Publication Information

{'id': 'https://openalex.org/W3196460129', 'doi': 'https://doi.org/10.37489/0235-2990-2021-66-5-6-4-10', 'title': 'Possibilities of suppressing the cytopathogenic effect of SARS-CoV-2 coronavirus according to the results of the antiviral activity of Cytovir®-3 <i>in vitro</i> study', 'display_name': 'Possibilities of suppressing the cytopathogenic effect of SARS-CoV-2 coronavirus according to the results of the antiviral activity of Cytovir®-3 <i>in vitro</i> study', 'publication_year': 2021, 'publication_date': '2021-08-30', 'ids': {'openalex': 'https://openalex.org/W3196460129', 'doi': 'https://doi.org/10.37489/0235-2990-2021-66-5-6-4-10', 'mag': '3196460129'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.37489/0235-2990-2021-66-5-6-4-10', 'pdf_url': 'https://www.antibiotics-chemotherapy.ru/jour/article/download/813/782', 'source': {'id': 'https://openalex.org/S4210214015', 'display_name': 'Antibiot Khimioter = Antibiotics and Chemotherapy', 'issn_l': '0235-2990', 'issn': ['0235-2990'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://www.antibiotics-chemotherapy.ru/jour/article/download/813/782', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5020763673', 'display_name': 'В. С. Смирнов', 'orcid': 'https://orcid.org/0000-0002-2723-1496'}, 'institutions': [{'id': 'https://openalex.org/I4210101453', 'display_name': 'Saint Petersburg Pasteur Institute', 'ror': 'https://ror.org/00kcctq66', 'country_code': 'RU', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210101453']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'V. S. Smirnov', 'raw_affiliation_strings': ['Saint-Petersburg Pasteur Institute'], 'affiliations': [{'raw_affiliation_string': 'Saint-Petersburg Pasteur Institute', 'institution_ids': ['https://openalex.org/I4210101453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070901028', 'display_name': 'И. А. Ленева', 'orcid': 'https://orcid.org/0000-0002-7755-2714'}, 'institutions': [{'id': 'https://openalex.org/I4210130895', 'display_name': 'Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences', 'ror': 'https://ror.org/03bk73w20', 'country_code': 'RU', 'type': 'facility', 'lineage': ['https://openalex.org/I1313323035', 'https://openalex.org/I4210110862', 'https://openalex.org/I4210130895']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'I. A. Leneva', 'raw_affiliation_strings': ['I. I. Mechnikov Research Institute of Vaccines and Sera'], 'affiliations': [{'raw_affiliation_string': 'I. I. Mechnikov Research Institute of Vaccines and Sera', 'institution_ids': ['https://openalex.org/I4210130895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111406055', 'display_name': 'T. A. Kudryavtseva', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210133092', 'display_name': 'Czech Academy of Sciences, Institute of Experimental Medicine', 'ror': 'https://ror.org/03hjekm25', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I202391551', 'https://openalex.org/I4210133092']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'T. A. Kudryavtseva', 'raw_affiliation_strings': ['Institute of Experimental Medicine'], 'affiliations': [{'raw_affiliation_string': 'Institute of Experimental Medicine', 'institution_ids': ['https://openalex.org/I4210133092']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112268890', 'display_name': 'E. B. Fayzuloev', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210130895', 'display_name': 'Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences', 'ror': 'https://ror.org/03bk73w20', 'country_code': 'RU', 'type': 'facility', 'lineage': ['https://openalex.org/I1313323035', 'https://openalex.org/I4210110862', 'https://openalex.org/I4210130895']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'E. B. Fayzuloev', 'raw_affiliation_strings': ['I. I. Mechnikov Research Institute of Vaccines and Sera'], 'affiliations': [{'raw_affiliation_string': 'I. I. Mechnikov Research Institute of Vaccines and Sera', 'institution_ids': ['https://openalex.org/I4210130895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037842797', 'display_name': 'В. А. Заплутанов', 'orcid': 'https://orcid.org/0000-0001-5294-6533'}, 'institutions': [{'id': 'https://openalex.org/I4210130434', 'display_name': 'Petersburg Nuclear Physics Institute', 'ror': 'https://ror.org/037styt87', 'country_code': 'RU', 'type': 'facility', 'lineage': ['https://openalex.org/I1313323035', 'https://openalex.org/I4210096333', 'https://openalex.org/I4210130434']}, {'id': 'https://openalex.org/I2800235667', 'display_name': 'Kurchatov Institute', 'ror': 'https://ror.org/00n1nz186', 'country_code': 'RU', 'type': 'facility', 'lineage': ['https://openalex.org/I2800235667']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'V. A. Zaplutanov', 'raw_affiliation_strings': ['Petersburg Nuclear Physics Institute named by B. P. Konstantinov of National Research Centre «Kurchatov Institute»'], 'affiliations': [{'raw_affiliation_string': 'Petersburg Nuclear Physics Institute named by B. P. Konstantinov of National Research Centre «Kurchatov Institute»', 'institution_ids': ['https://openalex.org/I4210130434', 'https://openalex.org/I2800235667']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007965870', 'display_name': 'С. В. Петленко', 'orcid': 'https://orcid.org/0000-0002-2752-4598'}, 'institutions': [{'id': 'https://openalex.org/I64264942', 'display_name': 'Federal Medical-Biological Agency', 'ror': 'https://ror.org/052ay8m85', 'country_code': 'RU', 'type': 'government', 'lineage': ['https://openalex.org/I64264942']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'S. V. Petlenko', 'raw_affiliation_strings': ['Scientific and Clinical Center of Toxicology named after Academician S. N. Golikov of the Federal Medical and Biological Agency'], 'affiliations': [{'raw_affiliation_string': 'Scientific and Clinical Center of Toxicology named after Academician S. N. Golikov of the Federal Medical and Biological Agency', 'institution_ids': ['https://openalex.org/I64264942']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088304182', 'display_name': 'Н. П. Карташова', 'orcid': 'https://orcid.org/0000-0003-2096-5080'}, 'institutions': [{'id': 'https://openalex.org/I4210130895', 'display_name': 'Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences', 'ror': 'https://ror.org/03bk73w20', 'country_code': 'RU', 'type': 'facility', 'lineage': ['https://openalex.org/I1313323035', 'https://openalex.org/I4210110862', 'https://openalex.org/I4210130895']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'N. P. Kartashova', 'raw_affiliation_strings': ['I. I. Mechnikov Research Institute of Vaccines and Sera'], 'affiliations': [{'raw_affiliation_string': 'I. I. Mechnikov Research Institute of Vaccines and Sera', 'institution_ids': ['https://openalex.org/I4210130895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013053131', 'display_name': 'A. V. Gracheva', 'orcid': 'https://orcid.org/0000-0001-8428-4482'}, 'institutions': [{'id': 'https://openalex.org/I4210130895', 'display_name': 'Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences', 'ror': 'https://ror.org/03bk73w20', 'country_code': 'RU', 'type': 'facility', 'lineage': ['https://openalex.org/I1313323035', 'https://openalex.org/I4210110862', 'https://openalex.org/I4210130895']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'A. V. Gracheva', 'raw_affiliation_strings': ['I. I. Mechnikov Research Institute of Vaccines and Sera'], 'affiliations': [{'raw_affiliation_string': 'I. I. Mechnikov Research Institute of Vaccines and Sera', 'institution_ids': ['https://openalex.org/I4210130895']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5033439372', 'display_name': 'E. R. Korchevaya', 'orcid': 'https://orcid.org/0000-0002-6417-3301'}, 'institutions': [{'id': 'https://openalex.org/I4210130895', 'display_name': 'Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences', 'ror': 'https://ror.org/03bk73w20', 'country_code': 'RU', 'type': 'facility', 'lineage': ['https://openalex.org/I1313323035', 'https://openalex.org/I4210110862', 'https://openalex.org/I4210130895']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'E. R. Korchevaya', 'raw_affiliation_strings': ['I. I. Mechnikov Research Institute of Vaccines and Sera'], 'affiliations': [{'raw_affiliation_string': 'I. I. Mechnikov Research Institute of Vaccines and Sera', 'institution_ids': ['https://openalex.org/I4210130895']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.267, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.587743, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 76, 'max': 78}, 'biblio': {'volume': '66', 'issue': '5-6', 'first_page': '4', 'last_page': '10'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10118', 'display_name': 'SARS-CoV-2 and COVID-19 Research', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10118', 'display_name': 'SARS-CoV-2 and COVID-19 Research', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10211', 'display_name': 'Computational Drug Discovery Methods', 'score': 0.9783, 'subfield': {'id': 'https://openalex.org/subfields/1703', 'display_name': 'Computational Theory and Mathematics'}, 'field': {'id': 'https://openalex.org/fields/17', 'display_name': 'Computer Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11337', 'display_name': 'Tryptophan and brain disorders', 'score': 0.9651, 'subfield': {'id': 'https://openalex.org/subfields/2803', 'display_name': 'Biological Psychiatry'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/vero-cell', 'display_name': 'Vero cell', 'score': 0.8913934}, {'id': 'https://openalex.org/keywords/antiviral-drug', 'display_name': 'Antiviral drug', 'score': 0.6164295}, {'id': 'https://openalex.org/keywords/microculture', 'display_name': 'Microculture', 'score': 0.5241647}, {'id': 'https://openalex.org/keywords/coronavirus', 'display_name': 'Coronavirus', 'score': 0.46589506}], 'concepts': [{'id': 'https://openalex.org/C89138240', 'wikidata': 'https://www.wikidata.org/wiki/Q3066564', 'display_name': 'Vero cell', 'level': 3, 'score': 0.8913934}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.69099075}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.66546404}, {'id': 'https://openalex.org/C2779756493', 'wikidata': 'https://www.wikidata.org/wiki/Q846227', 'display_name': 'Antiviral drug', 'level': 3, 'score': 0.6164295}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.59669685}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.55009574}, {'id': 'https://openalex.org/C2780035454', 'wikidata': 'https://www.wikidata.org/wiki/Q8386', 'display_name': 'Drug', 'level': 2, 'score': 0.54764575}, {'id': 'https://openalex.org/C49377226', 'wikidata': 'https://www.wikidata.org/wiki/Q6839421', 'display_name': 'Microculture', 'level': 3, 'score': 0.5241647}, {'id': 'https://openalex.org/C2777648638', 'wikidata': 'https://www.wikidata.org/wiki/Q57751738', 'display_name': 'Coronavirus', 'level': 5, 'score': 0.46589506}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.4180497}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36613214}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.36355335}, {'id': 'https://openalex.org/C3008058167', 'wikidata': 'https://www.wikidata.org/wiki/Q84263196', 'display_name': 'Coronavirus disease 2019 (COVID-19)', 'level': 4, 'score': 0.35002142}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.2801988}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.09554741}, {'id': 'https://openalex.org/C524204448', 'wikidata': 'https://www.wikidata.org/wiki/Q788926', 'display_name': 'Infectious disease (medical specialty)', 'level': 3, 'score': 0.06053847}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.37489/0235-2990-2021-66-5-6-4-10', 'pdf_url': 'https://www.antibiotics-chemotherapy.ru/jour/article/download/813/782', 'source': {'id': 'https://openalex.org/S4210214015', 'display_name': 'Antibiot Khimioter = Antibiotics and Chemotherapy', 'issn_l': '0235-2990', 'issn': ['0235-2990'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.37489/0235-2990-2021-66-5-6-4-10', 'pdf_url': 'https://www.antibiotics-chemotherapy.ru/jour/article/download/813/782', 'source': {'id': 'https://openalex.org/S4210214015', 'display_name': 'Antibiot Khimioter = Antibiotics and Chemotherapy', 'issn_l': '0235-2990', 'issn': ['0235-2990'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.83}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1996359115', 'https://openalex.org/W2587525763', 'https://openalex.org/W2600589974', 'https://openalex.org/W2766931063', 'https://openalex.org/W3008589801', 'https://openalex.org/W3016084006', 'https://openalex.org/W3019596330', 'https://openalex.org/W3020896479', 'https://openalex.org/W3024966630', 'https://openalex.org/W3025221573', 'https://openalex.org/W3043065230', 'https://openalex.org/W3043257434', 'https://openalex.org/W3044986275', 'https://openalex.org/W3126064815', 'https://openalex.org/W3126172375'], 'related_works': ['https://openalex.org/W4396692128', 'https://openalex.org/W4392912693', 'https://openalex.org/W3199341849', 'https://openalex.org/W3196460129', 'https://openalex.org/W3048757376', 'https://openalex.org/W3041597184', 'https://openalex.org/W3032934539', 'https://openalex.org/W3010548836', 'https://openalex.org/W2114551787', 'https://openalex.org/W1563419202'], 'abstract_inverted_index': {'Introduction': [0], '.': [1], 'The': [2, 42, 72, 98, 234], 'COVID-19': [3], 'pandemic': [4], 'has': [5, 245], 'stimulated': [6], 'the': [7, 16, 21, 50, 62, 66, 76, 82, 103, 118, 122, 125, 135, 141, 145, 154, 168, 177, 191, 197, 207, 215, 223, 228, 242, 250, 259], 'search': [8, 28], 'for': [9], 'drugs': [10, 33], 'with': [11, 34], 'specific': [12], 'antiviral': [13, 51, 73, 231, 235], 'activity': [14, 52, 74, 143, 193, 236], 'against': [15, 38, 81, 241], 'new': [17], 'pathogenic': [18], 'strain': [19], 'of': [20, 25, 44, 53, 65, 75, 121, 124, 134, 144, 180, 194, 230, 237, 252, 263], 'SARS-CoV-2': [22, 67, 83, 195, 243], 'coronavirus.': [23], 'First': [24], 'all,': [26], 'scientific': [27], 'was': [29, 47, 85, 138, 147, 151, 212], 'aimed': [30], 'at': [31, 176], 'studying': [32], 'already': [35], 'proven': [36, 247], 'efficacy': [37], 'influenza': [39], 'and': [40, 70, 102, 129, 159, 162, 183], 'ARVI.': [41], 'aim': [43], 'this': [45], 'work': [46], 'to': [48, 61, 116, 153, 203, 249], 'study': [49], 'Cytovir': [54, 78, 187, 238], '®': [55, 79, 188, 239], '-3': [56, 80, 189, 240], 'in': [57, 59, 87, 90, 196, 227], 'vitro': [58, 91], 'relation': [60], 'cytopathogenic': [63], 'effect': [64], 'virus.': [68], 'Material': [69], 'methods.': [71], 'drug': [77, 146, 178, 216], 'virus': [84, 244], 'studied': [86], 'experimental': [88], 'models': [89], 'on': [92, 222], 'Vero': [93, 224], 'CCL81': [94], 'cell': [95, 225], 'culture': [96, 226], '(ATCC).': [97], 'maximum': [99, 260], 'tolerated': [100, 261], 'concentration': [101], '50%': [104], 'cytotoxic': [105, 220], 'dose': [106, 198, 262], 'were': [107], 'determined': [108], 'using': [109], 'a': [110, 132], 'quantitative': [111], 'microculture': [112], 'tetrazolium': [113], 'test': [114, 126], 'assay': [115], 'calculate': [117], 'working': [119], 'range': [120, 199, 229], 'concentrations': [123, 179], 'drug.': [127], 'Results': [128], 'discussion.': [130], 'As': [131], 'result': [133], 'study,': [136], 'it': [137, 150], 'shown': [139], 'that': [140, 214], 'greatest': [142], 'manifested': [148], 'when': [149], 'added': [152], 'cells': [155], '24': [156, 163], 'hours': [157, 164], 'before': [158], '1': [160], 'hour': [161], 'after': [165], 'viral': [166, 192], 'infection,': [167], 'inhibition': [169], 'level': [170], 'reached': [171], '53%': [172], '(>IC': [173], '50': [174, 254], ')': [175], '105,': [181], '55,': [182], '85': [184], 'µg/ml,': [185], 'respectively.': [186], 'suppressed': [190], 'from': [200], '10': [201], 'µg/ml': [202, 205], '105': [204], 'under': [206], 'indicated': [208], 'infection': [209], 'conditions.': [210], 'It': [211], 'found': [213], 'did': [217], 'not': [218], 'exhibit': [219], 'effects': [221], 'doses.': [232], 'Conclusion.': [233], 'been': [246], 'due': [248], 'achievement': [251], 'IC': [253], ',': [255], 'which': [256], 'is': [257], 'below': [258], '149': [264], 'µg/ml.': [265]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3196460129', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2025-01-03T02:57:01.991325', 'created_date': '2021-09-13'}