Etiology and Risk Factors for Rheumatoid Arthritis: A State-of-the-Art Review

Name: Work Video:
Duration: 3 min 30 s
Vasco C. Romão; João Eurico Fonseca
{'id': 'https://openalex.org/W3216098246', 'doi': 'https://doi.org/10.3389/fmed.2021.689698', 'title': 'Etiology and Risk Factors for Rheumatoid Arthritis: A State-of-the-Art Review', 'display_name': 'Etiology and Risk Factors for Rheumatoid Arthritis: A State-of-the-Art Review', 'publication_year': 2021, 'publication_date': '2021-11-26', 'ids': {'openalex': 'https://openalex.org/W3216098246', 'doi': 'https://doi.org/10.3389/fmed.2021.689698', 'mag': '3216098246', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34901047'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fmed.2021.689698', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fmed.2021.689698/pdf', 'source': {'id': 'https://openalex.org/S2597052008', 'display_name': 'Frontiers in Medicine', 'issn_l': '2296-858X', 'issn': ['2296-858X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fmed.2021.689698/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017617307', 'display_name': 'Vasco C. Romão', 'orcid': 'https://orcid.org/0000-0002-5603-9436'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}, {'id': 'https://openalex.org/I4210114390', 'display_name': 'Centro Hospitalar Lisboa Norte', 'ror': 'https://ror.org/020sr6z07', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114390']}, {'id': 'https://openalex.org/I4210149283', 'display_name': 'Hospital de Santa Maria', 'ror': 'https://ror.org/05bz1tw26', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210149283']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Vasco C. Romão', 'raw_affiliation_strings': ['Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET), Lisbon, Portugal', 'Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}, {'raw_affiliation_string': 'Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET), Lisbon, Portugal', 'institution_ids': ['https://openalex.org/I4210114390', 'https://openalex.org/I4210149283']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5043747371', 'display_name': 'João Eurico Fonseca', 'orcid': 'https://orcid.org/0000-0003-1432-3671'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}, {'id': 'https://openalex.org/I4210114390', 'display_name': 'Centro Hospitalar Lisboa Norte', 'ror': 'https://ror.org/020sr6z07', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114390']}, {'id': 'https://openalex.org/I4210149283', 'display_name': 'Hospital de Santa Maria', 'ror': 'https://ror.org/05bz1tw26', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210149283']}], 'countries': ['PT'], 'is_corresponding': True, 'raw_author_name': 'João Eurico Fonseca', 'raw_affiliation_strings': ['Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET), Lisbon, Portugal', 'Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}, {'raw_affiliation_string': 'Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET), Lisbon, Portugal', 'institution_ids': ['https://openalex.org/I4210114390', 'https://openalex.org/I4210149283']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5043747371'], 'corresponding_institution_ids': ['https://openalex.org/I141596103', 'https://openalex.org/I4210114390', 'https://openalex.org/I4210149283'], 'apc_list': {'value': 2490, 'currency': 'USD', 'value_usd': 2490, 'provenance': 'doaj'}, 'apc_paid': {'value': 2490, 'currency': 'USD', 'value_usd': 2490, 'provenance': 'doaj'}, 'fwci': 4.724, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 97, 'citation_normalized_percentile': {'value': 0.476013, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '8', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10200', 'display_name': 'Rheumatoid Arthritis Research and Therapies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10200', 'display_name': 'Rheumatoid Arthritis Research and Therapies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10308', 'display_name': 'Systemic Lupus Erythematosus Research', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11616', 'display_name': 'Autoimmune and Inflammatory Disorders Research', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/etiology', 'display_name': 'Etiology', 'score': 0.6988961}, {'id': 'https://openalex.org/keywords/genetic-predisposition', 'display_name': 'Genetic predisposition', 'score': 0.4291364}], 'concepts': [{'id': 'https://openalex.org/C137627325', 'wikidata': 'https://www.wikidata.org/wiki/Q156318', 'display_name': 'Etiology', 'level': 2, 'score': 0.6988961}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.64841175}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.64058733}, {'id': 'https://openalex.org/C2777575956', 'wikidata': 'https://www.wikidata.org/wiki/Q187255', 'display_name': 'Rheumatoid arthritis', 'level': 2, 'score': 0.60487837}, {'id': 'https://openalex.org/C147077947', 'wikidata': 'https://www.wikidata.org/wiki/Q1515895', 'display_name': 'Socioeconomic status', 'level': 3, 'score': 0.5236834}, {'id': 'https://openalex.org/C107130276', 'wikidata': 'https://www.wikidata.org/wiki/Q133805', 'display_name': 'Epidemiology', 'level': 2, 'score': 0.446469}, {'id': 'https://openalex.org/C50440223', 'wikidata': 'https://www.wikidata.org/wiki/Q1475848', 'display_name': 'Risk factor', 'level': 2, 'score': 0.44336742}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.42991593}, {'id': 'https://openalex.org/C67636389', 'wikidata': 'https://www.wikidata.org/wiki/Q784237', 'display_name': 'Genetic predisposition', 'level': 3, 'score': 0.4291364}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.40156153}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.3510616}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.16177765}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.14897326}], 'mesh': [], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fmed.2021.689698', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fmed.2021.689698/pdf', 'source': {'id': 'https://openalex.org/S2597052008', 'display_name': 'Frontiers in Medicine', 'issn_l': '2296-858X', 'issn': ['2296-858X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/dd86e1e5563e4409b68f1ac10e9a9bd3', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10451/50413', 'pdf_url': 'https://repositorio.ul.pt/bitstream/10451/50413/1/Etiology_risk.pdf', 'source': {'id': 'https://openalex.org/S4306401074', 'display_name': 'Repositório da Universidade de Lisboa (University of Lisbon)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I141596103', 'host_organization_name': 'University of Lisbon', 'host_organization_lineage': ['https://openalex.org/I141596103'], 'host_organization_lineage_names': ['University of Lisbon'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661097', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34901047', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fmed.2021.689698', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fmed.2021.689698/pdf', 'source': {'id': 'https://openalex.org/S2597052008', 'display_name': 'Frontiers in Medicine', 'issn_l': '2296-858X', 'issn': ['2296-858X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.86}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 317, 'referenced_works': ['https://openalex.org/W1088236639', 'https://openalex.org/W1137513493', 'https://openalex.org/W1247177501', 'https://openalex.org/W130009726', 'https://openalex.org/W136473298', 'https://openalex.org/W1493134746', 'https://openalex.org/W15033572', 'https://openalex.org/W1582344203', 'https://openalex.org/W1588400717', 'https://openalex.org/W1620983111', 'https://openalex.org/W1626677331', 'https://openalex.org/W1680529401', 'https://openalex.org/W1718876362', 'https://openalex.org/W1769185017', 'https://openalex.org/W1852206426', 'https://openalex.org/W1872612762', 'https://openalex.org/W1898729462', 'https://openalex.org/W1925647577', 'https://openalex.org/W1925892179', 'https://openalex.org/W1933626256', 'https://openalex.org/W1941546511', 'https://openalex.org/W1943338444', 'https://openalex.org/W1950484528', 'https://openalex.org/W1963726850', 'https://openalex.org/W1964890547', 'https://openalex.org/W1967596836', 'https://openalex.org/W1969015613', 'https://openalex.org/W1971108601', 'https://openalex.org/W1972616962', 'https://openalex.org/W1973652618', 'https://openalex.org/W1975829694', 'https://openalex.org/W1978827202', 'https://openalex.org/W1982106445', 'https://openalex.org/W1983142005', 'https://openalex.org/W1985360484', 'https://openalex.org/W1985372653', 'https://openalex.org/W1985567929', 'https://openalex.org/W1986653615', 'https://openalex.org/W1988094624', 'https://openalex.org/W1988148616', 'https://openalex.org/W1988356259', 'https://openalex.org/W1989590412', 'https://openalex.org/W1990509922', 'https://openalex.org/W1995871572', 'https://openalex.org/W1996220958', 'https://openalex.org/W1996575556', 'https://openalex.org/W1996611544', 'https://openalex.org/W1999850359', 'https://openalex.org/W2001069355', 'https://openalex.org/W2002894389', 'https://openalex.org/W2003214210', 'https://openalex.org/W2006547485', 'https://openalex.org/W2006724319', 'https://openalex.org/W2007205421', 'https://openalex.org/W2007335181', 'https://openalex.org/W2007786715', 'https://openalex.org/W2010921938', 'https://openalex.org/W2011768190', 'https://openalex.org/W2015690685', 'https://openalex.org/W2015865604', 'https://openalex.org/W2016370312', 'https://openalex.org/W2017023636', 'https://openalex.org/W2017161033', 'https://openalex.org/W2017290170', 'https://openalex.org/W2017864770', 'https://openalex.org/W2018416312', 'https://openalex.org/W2019427304', 'https://openalex.org/W2022809525', 'https://openalex.org/W2023073368', 'https://openalex.org/W2024418686', 'https://openalex.org/W2024613115', 'https://openalex.org/W2025408360', 'https://openalex.org/W2027874148', 'https://openalex.org/W2028934624', 'https://openalex.org/W2029424880', 'https://openalex.org/W2033176002', 'https://openalex.org/W2035036601', 'https://openalex.org/W2036239608', 'https://openalex.org/W2037122953', 'https://openalex.org/W2041346123', 'https://openalex.org/W2043250238', 'https://openalex.org/W2047459553', 'https://openalex.org/W2049219670', 'https://openalex.org/W2050833972', 'https://openalex.org/W2051715499', 'https://openalex.org/W2052399844', 'https://openalex.org/W2055514573', 'https://openalex.org/W2056198580', 'https://openalex.org/W2056406633', 'https://openalex.org/W2057144796', 'https://openalex.org/W2057827220', 'https://openalex.org/W2058673825', 'https://openalex.org/W2059695215', 'https://openalex.org/W2060340573', 'https://openalex.org/W2061682029', 'https://openalex.org/W2064252013', 'https://openalex.org/W2064825509', 'https://openalex.org/W2066992284', 'https://openalex.org/W2067645583', 'https://openalex.org/W2068738555', 'https://openalex.org/W2070890108', 'https://openalex.org/W2073883254', 'https://openalex.org/W2074821083', 'https://openalex.org/W2074854789', 'https://openalex.org/W2078127406', 'https://openalex.org/W2079684570', 'https://openalex.org/W2083679819', 'https://openalex.org/W2084707696', 'https://openalex.org/W2085096810', 'https://openalex.org/W2086755979', 'https://openalex.org/W2088275441', 'https://openalex.org/W2090131412', 'https://openalex.org/W2092639932', 'https://openalex.org/W2093120748', 'https://openalex.org/W2094219066', 'https://openalex.org/W2095138905', 'https://openalex.org/W2097145477', 'https://openalex.org/W2100059339', 'https://openalex.org/W2100669634', 'https://openalex.org/W2102746921', 'https://openalex.org/W2103009450', 'https://openalex.org/W2103089222', 'https://openalex.org/W2103187999', 'https://openalex.org/W2103734979', 'https://openalex.org/W2104016028', 'https://openalex.org/W2104451222', 'https://openalex.org/W2104823342', 'https://openalex.org/W2105074601', 'https://openalex.org/W2105422073', 'https://openalex.org/W2105487636', 'https://openalex.org/W2106510831', 'https://openalex.org/W2109349820', 'https://openalex.org/W2109827531', 'https://openalex.org/W2112568653', 'https://openalex.org/W2113552312', 'https://openalex.org/W2115783720', 'https://openalex.org/W2116026008', 'https://openalex.org/W2116306551', 'https://openalex.org/W2118561577', 'https://openalex.org/W2119443108', 'https://openalex.org/W2120229753', 'https://openalex.org/W2120273042', 'https://openalex.org/W2121745249', 'https://openalex.org/W2122333606', 'https://openalex.org/W2124354788', 'https://openalex.org/W2124613361', 'https://openalex.org/W2124972291', 'https://openalex.org/W2127534935', 'https://openalex.org/W2128338782', 'https://openalex.org/W2128450147', 'https://openalex.org/W2129536968', 'https://openalex.org/W2130025583', 'https://openalex.org/W2130979463', 'https://openalex.org/W2130979746', 'https://openalex.org/W2131131455', 'https://openalex.org/W2132402446', 'https://openalex.org/W2132576596', 'https://openalex.org/W2133480655', 'https://openalex.org/W2136086343', 'https://openalex.org/W2136131602', 'https://openalex.org/W2136843437', 'https://openalex.org/W2136967594', 'https://openalex.org/W2137027434', 'https://openalex.org/W2137038104', 'https://openalex.org/W2137659055', 'https://openalex.org/W2139710449', 'https://openalex.org/W2139825658', 'https://openalex.org/W2140764717', 'https://openalex.org/W2141561944', 'https://openalex.org/W2141609697', 'https://openalex.org/W2141783531', 'https://openalex.org/W2142845896', 'https://openalex.org/W2144998981', 'https://openalex.org/W2145067857', 'https://openalex.org/W2145769362', 'https://openalex.org/W2146000946', 'https://openalex.org/W2146293362', 'https://openalex.org/W2146707828', 'https://openalex.org/W2146831240', 'https://openalex.org/W2147317986', 'https://openalex.org/W2147855010', 'https://openalex.org/W2147914485', 'https://openalex.org/W2149358566', 'https://openalex.org/W2151283377', 'https://openalex.org/W2153956738', 'https://openalex.org/W2153968413', 'https://openalex.org/W2154938441', 'https://openalex.org/W2156070134', 'https://openalex.org/W2156086707', 'https://openalex.org/W2157724767', 'https://openalex.org/W2159203244', 'https://openalex.org/W2160806981', 'https://openalex.org/W2161826146', 'https://openalex.org/W2162255425', 'https://openalex.org/W2162276444', 'https://openalex.org/W2163957506', 'https://openalex.org/W2165769226', 'https://openalex.org/W2168781986', 'https://openalex.org/W2168799367', 'https://openalex.org/W2169364567', 'https://openalex.org/W2169448344', 'https://openalex.org/W2169741728', 'https://openalex.org/W2170801195', 'https://openalex.org/W2170812501', 'https://openalex.org/W2176892365', 'https://openalex.org/W2232978449', 'https://openalex.org/W2234891921', 'https://openalex.org/W2253136827', 'https://openalex.org/W2253944261', 'https://openalex.org/W2254386566', 'https://openalex.org/W2287283884', 'https://openalex.org/W2290627980', 'https://openalex.org/W2297547064', 'https://openalex.org/W2304537231', 'https://openalex.org/W2325677848', 'https://openalex.org/W2325741355', 'https://openalex.org/W2341834041', 'https://openalex.org/W2395644225', 'https://openalex.org/W2400747372', 'https://openalex.org/W2415440360', 'https://openalex.org/W2415793789', 'https://openalex.org/W2417283976', 'https://openalex.org/W2461427666', 'https://openalex.org/W2470370465', 'https://openalex.org/W2471293010', 'https://openalex.org/W2480943615', 'https://openalex.org/W2495574559', 'https://openalex.org/W2510873852', 'https://openalex.org/W2516363365', 'https://openalex.org/W2526695386', 'https://openalex.org/W2530386703', 'https://openalex.org/W2533973740', 'https://openalex.org/W2535927459', 'https://openalex.org/W2544771346', 'https://openalex.org/W2552118514', 'https://openalex.org/W2554128311', 'https://openalex.org/W2559098281', 'https://openalex.org/W2560381583', 'https://openalex.org/W2562800512', 'https://openalex.org/W2578130861', 'https://openalex.org/W2583073547', 'https://openalex.org/W2586257347', 'https://openalex.org/W2591036139', 'https://openalex.org/W2599500360', 'https://openalex.org/W2599984149', 'https://openalex.org/W2604105441', 'https://openalex.org/W2605576483', 'https://openalex.org/W2607702283', 'https://openalex.org/W2738808973', 'https://openalex.org/W2742907331', 'https://openalex.org/W2744470205', 'https://openalex.org/W2745725076', 'https://openalex.org/W2746663222', 'https://openalex.org/W2750247539', 'https://openalex.org/W2751327994', 'https://openalex.org/W2755128402', 'https://openalex.org/W2756994732', 'https://openalex.org/W2758506768', 'https://openalex.org/W2761067865', 'https://openalex.org/W2762182295', 'https://openalex.org/W2768018334', 'https://openalex.org/W2779742302', 'https://openalex.org/W2783843471', 'https://openalex.org/W2786666585', 'https://openalex.org/W2786699893', 'https://openalex.org/W2788814173', 'https://openalex.org/W2789921466', 'https://openalex.org/W2791981773', 'https://openalex.org/W2800033387', 'https://openalex.org/W2800313065', 'https://openalex.org/W2803910286', 'https://openalex.org/W2804716665', 'https://openalex.org/W2806188993', 'https://openalex.org/W2806824484', 'https://openalex.org/W2808147913', 'https://openalex.org/W2810929521', 'https://openalex.org/W2814803529', 'https://openalex.org/W2885879125', 'https://openalex.org/W2887395891', 'https://openalex.org/W2887806116', 'https://openalex.org/W2897450516', 'https://openalex.org/W2898717768', 'https://openalex.org/W2903122430', 'https://openalex.org/W2904198979', 'https://openalex.org/W2904326582', 'https://openalex.org/W2912148503', 'https://openalex.org/W2913394409', 'https://openalex.org/W2913429571', 'https://openalex.org/W2914790177', 'https://openalex.org/W2914989354', 'https://openalex.org/W2915074739', 'https://openalex.org/W2915075408', 'https://openalex.org/W2919906155', 'https://openalex.org/W2935408264', 'https://openalex.org/W2951753173', 'https://openalex.org/W2951966382', 'https://openalex.org/W2958436323', 'https://openalex.org/W2969936156', 'https://openalex.org/W2972459077', 'https://openalex.org/W2981515298', 'https://openalex.org/W2989973296', 'https://openalex.org/W3009823739', 'https://openalex.org/W3011344727', 'https://openalex.org/W3012240231', 'https://openalex.org/W3037169575', 'https://openalex.org/W3039396378', 'https://openalex.org/W3042546096', 'https://openalex.org/W3049638497', 'https://openalex.org/W3049734205', 'https://openalex.org/W3080622028', 'https://openalex.org/W3086694282', 'https://openalex.org/W3090962484', 'https://openalex.org/W3195683118', 'https://openalex.org/W4211054359', 'https://openalex.org/W4247674417', 'https://openalex.org/W4298340585', 'https://openalex.org/W52089534'], 'related_works': ['https://openalex.org/W609638663', 'https://openalex.org/W4323530626', 'https://openalex.org/W4255938420', 'https://openalex.org/W354738834', 'https://openalex.org/W2890923131', 'https://openalex.org/W2309610076', 'https://openalex.org/W2047901857', 'https://openalex.org/W2019481302', 'https://openalex.org/W2016390559', 'https://openalex.org/W13949714'], 'abstract_inverted_index': {'Rheumatoid': [0], 'arthritis': [1], '(RA)': [2], 'is': [3, 12, 64, 67], 'the': [4, 18, 34, 43, 49, 61, 80, 93, 136, 146, 156], 'most': [5], 'common': [6], 'systemic': [7], 'inflammatory': [8], 'rheumatic': [9], 'disease.': [10], 'It': [11], 'associated': [13, 98], 'with': [14, 48, 99], 'significant': [15], 'burden': [16], 'at': [17, 141], 'patient': [19], 'and': [20, 51, 76, 87, 110, 112, 123, 128, 132, 143, 174], 'societal': [21], 'level.': [22], 'Extensive': [23], 'efforts': [24], 'have': [25, 40, 96, 167], 'been': [26, 97], 'devoted': [27], 'to': [28, 92], 'identifying': [29], 'a': [30, 56, 68, 152], 'potential': [31], 'cause': [32], 'for': [33], 'development': [35, 101], 'of': [36, 45, 53, 83, 148, 155, 171], 'RA.': [37, 54], 'Epidemiological': [38], 'studies': [39], 'thoroughly': [41], 'investigated': [42], 'association': [44], 'several': [46], 'factors': [47, 78, 90, 120], 'risk': [50, 82, 119, 173], 'course': [52], 'Although': [55], 'precise': [57], 'etiology': [58], 'remains': [59], 'elusive,': [60], 'current': [62, 157], 'understanding': [63], 'that': [65, 95, 166], 'RA': [66, 100], 'multifactorial': [69], 'disease,': [70], 'wherein': [71], 'complex': [72], 'interactions': [73], 'between': [74], 'host': [75, 94, 114], 'environmental': [77, 118], 'determine': [79], 'overall': [81], 'disease': [84, 172], 'susceptibility,': [85], 'persistence': [86], 'severity.': [88], 'Risk': [89], 'related': [91], 'may': [102], 'be': [103], 'divided': [104], 'into': [105], 'genetic;': [106], 'epigenetic;': [107], 'hormonal,': [108], 'reproductive': [109], 'neuroendocrine;': [111], 'comorbid': [113], 'factors.': [115, 134], 'In': [116, 135], 'turn,': [117], 'include': [121], 'smoking': [122], 'other': [124], 'airborne': [125], 'exposures;': [126], 'microbiota': [127], 'infectious': [129], 'agents;': [130], 'diet;': [131], 'socioeconomic': [133], 'present': [137], 'narrative': [138], 'review,': [139], 'aimed': [140], 'clinicians': [142], 'researchers': [144], 'in': [145], 'field': [147], 'RA,': [149], 'we': [150], 'provide': [151], 'state-of-the-art': [153], 'overview': [154], 'knowledge': [158], 'on': [159, 163], 'this': [160], 'topic,': [161], 'focusing': [162], 'recent': [164], 'progresses': [165], 'improved': [168], 'our': [169], 'comprehension': [170], 'development.': [175]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3216098246', 'counts_by_year': [{'year': 2024, 'cited_by_count': 44}, {'year': 2023, 'cited_by_count': 31}, {'year': 2022, 'cited_by_count': 22}], 'updated_date': '2025-01-04T23:18:10.131261', 'created_date': '2021-12-06'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
