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44, 226], 'mg': [36, 227, 235], 'for': [38, 64, 96, 103, 112, 317, 335], '7': [39], 'days': [40], 'was': [41, 72], 'followed': [42], 'by': [43], 'monthly': [45, 230], '(once': [46], 'every': [47], 'four': [48], 'weeks)': [49], 'intramuscular': [50], '(IM)': [51], 'doses': [52], 'ISM': [55, 117, 150, 233, 259, 292], '100': [56, 234], 'mg.': [57], 'Mean': [58], 'concentration': [60, 132, 190, 199], 'versus': [61, 100, 115], 'time': [62, 101, 302], 'profiles': [63, 102], 'risperidone,': [65, 67, 332], '9-OH': [66], 'active': [70, 105, 146, 309], 'moiety': [71, 106, 147, 310], 'characterized.': [73], 'Results:': [74], 'A': [75], 'total': [76], '104': [78], 'subjects': [79, 245], 'were': [80, 83, 173, 202, 236], 'enrolled,': [81], '81': [82], 'included': [84], 'safety': [87], 'population': [88], '58': [90], 'completed': [91], 'study.': [93], 'Intersubject': [94], 'variability': [95, 110], 'concentrations': [99, 142], 'presented': [107], 'a': [108], 'greater': [109], 'range': [111], '(%': [118], 'coefficient': [119], 'variation': [121], '[CV]': [122], 'range:': [123], '40–': [124], '65%': [125], '38–': [127], '52%,': [128], 'respectively).': [129, 220], 'Minimum': [130], 'plasma': [131, 141, 189, 198], 'at': [133, 191, 271], '(C': [135, 193, 200], 'min,': [136], 'ss)': [137, 195], 'fluctuation': [139], '(Fluc)': [143], 'after': [148, 274, 281], 'met': [152], 'bioequivalence': [153], 'criteria': [154], 'compared': [155], 'to': [156, 268, 290], 'reference': [158], '(geometric': [161], 'mean': [162], 'ratio': [163], '[GMR]': [164], '=': [165, 209], '1.09': [166], '0.96,': [168], 'respectively;': [169], 'both': [170], '90%': [171], 'CIs': [172], 'within': [174], '0.80–': [175], '1.25).': [176], 'Area': [177], 'under': [178], 'curve': [180], 'during': [181], 'dosing': [183], 'interval': [184], '(AUC': [185], 'tau)': [186], ',': [187], 'maximum': [188], 'max,': [194], 'average': [197], 'ave)': [201], 'only': [203], 'slightly': [204], 'higher': [205], '(GMR': [206], '[90%': [207], 'CI]': [208], '1.25': [210, 217], '[1.16–': [211, 218], '1.34],': [212, 219], '1.17': [213], '[1.08–': [214], '1.27],': [215], 'Overall,': [221], 'IM': [231], 'generally': [237], 'safe': [238], 'well': [240], 'tolerated': [241], 'participating': [244], 'with': [246, 250, 300], 'schizophrenia': [247, 298, 333], 'previously': [248], 'risperidone.': [252], 'Conclusion:': [253], 'The': [254], 'rapid': [255], 'release': [256], 'allows': [260], 'achievement': [262], 'desired': [265], 'levels': [266, 306], 'similar': [267], 'those': [269], 'observed': [270], 'Therefore,': [278], 'direct': [279], 'switch': [280], '24': [282], 'hours': [283], 'from': [284], 'last': [286], 'dose': [289], 'treatment': [293, 312], 'can': [294], 'be': [295], 'done': [296], 'no': [301], 'lag,': [303], 'maintaining': [304], 'throughout': [311], 'without': [314], 'need': [316], 'supplementation': [320], 'or': [321], 'loading': [322], 'doses.': [323], 'Keywords:': [324], 'bioequivalence,': [325], 'bioavailability,': [327], 'long-acting': [328], 'injectables,': [329], 'LAIs,': [330], 'pharmacokinetic,': [331], 'Corrigendum': [334], 'this': [336], 'paper': [337], 'has': [338], 'been': [339], 'published': [340]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3207213207', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-12-17T09:33:08.075768', 'created_date': '2021-10-25'}