Title: Meiotic Arresting Substance Separated from Porcine Ovarian Granulosa Cells and Hypothetical Arresting Mechanism of Meiosis
Abstract: In mammals, oogonia enter prophase of the first meiotic division in prenatal life, and shortly after birth, all oocytes are arrested in a late prophase known as the dictyate stage, and when an oocyte in an ovary reaches the end of its growth period, it contains a single large nucleus called the germinal vesicle (Franchi et al., 1962). It is now generally accepted that the resumption of the arrested first meiotic division occurs as a result of the surge of luteinizing hormone (LH) at each ovarian cycle (Shuetz, 1969; Tsafriri, 1978a), although the ability to complete the first meiotic division is related as well to the stage of follicular development (Tsafriri and Channing, 1975a; Sorensen and Wassarman, 1976).
Publication Year: 1982
Publication Date: 1982-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 30
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