406], 'Evidence': [300, 1938, 3230], "prions'": [307], 'Cassard': [309, 1906], 'et': [310, 1582], 'al.': [311], '(2014)': [312], 'is': [313, 365, 899, 927, 1778, 2969], 'scientifically': [314], 'appraised,': [315], 'focussing': [316], 'experimental': [319, 1388, 1833], 'design,': [320], 'results': [322, 369], 'conclusions.': [325], 'provides': [328], 'evidence': [329, 389, 432, 462, 476], 'in': [330, 341, 419, 425, 546, 569, 601, 653, 802, 805, 830, 860, 896, 901, 1081, 1226, 1435, 1478, 1576, 1865, 1897, 1972, 2038, 2171, 2424, 2433, 2795, 2828, 2856, 2866, 2901, 2926, 2953, 3060, 3144, 3297, 3362, 3403, 3439, 3462, 3488, 3518, 3565, 3588, 3687, 3741, 3750, 3887, 3912, 3987, 4089, 4124, 4151], 'laboratory': [332, 3053, 3829], 'experiment': [333], 'some': [335, 452], 'Classical': [336, 468, 905, 939, 1050], 'isolates': [338], 'can': [339, 392], 'propagate': [340, 643], 'humanised': [342], 'transgenic': [343, 654, 1187, 1229, 1853, 3363, 4277], 'mice': [344, 655, 898, 1186, 1230, 1543, 1772, 1854], 'produce': [346], 'second': [350, 770], 'passage': [351], 'similar': [353], 'those': [355], 'causing': [356], 'one': [357], 'form': [358, 856], 'sporadic': [360, 649, 1313, 1357, 1618, 2490, 3056, 3485, 4125], 'Creutzfeldt-Jakob': [361, 562, 677, 1078, 1314, 1358, 1572, 1619, 2458, 2491, 2551, 3057, 3087, 3437, 3486, 3516, 3805, 4087, 4126, 4199], 'disease': [362, 835, 1039, 1079, 1315, 1359, 1896, 2418, 2459, 2755, 3015, 3058, 3088, 3438, 3487, 3517, 4052, 4056, 4088, 4127, 4269], '(sCJD).': [363], 'It': [364], 'concluded': [366], 'from': [370, 499, 534, 538, 564, 865, 904, 1360, 2335, 2779, 2987, 3064, 3206, 3359, 3677, 3990], 'raise': [373], 'possibility': [375, 493], 'be': [383, 456, 506], 'zoonotic,': [384, 457], 'but': [385, 458], 'do': [386], 'not': [387, 460, 478, 2116], 'provide': [388, 461], 'transmission': [391, 703, 741, 864, 937, 1296, 1319, 1835, 3091, 3787, 3948, 4336], 'or': [393, 414, 469, 648, 1683, 2823], 'does': [394, 459, 477], 'take': [395], 'place': [396], 'under': [397], 'field': [398, 3295], 'conditions.': [399], 'conclusions': [401, 442], '2011': [404], 'ECDC-EFSA': [405], 'Joint': [407, 2816], 'any': [411, 2820], 'possible': [412, 2821], 'epidemiological': [413, 2822], 'molecular': [415, 1007, 2824, 3894], 'association': [416, 2825], 'between': [417, 467, 2826], 'TSEs': [418, 2827], 'animals': [420, 2829], "humans'": [422], 'reviewed': [424], 'light': [427], 'new': [430, 834, 855], 'available': [433], 'since': [434], 'its': [435, 2573], 'publication.': [436], 'This': [437], 'supports': [438], 'strengthens': [440], 'opinion': [445], 'regard': [447], 'animal': [453, 525, 799, 1672, 2180], 'TSE': [454, 526, 1043, 1700, 2422], 'causal': [465], 'Atypical': [470, 2331, 2951, 3356, 3985, 4340], 'human': [473, 657, 858, 1189, 1227, 1670, 2178, 3095, 3145, 3918, 4050, 4335], 'TSE.': [474], 'Current': [475], 'establish': [479], 'link,': [481], 'no': [483, 2970], 'consistent': [484], 'risk': [485, 2487, 2549, 2789, 4337], 'been': [488], 'identified': [489], 'sCJD.': [491], 'scrapie-related': [495], 'public': [496], 'health': [497], 'risks': [498], 'consumption': [501], 'products': [504, 536], 'cannot': [505], 'assessed.': [507], 'Recommendations': [508], 'formulated': [510], 'further': [512], 'studies': [513, 2170, 2539], 'data': [515, 1575, 3063], 'needed': [518], 'investigate': [520], 'estimate': [529], 'amount': [531], 'infectivity': [533, 1860], 'TSE-infected': [535], 'sourced': [537], 'small': [539, 3298], 'ruminants': [540, 3299], 'entering': [542], 'food': [544], 'chain': [545], 'Union.': [549], 'References': [550], 'Ahmad': [551], 'A,': [552, 594, 720, 815, 982, 1120, 1171, 1202, 1210, 1338, 1342, 1344, 1351, 1416, 1462, 1520, 1637, 1712, 1753, 1757, 2194, 2268, 2475, 2519, 2739, 2884, 3109, 3170, 3273, 3275, 3330, 3340, 3347, 3449, 3451, 3635, 3725, 3733, 3777, 3964, 4008, 4035, 4070, 4104], 'Rao': [553], 'F': [554], 'Aieshah': [556], 'S,': [557, 624, 668, 884, 978, 1212, 1245, 1497, 1565, 1714, 1763, 1919, 2097, 2228, 2264, 2306, 2314, 2316, 2350, 2565, 2659, 2949, 3138, 3334, 3413, 3415, 3421, 3509, 3601, 3629, 3852, 4192, 4321], '2014.': [558, 1937, 2485, 2849], 'Two': [559], 'cases': [560, 682, 1001, 1653, 3296, 3358, 3461], 'Disease': [563], 'an': [565, 1147, 2384, 2612, 3198, 4339], 'ongoing': [566], 'dementia': [567], 'registry': [568], 'Pakistan.': [570], 'Journal': [571, 868, 944, 1157, 1488, 1735, 1837, 1869, 2464, 2498, 2619, 2690, 2802, 2833, 2871, 2906, 3020, 3303, 3367, 3466, 3530, 3710, 3993, 4058, 4130, 4208, 4216, 4280], 'Pakistan': [574], 'Medical': [575, 1704, 2502, 3156, 3820], 'Association,': [576], '64,': [577], '705–': [578], '707.': [579], 'Akesson': [580], 'CP,': [581], 'Press': [582, 781], 'CM,': [583, 960, 1017, 2400], 'Tranulis': [584, 1092], 'MA,': [585, 718, 751, 787, 813, 841, 1093, 1428, 1468, 1796, 2647], 'Jeffrey': [586, 2670, 3932], 'M,': [587, 589, 622, 675, 722, 878, 880, 1027, 1063, 1136, 1514, 1665, 1800, 1989, 2320, 2402, 2445, 2513, 2517, 2523, 2629, 2655, 2669, 2671, 2700, 2707, 2880, 2886, 2914, 3119, 3133, 3277, 3426, 3599, 3637, 3729, 3779, 3856, 3900, 3927, 3933, 4006, 4010, 4018, 4020, 4076, 4190], 'Aleksandersen': [588], 'Landsverk': [590], 'T': [591], 'Espenes': [593, 1094], '2012.': [595, 757, 1099, 1606, 1885, 2113, 2414, 2533, 2749, 3427, 3813, 3883, 4094], 'Phenotypic': [596], 'characterization': [597, 1726, 2896], 'cells': [599], 'participating': [600], 'transport': [602], 'prion': [604, 651, 658, 761, 800, 1105, 1145, 1190, 1259, 1440, 1545, 1999, 2058, 2119, 2152, 2249, 2281, 2570, 2616, 2754, 2930, 3018, 3142, 3261, 3266, 3589, 3616, 3650, 3744, 3885, 3919, 3947, 4051, 4156], 'protein': [605, 762, 1441, 1826, 2059, 2571, 2617, 2931, 3143, 3590, 3651, 4157], 'aggregates': [606], 'across': [607, 3265], 'intestinal': [609], 'mucosa': [610], 'sheep.': [612], 'Prion,': [613, 808, 2218, 2254], '6,': [614], '261–': [615], '275.': [616], 'Asante': [617], 'EA,': [618], 'Linehan': [619, 3116], 'JM,': [620, 1909, 2200, 2234, 3328, 3377, 3773], 'Desbruslais': [621, 3598], 'Joiner': [623, 3600, 3628], 'Gowland': [625, 3604], 'I,': [626, 1098, 1495, 1502, 1716, 1749, 1921, 3338, 3605, 4022, 4303], 'Wood': [627], 'AL,': [628, 1076, 4250], 'Welch': [629], 'J,': [630, 639, 728, 889, 922, 989, 1034, 1528, 1588, 1590, 1718, 1759, 1951, 1983, 2007, 2028, 2093, 2101, 2112, 2138, 2142, 2196, 2230, 2232, 2260, 2348, 2413, 2510, 2595, 2661, 3036, 3117, 3131, 3168, 3215, 3245, 3320, 3352, 3391, 3607, 3642, 3673, 3738, 3784, 3935, 3972, 4029, 4240], 'Hill': [631, 2146, 3596, 3626], 'AF,': [632, 2147, 3597, 3627], 'Lloyd': [633], 'SE,': [634], 'Wadsworth': [635, 3638], 'JDF': [636, 3639], 'Collinge': [638, 2137, 3606, 3641], '2002.': [640, 1666, 1724], 'BSE': [641, 705, 903, 1782, 2332, 2428, 2725], 'as': [644, 1475, 2611, 2683], 'either': [645], 'variant': [646, 1233], 'CJD-like': [647, 650], 'strains': [652, 1044, 1316, 2423], 'expressing': [656], 'protein.': [659, 1106, 1191, 1260, 3019], 'Embo': [660, 2001], 'Journal,': [661, 2002, 3157], '21,': [662], '6358–': [663], '6366.': [664], 'Atalay': [665], 'FO,': [666], 'Tolunay': [667], 'Ozgun': [669], 'G,': [670, 1071, 1526, 1791, 1807, 1814, 1879, 2304, 2651, 3281, 4002, 4186, 4323], 'Bekar': [671], 'A': [672, 1095, 1143, 1844, 2454, 3524], 'Zarifoglu': [674], '2015.': [676, 1538, 2376, 3194, 3674], 'disease:': [678, 2492, 4200], 'report': [679, 4203], 'four': [681], 'literature.': [687], 'Turk': [688], 'patoloji': [689], 'dergisi,': [690], '31,': [691], '148–': [692], '152.': [693], 'Baker': [694], 'HF,': [695], 'Ridley': [696], 'RM': [697], 'Wells': [699], 'GAH,': [700], '1993.': [701], 'Experimental': [702, 948, 2213], 'common': [710], 'marmoset.': [711], 'Veterinary': [712, 1052, 1107, 2436, 2936, 2957, 3305, 3311, 3468, 3995], 'Record,': [713, 2958], '132,': [714], '403–': [715], '406.': [716], 'Barria': [717, 750, 786, 812, 840, 1988], 'Balachandran': [719, 2193], 'Morita': [721], 'Kitamoto': [723, 4114], 'T,': [724, 1021, 1134, 2368, 2479, 3193, 4072, 4115], 'Barron': [725, 3930], 'R,': [726, 730, 917, 958, 980, 1019, 1122, 1537, 1957, 1985, 2593, 2676, 3113, 3322, 3503, 3505, 3562, 3858, 3931, 3958, 3974, 4014, 4016], 'Manson': [727, 1286, 1309, 3934], 'Knight': [729, 3504], 'Ironside': [731, 788, 1281, 1746, 2143, 3128, 3542, 3801, 3811, 3906, 3938], 'JW': [732, 789, 3939], 'Head': [734, 791, 1279, 3539, 3903, 3941], 'MW,': [735, 792, 1280, 3942], '2014a.': [736], 'Molecular': [737, 2149, 3022, 3944], 'barriers': [738], 'prions.': [743, 867, 1945, 2022, 2974], 'Emerging': [744, 1192, 3795, 3951], 'Infectious': [745, 1193, 1871, 3712, 3796, 3952], 'Diseases,': [746, 1194, 1685, 1872, 3713, 3797, 3953], '20,': [747, 909, 1584], '88–': [748], '97.': [749], 'Gonzalez-Romero': [752, 816, 1952], 'D': [753, 2529, 3836], 'Soto': [755, 821, 849, 1962, 1993, 2013, 2032, 2915, 3252], 'C,': [756, 822, 850, 1059, 1067, 1069, 1126, 1173, 1274, 1516, 1522, 1592, 1596, 1761, 1789, 1793, 1884, 1911, 1963, 1994, 2014, 2033, 2300, 2358, 2362, 2477, 2882, 3028, 3032, 3034, 3111, 3666, 3731, 3767, 3848, 3937, 4025, 4027, 4074, 4291, 4305], 'Cyclic': [758], 'amplification': [759, 1829, 3262], 'misfolding.': [763], 'In:': [764, 2721, 3819], 'Amyloid': [765], 'proteins:': [766], 'methods': [767], 'protocols,': [769], 'edition.': [771], 'Eds': [772, 3835], 'EM': [773], 'Sigurdsson,': [774], 'M': [775, 778, 1073, 1216, 1881, 2050, 2750, 3840, 4043, 4327], 'Calero': [776, 2516], 'Gasset,': [779], 'Humana': [780], 'Inc.,': [782], 'Totowa,': [783], '199–': [784], '212.': [785], '2014b.': [793], 'Exploring': [794], 'diseases': [801, 3886], 'vivo': [803], 'vitro': [806, 831, 861, 1436, 1479, 1973, 2017, 3913], 'approaches.': [807], '8,': [809], '85–': [810], '91.': [811], 'Mukherjee': [814], 'D,': [817, 974, 1751, 1953, 2308, 2599, 3172, 3326, 3929, 3976, 4234, 4238], 'Morales': [818, 1956, 1984], 'R': [819, 886, 1425, 1465, 1811, 3838], '2009.': [823, 2276, 3943], 'De': [824, 1463, 1803, 1958, 2091, 2507], 'novo': [825], 'generation': [826, 2018], 'infectious': [828, 1976, 2020], 'produces': [832], 'phenotype.': [836], 'PLoS': [837, 1555, 3269], 'Pathogens,': [838, 1556, 3270], '5.': [839], 'Telling': [842, 3255], 'GC,': [843, 3256], 'Gambetti': [844, 1990, 3002, 4264, 4329], 'P,': [845, 1029, 1204, 1268, 1377, 1384, 1418, 1627, 1631, 1923, 1955, 1987, 2009, 2105, 2202, 2236, 2322, 2324, 3003, 3121, 3123, 3385, 3389, 3612, 3668, 3771, 3850, 3860, 4265, 4299, 4311, 4330], 'Mastrianni': [846], 'JA': [847], '2011.': [851, 1077, 1815, 2815, 2922, 2967, 3009, 3048, 3480, 3908, 4116], 'Generation': [852], 'PrPSc': [859, 2430], 'interspecies': [863, 1155], 'cervid': [866], 'Chemistry,': [871], '286,': [872], '7490–': [873], '7495.': [874], 'Beck': [875, 912, 953, 1014, 2395, 3079, 3130, 3630], 'KE,': [876, 913, 954, 1015, 2396], 'Chaplin': [877, 3959], 'Stack': [879], 'Sallis': [881, 914, 955, 2397], 'RE,': [882, 915, 956, 2398], 'Simonini': [883, 3333], 'Lockey': [885, 916, 957, 1018, 3321], 'Spiropoulos': [888, 921, 988, 1033, 2412, 3319], '2010b.': [890], 'Lesion': [891], 'profiling': [892], 'at': [893, 3702], 'primary': [894, 936], 'isolation': [895], 'RIII': [897], 'insufficient': [900], 'distinguishing': [902], 'scrapie.': [906, 1051, 2634, 2689], 'Brain': [907, 1009], 'Pathology,': [908, 1010, 4132], '313–': [910], '322.': [911], 'Simmons': [918, 985, 1030, 2409, 3118, 3961], 'MM': [919, 986, 1031, 2410], '2010a.': [923], 'Ovine': [924], 'PrP': [925, 1228, 3365], 'genotype': [926], 'linked': [928], 'lesion': [930], 'profile': [931], 'immunohistochemistry': [933], 'patterns': [934, 2432], 'after': [935, 2383, 2859, 2996, 3147], 'wild-type': [942], 'mice.': [943, 3366, 3406], 'Neuropathology': [946], 'Neurology,': [949, 1300, 1368, 1660, 3238], '69,': [950], '483–': [951], '497.': [952], 'Vickery': [959, 1016, 2399], 'Beringue': [961, 1114, 1163, 1198, 1932, 2197, 3343], 'V,': [962, 1115, 1164, 1199, 1276, 2190, 2198, 2224, 2262, 2356, 2944, 3174, 3344], 'Laude': [963, 1140, 1177, 1218, 3348], 'H,': [964, 1061, 1141, 1178, 1219, 1723, 1907, 2515, 2597, 2698, 2741, 2743, 3396, 3417, 3419, 3458, 3978, 4004, 4037, 4110, 4244], 'Holder': [965, 1020], 'TM,': [966], 'Thorne': [967, 1022, 3335], 'L,': [968, 1023, 1091, 1130, 1166, 1208, 1270, 1506, 1508, 1755, 1805, 1877, 1929, 2088, 3115, 3164, 3336, 3375, 3966, 4313], 'Terry': [969, 1024], 'LA,': [970, 1025], 'Tout': [971, 3323], 'AC,': [972, 3324], 'Jayasena': [973, 3325], 'Griffiths': [975, 3317], 'PC,': [976, 3318], 'Cawthraw': [977], 'Ellis': [979], 'Balkema-Buschmann': [981, 2883, 3339], 'Groschup': [983, 1846, 2890, 2920, 3285, 3341], 'MH,': [984, 1847, 2891, 2921, 3286, 3342], '2012b.': [990], 'murine': [993, 1046], 'bioassay': [994, 2686], 'resolve': [996], 'Encephalopathy': [1000, 1646, 3685, 3791], 'showing': [1002], 'bovine': [1004, 1144, 1149, 1183, 1395, 1850, 3148, 3751], 'spongiform': [1005, 1150, 1396, 1851, 2719, 2899, 3089, 3149, 3293, 3752, 3815], 'encephalopathy': [1006, 1151, 1397, 2900, 3090, 3150], 'profile.': [1008], '22,': [1011, 2642, 3998], '265–': [1012], '279.': [1013], 'Denyer': [1026, 2401], 'Webb': [1028, 2403, 3120], '2012a.': [1035], 'interpretation': [1037, 2416], 'phenotypes': [1040, 2419], 'identify': [1042, 2421], 'following': [1045], 'bioassay:': [1047], 'characterisation': [1048, 2426], 'Research,': [1053, 1108, 2437, 2503, 2937, 3408], '43,': [1054, 1109, 2438], 'doi:10.1186/1297–9716-': [1055, 2439], '1143–': [1056, 2440], '1177.': [1057], 'Begue': [1058], 'Martinetto': [1060], 'Schultz': [1062], 'Rojas': [1064], 'E,': [1065, 1504, 1524, 2086, 2167, 2188, 2192, 2222, 2226, 2258, 2266, 2352, 2394, 2447, 2473, 2653, 2702, 3080, 3662, 3717, 3761], 'Romero': [1066], "D'Giano": [1068], 'Sevlever': [1070], 'Somoza': [1072], 'Taratuto': [1075], 'surveillance': [1080, 1569, 3435, 4053], 'Argentina,': [1082], '1997–2008.': [1083], 'Neuroepidemiology,': [1084, 2553], '37,': [1085, 3472, 4100], '193–': [1086], '202.': [1087], 'Benestad': [1088, 1914, 2369], 'SL,': [1089, 1915, 2099, 2370, 2657], 'Austbo': [1090], 'Olsaker': [1097], 'Healthy': [1100], 'goats': [1101], 'naturally': [1102, 1483], 'devoid': [1103], 'doi:': [1110, 2939], '10.1186/1297–9716-': [1111, 2940], '43–': [1112], '87.': [1113], 'O,': [1117, 1936, 2360, 3387], 'Le': [1118, 1169, 1200, 3345], 'Dur': [1119, 1170, 1201, 3346], 'Essalmani': [1121], 'Vilotte': [1123, 1174, 1213], 'JL,': [1124, 1214], 'Lacroux': [1125, 1910], 'Reine': [1127, 1167, 1205, 1926], 'F,': [1128, 1168, 1206, 1379, 1500, 1510, 1530, 1532, 1802, 1917, 1927, 2082, 2310, 2527, 2649, 3160, 3381, 3869, 4307], 'Herzog': [1129, 1165, 1928], 'Biacabe': [1131], 'AG,': [1132], 'Baron': [1133, 2367], 'Caramelli': [1135, 2319, 4326], 'Casalone': [1137, 1172, 2299, 2361, 4290], 'C': [1138, 2011, 3253], '2007.': [1142, 2767, 3544], 'acquires': [1146], 'epidemic': [1148], 'strain-like': [1152], 'phenotype': [1153], 'transmission.': [1156], 'Neuroscience,': [1159, 3023, 4282], '27,': [1160, 2003], '6965–': [1161], '6971.': [1162], 'JL': [1175], '2008a.': [1179, 1995], 'Transmission': [1180, 2169, 2277, 2377, 2984], 'atypical': [1182], '14,': [1195], '1898–': [1196], '1901.': [1197], 'Tixador': [1203], 'Lepourry': [1207], 'Perret-Liaudet': [1209], 'Haik': [1211, 1564], 'Fontes': [1215], '2008b.': [1220, 1964], 'Prominent': [1221], 'persistent': [1223], 'extraneural': [1224], 'infection': [1225, 1390], 'infected': [1231], 'CJD.': [1234, 2161], 'Plos': [1235, 2342, 2975, 3068, 3896], 'One,': [1236, 2343, 2976, 3069, 3897], '3.': [1237, 2344], 'Bessen': [1238], 'RA,': [1239], 'Kocisko': [1240, 4136], 'DA,': [1241, 3127, 3180, 4137], 'Raymond': [1242, 1419, 2047, 2559, 4140], 'GJ,': [1243, 1420, 2560, 4141], 'Nandan': [1244], 'Lansbury': [1246, 4144], 'PT': [1247, 4145], 'Caughey': [1249, 1421, 2045, 2052, 2561, 2603, 3579, 4147], 'B,': [1250, 1422, 1798, 2053, 2090, 2484, 2604, 3580, 3664, 3719, 3763, 4143, 4148, 4297, 4309], '1995.': [1251, 4149], 'Nongenetic': [1252], 'propagation': [1253, 1997], 'strain-specific': [1255], 'properties': [1256], 'Nature,': [1261, 1784, 2162, 3622], '375,': [1262], '698–': [1263], '700.': [1264], 'Bishop': [1265, 1304, 3861], 'MT,': [1266, 1305, 3862], 'Hart': [1267], 'Aitchison': [1269], 'Baybutt': [1271], 'HN,': [1272], 'Plinston': [1273], 'Thomson': [1275], 'Tuzi': [1277], 'NL,': [1278], 'JW,': [1282, 1747, 3129, 3543, 3802, 3812, 3907], 'RG': [1284, 1307], 'JC,': [1287, 1310, 1931, 3383], '2006.': [1288, 3643], 'Predicting': [1289], 'susceptibility': [1290, 1820], 'incubation': [1292, 2387, 3708], 'time': [1293], 'human-to-human': [1295], 'vCJD.': [1298], 'Lancet': [1299], '5,': [1301, 1948, 2219, 2255, 2391, 2759], '393–': [1302], '398.': [1303], '2010.': [1311, 2168, 2892, 3067, 3353, 3739, 3984], 'Defining': [1312], 'properties.': [1320], 'Proceedings': [1321, 1399, 1445, 1674, 2065, 2121, 2285, 2576, 4169], 'National': [1324, 1402, 1448, 2068, 2124, 2579, 4172], 'Academy': [1325, 1366, 1403, 1449, 2069, 2125, 2580, 4173], 'Sciences': [1327, 1405, 1451, 2071, 2127, 2582, 4175], 'United': [1330, 1408, 1454, 2074, 2130, 2585, 4178], 'States': [1331, 1409, 1455, 2075, 2131, 2586, 4179], 'America,': [1333, 1411, 1457, 2077, 2133, 2588, 4181], '107,': [1334], '12005–': [1335], '12010.': [1336], 'Biswas': [1337], 'Khandelwal': [1339], 'N,': [1340, 1373, 1375, 1512, 1925, 2084, 2302, 2318, 2354, 3125, 3176, 3453, 3479], 'Pandit': [1341], 'Roy': [1343], 'Guin': [1345], 'DS,': [1346, 2737], 'Gangopadhyay': [1347], 'G': [1348, 3005, 3283, 3735, 3781], 'Senapati': [1350], '2013.': [1352, 1566, 3139, 3459, 3785, 4084, 4198], 'Case': [1353], 'series': [1354, 1650], 'probable': [1356], 'Eastern': [1361], 'India.': [1362], 'Annals': [1363, 1658], 'Indian': [1365], '16,': [1369], '659–': [1370], '663.': [1371], 'Bons': [1372], 'Mestre-Frances': [1374], 'Belli': [1376], 'Cathala': [1378], 'Gajdusek': [1380, 1641, 2451, 2978, 3073, 3227], 'DC': [1381, 2979], 'Brown': [1383, 1626, 2201, 2235, 2271, 2323, 2371, 3185], '1999.': [1385], 'Natural': [1386], 'oral': [1389, 2753], 'nonhuman': [1392, 3754, 3793], 'primates': [1393], 'agents.': [1398], '96,': [1412], '4046–': [1413], '4051.': [1414], 'Bossers': [1415, 1461], 'Belt': [1417], 'de': [1423, 1901, 3496], 'Vries': [1424, 1464], 'Smits': [1427, 1467], '1997.': [1429, 1769, 2566, 3613], 'Scrapie': [1430, 3460], 'susceptibility-linked': [1431], 'polymorphisms': [1432, 1613, 2925], 'conversion': [1437, 1480, 2568, 3915, 4154], 'sheep': [1439, 1472, 1729, 1822, 2688, 2867, 3404, 3989], 'protease-resistant': [1443, 2057, 2574, 2615, 4159], 'forms.': [1444], '94,': [1458, 2589], '4931–': [1459], '4936.': [1460], '2000.': [1469], 'Susceptibility': [1470], 'assessed': [1476], 'nine': [1482], 'occurring': [1484], 'variants': [1485], 'PrP.': [1487], 'Virology,': [1490, 1738, 1839, 2693, 2909, 3370], '74,': [1491], '1407–': [1492], '1414.': [1493], 'Bouybayoune': [1494], 'Mantovani': [1496], 'Del': [1498], 'Gallo': [1499], 'Bertani': [1501], 'Restelli': [1503], 'Comerio': [1505], 'Tapella': [1507], 'Baracchi': [1509], 'Fernandez-Borges': [1511, 2083], 'Mangieri': [1513], 'Bisighini': [1515], 'Beznoussenko': [1517], 'GV,': [1518], 'Paladini': [1519], 'Balducci': [1521], 'Micotti': [1523], 'Forloni': [1525], 'Castilla': [1527, 1950, 1982, 2006, 2027, 2111, 3244], 'Fiordaliso': [1529], 'Tagliavini': [1531], 'Imeri': [1533], 'L': [1534, 1562], 'Chiesa': [1536], 'Transgenic': [1539], 'fatal': [1540], 'familial': [1541], 'insomnia': [1542], 'indicate': [1544, 1773], 'infectivity-independent': [1546], 'mechanisms': [1547], 'pathogenesis': [1549, 2716], 'phenotypic': [1551], 'expression': [1552], 'disease.': [1554, 1573, 1620, 1657, 2552, 3209, 3806], '11,': [1557, 2042], 'doi:10.1371/journal.ppat.1004796.': [1558], 'Brandel': [1559, 4032], 'JP,': [1560, 2207, 2241, 2275, 2329, 2375, 4033], 'Peckeu': [1561], 'French': [1568], 'network': [1570], 'Epidemiological': [1574], 'France': [1577], 'worldwide.': [1579], 'Transfusion': [1580], 'Clinique': [1581], 'Biologique,': [1583], '395–': [1585], '397.': [1586], 'Bratosiewicz-Wasik': [1587], 'Smolen-Dzirba': [1589], 'Watala': [1591], 'Rozemuller': [1593, 3881], 'AJ,': [1594], 'Jansen': [1595, 1599, 3847, 3875, 4040], 'Spliet': [1597, 3873], 'W,': [1598, 3038, 3721, 3765, 3872], 'GH,': [1600, 3876, 4041], 'Wasik': [1601], 'TJ': [1602], 'Liberski': [1604], 'PP,': [1605], 'Association': [1607], 'PRNP': [1610, 3654], 'regulatory': [1611], 'region': [1612], 'occurrence': [1616], 'Folia': [1621], 'Neuropathologica,': [1622, 3922], '50,': [1623, 3757], '68–': [1624], '73.': [1625], 'Gibbs': [1628, 2981, 3071, 3224], 'CJ,': [1629, 1768], 'Rodgersjohnson': [1630], 'Asher': [1632, 2448, 3075, 3218], 'DM,': [1633, 3076, 3219], 'Sulima': [1634], 'MP,': [1635, 2665, 3078], 'Bacote': [1636], 'Goldfarb': [1638], 'LG': [1639], 'DC,': [1642, 2452, 3074, 3228], '1994.': [1643], 'Human': [1644, 3884], '-': [1647, 2460, 3523, 4161], 'national-institutes-of-health': [1649], '300': [1652], 'experimentally': [1655], 'transmitted': [1656, 2334], '35,': [1661], '513–': [1662], '529.': [1663], 'Bruce': [1664, 1697, 1709, 1742, 2668], 'Strain': [1667, 1725, 3288], 'typing': [1668, 3289], 'TSEs.': [1673, 2181], 'International': [1677, 2639], 'Conference': [1678], 'Prion': [1684, 2288], '15th': [1686], '18th': [1688], 'September': [1689, 2294], '2002,': [1690], 'Edinburgh,': [1691], 'Scotland,': [1692], 'UK.': [1693], 'Available': [1694], 'at:': [1695], 'http://www.blackwellpublishing.com/products/journals/suppmat/nan/nan477/NAN477sm.pdf.': [1696], 'ME,': [1698, 1710, 1743], '2003.': [1699, 2630], 'strain': [1701, 2153, 2250, 2282, 3617], 'variation.': [1702], 'British': [1703, 2497], 'Bulletin,': [1705], '66,': [1706], '99–': [1707], '108.': [1708], 'Boyle': [1711], 'Cousens': [1713, 1762, 3508], 'McConnell': [1715, 1748], 'Foster': [1717], 'Goldmann': [1719], 'W': [1720, 3670, 3843], 'Fraser': [1722, 1764], 'natural': [1728], 'comparison': [1732, 1831], 'BSE.': [1734, 3621], 'General': [1737, 2692, 2908, 3369], '83,': [1739], '695–': [1740], '704.': [1741], 'RG,': [1745, 2532, 3507, 4031], 'Drummond': [1750], 'Suttie': [1752], 'McCardle': [1754], 'Chree': [1756], 'Hope': [1758, 3351], 'Birkett': [1760], 'H': [1765, 3349], 'Bostock': [1767], 'Transmissions': [1770], "'new": [1775, 2159], "variant'": [1776, 2160], 'CJD': [1777], 'caused': [1779], 'agent.': [1783], '389,': [1785, 3623], '498–': [1786], '501.': [1787], 'Bucalossi': [1788], 'Cosseddu': [1790], "D'Agostino": [1792], 'Di': [1794, 2645], 'Bari': [1795, 2646], 'Chiappini': [1797], 'Conte': [1799, 2654], 'Rosone': [1801], 'Grossi': [1804], 'Scavia': [1806], 'Agrimi': [1808, 2672], 'U,': [1809, 3279, 3727, 3769], 'Nonno': [1810, 2675], 'Vaccari': [1813, 2650], 'Assessment': [1816], 'genetic': [1819, 3892], 'misfolding': [1827], 'cyclic': [1828], 'studies.': [1836], '85,': [1840], '8386–': [1841], '8392.': [1842], 'Buschmann': [1843, 3274], '2005.': [1848, 2950, 3287, 4266], 'Highly': [1849], 'encephalopathy-sensitive': [1852], 'confirm': [1855], 'essential': [1857], 'restriction': [1858], 'nervous': [1863, 3694], 'system': [1864, 3695], 'clinically': [1866], 'diseased': [1867], 'cattle.': [1868], '192,': [1873], '934–': [1874], '942.': [1875], 'Cartier': [1876], 'Quiroz': [1878], 'Leiva': [1880], 'Vergara': [1883], 'Clinical': [1886], 'pathologic': [1888], 'identification': [1889], 'different': [1891], 'forms': [1892, 4160], 'Creutzfeldt': [1894], 'Jakob': [1895], 'Chile.': [1898], 'Revista': [1899], 'Medica': [1900], 'Chile,': [1902], '140,': [1903], '161–': [1904], '168.': [1905], 'Torres': [1908, 2199, 2233, 3772], 'Douet': [1912], 'JY,': [1913], 'Lantier': [1916, 1920], 'Lugan': [1918], 'Costes': [1922], 'Aron': [1924], 'Espinosa': [1930], 'V': [1933], 'Nature': [1946, 2040, 2998], 'Communications,': [1947], '5821.': [1949], 'Saa': [1954, 1986, 2008, 2029], 'Castro': [1959, 2092], 'J': [1960, 2144, 3044], 'Crossing': [1965], 'species': [1967, 3267, 4167], 'barrier': [1968], 'PrP(Sc)': [1970], 'replication': [1971], 'generates': [1974], 'unique': [1975], 'Prions.': [1977], 'Cell,': [1978, 2023], '134,': [1979], '757–': [1980], '768.': [1981], 'P': [1991, 2030, 2272, 2372], 'Cell-free': [1996], 'strains.': [2000], '2557–': [2004], '2566.': [2005], 'Hetz': [2010], '2005b.': [2015], 'In': [2016], '121,': [2024, 3923], '195–': [2025], '206.': [2026], '2005a.': [2034], 'Detection': [2035], 'blood.': [2039], 'Medicine,': [2041], '982–': [2043], '985.': [2044], 'WS,': [2046], 'LD,': [2048], 'Horiuchi': [2049], '1998.': [2054, 2605, 3581, 3803], 'Inhibition': [2055], 'formation': [2060], 'porphyrins': [2062], 'phthalocyanines.': [2064], '95,': [2078], '12117–': [2079], '12122.': [2080], 'Chianini': [2081, 2648], 'Vidal': [2085], 'Gibbard': [2087], 'Pintadoe': [2089], 'Priola': [2094, 4138], 'SA,': [2095, 4139], 'Hamilton': [2096, 2658], 'Eaton': [2098, 2656], 'Finlayson': [2100, 2660], 'Pang': [2102], 'Y,': [2103, 3107, 4108], 'Steele': [2104, 2662], 'Reid': [2106, 2666], 'HW,': [2107, 2667], 'Dagleish': [2108, 2664], 'MP': [2109], 'Rabbits': [2114], 'resistant': [2117, 3649], 'infection.': [2120], '109,': [2134], '5080–': [2135], '5085.': [2136], 'Sidle': [2139, 3602], 'KCL,': [2140, 3603], 'Meads': [2141], '1996.': [2148, 2708], 'analysis': [2150, 3430], 'variation': [2154], 'aetiology': [2157], '383,': [2163], '685–': [2164], '690.': [2165], 'Comoy': [2166, 2187, 2221, 2257, 2297, 2345], 'primates.': [2172, 2217, 3755, 3794], 'Workshop': [2173], 'epidemiology': [2176, 2632, 2714], '30': [2182], 'April': [2183], '2010,': [2184], 'Torino,': [2185], 'Italy.': [2186], 'Durand': [2189, 2223, 2261, 2355], 'Correia': [2191, 2225, 2265, 2351], 'Richt': [2195, 2229, 2259, 2363], 'Hills': [2203, 2237], 'B': [2204, 2238, 2562, 2601, 4341], 'Deslys': [2206, 2240, 2274, 2328, 2374], '2011b.': [2208], 'CWD:': [2212], 'transmissions': [2214], 'non-human': [2216], '101.': [2220], 'Freire': [2227, 2263, 2305], 'Greenlee': [2231, 2365], '2011a.': [2242], 'Transmissibility': [2243, 4272], 'BSE-L': [2245], 'cattle-adapted': [2247], 'TME': [2248, 2280], 'cynomolgus': [2252], 'macaque.': [2253, 2284], '100.': [2256], 'Hamir': [2267], 'Ruchoux': [2269, 2311], 'MM,': [2270, 2312, 3867, 3962], 'bovine-passaged': [2279], '2009': [2289], 'Conference.': [2290], 'Thessaloniki,': [2291], 'Greece,': [2292], '23–25': [2293], '2009,': [2295], '46.': [2296], 'EE,': [2298, 2346], 'Lescoutra-Etchegaray': [2301, 2353], 'Zanusso': [2303, 4322], 'Marce': [2307], 'Auvre': [2309], 'Ferrari': [2313], 'Monaco': [2315, 4320], 'Sales': [2317], 'Leboulch': [2321], 'Lasmezas': [2325], 'CI': [2326], '2008.': [2330, 2677, 3257, 3443, 4331], '(BASE)': [2333], 'asymptomatic': [2336], 'aging': [2337], 'cattle': [2338], 'primate.': [2341], 'Mikol': [2347], 'Luccantoni-Freire': [2349], 'Dehen': [2357], 'JA,': [2364, 3188, 3631], 'JJ,': [2366, 4315], 'primate': [2382], 'extended': [2385], 'silent': [2386], 'period.': [2388, 3709], 'Reports,': [2390], 'doi:10.1038/srep11573.': [2392], 'Corda': [2393], 'PR,': [2404], 'Bellworthy': [2405], 'SJ,': [2406, 4046, 4083], 'Spencer': [2407, 3106], 'YI,': [2408], 'mice:': [2425], 'using': [2429], 'distribution': [2431], 'brain.': [2435], '1186.': [2441], 'Davanipour': [2442, 2470], 'Z,': [2443, 2471], 'Alter': [2444], 'Sobel': [2446, 2472], 'DM': [2449], '1985.': [2453], 'case-control': [2455, 2495, 2538, 3525], 'dietary': [2461], 'risk-factors.': [2462, 3529], 'American': [2463, 4129], 'Epidemiology,': [2466], '122,': [2467], '443–': [2468], '451.': [2469], 'Ziogas': [2474], 'Smoak': [2476], 'Bohr': [2478], 'Doram': [2480], 'K': [2481, 2888, 3423, 4194], 'Liwnicz': [2483], 'Dietary': [2486], 'confirmatory': [2494], 'study.': [2496], 'Medicine': [2500, 3306, 4210, 4220], '4,': [2504], '2388–': [2505], '2417.': [2506], 'Pedro': [2508], 'Cuesta': [2509], 'Ruiz': [2511], 'Tovar': [2512], 'Ward': [2514], 'Smith': [2518, 3510], 'Verduras': [2520], 'CA,': [2521, 3854, 4078], 'Pocchiari': [2522], 'Turner': [2524], 'ML,': [2525, 4236, 4317], 'Forland': [2526], 'Palm': [2528], 'Sensitivity': [2534], 'biases': [2536], 'medical': [2541], 'procedures,': [2542], 'particularly': [2543], 'surgery': [2544], 'blood': [2546, 3748], 'transfusion,': [2547], '39,': [2554], '1–': [2555, 2805], '18.': [2556, 3834], 'DebBurman': [2557], 'SK,': [2558], 'Lindquist': [2564], 'Chaperone-supervised': [2567], 'form.': [2575], '13938–': [2590], '13943.': [2591], 'Demaimay': [2592], 'Harper': [2594], 'Gordon': [2596], 'Weaver': [2598], 'Chesebro': [2600, 4142], 'Structural': [2606], 'aspects': [2607, 2785], 'Congo': [2609], 'red': [2610], 'inhibitor': [2613], 'formation.': [2618], 'Neurochemistry,': [2621], '71,': [2622, 3499], '2534–': [2623], '2541.': [2624], 'Detwiler': [2625], 'LA': [2626], 'Baylis': [2628], 'Revue': [2635], 'Scientifique': [2636], 'tt': [2637], 'Technique-Office': [2638], 'des': [2640], 'Epizooties,': [2641], '121–': [2643], '143.': [2644, 3925], 'Esposito': [2652], 'PJ,': [2663], 'U': [2673], 'bank': [2679], 'vole': [2680], '(Myodes': [2681], 'glareolus)': [2682], 'sensitive': [2685], '89,': [2694], '2975–': [2695], '2985.': [2696], 'Diringer': [2697], 'Beekes': [2699, 3778], 'Baldauf': [2701], 'Cassens': [2703], 'S': [2704, 2946, 3135], 'Ozel': [2706], 'Amyloidosis:': [2709], 'key': [2711], 'transmissible': [2718, 3292], 'encephalopathies.': [2720], 'Bovine': [2722, 3683, 3789], 'Encephalopathy-The': [2724], 'Dilemma.': [2726], 'Ed': [2727, 3568], 'CJ': [2728, 3225, 3980], 'Gibbs,': [2729], 'Springer,': [2730], 'New': [2731, 3991], 'York,': [2732], 'US,': [2733], '251–': [2734], '270.': [2735], 'Donaldson': [2736], 'Kobayashi': [2738, 4103], 'Ohno': [2740], 'Yagita': [2742], 'Williams': [2744], 'IR': [2745], 'Mabbott': [2747], 'NA,': [2748], 'cell-depletion': [2751], 'blocks': [2752], 'pathogenesis.': [2756], 'Mucosal': [2757, 3195], 'Immunology,': [2758], '216–': [2760], '225.': [2761], '(European': [2763], 'Food': [2764], 'Safety': [2765], 'Authority),': [2766], 'hazards': [2775], 'certain': [2784], 'related': [2786], '(TSEs)': [2794], 'caprine': [2798, 2929], 'animals.': [2799], '2007,': [2803], '466,': [2804], '10.': [2806], 'BIOHAZ': [2808, 2842], '(EFSA': [2810, 2844], 'Hazards),': [2814, 2848], 'humans.': [2831, 3950], '2011;': [2834], '(1):': [2836], '1945,': [2837], '111': [2838], 'pp.': [2839, 2877], 'doi:10.2903/j.efsa.2011.1945.': [2840], 'situation': [2855], 'EU': [2858], '10': [2860], 'years': [2861, 2995, 3433], 'monitoring': [2863], 'control': [2865], 'goats.': [2869], '2014;': [2872], '12': [2873, 3432], '(7):': [2874], '3781,': [2875], '155': [2876], 'doi:10.2903/j.efsa.2014.3781.': [2878], 'Eiden': [2879, 2913, 3276], 'Muller': [2885], 'Baumgartner': [2887], 'Biochemical': [2893], 'immunohistochemical': [2895], 'feline': [2898], 'German': [2903, 3291], 'captive': [2904], 'cheetah.': [2905], '91,': [2910, 3371], '2874–': [2911], '2883.': [2912], 'EO,': [2916], 'Mettenleiter': [2917], 'TC': [2918], 'Effects': [2923], 'alleles': [2932], 'cell-free': [2934, 3914, 4153], 'conversion.': [2935, 3591], '42,': [2938], '1142–': [2941], '1130.': [2942], 'Epstein': [2943], 'Pointing': [2945], 'Halfacre': [2948], 'Falkland': [2955], 'islands.': [2956], '157,': [2959], '667–': [2960], '668.': [2961], 'Fryer': [2962], 'HR': [2963], 'McLean': [2965, 4077], 'AR,': [2966], 'There': [2968], 'safe': [2971], 'dose': [2972], '6.': [2977, 3070], 'CJJ,': [2982, 3072], '1972.': [2983], 'kuru': [2986], 'man': [2988], 'Rhesus': [2990], 'monkey': [2991], '(Macaca': [2992], 'Mulatta)': [2993], '8.5': [2994], 'inoculation.': [2997], '(London),': [2999], '240,': [3000], '351.': [3001], 'Puoti': [3004], 'Zou': [3007, 4231, 4324], 'WQ,': [3008, 4232, 4325], 'Variably': [3010], 'protease-sensitive': [3011], 'prionopathy:': [3012], 'novel': [3014], '45,': [3024], '422–': [3025], '424.': [3026], 'Gao': [3027], 'Shi': [3029], 'Q,': [3030], 'Tian': [3031], 'Chen': [3033, 4247, 4261, 4300], 'Han': [3035], 'Zhou': [3037], 'Zhang': [3039, 3043], 'BY,': [3040], 'Jiang': [3041], 'HY,': [3042, 4246], 'Dong': [3046], 'XP,': [3047], 'epidemiological,': [3050], 'clinical,': [3051], 'features': [3054], 'patients': [3059], 'China:': [3061], 'Surveillance': [3062, 4085], '2006': [3065], 'Alpers': [3077], 'Daniel': [3081], 'PM': [3082], 'Matthews': [3084, 3513], 'WB,': [3085, 3514], '1968.': [3086], 'chimpanzee': [3094], 'virus': [3096], 'kuru.': [3097], 'Science': [3098], '(Washington': [3099], 'DC),': [3100], '161,': [3101], '388–': [3102], '389.': [3103], 'Gill': [3104], 'ON,': [3105], 'Richard-Loendt': [3108], 'Kelly': [3110], 'Dabaghian': [3112], 'Boyes': [3114], 'Bellerby': [3122], 'Andrews': [3124], 'Hilton': [3126], 'Poulter': [3132, 3636], 'Mead': [3134], 'Brandner': [3137], 'Prevalent': [3140], 'abnormal': [3141], 'appendixes': [3146], 'epizootic:': [3151], 'large': [3152], 'scale': [3153], 'survey.': [3154], 'BMJ-British': [3155], '347.': [3158], 'Goni': [3159], 'Mathiason': [3161], 'CK,': [3162], 'Yim': [3163], 'Wong': [3165], 'KL,': [3166], 'Hayes-Klug': [3167], 'Nalls': [3169], 'Peyser': [3171], 'Estevez': [3173], 'Denkers': [3175], 'Xu': [3177], 'JF,': [3178], 'Osborn': [3179], 'Miller': [3181], 'KV,': [3182], 'Warren': [3183], 'RJ,': [3184], 'DR,': [3186], 'Chabalgoity': [3187], 'Hoover': [3189], 'EA': [3190], 'Wisniewski': [3192], 'immunization': [3196], 'attenuated': [3199], 'Salmonella': [3200], 'vaccine': [3201], 'partially': [3202], 'protects': [3203], 'white-tailed': [3204], 'deer': [3205], 'chronic': [3207], 'wasting': [3208, 4268], 'Vaccine,': [3210], '33,': [3211], '726–': [3212], '733.': [3213], 'Goudsmit': [3214], 'Morrow': [3216], 'CH,': [3217, 3557], 'Yanagihara': [3220], 'RT,': [3221], 'Masters': [3222, 4011, 4079], 'CL,': [3223, 4012], '1980.': [3229], 'against': [3233], 'Alzheimer-disease.': [3237], '30,': [3239], '945–': [3240], '950.': [3241], 'Green': [3242, 3331], 'KM,': [3243, 3723], 'Seward': [3246], 'TS,': [3247], 'Napier': [3248], 'DL,': [3249], 'Jewell': [3250], 'JE,': [3251], 'Accelerated': [3258], 'high': [3259], 'fidelity': [3260], 'within': [3263], 'barriers.': [3268], '4.': [3271], 'Gretzschel': [3272], 'Ziegler': [3278], 'Luhken': [3280], 'Erhardt': [3282], 'encephalopathies': [3294, 3816], 'biochemical': [3301], 'methods.': [3302], 'Series': [3307], 'B-Infectious': [3308], 'Diseases': [3309, 4096], 'Public': [3312, 4212, 4222], 'Health,': [3313, 4223], '52,': [3314], '55–': [3315], '63.': [3316], 'Plater': [3327], 'Chave': [3329], 'RB,': [3332, 4258], 'Dexter': [3337], 'Characterization': [3354], 'Great': [3360], 'Britain': [3361], '2132–': [3372], '2138.': [3373], 'Gruner': [3374], 'Elsen': [3376], 'Khang': [3378], 'JVT,': [3379], 'Eychenne': [3380], 'Caritez': [3382], 'Jacquiet': [3384], 'Sarradin': [3388], 'Cortet': [3390], 'Richer': [3392], 'N': [3393], 'Leroux': [3395], '2004.': [3397], 'Nematode': [3398], 'parasites': [3399], 'experiments': [3402], 'Parasitology': [3407], '93,': [3409], '493–': [3410], '498.': [3411], 'Gubbels': [3412], 'Bacci': [3414], 'Laursen': [3416], 'Hogenhaven': [3418], 'Cowan': [3420], 'Molbak': [3422], 'Christiansen': [3425], 'Description': [3428], 'Denmark,': [3440], '1997': [3441], 'Eurosurveillance,': [3444], '17,': [3445], '23–': [3446], '31.': [3447], 'Gurel': [3448], 'Gulcubuk': [3450], 'Turan': [3452], 'Helps': [3454], 'CR': [3455], 'Yilmaz': [3457], 'Northern': [3463], 'Cyprus.': [3464], 'Turkish': [3465], '&': [3469, 4211, 4221], 'Animal': [3470], 'Sciences,': [3471], '311–': [3473], '315.': [3474], 'Hajjaj': [3475], 'I': [3476], 'Kissani': [3478], 'case': [3482, 4202], 'presumed': [3484], 'Marrakech,': [3489], 'Morocco.': [3490], 'Médecine': [3491], 'tropicale:': [3492], 'revue': [3493], 'du': [3494], 'Corps': [3495], 'santé': [3497], 'colonial,': [3498], '289–': [3500], '291.': [3501], 'Harries-Jones': [3502], 'PG': [3511], '1988.': [3515], 'England': [3519], 'Wales,': [3521], '1980–1984': [3522], 'Neurology': [3532, 4060], 'Neurosurgery': [3533, 4061], 'Psychiatry,': [3535, 4063], '51,': [3536], '1113–': [3537], '1119.': [3538], 'MW': [3540, 3904], 'vCJD': [3545, 3619], 'gut:': [3548], 'implications': [3549], 'endoscopy.': [3551], 'Gut,': [3552], '56,': [3553], '9–': [3554], '11.': [3555], 'Hennekens': [3556], 'Buring': [3558], 'JE': [3559], 'Doll': [3561], '1987.': [3563], 'Epidemiology': [3564], 'medicine.': [3566], '255,': [3567], 'SL': [3569], 'Mayrent,': [3570], 'Boston:': [3571], 'Little,': [3572], 'Brown.': [3573], '246–': [3574], '252.': [3575], 'Herrmann': [3576], 'LM': [3577], 'importance': [3583], 'disulfide': [3586], 'bond': [3587], 'Neuroreport,': [3592], '9,': [3593], '2457–': [3594], '2461.': [3595], 'Doey': [3608], 'LJ': [3609], 'Lantos': [3611], 'same': [3615], 'causes': [3618], '448–': [3624], '450.': [3625], 'Campbell': [3632], 'TA,': [3633], 'Dickinson': [3634], 'Distinct': [3644], 'glycoform': [3645], 'ratios': [3646], 'protease': [3648], 'associated': [3652], 'point': [3655], 'mutations.': [3656], 'Brain,': [3657], '129,': [3658], '676–': [3659], '685.': [3660], 'Holznagel': [3661, 3716, 3760], 'Yutzy': [3663, 3718, 3762], 'Kruip': [3665, 3766], 'Bierke': [3667, 3770], 'Schulz-Schaeffer': [3669, 3720, 3764], 'Löwer': [3672], 'Foodborne-transmitted': [3675], 'brain': [3679], 'cows': [3681], 'ascend': [3686], 'afferent': [3688], 'neurons': [3689], 'simian': [3692], 'central': [3693], 'spread': [3697], 'tonsils': [3699], 'spleen': [3701], 'late': [3704], 'stage': [3705], 'pii:': [3714], 'jiv232.': [3715], 'Hanschman': [3722], 'Stuke': [3724], 'Hahmann': [3726, 3768], 'Torner': [3728], 'Coulibaly': [3730], 'Hunsmann': [3734, 3780], 'Lower': [3737], 'Increase': [3740], 'CD230': [3742], '(cellular': [3743], 'protein)': [3745], 'fluorescence': [3746], 'lymphocytes': [3749], 'encephalopathy-infected': [3753], 'Transfusion,': [3756], '452–': [3758], '466.': [3759], 'Kim': [3774], 'YS,': [3775], 'Thomzig': [3776], 'Loewer': [3783], 'Foodborne': [3786], '19,': [3798], '712–': [3799], '720.': [3800], 'New-variant': [3804], 'Neuropathology,': [3807], '18,': [3808], '131–': [3809], '138.': [3810], '(prion': [3817], 'diseases).': [3818], 'microbiology:': [3821], 'guide': [3823], 'microbial': [3825], 'infections:': [3826], 'pathogenesis,': [3827], 'immunity,': [3828], 'investigation': [3830], 'control.': [3832], 'Ed.': [3833], 'Greenwood,': [3837], 'Slack,': [3839], 'Barer': [3841], 'Irving,': [3844], '607–': [3845], '613.': [3846], 'Parchi': [3849], 'Capellari': [3851], 'Ibrahim-Verbaas': [3853, 4026], 'Schuur': [3855], 'Strammiello': [3857], 'Corrado': [3859], 'Van': [3863, 3870, 3877, 4023], 'Gool': [3864], 'WA,': [3865], 'Verbeek': [3866], 'Baas': [3868], 'Saane': [3871], 'WGM,': [3874], 'Duijn': [3878, 4024], 'CM': [3879], 'AJM,': [3882], 'Netherlands': [3889], '(1998–2009):': [3890], 'Clinical,': [3891], 'aspects.': [3895], '7.': [3898], 'Jones': [3899, 3926], 'Peden': [3901], 'AH,': [3902], 'application': [3910], 'systems': [3916], 'diseases.': [3920], 'Acta': [3921], '135–': [3924], 'Wight': [3928], 'Prowse': [3936], 'model': [3945, 4163], '15,': [3954], '2013–': [3955], '2016.': [3956], 'Kittelberger': [3957], 'MJ,': [3960, 3970, 4242, 4289], 'Ramirez-Villaescusa': [3963], 'McIntyre': [3965], 'MacDiarmid': [3967], 'SC,': [3968], 'Hannah': [3969], 'Jenner': [3971], 'Bueno': [3973], 'Bayliss': [3975], 'Black': [3977], 'Pigott': [3979], "O'Keefe": [3982], 'JS,': [3983], 'scrapie/Nor98': [3986], 'Zealand.': [3992], 'Diagnostic': [3996], 'Investigation,': [3997], '863–': [3999], '875.': [4000], 'Klug': [4001, 4067], 'Wand': [4003], 'Simpson': [4005, 4075], 'Boyd': [4007, 4069], 'Law': [4009], 'Matej': [4013], 'Howley': [4015], 'Farrell': [4017], 'Breithaupt': [4019], 'Zerr': [4021], 'Mackenzie': [4028], 'Alperovitch': [4034], 'Budka': [4036], 'Kovacs': [4038], 'GG,': [4039], 'Coulthard': [4042], 'Collins': [4045, 4082], '2013a.': [4047], 'Intensity': [4048], 'predicts': [4054], 'observed': [4055], 'incidence.': [4057], '84,': [4064], '1372–': [4065], '1377.': [4066], 'GM,': [4068], 'Zhao': [4071], 'Stehmann': [4073], 'CL': [4080], 'Australia:': [4090], 'update': [4091], 'December': [4093], 'Communicable': [4095], 'Intelligence': [4097], 'Quarterly': [4098], 'Report,': [4099], 'E115–': [4101], '120.': [4102], 'Mizukoshi': [4105], 'K,': [4106, 4248, 4252], 'Iwasaki': [4107], 'Miyata': [4109], 'Yoshida': [4111], 'Y': [4112], 'Co-occurrence': [4117], 'Types': [4119], '1': [4120], '2': [4122], 'PrPres': [4123], 'MM1.': [4128], '178,': [4133], '1309–': [4134], '1315.': [4135], 'Species-specificity': [4150], 'barrier.': [4168], '92,': [4182], '3923–': [4183], '3927.': [4184], 'Kojima': [4185], 'Tatsuno': [4187], 'BK,': [4188], 'Inaba': [4189], 'Velligas': [4191], 'Masaki': [4193], 'Liow': [4196], 'KK,': [4197], 'differential': [4205], 'diagnoses.': [4206], "Hawai'i": [4207], 'Health': [4213], ':': [4214], 'Asia': [4218], 'Pacific': [4219], '72,': [4224], '136–': [4225], '139.': [4226], 'Kong': [4227, 4286], 'QZ,': [4228, 4287], 'Huang': [4229, 4294], 'SH,': [4230, 4295], 'Vanegas': [4233], 'Wang': [4235, 4298, 4312, 4316], 'Wu': [4237], 'Yuan': [4239], 'Zheng': [4241, 4288], 'Bai': [4243], 'Deng': [4245], 'Jenny': [4249], "O'Rourke": [4251], 'Belay': [4253], 'ED,': [4254], 'Schonberger': [4255], 'LB,': [4256], 'Petersen': [4257], 'Sy': [4259], 'MS,': [4260], 'SG': [4262], 'Chronic': [4267], 'elk:': [4271], 'humans': [4274], 'examined': [4275], 'mouse': [4278], 'models.': [4279], '25,': [4283], '7944–': [4284], '7949.': [4285], 'Qing': [4292], 'LT,': [4293], 'Chakraborty': [4296], 'FS,': [4301], 'Cali': [4302], 'Corona': [4304], 'Martucci': [4306], 'Iulini': [4308], 'Acutis': [4310], 'Liang': [4314], 'Li': [4318], 'XY,': [4319], 'Evaluation': [4332]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4211151853', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}], 'updated_date': '2024-12-07T20:40:56.848957', 'created_date': '2022-02-13'}
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