Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3199041259', 'doi': 'https://doi.org/10.3390/cells10092491', 'title': 'Secreted Frizzled-Related Protein 1 Promotes Odontoblastic Differentiation and Reparative Dentin Formation in Dental Pulp Cells', 'display_name': 'Secreted Frizzled-Related Protein 1 Promotes Odontoblastic Differentiation and Reparative Dentin Formation in Dental Pulp Cells', 'publication_year': 2021, 'publication_date': '2021-09-21', 'ids': {'openalex': 'https://openalex.org/W3199041259', 'doi': 'https://doi.org/10.3390/cells10092491', 'mag': '3199041259', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34572140', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8468928'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/cells10092491', 'pdf_url': 'https://www.mdpi.com/2073-4409/10/9/2491/pdf?version=1632195586', 'source': {'id': 'https://openalex.org/S2736626452', 'display_name': 'Cells', 'issn_l': '2073-4409', 'issn': ['2073-4409'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/2073-4409/10/9/2491/pdf?version=1632195586', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5090551628', 'display_name': 'Keita Ipposhi', 'orcid': 'https://orcid.org/0000-0003-0354-695X'}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Keita Ipposhi', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010768298', 'display_name': 'Atsushi Tomokiyo', 'orcid': 'https://orcid.org/0000-0002-1638-4008'}, 'institutions': [{'id': 'https://openalex.org/I4210097767', 'display_name': 'Kyushu University Hospital', 'ror': 'https://ror.org/00ex2fc97', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I135598925', 'https://openalex.org/I4210097767']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Atsushi Tomokiyo', 'raw_affiliation_strings': ['Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I4210097767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059349757', 'display_name': 'Taiga Ono', 'orcid': 'https://orcid.org/0000-0002-7925-0883'}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Taiga Ono', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064847080', 'display_name': 'Kozue Yamashita', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kozue Yamashita', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068476151', 'display_name': 'M. Anas Alhasan', 'orcid': 'https://orcid.org/0000-0002-7228-2778'}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Muhammad Anas Alhasan', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004517343', 'display_name': 'Daigaku Hasegawa', 'orcid': 'https://orcid.org/0000-0002-2593-5633'}, 'institutions': [{'id': 'https://openalex.org/I4210097767', 'display_name': 'Kyushu University Hospital', 'ror': 'https://ror.org/00ex2fc97', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I135598925', 'https://openalex.org/I4210097767']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Daigaku Hasegawa', 'raw_affiliation_strings': ['Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I4210097767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036482353', 'display_name': 'Sayuri Hamano', 'orcid': 'https://orcid.org/0000-0003-0216-2102'}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Sayuri Hamano', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'OBT Center, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}, {'raw_affiliation_string': 'OBT Center, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077815005', 'display_name': 'Shinichiro Yoshida', 'orcid': 'https://orcid.org/0000-0003-0016-7444'}, 'institutions': [{'id': 'https://openalex.org/I4210097767', 'display_name': 'Kyushu University Hospital', 'ror': 'https://ror.org/00ex2fc97', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I135598925', 'https://openalex.org/I4210097767']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shinichiro Yoshida', 'raw_affiliation_strings': ['Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I4210097767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022869302', 'display_name': 'Hideki Sugii', 'orcid': 'https://orcid.org/0000-0002-8790-7208'}, 'institutions': [{'id': 'https://openalex.org/I4210097767', 'display_name': 'Kyushu University Hospital', 'ror': 'https://ror.org/00ex2fc97', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I135598925', 'https://openalex.org/I4210097767']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hideki Sugii', 'raw_affiliation_strings': ['Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I4210097767']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086233535', 'display_name': 'Tomohiro Itoyama', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomohiro Itoyama', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102198502', 'display_name': 'Marina Ogawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Marina Ogawa', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5062326422', 'display_name': 'Hidefumi Maeda', 'orcid': 'https://orcid.org/0000-0002-1347-995X'}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}, {'id': 'https://openalex.org/I4210097767', 'display_name': 'Kyushu University Hospital', 'ror': 'https://ror.org/00ex2fc97', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I135598925', 'https://openalex.org/I4210097767']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hidefumi Maeda', 'raw_affiliation_strings': ['Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I135598925']}, {'raw_affiliation_string': 'Department of Endodontology, Kyushu University Hospital, Fukuoka 812-8582, Japan', 'institution_ids': ['https://openalex.org/I4210097767']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5010768298'], 'corresponding_institution_ids': ['https://openalex.org/I4210097767'], 'apc_list': {'value': 2200, 'currency': 'CHF', 'value_usd': 2382, 'provenance': 'doaj'}, 'apc_paid': {'value': 2200, 'currency': 'CHF', 'value_usd': 2382, 'provenance': 'doaj'}, 'fwci': 0.636, 'has_fulltext': False, 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.66748, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '10', 'issue': '9', 'first_page': '2491', 'last_page': '2491'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11919', 'display_name': 'Molecular Mechanisms of Tooth Development and Morphogenesis', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11919', 'display_name': 'Molecular Mechanisms of Tooth Development and Morphogenesis', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11570', 'display_name': 'Applications of Platelet-Rich Plasma in Regenerative Medicine', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2748', 'display_name': 'Urology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12367', 'display_name': 'Epidemiology and Management of Traumatic Dental Injuries', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/3604', 'display_name': 'Emergency Medical Services'}, 'field': {'id': 'https://openalex.org/fields/36', 'display_name': 'Health Professions'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dentin-sialophosphoprotein', 'display_name': 'Dentin sialophosphoprotein', 'score': 0.71064496}, {'id': 'https://openalex.org/keywords/dentinogenesis', 'display_name': 'Dentinogenesis', 'score': 0.66072565}, {'id': 'https://openalex.org/keywords/tooth-development', 'display_name': 'Tooth Development', 'score': 0.519734}, {'id': 'https://openalex.org/keywords/primary-dentition', 'display_name': 'Primary Dentition', 'score': 0.51158}, {'id': 'https://openalex.org/keywords/pulpal-healing', 'display_name': 'Pulpal Healing', 'score': 0.501545}], 'concepts': [{'id': 'https://openalex.org/C2520015', 'wikidata': 'https://www.wikidata.org/wiki/Q853338', 'display_name': 'Odontoblast', 'level': 3, 'score': 0.9266348}, {'id': 'https://openalex.org/C2779263046', 'wikidata': 'https://www.wikidata.org/wiki/Q189637', 'display_name': 'Dentin', 'level': 2, 'score': 0.85542023}, {'id': 'https://openalex.org/C2779203663', 'wikidata': 'https://www.wikidata.org/wiki/Q5259528', 'display_name': 'Dentin sialophosphoprotein', 'level': 4, 'score': 0.71064496}, {'id': 'https://openalex.org/C188442228', 'wikidata': 'https://www.wikidata.org/wiki/Q48286', 'display_name': 'Pulp (tooth)', 'level': 2, 'score': 0.68613946}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.66109943}, {'id': 'https://openalex.org/C69103154', 'wikidata': 'https://www.wikidata.org/wiki/Q3023350', 'display_name': 'Dentinogenesis', 'level': 4, 'score': 0.66072565}, {'id': 'https://openalex.org/C104392178', 'wikidata': 'https://www.wikidata.org/wiki/Q351499', 'display_name': 'Ameloblast', 'level': 3, 'score': 0.6306598}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.62188363}, {'id': 'https://openalex.org/C199343813', 'wikidata': 'https://www.wikidata.org/wiki/Q12128', 'display_name': 'Dentistry', 'level': 1, 'score': 0.4443027}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.32909876}, {'id': 'https://openalex.org/C156887251', 'wikidata': 'https://www.wikidata.org/wiki/Q2386424', 'display_name': 'Enamel paint', 'level': 2, 'score': 0.18730304}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.18023303}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.14226109}], 'mesh': [], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/cells10092491', 'pdf_url': 'https://www.mdpi.com/2073-4409/10/9/2491/pdf?version=1632195586', 'source': {'id': 'https://openalex.org/S2736626452', 'display_name': 'Cells', 'issn_l': '2073-4409', 'issn': ['2073-4409'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/da2667cc89ed4cefad66fe158b93686e', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc8468928', 'pdf_url': 'https://europepmc.org/articles/pmc8468928?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/2324/4784527', 'pdf_url': 'https://catalog.lib.kyushu-u.ac.jp/opac_download_md/4784527/dent0864.pdf', 'source': {'id': 'https://openalex.org/S4306400832', 'display_name': 'Kyushu University Institutional Repository (QIR) (Kyushu University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I135598925', 'host_organization_name': 'Kyushu University', 'host_organization_lineage': ['https://openalex.org/I135598925'], 'host_organization_lineage_names': ['Kyushu University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468928', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34572140', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/cells10092491', 'pdf_url': 'https://www.mdpi.com/2073-4409/10/9/2491/pdf?version=1632195586', 'source': {'id': 'https://openalex.org/S2736626452', 'display_name': 'Cells', 'issn_l': '2073-4409', 'issn': ['2073-4409'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.49}], 'grants': [{'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': 'JP18K19651'}, {'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': 'JP21K19608'}, {'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': 'JP21K09876'}], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W1628905767', 'https://openalex.org/W1947430529', 'https://openalex.org/W1966329590', 'https://openalex.org/W1973211134', 'https://openalex.org/W1975087479', 'https://openalex.org/W1976327775', 'https://openalex.org/W1979196043', 'https://openalex.org/W1984199402', 'https://openalex.org/W1997999543', 'https://openalex.org/W1999235557', 'https://openalex.org/W2009292000', 'https://openalex.org/W2011582118', 'https://openalex.org/W2020313523', 'https://openalex.org/W2025827978', 'https://openalex.org/W2026863358', 'https://openalex.org/W2031252651', 'https://openalex.org/W2033696753', 'https://openalex.org/W2039164947', 'https://openalex.org/W2042877808', 'https://openalex.org/W2049056862', 'https://openalex.org/W2056145075', 'https://openalex.org/W2072604447', 'https://openalex.org/W2075749693', 'https://openalex.org/W2082700122', 'https://openalex.org/W2089715703', 'https://openalex.org/W2092003923', 'https://openalex.org/W2095929030', 'https://openalex.org/W2098996143', 'https://openalex.org/W2104165393', 'https://openalex.org/W2104602416', 'https://openalex.org/W2127090737', 'https://openalex.org/W2130516299', 'https://openalex.org/W2133484311', 'https://openalex.org/W2152567646', 'https://openalex.org/W2161512797', 'https://openalex.org/W2162313608', 'https://openalex.org/W2165213969', 'https://openalex.org/W2305113572', 'https://openalex.org/W2408593291', 'https://openalex.org/W2415881821', 'https://openalex.org/W2424447295', 'https://openalex.org/W2462989712', 'https://openalex.org/W2568491470', 'https://openalex.org/W2613726992', 'https://openalex.org/W2765712565', 'https://openalex.org/W2776739402', 'https://openalex.org/W2790624289', 'https://openalex.org/W2892098150', 'https://openalex.org/W2902231542', 'https://openalex.org/W2913784762', 'https://openalex.org/W2917598445', 'https://openalex.org/W2951313231'], 'related_works': ['https://openalex.org/W3112466599', 'https://openalex.org/W2765431588', 'https://openalex.org/W2413903194', 'https://openalex.org/W2338191157', 'https://openalex.org/W2104084780', 'https://openalex.org/W2075356405', 'https://openalex.org/W2062277891', 'https://openalex.org/W1992678279', 'https://openalex.org/W1942059654', 'https://openalex.org/W1520908899'], 'abstract_inverted_index': {'Direct': [0, 148], 'pulp': [1, 10, 15, 103, 149], 'capping': [2, 150], 'is': [3, 177, 182], 'an': [4], 'effective': [5], 'treatment': [6, 151], 'for': [7, 179], 'preserving': [8], 'dental': [9, 76, 102], 'against': [11], 'carious': [12], 'or': [13], 'traumatic': [14], 'exposure': [16], 'via': [17], 'the': [18, 40, 75, 155], 'formation': [19, 29, 128, 143, 156, 188], 'of': [20, 42, 57, 109, 146, 157, 161], 'protective': [21], 'reparative': [22, 66, 162, 186], 'dentin': [23, 28, 67, 163, 187], 'by': [24, 33], 'odontoblast-like': [25], 'cells.': [26, 118], 'Reparative': [27], 'can': [30], 'be': [31, 52], 'stimulated': [32], 'several': [34], 'signaling': [35], 'molecules;': [36], 'therefore,': [37], 'we': [38], 'investigated': [39], 'effects': [41], 'secreted': [43], 'frizzled-related': [44], 'protein': [45], '(SFRP)': [46], '1': [47], 'that': [48, 164, 175], 'was': [49, 95], 'reported': [50], 'to': [51, 169, 191], 'strongly': [53, 96], 'expressed': [54, 91, 97], 'in': [55, 74, 98, 121, 184, 189], 'odontoblasts': [56], 'newborn': [58], 'molar': [59], 'tooth': [60], 'germs': [61], 'on': [62], 'odontoblastic': [63], 'differentiation': [64], 'and': [65, 80, 88, 116, 129, 133, 144, 181], 'formation.': [68], 'In': [69], 'developing': [70], 'rat': [71], 'incisors,': [72], 'cells': [73, 104, 115], 'pulp,': [77], 'cervical': [78], 'loop,': [79], 'inner': [81], 'enamel': [82], 'epithelium,': [83], 'as': [84, 86], 'well': [85], 'ameloblasts': [87], 'preodontoblasts,': [89], 'weakly': [90], 'Sfrp1;': [92], 'however,': [93], 'Sfrp1': [94], 'mature': [99], 'odontoblasts.': [100], 'Human': [101], '(hDPCs)': [105], 'showed': [106], 'stronger': [107], 'expression': [108, 132, 145], 'SFRP1': [110, 119, 139, 153, 176], 'compared': [111], 'with': [112, 152], 'periodontal': [113], 'ligament': [114], 'gingival': [117], 'knockdown': [120], 'hDPCs': [122], 'abolished': [123], 'calcium': [124], 'chloride-induced': [125], 'mineralized': [126], 'nodule': [127, 142], 'odontoblast-related': [130], 'gene': [131, 136], 'decreased': [134], 'BMP-2': [135], 'expression.': [137], 'Conversely,': [138], 'stimulation': [140], 'enhanced': [141], 'BMP-2.': [147], 'induced': [154], 'a': [158, 166], 'considerable': [159], 'amount': [160], 'has': [165], 'structure': [167], 'similar': [168], 'primary': [170], 'dentin.': [171], 'Our': [172], 'results': [173], 'indicate': [174], 'crucial': [178], 'dentinogenesis': [180], 'important': [183], 'promoting': [185], 'response': [190], 'injury.': [192]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3199041259', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 2}], 'updated_date': '2024-09-12T07:23:22.228719', 'created_date': '2021-09-27'}