Publication Information

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'https://doi.org/10.2903/j.efsa.2011.2405Citations:': [79], '25': [80], 'members:': [82], 'Jan': [83], 'Alexander,': [84], 'Diane': [85, 146], 'Benford,': [86, 147], 'Alan': [87], 'Boobis,': [88], 'Sandra': [89], 'Ceccatelli,': [90], 'Bruce': [91], 'Cottrill,': [92], 'Jean-Pierre': [93], 'Cravedi,': [94], 'Alessandro': [95], 'Di': [96], 'Domenico,': [97], 'Daniel': [98, 150], 'Doerge,': [99, 151], 'Eugenia': [100], 'Dogliotti,': [101], 'Lutz': [102], 'Edler,': [103], 'Peter': [104, 110, 154], 'Farmer,': [105], 'Metka': [106], 'Filipič,': [107], 'Johanna': [108], 'Fink-Gremmels,': [109], 'Fürst,': [111], 'Thierry': [112], 'Guérin,': [113], 'Helle': [114], 'Katrine': [115], 'Knutsen,': [116], 'Miroslav': [117], 'Machala,': [118], 'Antonio': [119], 'Mutti,': [120], 'Martin': [121], 'Rose,': [122], 'Josef': [123], 'Schlatter': [124], 'and': [125, 156, 169, 175, 187, 206, 217, 265, 269, 281, 288, 307, 342, 345, 360, 441, 450, 465, 469, 584, 610, 639, 646, 655, 669, 683, 695, 710, 774, 791, 805, 838, 844, 854, 872, 880, 904, 914, 918, 931, 940, 952, 966, 977, 985, 997, 1012, 1020, 1036, 1059, 1070, 1088, 1107, 1128, 1144, 1151, 1166, 1171, 1178, 1194, 1225, 1247, 1269, 1303, 1363, 1376, 1393, 1422, 1449, 1465, 1473, 1494, 1499, 1510, 1518, 1541, 1574, 1605, 1624, 1634, 1640, 1649, 1673, 1680, 1687, 1697, 1704, 1719, 1741, 1751, 1762, 1767, 1780, 1820, 1825, 1844, 1852, 1862, 1880, 1889, 1897, 1903, 1910, 1918, 1923, 1937, 1944, 1970, 1982, 1996, 2003, 2008, 2012, 2034, 2041, 2058, 2075, 2090, 2100, 2105, 2109, 2124, 2135, 2153, 2167, 2211, 2248, 2260, 2266, 2276, 2320, 2342, 2351, 2371, 2377, 2391, 2407, 2437, 2448, 2467, 2504, 2531, 2556, 2572, 2587, 2614, 2619, 2623, 2648, 2659, 2666, 2698, 2731, 2746, 2755, 2760, 2863, 2878, 2906, 2912, 2927, 2949, 2970, 2987, 3000, 3025, 3043, 3048, 3053, 3058, 3068, 3081, 3104, 3116, 3133, 3138, 3161, 3171, 3188, 3210, 3223, 3264, 3277, 3291, 3313, 3318, 3326, 3370, 3375, 3395, 3439, 3457, 3475, 3484, 3499, 3513, 3522, 3529, 3533, 3549, 3555, 3572, 3585, 3589, 3678, 3696, 3728, 3754, 3767, 3777, 3785, 3803, 3832, 3884, 3913, 3918, 3931, 3937, 3944, 3952, 3970, 3977, 3987, 3993, 4005, 4016, 4023], 'Rolaf': [126], 'van': [127, 158], 'Leeuwen': [128], 'Correspondence:': [129], '[email protected]': [130], 'Acknowledgement:': [131], 'The': [132, 198, 350, 387, 499, 679, 699, 706, 1118, 1769, 1906, 1956, 2044, 2062, 2094, 2141, 2157, 2422, 2535, 2799, 3268, 3464, 3781, 3861, 3940, 3966], 'wishes': [134], 'thank': [136], 'members': [138], 'Working': [141], 'Group': [142, 1876], 'Poppy': [144, 317, 362, 861, 1677, 3981], 'seeds:': [145], 'Andrew': [148], 'Cockburn,': [149], 'Birgit': [152], 'Dusemund,': [153], 'Fürst': [155], 'Jan-Willem': [157], 'der': [159, 810, 1402, 1431], 'Laan': [160, 2435], 'preparatory': [163], 'work': [164], 'scientific': [167, 196, 400], 'opinion': [168, 401], 'hearing': [171], 'expert': [172], 'éva': [173], 'Németh-Zámboriné,': [174], 'staff:': [177], 'Katleen': [178], 'Baert,': [179], 'Gina': [180], 'Cioacata,': [181], 'José': [182], 'Cortinas': [183], 'Abrahantes,': [184], 'Jean-Lou': [185], 'Dorne': [186], 'Liisa': [188], 'Valsta': [189], 'support': [192], 'provided': [193, 210], 'opinion.': [197], 'CONTAM': [199, 500], 'acknowledges': [201], 'all': [202], 'European': [203, 226, 246, 388, 392, 2328, 2827, 2848, 3429, 3850], 'competent': [204], 'authorities': [205], 'other': [207, 2098, 2378], 'stakeholders': [208], 'that': [209, 486, 547, 579], 'occurrence': [213], 'data': [214, 221, 583], 'food': [216, 466, 2816], 'supported': [218], 'consumption': [220], 'collection': [222], 'Comprehensive': [225, 2826, 2847], 'Consumption': [228, 2829, 2850], 'Database.': [229, 2830], 'Adoption': [230], 'date:': [231, 236], '5': [232], 'October': [233], 'Published': [235], '8': [237], 'Question': [240], 'number:': [241], 'EFSA-Q-2010-00961': [242], 'On': [243], 'request': [244, 2789], 'from:': [245], 'Commission': [247, 389], 'AboutPDF': [248], 'ToolsExport': [249], 'citationAdd': [250], 'favoritesTrack': [252], 'citation': [253], 'ShareShare': [254], 'Give': [255], 'accessShare': [256, 259], 'full': [257], 'text': [258], 'full-text': [260, 275, 299], 'accessPlease': [261], 'review': [262, 2072, 2418, 3809, 3988], 'our': [263], 'Terms': [264, 287], 'Conditions': [266, 289], 'Use': [268, 1864, 1874, 2843], 'check': [270], 'box': [271], 'below': [272, 295], 'share': [274, 297], 'version': [276, 300], 'article.I': [278], 'have': [279], 'read': [280], 'accept': [282], 'Wiley': [284], 'Online': [285], 'Library': [286], 'UseShareable': [291], 'LinkUse': [292], 'link': [294], 'a': [298, 313, 377, 399, 423, 554, 594, 848, 1304, 1478, 1828, 1839, 2138, 2257, 2417, 2763, 2788, 3963, 3984], 'article': [303], 'with': [304, 374, 573, 593, 1208, 1531, 1636, 1729, 1953, 2304, 2934, 2982, 3739, 3844], 'your': [305], 'friends': [306], 'colleagues.': [308], 'Learn': [309], 'more.Copy': [310], 'URL': [311], 'Share': [312], 'linkShare': [314], 'onFacebookTwitterLinkedInRedditWechat': [315], 'Abstract': [316], 'are': [319, 329], 'obtained': [320], 'from': [321, 431, 510, 541, 865, 1236, 1258, 1285, 1321, 1369, 1838, 2790, 2881, 3713], '(Papaver': [325, 2479, 3892], 'somniferum': [326, 2480, 2566, 2980, 3893], 'L.).': [327], 'They': [328], 'used': [330, 1207, 1980], 'bakery': [332, 448], 'products,': [333], 'top': [335], 'dishes,': [337], 'fillings': [339], 'cakes': [341], 'desserts': [344], 'produce': [347], 'edible': [348], 'oil.': [349], 'plant': [353], 'contains': [354], 'narcotic': [355, 2066, 3201], 'such': [357], 'as': [358, 376, 1074, 1524, 2657], 'morphine': [359, 497, 540, 624, 1308, 1523, 1830, 2002, 2129, 2160, 2447, 2624, 2741, 2955, 3047, 3112, 3143, 3423, 3528, 3761], 'codeine.': [361], 'do': [364], 'not': [365, 586], 'contain': [366], 'alkaloids,': [369, 435, 2665], 'but': [370], 'can': [371, 550], 'become': [372], 'contaminated': [373], 'result': [378], 'insect': [380], 'damage,': [381], 'or': [382], 'through': [383], 'poor': [384], 'harvesting': [385], 'practices.': [386], 'asked': [390], 'Safety': [394, 2779, 2808, 2840], 'Authority': [395], '(EFSA)': [396], 'provide': [398], 'intended': [418], 'human': [420, 1482, 2103, 2957, 3123], 'consumption.': [421], 'Following': [422], 'call': [424], 'data,': [426], 'received': [428], 'results': [430, 1837], 'analyses': [432], 'primarily': [436], 'morphine,': [437, 912], 'codeine,': [438, 913, 3588], 'thebaine,': [439], 'papaverine': [440, 647, 1042, 1047, 2349], 'noscapine,': [442, 847], 'samples': [444, 467, 572, 592], 'seeds,': [447, 1311], 'products': [449, 1073], 'baking': [451], 'ingredients.': [452], 'Based': [453], 'relative': [456], 'prevalence': [457], 'present': [461], 'seed': [464, 545, 571, 591, 941, 1371, 1548, 1678, 3591, 3982], 'analysed,': [468], 'their': [471, 915, 1983], 'pharmacological': [472, 1075, 3109, 3465], 'potency,': [473], '(CONTAM': [483], 'Panel)': [484], 'concluded': [485], 'risk': [488, 566, 2653], 'assessment': [489, 567, 2347, 2654, 3784, 3926], 'could': [490], 'be': [491, 551, 587, 1206], 'based': [492, 2766], 'dietary': [494, 537], 'exposure': [495, 538, 2130, 2445], 'alone.': [498], 'applied': [502, 2819], 'an': [503, 525, 574, 1845, 2882, 2887], 'uncertainty': [504], 'factor': [505, 2869, 2885, 4034], '3': [507], 'establish': [509], 'lowest': [512], 'known': [513], 'single': [514, 555], 'oral': [515], 'therapeutic': [516], 'dose': [517, 528, 2258], '30': [519], 'µg': [520], 'morphine/kg': [521, 533], 'body': [522], 'weight': [523], '(b.w.)': [524], 'acute': [526, 3296], 'reference': [527], '(ARfD)': [529], '10': [531], 'μg': [532], 'b.w.': [534], 'Estimates': [535], 'foods': [542], 'containing': [543], 'demonstrate': [546], 'ARfD': [549], 'exceeded': [552], 'during': [553], 'serving': [556], 'some': [558, 1978], 'consumers,': [559], 'particularly': [560], 'children,': [561], 'across': [562], 'EU.': [564], 'This': [565], 'relates': [568], 'alkaloid': [575, 597, 1134, 2562], 'profile': [576], 'comparable': [577], 'submitted': [582], 'should': [585, 1205], 'extrapolated': [588], 'qualitatively': [595], 'different': [596, 1140], 'profile.': [598], 'References': [599], 'Abernethy': [600, 2249], 'AP,': [601, 2250], 'Currow': [602, 2232], 'DC,': [603, 2233], 'Frith': [604, 2242], 'P,': [605, 1130, 1563, 1565, 1594, 1596, 2029, 2202, 2208, 2241, 2243, 2700, 3158, 3359, 3627, 4007], 'Fazekas': [606], 'BS,': [607], 'McHugh': [608], 'A': [609, 876, 1182, 1362, 1879, 2193, 2555, 3807], 'Bui': [611], 'C,': [612, 2027, 2235, 3095, 3097, 3361, 3779, 4002], '2003.': [613, 907, 1197, 1396, 1399, 1544, 2930, 4008], 'Randomised,': [614], 'double': [615], 'blind,': [616], 'placebo': [617], 'controlled': [618, 1479], 'crossover': [619], 'trial': [620, 1843], 'sustained': [622], 'release': [623], 'management': [627, 1200, 3817], 'refractory': [629, 1202], 'dyspnoea.': [630, 3819], 'BMJ,': [631, 1003, 1210], '327,': [632, 1211], '523–': [633], '528.': [634], 'Acosta': [635, 2343], 'D,': [636, 2344, 2464, 2528, 2945, 2995, 3634, 3879, 3886], 'Anuforo': [637], 'DC': [638], 'Smith': [640], 'RV,': [641], '1980.': [642], 'Cytotoxicity': [643, 3732], 'acetaminophen': [645], 'primary': [649, 2355], 'cultures': [650, 2356], 'rat': [652, 676, 2358], 'hepatocytes.': [653, 2359], 'Toxicology': [654], 'Applied': [656, 2570], 'Pharmacology,': [657, 855, 1377, 2332, 2894, 3127, 3971], '53,': [658], '306–': [659], '314.': [660], 'Adams': [661], 'ML,': [662], 'Sewing': [663], 'B,': [664, 1123, 2239, 2315, 2645, 3022, 3286, 3954], 'Forman': [665], 'JB,': [666], 'Meyer': [667, 1992], 'ER': [668], 'Cicero': [670, 1990], 'TJ,': [671, 1991], '1993.': [672, 1783, 2175], 'Opioid-induced': [673], 'suppression': [674], 'testicular': [677], 'function.': [678], 'Journal': [680, 707, 988, 1373, 1507, 1553, 1849, 1907, 1958, 2142, 2222, 2263, 2329, 2423, 2542, 2568, 2714, 2832, 2856, 3207, 3323, 3385, 3488, 3593, 3764, 3788, 3851, 3941, 3967], 'Pharmacology': [682, 709, 1750, 1909, 3511, 3766, 3943, 4022], 'Experimental': [684, 711, 1469, 1793, 1911, 2190, 3768, 3945], 'Therapeutics,': [685, 712, 1752, 1773, 1912, 3272, 3769, 3946, 4024], '266,': [686], '323–': [687], '328.': [688], 'Adler': [689], 'TK,': [690], 'Fujimoto': [691], 'JM,': [692, 2924], 'Way': [693], 'EL': [694], 'Baker': [696], 'EM,': [697], '1955.': [698], 'metabolic': [700], 'fate': [701], 'codeine': [703, 2622, 2712, 3319, 3530], 'man.': [705, 1050, 1748], '114,': [713], '251–': [714], '262.': [715], 'AHFS': [716, 740, 746], '(American': [717, 741], 'Hospital': [718, 723, 742, 751], 'Formulary': [719, 724, 743, 752], 'Service),': [720, 744], '1995.': [721, 1921, 2156, 3334], 'American': [722, 729, 750, 757, 3206], 'Service.': [725, 753], 'Ed': [726, 754, 1111, 1349, 1795, 2192, 2677], 'GK.': [727, 755], 'McEvoy': [728, 756], 'Society': [730, 758], 'Health-System': [732, 760], 'Pharmacists.': [733, 761], '7272': [734, 762], 'Wisconsin': [735, 763], 'Avenue,': [736, 764], 'Bethesda,': [737, 765], 'MD': [738, 766], '20814.': [739, 767], '2007.': [745, 749, 841, 1272, 1497, 1676, 2410, 2534, 3226, 3916], 'Drug': [747, 1686, 2107], 'Information,': [748], 'Aktories': [768], 'K,': [769, 776, 1358, 1390, 1419, 1444, 1666, 2609, 2722, 3002, 3725], 'Förstermann': [770, 2998], 'U,': [771, 1388, 1417, 2558, 2726], 'Hofmann': [772, 2725], 'F': [773], 'Starke': [775, 3001], '2009.': [777, 875, 1062, 1154, 2037, 2559, 3780], 'Allgemeine': [778, 3004], 'und': [779, 782, 820, 1220, 1242, 1264, 1404, 1433, 2309, 2474, 2486, 3005, 3008, 3234, 3248], 'spezielle': [780, 3006], 'Pharmakologie': [781, 3007], 'Toxikologie.': [783, 3009], '10th': [784], 'edition,': [785, 3470], 'Elsevier,': [786], 'München,': [787, 3013], 'Germany.': [788, 1590, 1621], 'Amann': [789], 'T': [790, 2275, 2594], 'Zenk': [792, 3105], 'MH,': [793, 3106], '1996.': [794, 1468, 3460], 'Endogenes': [795], 'Morphin.': [796], 'Deutsche': [797], 'Apotheker': [798], 'Zeitung,': [799], '136,': [800], '17–': [801], '25.': [802], 'Andresen': [803], 'H': [804, 1448], 'Schmoldt': [806], 'A,': [807, 833, 1061, 1646, 1716, 2174, 2204, 2551, 2589, 2611, 2650, 2728, 2899, 3027, 3625, 3638, 3642, 3660, 3672, 3723, 3829, 3859], '2004.': [808, 934, 1228, 1577, 3084], 'Führt': [809], 'Verzehr': [811], 'von': [812, 1656, 3230, 3250], 'Mohnsamen': [813, 3233], 'zu': [814, 2292, 2475], 'positiven': [815], 'Opiatbefunden': [816], 'Urin,': [818], 'Blut': [819], 'Haaren?': [821], 'Blutalkohol,': [822], '4,': [823, 2427, 3855], '191–': [824], '202.': [825], 'Aneja': [826], 'R,': [827, 1442, 1576, 1607, 1670, 3436], 'Dhiman': [828], 'N,': [829, 928, 1920, 3093, 3347], 'Idnani': [830], 'J,': [831, 1099, 1121, 1360, 1365, 1446, 1467, 2607, 3216, 3357, 3367, 3621, 3636, 3681, 3881], 'Awasthi': [832], 'Arora': [834], 'SK,': [835], 'Chandra': [836], 'R': [837, 1672, 1917], 'Joshi': [839], 'HC,': [840], 'Preclinical': [842], 'pharmacokinetics': [843], 'bioavailability': [845], 'tubulin-binding': [849], 'anticancer': [850], 'agent.': [851], 'Cancer': [852], 'Chemotherapy': [853], '60,': [856], '831–': [857], '839.': [858], 'Anonymous,': [859], '2011.': [860, 2251, 2866, 3107], 'Seed': [862], 'Oil.': [863], 'Available': [864, 1235, 1257, 1284, 1320, 3712], 'www.recipetips.com/glossary-term/t-36310/poppy-seed-oil.asp.': [866], 'Retrieved': [867], '12.04.2011.': [869], 'Argoff': [870], 'CE': [871], 'Silvershein': [873], 'DI,': [874], 'comparison': [877], 'long-': [879], 'short-acting': [881], 'opioids': [882, 1948, 1981, 2253, 2538, 3377, 3814, 3922], 'treatment': [885, 1526, 2299, 2870], 'chronic': [887, 1954, 2255, 3845], 'noncancer': [888], 'pain:': [889, 1836, 3380], 'tailoring': [890], 'therapy': [891], 'meet': [893], 'patient': [894], 'needs.': [895], 'Mayo': [896], 'Clinic': [897], 'Proceedings,': [898, 2602, 3995], '84,': [899, 3388], '602–': [900], '612.': [901], 'Armstrong': [902], 'SC': [903], 'Cozza': [905], 'KL,': [906], 'Pharmacokinetic': [908, 2324], 'drug': [909, 982], 'interactions': [910, 3054], 'derivatives:': [916], 'Theory': [917], 'clinical': [919, 3584, 3938, 4017], 'reality,': [920], 'part': [921], 'I.': [922, 1167, 1350, 3482], 'Psychosomatics,': [923], '44,': [924, 2603], '167–': [925, 1663], '171.': [926], 'Azcan': [927], 'Kalender': [929], 'BO': [930], 'Kara': [932], 'M,': [933, 1520, 1651, 1743, 2200, 2245, 2273, 2322, 3225, 3293, 3349, 3574, 3632, 3648, 3654, 3658, 3668, 3716, 3719, 3721, 3730], 'Investigation': [935], 'Turkish': [937], 'oils.': [942], 'Chemistry': [943], 'Natural': [945], 'Compounds,': [946], '40,': [947], '370–': [948], '372.': [949, 2025], 'Badr': [950], 'FM': [951], 'Rabouh': [953], 'SA,': [954], '1983.': [955, 3041], 'Effects': [956, 1941, 2000, 2176, 2442], 'morphine-sulfate': [958], 'germ-cells': [961], 'male-mice.': [963], 'Teratogenesis': [964], 'Carcinogenesis': [965], 'Mutagenesis,': [967, 3182], '3,': [968, 2547], '19–': [969], '26.': [970], 'Bandstra': [971], 'ES,': [972], 'Morrow': [973], 'CE,': [974], 'Mansoor': [975], 'E': [976, 1573, 1604], 'Accornero': [978], 'VH,': [979], '2010.': [980, 1181, 1608, 1871, 1884, 2279, 2651], 'Prenatal': [981], 'exposure:': [983], 'infant': [984], 'toddler': [986], 'outcomes.': [987], 'Addictive': [990], 'Diseases,': [991], '29,': [992, 3597, 4041], '245–': [993], '258.': [994], 'Barnes': [995], 'PJ': [996, 2341, 2905], 'Chung': [998], 'KF,': [999], '1989.': [1000, 1015, 2952, 3421], 'Difficult': [1001], 'asthma.': [1002], '299,': [1004], '695–': [1005], '698,': [1006], 'reply': [1008, 1214], '1031-1032.': [1009], 'Baselt': [1010], 'RC': [1011], 'Cravey': [1013], 'RH,': [1014], 'Disposition': [1016], 'toxic': [1018], 'drugs': [1019, 1631], 'chemicals': [1021], 'man,': [1023], '3rd': [1024], 'edition.': [1025, 2387], 'Chicago.': [1026], 'Year': [1027], 'Book': [1028], 'Medical': [1029, 1226, 1248, 1270], 'Publishers': [1030], 'Inc.': [1031], 'Belpaire': [1032], 'FM,': [1033, 1462], 'Rosseel': [1034], 'MT': [1035], 'Bogaert': [1037], 'MG,': [1038, 3220], '1978.': [1039, 3731], 'Metabolism': [1040, 2108], 'IV.': [1043], 'Urinary': [1044], 'elimination': [1045], 'metabolites': [1048, 2353, 3113], 'Xenobiotica,': [1051], '8,': [1052], '297–': [1053], '300.': [1054], 'Berényi': [1055], 'S,': [1056, 1384, 1413, 2237, 2616, 2724, 2757, 2929, 3156, 3355, 3551, 3644, 3650, 3656, 3674], 'Csutorás': [1057], 'C': [1058, 2370, 2948], 'Sipos': [1060], 'Recent': [1063], 'developments': [1064], 'chemistry': [1067], 'thebaine': [1069, 2986, 3506], 'its': [1071, 1500, 1505], 'transformation': [1072], 'targets.': [1076], 'Current': [1077], 'Medicinal': [1078, 1106], 'Chemistry,': [1079, 3328, 3541], '16,': [1080, 1146, 1753], '3215–': [1081], '3242.': [1082], 'Bergstrom': [1083], 'L,': [1084, 1817, 3363, 3623, 3640, 3662, 3670], '1994.': [1085], 'Nutrient': [1086], 'Losses': [1087], 'Gains': [1089], 'Preparation': [1092], 'Foods.': [1094, 1348], 'Livsmedelsverket': [1095], 'Rapport': [1096], '32/94.': [1097], 'Bernáth': [1098, 1113, 1120, 1149, 1176], '1998.': [1100, 1345, 1452, 2093, 2441], 'Poppy:': [1101], 'genus': [1103], 'Papaver.': [1104], 'Series:': [1105], 'Aromatic': [1108], 'Plants-Industrial': [1109], 'Profiles.': [1110], 'J.': [1112], 'Harwood': [1114, 1667], 'Academic': [1115], 'Publishers,': [1116], 'Amsterdam,': [1117], 'Netherlands.': [1119], 'Dános': [1122], 'Veres': [1124], 'T,': [1125, 1668, 2317, 3569, 3629, 3646], 'Szántó': [1126], 'J': [1127, 1150, 1164, 1177, 1392, 1421, 1888, 2697, 3160, 3883], 'Tétényi': [1129], '1988.': [1131, 3136], 'Variation': [1132], 'production': [1135], 'ecotypes-responses': [1138], 'environments.': [1141], 'Biochemical': [1142, 3126], 'Systematics': [1143], 'Ecology,': [1145], '171–': [1147], '178.': [1148], 'Németh': [1152, 1179], 'E,': [1153, 1180, 1386, 1415, 1567, 1598, 2060, 2278, 3351, 3441, 3666], 'Poppy,': [1155], 'Oil': [1156], 'Crops.': [1157], 'Handbook': [1158, 1791, 2188], 'Plant': [1160], 'Breeding': [1161], '4.': [1162], 'Eds': [1163, 2388, 3275], 'Vollmann': [1165], 'Rajcan': [1168], 'Springer': [1169, 1435, 1457, 3446], 'Science': [1170], 'Business': [1172], 'Media,': [1173], '449–': [1174], '468.': [1175, 3904], 'mák.': [1183], 'Termesztés': [1184], 'és': [1185], 'receptek.': [1186], 'CSER,': [1187], 'Kiadó.': [1188], 'Budapest.': [1189], '88': [1190], 'pp.': [1191, 1356, 2836, 2860], 'Berrill': [1192], 'JW': [1193, 2436], 'Linnasne': [1195], 'SJ,': [1196], 'Morphine': [1198, 1367, 1498, 1745, 2508, 2591, 3317, 3335, 3374, 3405, 3836], 'dyspnoea:': [1203], 'opiates': [1204], 'caution.': [1209], '1288;': [1212], '1288-1289.': [1215], 'BfArM': [1216, 1238, 1260], '(Bundesinstitut': [1217, 1239, 1261, 1288, 1324], 'für': [1218, 1240, 1262, 1289, 1325, 1336, 2484, 2491], 'Arzneimittel': [1219, 1241, 1263], 'Medizinprodukte-Federal': [1221, 1243, 1265], 'Institute': [1222, 1244, 1266, 1291, 1327], 'Drugs': [1224, 1246, 1268, 1701, 3556], 'Devices),': [1227, 1249, 1271], 'Fachinformationen,': [1229, 1251, 1273], 'Mustertexte:': [1230, 1252, 1274], 'Morphin,': [1231], 'Lösung,': [1232], 'Filmtablette,': [1233], 'Brausetablette.': [1234], 'www.bfarm.de.': [1237, 1259, 1286], '2005.': [1250, 1319, 2127, 3575], 'Morphin': [1253, 1657, 3231], 'Retardtablette,': [1254], 'Retardkapsel,': [1255], 'Retardgranulat.': [1256], 'Codein': [1275, 1280], '(wasserfreie': [1276], 'Base)': [1277], 'als': [1278], 'Codeinphosphathemihydrat;': [1279], '1': [1281, 2877], 'H2O;': [1282], 'Codeinphosphat.': [1283], 'BfR': [1287, 1296, 1312, 1323, 2652], 'Risikobewertung-Federal': [1290, 1326], 'Risk': [1293, 1329, 2671], 'Assessment),': [1294, 1330], '2005a.': [1295], 'recommends': [1297], 'provisional': [1298], 'daily': [1299], 'upper': [1300], 'intake': [1301, 1368], 'level': [1302], 'guidance': [1305], 'value': [1306], 'Health': [1313], 'Assessment': [1314, 2672], 'No.': [1315], '012/2006,': [1316], '27': [1317, 2835], 'December': [1318], 'www.bfr.bund.de/cm/245/bfr_recommends_provisional_daily_upper_intake_level_and_a_guidance_value_for_morphine_in_poppy_seeds.pdf.': [1322], '2005b.': [1331], 'Backmohn': [1332], 'ist': [1333], 'kein': [1334], 'Schlafmittel': [1335], 'Säuglinge;': [1337], 'BfR-Pressemitteilung': [1338], 'Nr.': [1339], '12': [1340], 'vom': [1341], '29.04.2005.': [1342], 'Biruté': [1343, 1351], 'I,': [1344, 2469, 3615, 3617, 3652, 3877], 'Lithuanian': [1346], 'Traditional': [1347], 'Baltos': [1352], 'Lankos,': [1353], 'Lithuania.': [1354], '109': [1355], 'Bjerver': [1357], 'Jonsson': [1359], 'Nilsson': [1361], 'Schuberth': [1364], '1982.': [1366, 2323], 'food.': [1372], 'Pharmacy': [1375, 3969], '34,': [1378], '798–': [1379], '801.': [1380], 'Blaschek': [1381, 1410, 1439], 'W,': [1382, 1411, 1440, 1815, 2993, 2997], 'Ebel': [1383, 1412], 'Hackenthal': [1385, 1414], 'Holzgrabe': [1387, 1416], 'Keller': [1389, 1418, 1443], 'Reichling': [1391, 1420, 1445], 'Schulz': [1394, 1423], 'V,': [1395, 1424, 3372, 3567], 'Hager': [1397, 1426], 'ROM': [1398, 1427], 'Hagers': [1400, 1429, 1453], 'Handbuch': [1401, 1430, 1454], 'Drogen': [1403, 1432], 'Arzneistoffe.': [1405, 1434], 'Springer0': [1406], 'Medizin': [1407, 1436, 1458], 'Verlag,': [1408, 1437, 1459, 3447, 3612], 'Heidelberg.': [1409, 1438, 1460, 3257, 3448], '2006.': [1425, 1428, 1722, 1765, 2374, 2758, 2781, 3980], 'Hänsel': [1441, 3435], 'Rimpler': [1447], 'Schneider': [1450], 'G,': [1451, 1569, 1571, 1600, 1602, 1675, 2036, 2213, 2373, 2733, 3154, 3218], '5.': [1455, 3086], 'Auflage,': [1456, 3074, 3087, 3253, 3445, 3608], 'Borgbjerg': [1461], 'Nielsen': [1463], 'K': [1464, 3753], 'Franks': [1466], 'pain': [1470, 3297], 'stimulates': [1471], 'respiration': [1472], 'attenuates': [1474], 'morphine-induced': [1475], 'respiratory': [1476, 2379, 3407], 'depression:': [1477], 'study': [1480, 2296], 'volunteers.': [1483, 2744], 'Pain,': [1484, 1870, 1960], '64,': [1485], '123–': [1486, 2171], '128.': [1487], 'Bosch': [1488], 'ME,': [1489], 'Sanchez': [1490], 'AR,': [1491], 'Rojas': [1492], 'FS': [1493], 'Ojeda': [1495], 'CB,': [1496], 'metabolites:': [1501], 'analytical': [1502], 'methodologies': [1503], 'determination.': [1506], 'Pharmaceutical': [1509, 2716, 3490], 'Biomedical': [1511], 'Analysis,': [1512], '43,': [1513], '799–': [1514], '815.': [1515], 'Boyd': [1516], 'KJ': [1517], 'Kelly': [1519], '1997.': [1521], 'Oral': [1522], 'symptomatic': [1525], 'dyspnoea': [1528], 'patients': [1530, 1952, 3843], 'advanced': [1532, 3427], 'cancer.': [1533], 'Palliative': [1534], 'Medicine,': [1535, 2049, 2147, 2426, 2546], '11,': [1536], '277–': [1537], '281.': [1538], 'Bozan': [1539], 'B': [1540, 2406, 3222], 'Temelli': [1542], 'F,': [1543, 1561, 1592, 1972, 2584, 3266, 3345], 'Extraction': [1545], 'oil': [1549], 'using': [1550], 'supercritical': [1551], 'CO2.': [1552], 'Science,': [1556], '68,': [1557], '422–': [1558], '426.': [1559], 'Bracher': [1560, 1591], 'Heisig': [1562, 1593], 'Langguth': [1564, 1595], 'Mutschler': [1566, 1597], 'Rücker': [1568, 1599], 'Scriba': [1570, 1601], 'Stahl-Biskup': [1572, 1603], 'Troschütz': [1575, 1606], 'Kommentar': [1578, 1609], 'zum': [1579, 1610], 'Europäischen': [1580, 1611], 'Arzneibuch': [1581, 1612], '(Commentary': [1582, 1613], 'Pharmacopoeia': [1585, 1616], 'Europaea),': [1586, 1617], 'Wissenschaftliche': [1587, 1618, 3075, 3088], 'Verlagsgesellschaft,': [1588, 1619], 'Stuttgart,': [1589, 1620], 'Bracken': [1622], 'MB': [1623], 'Holford': [1625], 'TR,': [1626, 2092, 2402], '1981.': [1627, 3398, 3502], 'Exposure': [1628, 2797, 2853, 3685], 'prescribed': [1630], 'pregnancy': [1633, 1703], 'association': [1635], 'congenital': [1637], 'malformations.': [1638, 3481], 'Obstetrics': [1639, 3209], 'Gynecology,': [1641, 3211], '58,': [1642], '336–': [1643], '344.': [1644], 'Bratina': [1645], 'Perpar': [1647], 'M': [1648, 2389, 3132, 3727, 3776], 'Tišler': [1650], '1957.': [1652], 'Beitrag': [1653], 'zur': [1654, 2283, 2472, 3228], 'Bestimmung': [1655], 'Mohnkapseln.': [1659], 'Microchimica': [1660], 'Acta,': [1661], '45,': [1662, 2522, 2773], '173.': [1664], 'Braye': [1665], 'Inder': [1669], 'Beasley': [1671], 'Robinson': [1674], 'tea': [1679], 'opiate': [1681, 3057], 'abuse': [1682], 'New': [1684, 1776, 2045, 3282], 'Zealand.': [1685], 'Alcohol': [1688], 'Review,': [1689], '26,': [1690, 2111, 2366], '215–': [1691], '219.': [1692], 'Briggs': [1693], 'GG,': [1694], 'Freeman': [1695], 'RK': [1696], 'Sumner': [1698], 'JY,': [1699], '1986.': [1700, 2617], 'lactation.': [1705], '2nd': [1706, 2386], 'ed.': [1707, 3274], 'Williams': [1708], '&': [1709, 2145, 2226, 2363, 2688, 3011, 3462], 'Wilkins.': [1710], '102–': [1711], '103c.': [1712], 'Brown': [1713], 'KA,': [1714], 'Laferriere': [1715], 'Lakheeram': [1717], 'I': [1718], 'Moss': [1720], 'IR,': [1721], 'Recurrent': [1723], 'hypoxemia': [1724], 'children': [1726], 'is': [1727], 'associated': [1728, 2933], 'increased': [1730], 'analgesic': [1731, 2738], 'sensitivity': [1732], 'opiates.': [1734, 2913, 3871], 'Anesthesiology,': [1735], '105,': [1736], '665–': [1737], '669.': [1738], 'Brunk': [1739], 'SF': [1740], 'Delle': [1742], '1974.': [1744, 3246], 'metabolism': [1746], 'Clinical': [1749, 1957, 2227, 2331, 2544, 2771, 3540, 4021], '51–': [1754], '57.': [1755], 'Brunton': [1756], 'LL,': [1757], 'Lazo': [1758], 'JS,': [1759], 'Parker': [1760], 'KL': [1761], 'Gilman': [1763, 3258, 3458], 'AG,': [1764, 3259, 3459], 'Goodman': [1766, 3260, 3276, 3461], "Gilman's": [1768, 3463], 'Pharmacological': [1770, 3269], 'Basis': [1771, 3270], '11thed.': [1774], 'McGraw-Hill,': [1775], 'York.': [1777], 'Bryant': [1778], 'HU': [1779], 'Holaday': [1781], 'JW,': [1782, 3397], 'Opioids': [1784, 1789, 1866, 2178, 2186], 'immunologic': [1786], 'Processes.': [1787], 'In:': [1788, 2185, 2381, 2670], 'II,': [1790, 2187], 'Pharmacology.': [1794, 2191], 'A.': [1796], 'Herz': [1797], 'Springer-Verlag,': [1798, 2195], 'Berlin,': [1799, 2196], '361–': [1800], '392.': [1801], 'Caldwell': [1802], 'JR,': [1803, 3365], 'Rapoport': [1804], 'RJ,': [1805, 1967, 2922], 'Davis': [1806, 2340, 2369], 'JC,': [1807, 2337, 3906], 'Offenberg': [1808], 'HL,': [1809, 3315], 'Marker': [1810], 'HW,': [1811], 'Roth': [1812], 'SH,': [1813], 'Yuan': [1814], 'Eliot': [1816], 'Babul': [1818], 'N': [1819, 2730], 'Lynch': [1821], 'PM,': [1822], '2002.': [1823, 1940, 2470, 3806, 3835], 'Efficacy': [1824], 'safety': [1826, 2683], 'once-daily': [1829], 'formulation': [1831], 'chronic,': [1833], 'moderate-to-severe': [1834], 'osteoarthritis': [1835], 'randomized,': [1840], 'placebo-controlled,': [1841], 'double-blind': [1842], 'open-label': [1846], 'extension': [1847], 'trial.': [1848], 'Pain': [1851, 2265], 'Symptom': [1853, 2267], 'Management,': [1854, 2268, 3791], '23,': [1855], '278–': [1856], '291.': [1857], 'Canadian': [1858], 'Guideline': [1859, 1875], 'Safe': [1861], 'Effective': [1863], 'Chronic': [1868], 'Non-Cancer': [1869], 'National': [1872, 2631], 'Opioid': [1873, 3790], '(NOUGG),': [1877], 'Part': [1878], 'B.': [1881], 'April': [1882], '30,': [1883, 2990], 'Caraco': [1885], 'Y,': [1886], 'Sheller': [1887], 'Wood': [1890], 'AJ,': [1891, 2967], '1999.': [1892, 2214, 3442], 'Impact': [1893], 'ethnic': [1895], 'origin': [1896], 'quinidine': [1898], 'coadministration': [1899], "codeine's": [1901], 'disposition': [1902], 'pharmacodynamic': [1904], 'effects.': [1905], '290,': [1913], '413–': [1914], '422.': [1915], 'Carbajal': [1916], 'Simon': [1919], 'Sedation': [1922], 'analgesia': [1924], 'children.': [1926, 2770], 'Archives': [1927, 2914, 3698], 'de': [1928, 2520, 3610], 'Pediatrie,': [1929], '2,': [1930], '1089–': [1931], '1096.': [1932], 'Chapman': [1933], 'SL,': [1934], 'Byas-Smith': [1935], 'MG': [1936], 'Reed': [1938], 'BA,': [1939], 'intermediate-': [1943], 'long-term': [1945, 2935], 'use': [1946, 3812], 'cognition': [1950], 'pain.': [1955, 3414], '18,': [1961], 'S83–': [1962], '90.': [1963], 'Chen': [1964], 'ZR,': [1965], 'Irvine': [1966], 'Somogyi': [1968], 'AA': [1969], 'Bochner': [1971], '1991.': [1973, 3164], 'Mu': [1974], 'receptor': [1975], 'binding': [1976, 3958], 'commonly': [1979], 'metabolites.': [1984], 'Life': [1985], 'Sciences,': [1986, 2717, 3491], '48,': [1987], '2165–': [1988], '2171.': [1989], 'ER,': [1993, 3908], 'Bell': [1994], 'RD': [1995], 'Koch': [1997], 'GA,': [1998], '1976.': [1999, 3316], 'methadone': [2004, 2449], 'serum': [2006, 3532], 'testosterone': [2007], 'luteinizing': [2009], 'hormone': [2010], 'levels': [2011], 'secondary': [2015], 'sex': [2016], 'organs': [2017], 'male': [2020], 'rat.': [2021, 2627], 'Endocrinology,': [2022], '98,': [2023], '367–': [2024], 'Ciszkowski': [2026], 'Madadi': [2028], 'Phillips': [2030], 'MS,': [2031, 2533], 'Lauwers': [2032], 'AE': [2033], 'Koren': [2035], 'Codeine,': [2038], 'ultrarapid-metabolism': [2039], 'genotype,': [2040], 'postoperative': [2042], 'death.': [2043], 'England': [2046], 'Jornal': [2047], '361,': [2050], '827–': [2051], '828.': [2052], 'Cobrinik': [2053], 'RW,': [2054, 2117], 'Hood': [2055], 'RT,': [2056], 'Jr.': [2057, 3474], 'Chusid': [2059], '1959.': [2061], 'effect': [2063, 2536, 2739], 'maternal': [2065], 'addiction': [2067], 'newborn': [2070], 'infant;': [2071], 'literature': [2074], 'report': [2076, 3986], '22': [2078], 'cases.': [2079], 'Pediatrics,': [2080], '24,': [2081, 3329], '288–': [2082], '304.': [2083], 'Coffman': [2084], 'BL,': [2085], 'King': [2086, 2902], 'CD,': [2087, 2497, 3756], 'Rios': [2088], 'GR': [2089], 'Tephly': [2091], 'glucuronidation': [2095], 'opioids,': [2097], 'xenobiotics,': [2099], 'androgens': [2101], 'UGT2B7Y(268)': [2104], 'UGT2B7H(268).': [2106], 'Disposition,': [2110], '73–': [2112], '77.': [2113], 'Collins': [2114], 'LR,': [2115], 'Hall': [2116], 'Dajani': [2118], 'NK,': [2119], 'Wendel': [2120], 'PJ,': [2121], 'Lowery': [2122], 'CL': [2123], 'Kay': [2125], 'HH,': [2126], 'Prolonged': [2128], 'utero': [2132], 'causes': [2133], 'fetal': [2134, 3480, 4036], 'placental': [2136], 'vasoconstriction:': [2137], 'case': [2139, 3985], 'report.': [2140], 'Maternal-Fetal': [2144], 'Neonatal': [2146], '17,': [2148], '417–': [2149], '421.': [2150], 'Couch': [2151], 'DB': [2152], 'Sawant': [2154], 'SG,': [2155], 'clastogenicity': [2158], 'sulfate': [2161], 'vivo.': [2163], 'Brain': [2164, 3061], 'Immune': [2165], 'Axis': [2166], 'Substance': [2168], 'Abuse,': [2169], '373,': [2170], '129.': [2172], 'Cowan': [2173], 'spontaneous': [2181], 'Behavior': [2182], 'Animals.': [2184], 'Herz.': [2194], '393–': [2197], '428.': [2198, 2965], 'Crivellaro': [2199], 'Bonadonna': [2201], 'Dama': [2203], 'Senna': [2205], 'GE,': [2206], 'Mezzelani': [2207], 'Mistrello': [2209], 'G': [2210], 'Passalacqua': [2212], 'Severe': [2215], 'systemic': [2216], 'reactions': [2217], 'caused': [2218, 3031], 'seed.': [2221, 3034, 3322], 'Investigational': [2224], 'Allergology': [2225], 'Immunology,': [2228], '58–': [2230], '59.': [2231], 'McDonald': [2234], 'Oaten': [2236], 'Kenny': [2238], 'Allcroft': [2240], 'Briffa': [2244], 'Johnson': [2246, 3824], 'MJ': [2247], 'Once-daily': [2252], 'dyspnea:': [2256], 'increment': [2259], 'pharmacovigilance': [2261], 'study.': [2262, 3849], '42,': [2269, 3972], '388–': [2270], '399.': [2271], 'Dahlheim': [2272], 'Schwartz': [2274], 'Banffy-Josika': [2277], 'Nichtinterventionelle': [2280], 'multizentrische': [2281], 'Studie': [2282], 'Therapie': [2284], 'des': [2285], 'unproduktiven': [2286], 'Reizhustens': [2287], 'mit': [2288, 3236], 'Noscapin': [2289], 'im': [2290], 'Vergleich': [2291], 'Codein/Dihydrocodein': [2293], '(Non-interventional': [2294], 'multicentre': [2295], 'unproductive': [2301], 'dry': [2302], 'cough': [2303], 'noscapine': [2305, 3180], 'versus': [2306], 'codeine/dihydrocodeine).': [2307], 'Atemwegs-': [2308], 'Lungenkrankheiten,': [2310], '36,': [2311, 3416], '35–': [2312], '40.': [2313], 'Dahlström': [2314], 'Mellstrand': [2316], 'Lofdahl': [2318], 'CG': [2319], 'Johansson': [2321], 'properties': [2325, 3110], 'noscapine.': [2327], '22,': [2333], '535–': [2334], '539.': [2335], 'Davila': [2336], 'Reddy': [2338], 'CG,': [2339], '1990.': [2345, 3710, 3955], 'Toxicity': [2346], 'hydrochloride': [2350, 3865], 'papaverine-derived': [2352], 'In': [2360], 'Vitro': [2361], 'Cellular': [2362], 'Developmental': [2364], 'Biology,': [2365], '515–': [2367], '524.': [2368], 'Percy': [2372], 'Breathlessness,': [2375], 'cough,': [2376], 'problems.': [2380], 'ABC': [2382], 'palliative': [2384], 'care.': [2385], 'Fallon': [2390], 'G.': [2392], 'Hanks': [2393, 3332, 3342, 3391, 3419], 'BMJ': [2394], 'Publishing': [2395, 3280, 3561], 'Group,': [2396], 'London,': [2397], '13–': [2398], '16.': [2399], 'De': [2400, 2430, 3630, 3675], 'Jong': [2401], 'Veening': [2403], 'JG,': [2404, 3450], 'Olivier': [2405], 'Waldinger': [2408], 'MD,': [2409, 3308], 'Oxytocin': [2411], 'involvement': [2412, 3052], 'SSRI-induced': [2414], 'delayed': [2415], 'ejaculation:': [2416], 'animal': [2420], 'studies.': [2421], 'Sexual': [2425], '14–': [2428], '28.': [2429], 'Waal': [2431], 'EJ,': [2432, 3288], 'Van': [2433, 2438, 3679], 'Der': [2434], 'Loveren': [2439], 'H,': [2440, 2865, 3040], 'prolonged': [2444], 'vivo': [2452], 'parameters': [2453], 'immune': [2455], 'function': [2456], 'rats.': [2458, 3146, 3763], 'Toxicology,': [2459, 3596], '129,': [2460], '201–': [2461], '210.': [2462, 3065], 'Dejnega': [2463], 'Girsch': [2465], 'L': [2466], 'Kramberger': [2468], 'Betrachtungen': [2471], 'Saatgutproduktion': [2473], 'Saatgutregelungen': [2476], 'bei': [2477], 'Mohn': [2478], 'L.);': [2481], 'AGES-Österreichische': [2482], 'Agentur': [2483], 'Gesundheit': [2485], 'Ernährungs-sicherheit': [2487], 'GmbH': [2488, 2687], '/': [2489], 'Institut': [2490], 'Saatgut,': [2492], 'Wien.': [2493], 'Dillenburg': [2494], 'CF,': [2495], 'Kruel': [2496], 'Cerski': [2498], 'CT,': [2499], 'Edelweiss': [2500], 'MI,': [2501], 'Silva': [2502], 'TL': [2503], 'Schier': [2505], 'AS,': [2506], '2008.': [2507], 'does': [2509], 'no': [2510], 'promote': [2511], 'esophageal': [2512], 'carcinogenesis': [2513], 'rats': [2515], 'exposed': [2516], 'diethylnitrosamine.': [2518], 'Arquivos': [2519], 'Gastroenterologia,': [2521], '87–': [2523], '92.': [2524], 'Dimsdale': [2525], 'JE,': [2526], 'Norman': [2527], 'DeJardin': [2529], 'D': [2530, 2586, 3067, 3080, 3548, 4004], 'Wallace': [2532], 'sleep': [2540], 'architecture.': [2541], 'Sleep': [2545], '33–': [2548], '36.': [2549], 'Dittbrenner': [2550], 'Mock': [2552], 'HP,': [2553], 'Borner': [2554], 'Lohwasser': [2557], 'Variability': [2560], 'content': [2563], 'Papaver': [2565, 2979], 'L.': [2567], 'Botany': [2571], 'Quality-Angewandte': [2574], 'Botanik,': [2575], '82,': [2576], '103–': [2577], '107.': [2578], 'Donahoe': [2579], 'RM,': [2580], 'Madden': [2581], 'JJ,': [2582], 'Hollingsworth': [2583], 'Shafer': [2585], 'Falek': [2588, 2898], '1985.': [2590, 3267, 3284, 3860], 'depression': [2592, 3408], 'cell': [2595], 'E-rosetting:': [2596], 'definition': [2597], 'process.': [2600], 'Federation': [2601], '95–': [2604], '99.': [2605], 'Donnerer': [2606], 'Oka': [2608], 'Brossi': [2610], 'Rice': [2612], 'KC': [2613], 'Spector': [2615], 'Presence': [2618], 'formation': [2620], 'Proceedings': [2628], 'Academy': [2632], 'Sciences': [2634, 3562], 'United': [2637, 2974], 'States': [2638, 2975], 'America,': [2640, 3303], '83,': [2641], '4566–': [2642], '4567.': [2643], 'Dusemund': [2644], 'Appel': [2646], 'K-E': [2647], 'Lampen': [2649], 'ingredients': [2658], 'contaminants': [2660], 'food:': [2662], 'Quinine,': [2663], 'senecio': [2667], 'pyrrolizidine': [2668], 'alkaloids.': [2669], 'Phytochemicals': [2674], 'Food.': [2676], 'DFG': [2678], 'Senate': [2679], 'commission': [2680], '(SKLM).': [2684], 'Wiley-VCH': [2685], 'Verlag': [2686], 'Co.': [2689], 'KGaA,': [2690], 'Weinheim,': [2691], '382–': [2692], '390.': [2693], 'Ebbighausen': [2694], 'WOR,': [2695], 'Mowat': [2696], 'Vestergaard': [2699], '1973.': [2701], 'Mass': [2702], 'fragmentographic': [2703], 'detection': [2704], 'normorphine': [2706], 'urine': [2708, 3534], 'man': [2710], 'after': [2711, 3535], 'intake.': [2713], '62,': [2718], '146–': [2719], '148.': [2720], 'Eckhardt': [2721], 'Ammon': [2723], 'Riebe': [2727], 'Gugeler': [2729], 'Mikus': [2732], '2000.': [2734, 2973, 2991, 3028, 3294], 'Gabapentin': [2735], 'enhances': [2736], 'healthy': [2743], 'Anesthesia': [2745], 'Analgesia,': [2747], '91,': [2748], '185–': [2749], '191.': [2750], 'Edginton': [2751], 'AN,': [2752, 3798], 'Schmitt': [2753], 'W': [2754], 'Willmann': [2756], 'Development': [2759], 'evaluation': [2761], 'generic': [2764], 'physiologically': [2765], 'pharmacokinetic': [2767], 'model': [2768], 'Pharmacokinetics,': [2772], '1013–': [2774], '1034.': [2775], '(European': [2777, 2806, 2838], 'Authority),': [2780, 2809, 2841], 'Guidance': [2782], 'Committee': [2786], 'Uncertainties': [2794], 'Dietary': [2796, 3684], 'Assessment.': [2798, 2854], 'Journal,': [2801], '438,': [2802], '1–': [2803], '54.': [2804], '2011a.': [2810], 'Evaluation': [2811], 'FoodEx,': [2814], 'classification': [2817], 'system': [2818, 3198], 'development': [2822], '2011;': [2833], '9(3):1970.': [2834], '2011b.': [2842], 'Database': [2851], '2011;9(3):2097.': [2857], '2097,': [2858], '34': [2859], 'Eisinger': [2861], 'DA': [2862], 'Ammer': [2864], 'Epidermal': [2867], 'growth': [2868, 2884, 2889], 'switches': [2871], 'delta-opioid': [2872], 'receptor-stimulated': [2873], 'extracellular': [2874], 'signal-regulated': [2875], 'kinases': [2876], '2': [2879], 'signaling': [2880, 3118], 'epidermal': [2883], 'insulin-like': [2888], 'factor-1': [2890], 'receptor-dependent': [2891], 'mechanism.': [2892], 'Molecular': [2893], '79,': [2895], '326–': [2896], '335.': [2897], 'Jordan': [2900], 'RB,': [2901], 'BJ,': [2903], 'Arnold': [2904], 'Skelton': [2907], 'WD,': [2908], '1972.': [2909], 'Human': [2910], 'chromosomes': [2911], 'General': [2916, 3215], 'Psychiatry,': [2917], '27,': [2918, 3996], '511–': [2919], '515.': [2920], 'Farney': [2921], 'Walker': [2923], 'Cloward': [2925], 'TV': [2926], 'Rhondeau': [2928], 'Sleep-disordered': [2931], 'breathing': [2932], 'opioid': [2936], 'therapy.': [2937], 'Chest,': [2938], '123,': [2939, 3212], '632–': [2940], '639.': [2941], 'Feilberg': [2942], 'VL,': [2943], 'Rosenborg': [2944], 'Broen': [2946], 'Christensen': [2947, 3645], 'Mogensen': [2950], 'JV,': [2951], 'Excretion': [2953], 'breast': [2958], 'milk.': [2959], 'Acta': [2960], 'Anaesthesiologica': [2961], 'Scandinavica,': [2962], '33,': [2963, 3542], '426–': [2964], 'Fist': [2966], 'Byrne': [2968], 'CJ': [2969], 'Gerlach': [2971], 'WL,': [2972], 'Patent': [2976], 'Number': [2977], '6,067,749,': [2978], 'strain': [2981], 'high': [2983], 'concentration': [2984], 'oripavine,': [2988], 'May': [2989], 'Forth': [2992], 'Henschler': [2994], 'Rummel': [2996], 'U': [2999], '2001.': [3003, 3373, 3887], 'Urban': [3010], 'Fischer': [3012], 'Jena,': [3014], '8.': [3015, 3607], 'vollständig': [3016], 'überarbeitete': [3017], 'Aufl.,': [3018], 'S.': [3019], '564.': [3020], 'Frantzen': [3021], 'Bröcker': [3023], 'EB': [3024], 'Trautmann': [3026], 'Immediate-type': [3029], 'allergy': [3030], 'Allergy,': [3035], '55,': [3036], '97–': [3037], '98.': [3038], 'Frenk': [3039], 'Pro-': [3042], 'anticonvulsant': [3044], 'actions': [3045], 'endogenous': [3050], 'opioids:': [3051], 'multiple': [3056], 'non-opiate': [3059], 'systems.': [3060], 'Research,': [3062], '287,': [3063], '197–': [3064], 'Frohne': [3066, 3079], 'Pfänder': [3069, 3082], 'HJ,': [3070, 3083, 3353, 3834], '1987.': [3071, 3525], 'Giftpflanzen;': [3072, 3085], '3.': [3073, 3252], 'Verlagsgesellschaft': [3076, 3089], 'mbH': [3077, 3090], 'Stuttgart.': [3078, 3091], 'Frölich': [3092], 'Dees': [3094], 'Paetz': [3096], 'Ren': [3098], 'X,': [3099], 'Lohse': [3100], 'MJ,': [3101, 3825], 'Nikolaev': [3102], 'VO': [3103], 'Distinct': [3108], 'at': [3114], 'G(i)-protein': [3115], 'beta-arrestin': [3117], 'pathways': [3119], 'activated': [3120], 'mu-opioid': [3124], 'receptor.': [3125], '81,': [3128], '1248–': [3129], '1254.': [3130], 'Fujinaga': [3131], 'Mazze': [3134], 'RI,': [3135], 'Teratogenic': [3137], 'postnatal': [3139], 'developmental': [3140], 'studies': [3141], 'Sprague-Dawley': [3145], 'Teratology,': [3147, 3872, 4040], '38,': [3148], '401–': [3149], '410.': [3150], 'Gatehouse': [3151], 'DG,': [3152], 'Stemp': [3153], 'Pascoe': [3155], 'Wilcox': [3157], 'Hawker': [3159], 'Tweats': [3162], 'DJ,': [3163], 'Investigations': [3165], 'into': [3166], 'induction': [3168], 'aneuploidy': [3170], 'polyploidy': [3172], 'mammalian': [3174], 'cells': [3175, 3742], 'anti-tussive': [3178], 'agent': [3179], 'hydrochloride.': [3181], '6,': [3183], '279–': [3184], '283.': [3185], 'Geber': [3186], 'WF': [3187], 'Schramm': [3189], 'LC,': [3190], '1975.': [3191, 3602], 'Congenital': [3192], 'malformations': [3193, 4037], 'central': [3196], 'nervous': [3197], 'produced': [3199], 'analgesics': [3202], 'hamster.': [3205], '705–': [3213], '713.': [3214], 'Unbehend': [3217], 'Lindhauer': [3219], 'Kniel': [3221], 'Moser': [3224], 'Untersuchungen': [3227], 'Reduzierung': [3229], 'Mohngebäcken': [3235], 'praktikablen': [3237], 'technologischen': [3238], 'Massnahmen.': [3239], 'Getreidetechnologie,': [3240], '61,': [3241], '36–': [3242], '42.': [3243], 'Gessner': [3244], 'O,': [3245], 'Gift-': [3247], 'Arzneipflanzen': [3249], 'Mitteleuropa;': [3251], 'Carl': [3254], 'Winter': [3255], 'Universitätsverlag,': [3256], 'LS,': [3261], 'Rall': [3262], 'TW': [3263], 'Murad': [3265], '7th': [3273], "Gilman's.": [3278], 'MacMillan': [3279], 'Co.,': [3281], 'York,': [3283], 'Golianu': [3285], 'Krane': [3287], 'Galloway': [3289], 'KS': [3290], 'Yaster': [3292], 'Pediatric': [3295, 3299], 'management.': [3298, 3787], 'Clinics': [3300], 'North': [3302], '47,': [3304], '559–': [3305], '587.': [3306], 'Grove': [3307], 'Spencer': [3309], 'GF,': [3310], 'Wakeman': [3311], 'MV': [3312], 'Tookey': [3314], 'Agricultural': [3325], '896–': [3330], '897.': [3331], 'GW,': [3333, 3343, 3392, 3420], 'sans': [3336], 'morpheus.': [3337], 'Lancet,': [3338], '346,': [3339], '652–': [3340], '653.': [3341], 'Conno': [3344], 'Cherny': [3346], 'Hanna': [3348], 'Kalso': [3350], 'McQuay': [3352], 'Mercadante': [3354], 'Meynadier': [3356], 'Poulain': [3358], 'Ripamonti': [3360], 'Radbruch': [3362], 'Casas': [3364], 'Sawe': [3366], 'Twycross': [3368, 3393], 'RG': [3369, 3394], 'Ventafridda': [3371], 'alternative': [3376], 'cancer': [3379], 'EAPC': [3382], 'recommendations.': [3383], 'British': [3384], 'Cancer,': [3387, 3431], '587–': [3389], '593.': [3390], 'Lloyd': [3396], 'Unexpected': [3399], 'complication': [3400], 'successful': [3402], 'nerve': [3403], 'block.': [3404], 'induced': [3406], 'precipitated': [3409], 'removal': [3411], 'severe': [3413], 'Anaesthesia,': [3415], '37–': [3417], '39.': [3418], 'Controlled-release': [3422], '(MST': [3424], 'contin)': [3425], 'cancer-The': [3428], 'experience.': [3430], '63,': [3432], '2378–': [3433], '2382.': [3434], 'Sticher': [3437], 'O': [3438, 3976], 'Steinegger': [3440], 'Pharmakognosie-Phytopharmazie;': [3443], '6.': [3444], 'Hardman': [3449], 'Limbird': [3451], 'LE,': [3452], 'Molinoff': [3453], 'PB,': [3454], 'Ruddon': [3455], 'RW': [3456], 'basis': [3466], 'therapeutics.': [3468], '9th': [3469], 'McGraw-Hill.': [3471], 'Harpel': [3472], 'HS,': [3473], 'Gautieri': [3476], 'RF,': [3477], '1968.': [3478], 'Morphine-induced': [3479], 'Exencephaly': [3483], 'axial': [3485], 'skeletal': [3486], 'fusions.': [3487], '57,': [3492, 3821], '1590–': [3493], '1597.': [3494], 'Hartel': [3495], 'CR,': [3496, 3501], 'Woods': [3497], 'JH': [3498], 'Schuster': [3500], 'Behavioral': [3503], 'effects': [3504, 4018], 'rhesus': [3509], 'monkey.': [3510], 'Biochemistry': [3512], 'Behavior,': [3514], '14,': [3515], '805–': [3516], '809.': [3517], 'Hayes': [3518], 'LW,': [3519], 'Krasselt': [3520], 'WG': [3521], 'Mueggler': [3523], 'PA,': [3524], 'Concentrations': [3526], 'ingestion': [3536], 'seeds.': [3539], '806–': [3543], '808.': [3544], 'Heinonen': [3545], 'OP,': [3546], 'Slone': [3547], 'Shapiro': [3550], '1977.': [3552, 3757], 'Birth': [3553], 'Defects': [3554], 'Pregnancy.': [3558], 'Littleton,': [3559], 'Massachusetts.': [3560], 'Group.': [3563], '287–': [3564], '295.': [3565], 'Hill': [3566], 'Cairns': [3568], 'Cheng': [3570], 'CC': [3571], 'Schaffer': [3573], 'Multiple': [3576], 'aspects': [3577], 'hair': [3579], 'analysis': [3580], 'opiates:': [3582], 'methodology,': [3583], 'workplace': [3586], 'populations,': [3587], 'ingestion.': [3592], 'Analytical': [3595], '696–': [3598], '703.': [3599], 'Hoppe': [3600], 'HA,': [3601], 'Drogenkunde,': [3603], 'Band': [3604], '1,': [3605], 'Angiospermen,': [3606], 'Walter': [3609], 'Gruyter': [3611], 'Berlin.': [3613], 'Huybrechts': [3614], 'Sioen': [3616], 'Boon': [3618], 'PE,': [3619], 'Ruprich': [3620], 'Lafay': [3622], 'Turrini': [3624], 'Amiano': [3626], 'Hirvonen': [3628], 'Neve': [3631], 'Arcella': [3633], 'Moschandreas': [3635], 'Westerlund': [3637], 'Ribas-Barba': [3639], 'Hilbig': [3641], 'Papoutsou': [3643], 'Oltarzewski': [3647], 'Virtanen': [3649], 'Rehurkova': [3651], 'Azpiri': [3653], 'Sette': [3655], 'Kersting': [3657], 'Walkiewicz': [3659], 'Serra-Majem': [3661], 'Volatier': [3663], 'JL,': [3664], 'Trolle': [3665], 'Tornaritis': [3667], 'Busk': [3669], 'Kafatos': [3671], 'Fabiansson': [3673], 'Henauw': [3676], 'S': [3677], 'Klaveren': [3680], 'press.': [3683, 3703], 'Assessments': [3686], 'Children': [3688], 'Europe': [3690], '(the': [3691], 'EXPOCHI': [3692], 'project):': [3693], 'rationale,': [3694], 'methods': [3695], 'design.': [3697], 'Public': [3700], 'Health,': [3701], 'IPCS': [3704], '(International': [3705], 'Programme': [3706], 'Chemical': [3708], 'Safety),': [3709], 'Codeine.': [3711], 'www.inchem.org/documents/pims/pharm/codeine.htm.': [3714], 'Ishidate': [3715], 'Jr.,': [3717], 'Hayashi': [3718], 'Sawada': [3720], 'Matsuoka': [3722], 'Yoshikawa': [3724], 'Ono': [3726], 'Nakadate': [3729], 'test': [3733], 'medical': [3735], 'drugs-chromosome': [3736], 'aberration': [3737], 'tests': [3738], 'Chinese': [3740], 'hamster': [3741], 'vitro': [3744], "(author's": [3745], 'transl).': [3746], 'Eisei': [3747], 'Shikenjo': [3748], 'Hokoku,': [3749], '55–': [3750], '61.': [3751], 'Iwamoto': [3752], 'Klaassen': [3755], '1st-pass': [3758], 'effectt': [3759], '200,': [3770], '236–': [3771], '244.': [3772], 'Jansson': [3773], 'LM,': [3774], 'Velez': [3775], 'Harrow': [3778], 'opioid-exposed': [3782], 'newborn:': [3783], 'pharmacologic': [3786], '5,': [3792], '47–': [3793], '55.': [3794], 'Jennings': [3795], 'AL,': [3796], 'Davies': [3797], 'Higgins': [3799], 'JP,': [3800], 'Gibbs': [3801], 'JS': [3802], 'Broadley': [3804], 'KE,': [3805], 'systematic': [3808], 'Thorax,': [3820], '939–': [3822], '944.': [3823], 'McDonagh': [3826], 'TA,': [3827], 'Harkness': [3828], 'McKay': [3830], 'SE': [3831], 'Dargie': [3833], 'relief': [3839], 'breathlessness': [3841], 'heart': [3846], 'failure-a': [3847], 'pilot': [3848], 'Heart': [3853], 'Failure,': [3854], '753–': [3856], '756.': [3857], 'Jurand': 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