Hemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS) following treatment with tisagenlecleucel

Name: Work Video:
Duration: 3 min 30 s
Description: Abstract Chimeric antigen receptor (CAR) T cell–related HLH/MAS is an unusual manifestation of severe cytokine release syndrome (CRS) with poor prognosis and a challenging diagnosis. The establishment of specific diagnosis criteria is essential, and the combination of several techniques for CAR T‐cell follow‐up, allows a more precise management of this complication.
R Rojas; Ignacio Gómez‐Centurión; Rebeca Bailén; Mariana Bastos‐Oreiro; Francisco Díaz‐Crespo; Diego Carbonell; Rafael Correa‐Rocha; Marjorie Pion; Cristina Muñoz; Milagros Sancho; Isabel Fernández; Gillen Oarbeascoa; Ana Pérez‐Corral; Carolina Martínez‐Laperche; Javier Anguita; Ismael Buño; Javier Menárguez; José L. Díez‐Martin; Mi Kwon
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'is_corresponding': False, 'raw_author_name': 'Reyes Maria Martín‐Rojas', 'raw_affiliation_strings': ['Departament of Hematology Hospital General Universitario Gregorio Marañón Madrid Spain'], 'affiliations': [{'raw_affiliation_string': 'Departament of Hematology Hospital General Universitario Gregorio Marañón Madrid Spain', 'institution_ids': ['https://openalex.org/I2960094004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067861051', 'display_name': 'Ignacio Gómez‐Centurión', 'orcid': 'https://orcid.org/0000-0001-8428-700X'}, 'institutions': [{'id': 'https://openalex.org/I2960094004', 'display_name': 'Hospital General Universitario Gregorio Marañón', 'ror': 'https://ror.org/0111es613', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2960094004', 'https://openalex.org/I4210139293']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Ignacio Gómez‐Centurión', 'raw_affiliation_strings': ['Departament of 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