Title: Structural connectomics: Where we are and where we should be?
Abstract: The chapter provides a comprehensive insight into structural connectomics, the study of brain connectivity using diffusion MRI based maps. It commences with the basics of connectome creation—parcellation, tractography and connectivity modeling, and covers the spectrum of associated problems like consistency and harmonization across scanners. Various measures derived from connectomes are comprehensively described—topological (local and global), as well as those that characterize network rewiring in the brain. Finally, the chapter presents various examples of connectomic analyses, through studies on sex differences, traumatic brain injury, brain tumors, and developmental disorders. These highlight the different types of hypotheses that can be interrogated using connectomes. The chapter concludes with a perspective on future breakthroughs that are possible with connectomes.
Publication Year: 2021
Publication Date: 2021-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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