Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W37435568', 'doi': None, 'title': 'Distributions of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in Japan and their toxicities.', 'display_name': 'Distributions of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in Japan and their toxicities.', 'publication_year': 2005, 'publication_date': '2005-01-01', 'ids': {'openalex': 'https://openalex.org/W37435568', 'mag': '37435568', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16609670'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16609670', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103011643', 'display_name': 'Shoji F. Nakayama', 'orcid': 'https://orcid.org/0000-0001-7772-0389'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shoji Nakayama', 'raw_affiliation_strings': ['Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010596801', 'display_name': 'Kouji H. Harada', 'orcid': 'https://orcid.org/0000-0001-7319-123X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kouji Harada', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103389034', 'display_name': 'Kayoko Inoue', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kayoko Inoue', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103486382', 'display_name': 'Kazuaki Sasaki', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kazuaki Sasaki', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089899279', 'display_name': 'Seery Benjamin', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Benjamin Seery', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060298207', 'display_name': 'Norimitsu Saito', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Norimitsu Saito', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103018527', 'display_name': 'Akio Koizumi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Akio Koizumi', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.079, 'has_fulltext': False, 'cited_by_count': 75, 'citation_normalized_percentile': {'value': 0.928563, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '12', 'issue': '6', 'first_page': '293', 'last_page': '313'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11869', 'display_name': 'Per- and polyfluoroalkyl substances research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2304', 'display_name': 'Environmental Chemistry'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11869', 'display_name': 'Per- and polyfluoroalkyl substances research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2304', 'display_name': 'Environmental Chemistry'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10190', 'display_name': 'Air Quality and Health Impacts', 'score': 0.9812, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10122', 'display_name': 'Toxic Organic Pollutants Impact', 'score': 0.9749, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/perfluorooctanoic-acid', 'display_name': 'Perfluorooctanoic acid', 'score': 0.99444723}, {'id': 'https://openalex.org/keywords/perfluorooctane', 'display_name': 'Perfluorooctane', 'score': 0.97995484}], 'concepts': [{'id': 'https://openalex.org/C2775979320', 'wikidata': 'https://www.wikidata.org/wiki/Q418348', 'display_name': 'Perfluorooctanoic acid', 'level': 2, 'score': 0.99444723}, {'id': 'https://openalex.org/C2781314072', 'wikidata': 'https://www.wikidata.org/wiki/Q421426', 'display_name': 'Perfluorooctane', 'level': 4, 'score': 0.97995484}, {'id': 'https://openalex.org/C107872376', 'wikidata': 'https://www.wikidata.org/wiki/Q321355', 'display_name': 'Environmental chemistry', 'level': 1, 'score': 0.6525688}, {'id': 'https://openalex.org/C112570922', 'wikidata': 'https://www.wikidata.org/wiki/Q60528603', 'display_name': 'Contamination', 'level': 2, 'score': 0.52651227}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.49221388}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4746414}, {'id': 'https://openalex.org/C8625798', 'wikidata': 'https://www.wikidata.org/wiki/Q752112', 'display_name': 'Surface water', 'level': 2, 'score': 0.430214}, {'id': 'https://openalex.org/C2778894819', 'wikidata': 'https://www.wikidata.org/wiki/Q922718', 'display_name': 'Sulfonate', 'level': 3, 'score': 0.37030035}, {'id': 'https://openalex.org/C39432304', 'wikidata': 'https://www.wikidata.org/wiki/Q188847', 'display_name': 'Environmental science', 'level': 0, 'score': 0.31446612}, {'id': 'https://openalex.org/C87717796', 'wikidata': 'https://www.wikidata.org/wiki/Q146326', 'display_name': 'Environmental engineering', 'level': 1, 'score': 0.15180883}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.14524448}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.09859869}, {'id': 'https://openalex.org/C537181965', 'wikidata': 'https://www.wikidata.org/wiki/Q658', 'display_name': 'Sodium', 'level': 2, 'score': 0.0946092}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D017738', 'descriptor_name': 'Alkanesulfonic Acids', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D017738', 'descriptor_name': 'Alkanesulfonic Acids', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D002210', 'descriptor_name': 'Caprylates', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D002210', 'descriptor_name': 'Caprylates', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D005466', 'descriptor_name': 'Fluorocarbons', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D005466', 'descriptor_name': 'Fluorocarbons', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D014874', 'descriptor_name': 'Water Pollutants, Chemical', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D014874', 'descriptor_name': 'Water Pollutants, Chemical', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D017738', 'descriptor_name': 'Alkanesulfonic Acids', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D017738', 'descriptor_name': 'Alkanesulfonic Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002210', 'descriptor_name': 'Caprylates', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D002210', 'descriptor_name': 'Caprylates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015331', 'descriptor_name': 'Cohort Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005466', 'descriptor_name': 'Fluorocarbons', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D005466', 'descriptor_name': 'Fluorocarbons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007564', 'descriptor_name': 'Japan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007928', 'descriptor_name': 'Lethal Dose 50', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014874', 'descriptor_name': 'Water Pollutants, Chemical', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D014874', 'descriptor_name': 'Water Pollutants, Chemical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16609670', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 57, 'referenced_works': ['https://openalex.org/W1505273877', 'https://openalex.org/W168276155', 'https://openalex.org/W1917491239', 'https://openalex.org/W1964923030', 'https://openalex.org/W1965345679', 'https://openalex.org/W1966130148', 'https://openalex.org/W1966162583', 'https://openalex.org/W1971027475', 'https://openalex.org/W1972258539', 'https://openalex.org/W1976770880', 'https://openalex.org/W1976878552', 'https://openalex.org/W1977155984', 'https://openalex.org/W1978927533', 'https://openalex.org/W1981433415', 'https://openalex.org/W1987040388', 'https://openalex.org/W1989064042', 'https://openalex.org/W1996801451', 'https://openalex.org/W1997309359', 'https://openalex.org/W1999600038', 'https://openalex.org/W2007370532', 'https://openalex.org/W2017373987', 'https://openalex.org/W2018190812', 'https://openalex.org/W2018195888', 'https://openalex.org/W2020894239', 'https://openalex.org/W2022879961', 'https://openalex.org/W2030466622', 'https://openalex.org/W2031014117', 'https://openalex.org/W2036077109', 'https://openalex.org/W2040393913', 'https://openalex.org/W2041925174', 'https://openalex.org/W2044455946', 'https://openalex.org/W2049354575', 'https://openalex.org/W2051051975', 'https://openalex.org/W2051220320', 'https://openalex.org/W2053849036', 'https://openalex.org/W2059758444', 'https://openalex.org/W2064846151', 'https://openalex.org/W2067923517', 'https://openalex.org/W2072920431', 'https://openalex.org/W2075016249', 'https://openalex.org/W2075053859', 'https://openalex.org/W2078553897', 'https://openalex.org/W2081715527', 'https://openalex.org/W2091559200', 'https://openalex.org/W2092025136', 'https://openalex.org/W2094583299', 'https://openalex.org/W2101992164', 'https://openalex.org/W2105954461', 'https://openalex.org/W2111493612', 'https://openalex.org/W2127286660', 'https://openalex.org/W2134791901', 'https://openalex.org/W2144144303', 'https://openalex.org/W2148564390', 'https://openalex.org/W2165031389', 'https://openalex.org/W2165677144', 'https://openalex.org/W2169545575', 'https://openalex.org/W2523947619'], 'related_works': ['https://openalex.org/W3142683328', 'https://openalex.org/W2400133601', 'https://openalex.org/W2372176485', 'https://openalex.org/W2351823398', 'https://openalex.org/W2186798296', 'https://openalex.org/W2131825178', 'https://openalex.org/W2095367286', 'https://openalex.org/W2091607327', 'https://openalex.org/W1999767076', 'https://openalex.org/W1994484365'], 'abstract_inverted_index': {'Perfluorooctanoic': [0], 'acid': [1], '(PFOA)': [2], 'and': [3, 30, 62, 77, 111, 119, 127, 140, 151, 215, 247, 252], 'perfluorooctane': [4], 'sulfonate': [5], '(PFOS)': [6], 'are': [7, 70, 116, 162, 239, 256, 260], 'end': [8], 'products': [9], 'of': [10, 20, 34, 42, 55, 74, 84, 109, 125, 149, 157, 160, 166, 221], 'many': [11], 'fluorochemical': [12], 'compounds': [13], 'in': [14, 28, 65, 68, 71, 86, 93, 113, 129, 154, 178, 200, 223, 228, 235, 241, 264], 'the': [15, 32, 40, 52, 56, 72, 82, 114, 155, 158], 'natural': [16], 'environment.': [17], 'The': [18, 107, 123, 147], 'aim': [19], 'this': [21], 'review': [22], 'is': [23, 96], 'to': [24, 50, 99, 137, 143, 190, 212], 'summarize': [25], 'several': [26], 'studies': [27], 'Japan': [29, 69], 'characterize': [31], 'toxicities': [33, 234], 'these': [35], 'compounds.': [36], 'We': [37], 'also': [38], 'compared': [39], 'levels': [41, 108, 148], 'contamination': [43], 'with': [44], 'those': [45, 165], 'reported': [46], 'from': [47, 103, 133, 141], 'various': [48], 'countries': [49], 'illustrate': [51], 'unique': [53], 'situation': [54], 'toxicological': [57], 'issues': [58], 'within': [59], 'Japan.': [60], 'PFOA': [61, 91, 110, 126, 150, 214], 'PFOS': [63, 85, 112, 128, 152, 216], 'concentrations': [64, 124], 'surface': [66, 87, 94], 'water': [67, 88, 95], 'ranges': [73], '0.1-67,000': [75], 'ng/L': [76], '0.1-526': [78], 'ng/L,': [79], 'respectively.': [80, 122, 146], 'While': [81], 'origin': [83], 'remains': [89], 'unknown,': [90], 'present': [92, 153], 'very': [97], 'likely': [98], 'have': [100], 'been': [101], 'released': [102], 'a': [104, 218], 'few': [105], 'industries.': [106], 'atmosphere': [115], '71.8-919': [117], 'pg/m3': [118], '2.3-21.8': [120], 'pg/m3,': [121], 'Japanese': [130], 'serum': [131, 156], 'range': [132], 'an': [134, 176, 198, 224], 'undetectable': [135], 'level': [136], '52.2': [138], 'ng/ml': [139], '0.2': [142], '57.7': [144], 'ng/ml,': [145], 'inhabitants': [159], 'Kyoto': [161], 'higher': [163], 'than': [164], 'other': [167], 'cities.': [168], 'One': [169], 'epidemiological': [170], 'study': [171, 193, 227], 'conducted': [172, 194], 'by': [173, 195], '3M': [174, 196], 'revealed': [175, 197], 'increase': [177, 183, 199], 'prostate': [179], 'cancer': [180, 202], 'mortality': [181, 203], '[3.3-fold': [182], '(95%': [184], 'CI,': [185], '1.02-10.6)]': [186], 'among': [187, 209], 'workers': [188, 210], 'exposed': [189, 211], 'PFOA.': [191], 'Another': [192], 'bladder': [201], '(SMR': [204], '12.77,': [205], '95%': [206], 'CI': [207], '2.63-37.35)': [208], 'PFOS.': [213], 'had': [217], 'low': [219], 'order': [220], 'toxicity': [222, 226], 'acute': [225], 'rodents;': [229], 'however,': [230], 'they': [231], 'exhibited': [232], 'versatile': [233], 'primates.': [236], 'Both': [237], 'chemicals': [238], 'carcinogenic': [240], 'rodents,': [242], 'causing': [243], 'reproductive': [244], 'toxicity,': [245], 'neurotoxicity,': [246], 'hepatotoxicity.': [248], 'Additionally,': [249], 'peroxisome': [250], 'proliferation': [251], 'calcium': [253], 'channel': [254], 'modulation': [255], 'demonstrated': [257], 'effects.': [258], 'There': [259], 'large': [261], 'interspecies': [262], 'differences': [263], 'toxicokinetics.': [265]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W37435568', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-14T18:33:51.138942', 'created_date': '2016-06-24'}