Title: The therapeutic effect of Shuxuening injection on acute cerebral infarction and its mechanism
Abstract: Objective:To investigate the therapeutic effect of traditional Chinese medicine,Shuxuening injection on the treatment of acute cerebral infarction and its mechanism.Methods:Patients in the treatment group(n=60) and control group(n=58) were injected with Shuxuening injection and Danshen injection respectively.The treatment period of two group lasted 2 weeks.The clinical therapeutic effects,neurological functional deficit scores(NFDS) and Barthel index,hemorheology indexes,serum lipid,nitric oxide and endothelin had been evaluated in both groups before and after 2 weeks treatment,except Barthel index which was accessed in both groups before treatment and 4 weeks later.Results:After 2 weeks treatment,the total clinical effective rate in treatment group and control group was 88.4% and 70.7%(P0.05).NFDS,Barthel Index,hemorheology indexes,serum lipid,nitric oxide and endothelin of both groups were improved after treatment with Shuxuening injection(P0.05 or P0.01).These effects were more significant in treatment group compared with control group(P0.05 or P0.01).No side effect of Shuxuening injection was found in the trial.Conclusion:The study showed that Shuxuening injection is better than Danshen injection in the treatment of acute cerebral infarction.Shuxuening injection is able to improve patients’ life quality by decreasing patients’ NFDS and raising the Barthel index,which is related to its effect of promoting the recovery of hemorheology,serum lipid and vascular endothelium function.Shuxuening injection is an ideal herb drug for acute cerebral infarction.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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Cited By Count: 1
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