Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3196482013', 'doi': 'https://doi.org/10.3389/fphar.2021.692346', 'title': 'Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice', 'display_name': 'Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice', 'publication_year': 2021, 'publication_date': '2021-08-26', 'ids': {'openalex': 'https://openalex.org/W3196482013', 'doi': 'https://doi.org/10.3389/fphar.2021.692346', 'mag': '3196482013', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34512328', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8427522'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fphar.2021.692346', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fphar.2021.692346/pdf', 'source': {'id': 'https://openalex.org/S132108250', 'display_name': 'Frontiers in Pharmacology', 'issn_l': '1663-9812', 'issn': ['1663-9812'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fphar.2021.692346/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101995129', 'display_name': 'Xiaohe Li', 'orcid': 'https://orcid.org/0000-0003-4315-5953'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4210112130', 'display_name': 'Tianjin International Joint Academy of Biomedicine', 'ror': 'https://ror.org/01v11cc68', 'country_code': 'CN', 'type': 'other', 'lineage': ['https://openalex.org/I4210112130']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaohe Li', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}, {'raw_affiliation_string': 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China', 'institution_ids': ['https://openalex.org/I4210112130']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101658709', 'display_name': 'Rui Liu', 'orcid': 'https://orcid.org/0000-0002-4515-2708'}, 'institutions': [{'id': 'https://openalex.org/I4210112130', 'display_name': 'Tianjin International Joint Academy of Biomedicine', 'ror': 'https://ror.org/01v11cc68', 'country_code': 'CN', 'type': 'other', 'lineage': ['https://openalex.org/I4210112130']}, {'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Rui Liu', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China', 'institution_ids': ['https://openalex.org/I4210112130']}, {'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006610359', 'display_name': 'Yunyao Cui', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4210112130', 'display_name': 'Tianjin International Joint Academy of Biomedicine', 'ror': 'https://ror.org/01v11cc68', 'country_code': 'CN', 'type': 'other', 'lineage': ['https://openalex.org/I4210112130']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yunyao Cui', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}, {'raw_affiliation_string': 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China', 'institution_ids': ['https://openalex.org/I4210112130']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017944089', 'display_name': 'Jingjing Liang', 'orcid': 'https://orcid.org/0000-0002-4623-9864'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4210112130', 'display_name': 'Tianjin International Joint Academy of Biomedicine', 'ror': 'https://ror.org/01v11cc68', 'country_code': 'CN', 'type': 'other', 'lineage': ['https://openalex.org/I4210112130']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jingjing Liang', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}, {'raw_affiliation_string': 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China', 'institution_ids': ['https://openalex.org/I4210112130']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043099928', 'display_name': 'Zhun Bi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhun Bi', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101417936', 'display_name': 'Shimeng Li', 'orcid': 'https://orcid.org/0000-0003-4004-1707'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}, {'id': 'https://openalex.org/I4210112130', 'display_name': 'Tianjin International Joint Academy of Biomedicine', 'ror': 'https://ror.org/01v11cc68', 'country_code': 'CN', 'type': 'other', 'lineage': ['https://openalex.org/I4210112130']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shimeng Li', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}, {'raw_affiliation_string': 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China', 'institution_ids': ['https://openalex.org/I4210112130']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101519892', 'display_name': 'Miao Yang', 'orcid': 'https://orcid.org/0000-0001-7760-0432'}, 'institutions': [{'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yang Miao', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100425151', 'display_name': 'Liang Zhang', 'orcid': 'https://orcid.org/0000-0001-8448-6754'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Liang Zhang', 'raw_affiliation_strings': ['Department of Thoracic Surgery, Tian Jin First Central Hospital, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic Surgery, Tian Jin First Central Hospital, Tianjin, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100397108', 'display_name': 'Xiaoping Li', 'orcid': 'https://orcid.org/0000-0002-0603-0820'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaoping Li', 'raw_affiliation_strings': ['Department of Thoracic Surgery, Tian Jin First Central Hospital, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic Surgery, Tian Jin First Central Hospital, Tianjin, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085610505', 'display_name': 'Honggang Zhou', 'orcid': 'https://orcid.org/0000-0003-2987-3422'}, 'institutions': [{'id': 'https://openalex.org/I4210112130', 'display_name': 'Tianjin International Joint Academy of Biomedicine', 'ror': 'https://ror.org/01v11cc68', 'country_code': 'CN', 'type': 'other', 'lineage': ['https://openalex.org/I4210112130']}, {'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Honggang Zhou', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China', 'institution_ids': ['https://openalex.org/I4210112130']}, {'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013811376', 'display_name': 'Cheng Yang', 'orcid': 'https://orcid.org/0000-0001-9431-290X'}, 'institutions': [{'id': 'https://openalex.org/I4210112130', 'display_name': 'Tianjin International Joint Academy of Biomedicine', 'ror': 'https://ror.org/01v11cc68', 'country_code': 'CN', 'type': 'other', 'lineage': ['https://openalex.org/I4210112130']}, {'id': 'https://openalex.org/I205237279', 'display_name': 'Nankai University', 'ror': 'https://ror.org/01y1kjr75', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I205237279']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Cheng Yang', 'raw_affiliation_strings': ['State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China'], 'affiliations': [{'raw_affiliation_string': 'Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China', 'institution_ids': ['https://openalex.org/I4210112130']}, {'raw_affiliation_string': 'State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China', 'institution_ids': ['https://openalex.org/I205237279']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5085610505'], 'corresponding_institution_ids': ['https://openalex.org/I4210112130', 'https://openalex.org/I205237279'], 'apc_list': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'apc_paid': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'fwci': 1.308, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.820125, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '12', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10870', 'display_name': 'Idiopathic Pulmonary Fibrosis: Diagnosis and Management', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10870', 'display_name': 'Idiopathic Pulmonary Fibrosis: Diagnosis and Management', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10143', 'display_name': 'Standardisation and Management of COPD', 'score': 0.9919, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10322', 'display_name': 'Mechanical Ventilation in Respiratory Failure and ARDS', 'score': 0.987, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/sequela', 'display_name': 'Sequela', 'score': 0.61710304}, {'id': 'https://openalex.org/keywords/pulmonary-disease', 'display_name': 'pulmonary disease', 'score': 0.518315}, {'id': 'https://openalex.org/keywords/lung-fibrosis', 'display_name': 'Lung Fibrosis', 'score': 0.514728}, {'id': 'https://openalex.org/keywords/respiratory', 'display_name': 'Respiratory', 'score': 0.503135}, {'id': 'https://openalex.org/keywords/pirfenidone', 'display_name': 'Pirfenidone', 'score': 0.4582559}], 'concepts': [{'id': 'https://openalex.org/C2776232574', 'wikidata': 'https://www.wikidata.org/wiki/Q415571', 'display_name': 'Bleomycin', 'level': 3, 'score': 0.9469577}, {'id': 'https://openalex.org/C2781244666', 'wikidata': 'https://www.wikidata.org/wiki/Q32446', 'display_name': 'Pulmonary fibrosis', 'level': 3, 'score': 0.92621017}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.82639885}, {'id': 'https://openalex.org/C2777609351', 'wikidata': 'https://www.wikidata.org/wiki/Q3089469', 'display_name': 'Sequela', 'level': 2, 'score': 0.61710304}, {'id': 'https://openalex.org/C2780559512', 'wikidata': 'https://www.wikidata.org/wiki/Q605709', 'display_name': 'Fibrosis', 'level': 2, 'score': 0.6041809}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.58894175}, {'id': 'https://openalex.org/C2778341716', 'wikidata': 'https://www.wikidata.org/wiki/Q2290446', 'display_name': 'Idiopathic pulmonary fibrosis', 'level': 3, 'score': 0.55714774}, {'id': 'https://openalex.org/C75603125', 'wikidata': 'https://www.wikidata.org/wiki/Q1877462', 'display_name': 'Pulmonary function testing', 'level': 2, 'score': 0.52972}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.47814143}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.46707466}, {'id': 'https://openalex.org/C2779832356', 'wikidata': 'https://www.wikidata.org/wiki/Q2060696', 'display_name': 'Pirfenidone', 'level': 4, 'score': 0.4582559}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.38333917}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.20625165}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.08754584}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.057200223}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.056370974}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fphar.2021.692346', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fphar.2021.692346/pdf', 'source': {'id': 'https://openalex.org/S132108250', 'display_name': 'Frontiers in Pharmacology', 'issn_l': '1663-9812', 'issn': ['1663-9812'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/ecbab47a2cfb4fc6bab71b2e711a94d4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427522', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fphar.2021.692346', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fphar.2021.692346/pdf', 'source': {'id': 'https://openalex.org/S132108250', 'display_name': 'Frontiers in Pharmacology', 'issn_l': '1663-9812', 'issn': ['1663-9812'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.88}], 'grants': [{'funder': 'https://openalex.org/F4320327720', 'funder_display_name': 'Foundation for Innovative Research Groups of the National Natural Science Foundation of China', 'award_id': '82070060, 82000073'}, {'funder': 'https://openalex.org/F4320336756', 'funder_display_name': 'Tianjin Science and Technology Program', 'award_id': '501100019065'}], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1585502126', 'https://openalex.org/W1980321651', 'https://openalex.org/W1993559550', 'https://openalex.org/W2000632234', 'https://openalex.org/W2053375738', 'https://openalex.org/W2106408170', 'https://openalex.org/W2111791469', 'https://openalex.org/W2111861407', 'https://openalex.org/W2114054457', 'https://openalex.org/W2120094753', 'https://openalex.org/W2120446140', 'https://openalex.org/W2149707805', 'https://openalex.org/W2271349749', 'https://openalex.org/W2292021561', 'https://openalex.org/W2610199736', 'https://openalex.org/W2758783533', 'https://openalex.org/W2905659660', 'https://openalex.org/W2935101654', 'https://openalex.org/W2953224333', 'https://openalex.org/W2968467102', 'https://openalex.org/W2978686205', 'https://openalex.org/W2991491848', 'https://openalex.org/W3003788575', 'https://openalex.org/W3004318991', 'https://openalex.org/W3005079553', 'https://openalex.org/W3006354146', 'https://openalex.org/W3006564542', 'https://openalex.org/W3006645647', 'https://openalex.org/W3008801544', 'https://openalex.org/W3009925957', 'https://openalex.org/W3011528304', 'https://openalex.org/W3014708904', 'https://openalex.org/W3015718134', 'https://openalex.org/W3026032531', 'https://openalex.org/W3027630905', 'https://openalex.org/W3032677067', 'https://openalex.org/W3034773147', 'https://openalex.org/W3040155643', 'https://openalex.org/W3080718665'], 'related_works': ['https://openalex.org/W4367052859', 'https://openalex.org/W4214608853', 'https://openalex.org/W2979280297', 'https://openalex.org/W2889209983', 'https://openalex.org/W2598760175', 'https://openalex.org/W2460409169', 'https://openalex.org/W2358667551', 'https://openalex.org/W2142773430', 'https://openalex.org/W2091120910', 'https://openalex.org/W1969070671'], 'abstract_inverted_index': {'Pulmonary': [0, 41], 'fibrosis': [1, 27, 42, 83, 92, 173, 183], 'is': [2], 'a': [3, 24, 77], 'known': [4], 'sequela': [5], 'of': [6, 46, 67, 80, 88, 102, 123, 171, 181], 'severe': [7, 34], 'or': [8], 'persistent': [9], 'lung': [10, 105, 150], 'damage.': [11], 'Existing': [12], 'clinical,': [13], 'imaging': [14], 'and': [15, 95, 107, 126, 137, 153, 174], 'autopsy': [16], 'studies': [17], 'have': [18], 'shown': [19], 'that': [20, 130, 145, 164], 'the': [21, 47, 64, 68, 86, 98, 121, 127, 169, 179], 'lungs': [22], 'exhibit': [23], 'pathological': [25], 'pulmonary': [26, 73, 82, 91, 139, 172, 182], 'phenotype': [28], 'after': [29], 'infection': [30], 'with': [31, 52, 186], 'coronaviruses,': [32], 'including': [33], 'acute': [35], 'respiratory': [36], 'syndrome': [37], 'coronavirus': [38, 53], '2': [39], '(SARS-CoV-2).': [40], 'may': [43], 'be': [44], 'one': [45], 'most': [48], 'serious': [49], 'sequelae': [50], 'associated': [51], 'disease': [54], '2019': [55], '(COVID-19).': [56], 'In': [57, 141], 'this': [58], 'study,': [59], 'we': [60], 'aimed': [61], 'to': [62, 84, 158], 'examine': [63], 'preventative': [65], 'effects': [66, 87], 'antiviral': [69], 'drug': [70], 'remdesivir': [71, 89, 103, 116, 131, 146, 165], 'on': [72, 90, 120], 'fibrosis.': [74], 'We': [75], 'used': [76], 'mouse': [78], 'model': [79], 'bleomycin-induced': [81, 134], 'evaluate': [85], 'in': [93, 104, 111, 184], 'vivo': [94], 'further': [96], 'explored': [97], 'potential': [99], 'pharmacological': [100], 'mechanisms': [101], 'fibroblasts': [106], 'alveolar': [108, 156], 'epithelial': [109, 157], 'cells': [110], 'vitro': [112, 142], '.': [113], 'The': [114], 'preventive': [115], 'treatment': [117], 'was': [118], 'started': [119], 'day': [122], 'bleomycin': [124], 'installation,': [125], 'results': [128, 162], 'showed': [129, 144], 'significantly': [132], 'alleviated': [133], 'collagen': [135], 'deposition': [136], 'improved': [138, 154], 'function.': [140], 'experiments': [143], 'dose-dependently': [147], 'suppressed': [148], 'TGF-β1-induced': [149, 155], 'fibroblast': [151], 'activation': [152], 'mesenchymal': [159], 'transition.': [160], 'Our': [161], 'indicate': [163], 'can': [166], 'preventatively': [167], 'alleviate': [168], 'severity': [170], 'provide': [175], 'some': [176], 'reference': [177], 'for': [178], 'prevention': [180], 'patients': [185], 'COVID-19.': [187]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3196482013', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}], 'updated_date': '2024-09-13T10:07:46.481267', 'created_date': '2021-09-13'}