Publication Information

{'id': 'https://openalex.org/W3214036360', 'doi': None, 'title': 'Dictyostelium als Wirtsmodell und Funktionsanalyse des Virulenzfaktors Mip aus Legionella pneumophila', 'display_name': 'Dictyostelium als Wirtsmodell und Funktionsanalyse des Virulenzfaktors Mip aus Legionella pneumophila', 'publication_year': 2004, 'publication_date': '2004-01-01', 'ids': {'openalex': 'https://openalex.org/W3214036360', 'mag': '3214036360'}, 'language': 'de', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://opus.bibliothek.uni-wuerzburg.de/files/1064/Dissertation.pdf', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5006572600', 'display_name': 'Carina Wagner', 'orcid': 'https://orcid.org/0000-0002-0146-702X'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Carina Wagner', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5006572600'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 61}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11916', 'display_name': 'Legionella and Acanthamoeba research', 'score': 0.9999, 'subfield': {'id': 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0.54002976}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36281332}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1742062}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.06640357}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://opus.bibliothek.uni-wuerzburg.de/files/1064/Dissertation.pdf', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': [], 'abstract_inverted_index': {'Legionella': [0, 454, 496], 'pneumophila': [1, 96, 114, 151, 269, 309], 'wurde': [2, 83, 241, 364], 'erstmals': [3], '1977': [4], 'beschrieben,': [5], 'nachdem': [6], 'der': [7, 16, 56, 289, 368, 384, 429, 459, 509, 522, 529, 560], 'Erreger': [8], 'aus': [9, 32, 448, 500, 533], 'dem': [10], 'Lungengewebe': [11], 'eines': [12, 70], 'Patienten': [13], 'isoliert': [14], 'wurde,': [15], 'an': [17, 471, 479], 'einer': [18, 53, 110, 305, 332], 'schweren': [19], 'atypischen': [20], 'Pneumonie': [21], 'erkrankt': [22], 'war.': [23], 'Das': [24, 451], 'Bakterium': [25], 'zeichnet': [26], 'sich': [27, 35, 234, 345], 'durch': [28, 94, 497, 511], 'ein': [29, 125], 'duales': [30], 'Wirtssystem': [31], 'und': [33, 103, 179, 207, 270, 286, 313, 350, 403, 466], 'kann': [34, 470], 'sowohl': [36, 417], 'in': [37, 41, 89, 141, 144, 213, 242, 273, 288, 352, 387, 418, 434, 456, 528], 'Protozoen': [38], 'als': [39, 420], 'auch': [40, 421], 'humanen': [42], 'Zellen': [43], 'vermehren.': [44], 'Ein': [45, 438], 'Ziel': [46, 440], 'dieser': [47, 243, 441], 'Arbeit': [48, 244, 442], 'war': [49, 443], 'es,': [50], 'wichtige': [51], 'Faktoren': [52], 'Legionelleninfektion': [54], 'seitens': [55], 'Wirtszelle': [57], 'zu': [58, 291, 538], 'betrachten.': [59], 'Als': [60], 'Wirtsmodell': [61], 'diente': [62], 'die': [63, 84, 105, 140, 180, 197, 257, 265, 310, 329, 346, 365, 400, 444, 457, 472, 493, 531], 'soziale': [64], 'Amobe': [65], 'Dictyostelium': [66, 77], 'discoideum.': [67, 163], 'Mit': [68, 183, 357, 483, 540], 'Hilfe': [69, 184, 358, 484, 541], 'von': [71, 86, 112, 161, 170, 185, 247, 267, 284, 359, 393, 409, 453, 475, 485, 495, 542], 'Patrick': [72], 'Farbrother': [73], '(Universitat': [74], 'Koln)': [75], 'etablierten': [76], 'DNA-Microarrays': [78], 'mit': [79, 106, 149, 295, 307, 334, 535, 544], '5906': [80], 'genspezifischen': [81], 'Sonden,': [82], 'Genexpression': [85], 'D.': [87, 142, 162, 248, 353, 388], 'discoideum': [88, 143, 249, 354, 389], 'Reaktion': [90, 145], 'auf': [91, 146], 'eine': [92, 121, 147, 191, 274, 281, 381, 498], 'Infektion': [93, 148, 306, 333], 'L.': [95, 107, 113, 150, 268, 308, 449], 'untersucht.': [97, 251], 'Zur': [98], 'Kontrolle': [99], 'dienten': [100], 'uninfizierte': [101], 'Zellen,': [102, 104], 'hackeliae': [108], 'bzw.': [109, 124, 513, 562], 'dotA-Mutante': [111], 'koinkubiert': [115], 'wurden.': [116], 'Diese': [117], 'beiden': [118], 'Stamme': [119, 401], 'weisen': [120], 'verminderte': [122], 'Pathogenitat': [123], 'deletiertes': [126], 'Pathogenitatsgen': [127], 'auf.': [128], 'Fur': [129], 'den': [130], 'Zeitpunkt': [131, 375], '24': [132], 'h': [133, 317, 372, 377], 'nach': [134, 315, 378, 507, 520], 'Infektionsbeginn': [135], 'wurden': [136], '140': [137], 'Gene': [138, 156, 221], 'gefunden,': [139], 'differentiell': [152], 'exprimiert': [153], 'werden.': [154, 194, 391, 426, 516], 'Einige': [155], 'codieren': [157], 'bereits': [158, 314], 'bekannte': [159], 'Proteine': [160, 237], 'Dazu': [164], 'gehoren': [165], 'das': [166, 245, 480], 'RtoA': [167], '(ratioA,': [168], 'Fusion': [169], 'Vesikeln),': [171], 'Discoidin': [172], 'I,': [173], 'CotB': [174], '(spore': [175], 'coat': [176], 'Protein': [177], 'SP70)': [178], 'lysosomale': [181], 'α-Mannosidase.': [182], 'Homologie-Suchen': [186], 'konnte': [187, 216, 261, 300, 341, 380, 396, 416, 487, 506, 548], 'weiteren': [188], 'unbekannten': [189], 'Proteinen': [190], 'Funktion': [192], 'zugeteilt': [193], 'Hierzu': [195], 'zahlen': [196], 'Chaperone': [198], 'ClpB': [199], '(heat': [200], 'shock': [201], 'protein': [202], 'Hsp104),': [203], 'β’-COP': [204], '(coat': [205], 'protein)': [206], 'drei': [208, 385], 'calciumbindende': [209], 'Proteine.': [210], 'Nach': [211, 558], 'Einteilung': [212], 'funktionelle': [214], 'Kategorien,': [215], 'gezeigt': [217, 301, 397, 549], 'werden,': [218, 223, 263, 302, 343, 398, 489, 550], 'dass': [219, 264, 303, 344, 399, 490, 551], 'viele': [220], 'reguliert': [222], 'deren': [224], 'Produkte': [225], 'am': [226], 'Aminosaure-Metabolismus': [227], 'beteiligt': [228], 'sind': [229], 'oder': [230], 'bei': [231], 'denen': [232], 'es': [233], 'um': [235], 'ribosomale': [236], 'handelt.': [238], 'Des': [239], 'Weiteren': [240], 'Nramp-Protein': [246], 'naher': [250], 'Nramp': [252], 'transportiert': [253], 'zweiwertige': [254], 'Kationen': [255], 'uber': [256, 370], 'phagosomale': [258], 'Membran.': [259], 'Es': [260, 461], 'festgestellt': [262, 390, 488], 'Aufnahme': [266], 'M.': [271, 335], 'avium': [272, 336], 'nramp-Mutante': [275], 'deutlich': [276], 'reduziert': [277], 'ist.': [278, 324, 503], 'Allerdings': [279], 'ist': [280], 'vermehrte': [282], 'Replikation': [283], 'Legionellen': [285, 519, 553, 566], 'Mykobakterien': [287], 'Wirtsmutante': [290], 'beobachten.': [292], 'In': [293, 339], 'Zusammenarbeit': [294], 'Salvatore': [296], 'Bozzaro': [297], '(Turin,': [298], 'Italien)': [299], 'wahrend': [304, 331], 'nramp-Expression': [311, 330], 'sinkt': [312], '48': [316, 371, 376], 'annahernd': [318], 'keine': [319], 'nramp-RNA': [320], 'im': [321, 405, 423, 524], 'Northern-Blot': [322], 'nachweisbar': [323], 'Im': [325], 'Gegensatz': [326], 'dazu': [327], 'bleibt': [328], 'relativ': [337], 'konstant.': [338], 'Infektionsstudien': [340], 'nachgewiesen': [342, 425], 'Endozytobionten': [347, 386, 430], 'TUME1,': [348], 'UWE25': [349, 404], 'UWC6': [351, 415], 'vermehren': [355], 'konnen.': [356, 557], 'spezifischen': [360], 'Cy3-markierten': [361], '16S-rRNA': [362], 'Sonden': [363], 'intrazellulare': [366], 'Zunahme': [367], 'Bakterien': [369], 'beobachtet.': [373], 'Zum': [374], 'Inokulation': [379], 'erhohte': [382], 'Anzahl': [383], 'Anhand': [392], 'elektronenmikro-skopischen': [394], 'Aufnahmen': [395], 'TUME1': [402], 'Zytoplasma': [406, 424], 'des': [407, 446], 'Wirtes': [408], 'membranosen': [410], 'Strukturen': [411], 'eng': [412], 'umschlossen': [413], 'sind.': [414], 'Vakuolen': [419], 'frei': [422], 'Die': [427, 504], 'Lokalisierung': [428, 433], 'entspricht': 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'Epithelzellen': [534], 'extrazellularer': [536, 546], 'durchwandern.': [539], 'Degradationsassays': [543], 'S35-markierter': [545], 'mip-positive': [552, 565], 'degradieren': [556], 'Serinproteaseaktivitat': [563], 'konnten': [564], 'degradieren.': [571]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3214036360', 'counts_by_year': [], 'updated_date': '2024-12-07T10:07:51.213655', 'created_date': '2021-11-22'}