Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3190446843', 'doi': 'https://doi.org/10.3389/fcvm.2021.704281', 'title': 'Antidepressant Drugs Effects on Blood Pressure', 'display_name': 'Antidepressant Drugs Effects on Blood Pressure', 'publication_year': 2021, 'publication_date': '2021-08-03', 'ids': {'openalex': 'https://openalex.org/W3190446843', 'doi': 'https://doi.org/10.3389/fcvm.2021.704281', 'mag': '3190446843', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34414219', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8370473'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fcvm.2021.704281', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fcvm.2021.704281/pdf', 'source': {'id': 'https://openalex.org/S2595413687', 'display_name': 'Frontiers in Cardiovascular Medicine', 'issn_l': '2297-055X', 'issn': ['2297-055X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fcvm.2021.704281/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033061426', 'display_name': 'Anna Calvi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I124601658', 'display_name': 'University of Parma', 'ror': 'https://ror.org/02k7wn190', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I124601658']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Anna Calvi', 'raw_affiliation_strings': ['Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy', 'institution_ids': ['https://openalex.org/I124601658']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016242267', 'display_name': 'Ilaria Fischetti', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I124601658', 'display_name': 'University of Parma', 'ror': 'https://ror.org/02k7wn190', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I124601658']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Ilaria Fischetti', 'raw_affiliation_strings': ['Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy', 'institution_ids': ['https://openalex.org/I124601658']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052915872', 'display_name': 'Ignazio Verzicco', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I124601658', 'display_name': 'University of Parma', 'ror': 'https://ror.org/02k7wn190', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I124601658']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Ignazio Verzicco', 'raw_affiliation_strings': ['Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy', 'institution_ids': ['https://openalex.org/I124601658']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069568589', 'display_name': 'Martino Belvederi Murri', 'orcid': 'https://orcid.org/0000-0002-7262-3528'}, 'institutions': [{'id': 'https://openalex.org/I201324441', 'display_name': 'University of Ferrara', 'ror': 'https://ror.org/041zkgm14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I201324441']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Martino Belvederi Murri', 'raw_affiliation_strings': ['Department of Neuroscience and Rehabilitation, Institute of Psychiatry, University of Ferrara, Ferrara, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Neuroscience and Rehabilitation, Institute of Psychiatry, University of Ferrara, Ferrara, Italy', 'institution_ids': ['https://openalex.org/I201324441']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006934094', 'display_name': 'Stamatula Zanetidou', 'orcid': None}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Stamatula Zanetidou', 'raw_affiliation_strings': ['Research Group on Mental and Physical Health of the Elderly (ARISMA), Bologna, Italy'], 'affiliations': [{'raw_affiliation_string': 'Research Group on Mental and Physical Health of the Elderly (ARISMA), Bologna, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080053772', 'display_name': 'Riccardo Volpi', 'orcid': 'https://orcid.org/0000-0001-8653-6217'}, 'institutions': [{'id': 'https://openalex.org/I124601658', 'display_name': 'University of Parma', 'ror': 'https://ror.org/02k7wn190', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I124601658']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Riccardo Volpi', 'raw_affiliation_strings': ['Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy', 'institution_ids': ['https://openalex.org/I124601658']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020406433', 'display_name': 'Pietro Coghi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I124601658', 'display_name': 'University of Parma', 'ror': 'https://ror.org/02k7wn190', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I124601658']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Pietro Coghi', 'raw_affiliation_strings': ['Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy', 'institution_ids': ['https://openalex.org/I124601658']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079253305', 'display_name': 'Stefano Tedeschi', 'orcid': 'https://orcid.org/0000-0003-0895-2981'}, 'institutions': [{'id': 'https://openalex.org/I124601658', 'display_name': 'University of Parma', 'ror': 'https://ror.org/02k7wn190', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I124601658']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Stefano Tedeschi', 'raw_affiliation_strings': ['Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy', 'institution_ids': ['https://openalex.org/I124601658']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016977611', 'display_name': 'Mario Amore', 'orcid': 'https://orcid.org/0000-0003-2927-2192'}, 'institutions': [{'id': 'https://openalex.org/I83816512', 'display_name': 'University of Genoa', 'ror': 'https://ror.org/0107c5v14', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I83816512']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210146472', 'display_name': 'Ospedale Policlinico San Martino', 'ror': 'https://ror.org/04d7es448', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146472', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Mario Amore', 'raw_affiliation_strings': ['Section of Psychiatry, Department of Neuroscience, Ophthalmology, Genetics, and Infant-Maternal Science, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy'], 'affiliations': [{'raw_affiliation_string': 'Section of Psychiatry, Department of Neuroscience, Ophthalmology, Genetics, and Infant-Maternal Science, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy', 'institution_ids': ['https://openalex.org/I83816512', 'https://openalex.org/I4210153126', 'https://openalex.org/I4210146472']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5030395542', 'display_name': 'Aderville Cabassi', 'orcid': 'https://orcid.org/0000-0001-8262-5669'}, 'institutions': [{'id': 'https://openalex.org/I124601658', 'display_name': 'University of Parma', 'ror': 'https://ror.org/02k7wn190', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I124601658']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Aderville Cabassi', 'raw_affiliation_strings': ['Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiorenal and Hypertension Research Unit, Physiopathology Unit, Clinica Medica Generale e Terapia Medica, Department of Medicine and Surgery (DIMEC), University of Parma, Parma, Italy', 'institution_ids': ['https://openalex.org/I124601658']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5030395542'], 'corresponding_institution_ids': ['https://openalex.org/I124601658'], 'apc_list': {'value': 2490, 'currency': 'USD', 'value_usd': 2490, 'provenance': 'doaj'}, 'apc_paid': {'value': 2490, 'currency': 'USD', 'value_usd': 2490, 'provenance': 'doaj'}, 'fwci': 3.588, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 64, 'citation_normalized_percentile': {'value': 0.510617, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '8', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11950', 'display_name': 'Cardiovascular Syncope and Autonomic Disorders', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11950', 'display_name': 'Cardiovascular Syncope and Autonomic Disorders', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10745', 'display_name': 'Heart Rate Variability and Autonomic Control', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11071', 'display_name': 'Treatment of Major Depression', 'score': 0.9921, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bupropion', 'display_name': 'Bupropion', 'score': 0.7523439}, {'id': 'https://openalex.org/keywords/nefazodone', 'display_name': 'Nefazodone', 'score': 0.5659878}, {'id': 'https://openalex.org/keywords/trazodone', 'display_name': 'Trazodone', 'score': 0.48145217}, {'id': 'https://openalex.org/keywords/reuptake', 'display_name': 'Reuptake', 'score': 0.47979265}, {'id': 'https://openalex.org/keywords/mirtazapine', 'display_name': 'Mirtazapine', 'score': 0.45475873}, {'id': 'https://openalex.org/keywords/reboxetine', 'display_name': 'Reboxetine', 'score': 0.45329943}], 'concepts': [{'id': 'https://openalex.org/C2779908668', 'wikidata': 'https://www.wikidata.org/wiki/Q834280', 'display_name': 'Bupropion', 'level': 3, 'score': 0.7523439}, {'id': 'https://openalex.org/C2779177272', 'wikidata': 'https://www.wikidata.org/wiki/Q76560', 'display_name': 'Antidepressant', 'level': 3, 'score': 0.7232344}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.69573146}, {'id': 'https://openalex.org/C2776466888', 'wikidata': 'https://www.wikidata.org/wiki/Q898407', 'display_name': 'Venlafaxine', 'level': 4, 'score': 0.6305123}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.62892056}, {'id': 'https://openalex.org/C2779419675', 'wikidata': 'https://www.wikidata.org/wiki/Q416632', 'display_name': 'Nefazodone', 'level': 5, 'score': 0.5659878}, {'id': 'https://openalex.org/C73787029', 'wikidata': 'https://www.wikidata.org/wiki/Q7104929', 'display_name': 'Orthostatic vital signs', 'level': 3, 'score': 0.50192904}, {'id': 'https://openalex.org/C2778514916', 'wikidata': 'https://www.wikidata.org/wiki/Q186242', 'display_name': 'Norepinephrine', 'level': 3, 'score': 0.49954653}, {'id': 'https://openalex.org/C2780980600', 'wikidata': 'https://www.wikidata.org/wiki/Q411457', 'display_name': 'Trazodone', 'level': 4, 'score': 0.48145217}, {'id': 'https://openalex.org/C99631742', 'wikidata': 'https://www.wikidata.org/wiki/Q22290476', 'display_name': 'Reuptake', 'level': 4, 'score': 0.47979265}, {'id': 'https://openalex.org/C2781068410', 'wikidata': 'https://www.wikidata.org/wiki/Q421930', 'display_name': 'Mirtazapine', 'level': 4, 'score': 0.45475873}, {'id': 'https://openalex.org/C2780467756', 'wikidata': 'https://www.wikidata.org/wiki/Q418970', 'display_name': 'Reboxetine', 'level': 5, 'score': 0.45329943}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.42238295}, {'id': 'https://openalex.org/C31487548', 'wikidata': 'https://www.wikidata.org/wiki/Q4859664', 'display_name': 'Reuptake inhibitor', 'level': 4, 'score': 0.3718416}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.37012446}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34614772}, {'id': 'https://openalex.org/C2775864247', 'wikidata': 'https://www.wikidata.org/wiki/Q167934', 'display_name': 'Serotonin', 'level': 3, 'score': 0.26744798}, {'id': 'https://openalex.org/C2776134451', 'wikidata': 'https://www.wikidata.org/wiki/Q422244', 'display_name': 'Fluoxetine', 'level': 4, 'score': 0.23963195}, {'id': 'https://openalex.org/C513476851', 'wikidata': 'https://www.wikidata.org/wiki/Q170304', 'display_name': 'Dopamine', 'level': 2, 'score': 0.21289286}, {'id': 'https://openalex.org/C2781161787', 'wikidata': 'https://www.wikidata.org/wiki/Q48360', 'display_name': 'Hippocampus', 'level': 2, 'score': 0.0803923}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C2777843972', 'wikidata': 'https://www.wikidata.org/wiki/Q2462253', 'display_name': 'Smoking cessation', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fcvm.2021.704281', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fcvm.2021.704281/pdf', 'source': {'id': 'https://openalex.org/S2595413687', 'display_name': 'Frontiers in Cardiovascular Medicine', 'issn_l': '2297-055X', 'issn': ['2297-055X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/8b9505c9ce5046ceb32d1d7aeb6ff4ac', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/11392/2476221', 'pdf_url': 'https://sfera.unife.it/bitstream/11392/2476221/1/2021%20Calvi%20antidepressants%20blood%20pressure.pdf', 'source': {'id': 'https://openalex.org/S4306400369', 'display_name': 'Institutional Research Information System University of Ferrara (University of Ferrara)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I201324441', 'host_organization_name': 'University of Ferrara', 'host_organization_lineage': ['https://openalex.org/I201324441'], 'host_organization_lineage_names': ['University of Ferrara'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.frontiersin.org/articles/10.3389/fcvm.2021.704281/full', 'pdf_url': 'https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2021.704281/pdf', 'source': {'id': 'https://openalex.org/S4306400369', 'display_name': 'Institutional Research Information System University of Ferrara (University of Ferrara)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I201324441', 'host_organization_name': 'University of Ferrara', 'host_organization_lineage': ['https://openalex.org/I201324441'], 'host_organization_lineage_names': ['University of Ferrara'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370473', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34414219', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fcvm.2021.704281', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fcvm.2021.704281/pdf', 'source': {'id': 'https://openalex.org/S2595413687', 'display_name': 'Frontiers in Cardiovascular Medicine', 'issn_l': '2297-055X', 'issn': ['2297-055X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.86, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 242, 'referenced_works': ['https://openalex.org/W115158135', 'https://openalex.org/W1268568596', 'https://openalex.org/W131238900', 'https://openalex.org/W1499334104', 'https://openalex.org/W153453255', 'https://openalex.org/W1555183507', 'https://openalex.org/W1570836689', 'https://openalex.org/W1601176695', 'https://openalex.org/W1621882481', 'https://openalex.org/W1736508677', 'https://openalex.org/W1963888704', 'https://openalex.org/W1964022439', 'https://openalex.org/W1964372552', 'https://openalex.org/W1967621164', 'https://openalex.org/W1969125489', 'https://openalex.org/W1970541793', 'https://openalex.org/W1972638764', 'https://openalex.org/W1972715917', 'https://openalex.org/W1975656763', 'https://openalex.org/W1978084418', 'https://openalex.org/W1978163509', 'https://openalex.org/W1980873104', 'https://openalex.org/W1984871706', 'https://openalex.org/W1984933314', 'https://openalex.org/W1985215029', 'https://openalex.org/W1986224087', 'https://openalex.org/W1988010405', 'https://openalex.org/W1989302385', 'https://openalex.org/W1990038183', 'https://openalex.org/W1993588851', 'https://openalex.org/W1995472991', 'https://openalex.org/W1995552213', 'https://openalex.org/W1996889745', 'https://openalex.org/W2000472637', 'https://openalex.org/W2001359769', 'https://openalex.org/W2003179603', 'https://openalex.org/W2003782495', 'https://openalex.org/W2004657489', 'https://openalex.org/W2006526695', 'https://openalex.org/W2010968308', 'https://openalex.org/W2011768584', 'https://openalex.org/W2012902993', 'https://openalex.org/W2013454515', 'https://openalex.org/W2013652607', 'https://openalex.org/W2013997031', 'https://openalex.org/W2014099501', 'https://openalex.org/W2015411250', 'https://openalex.org/W2016961635', 'https://openalex.org/W2018099384', 'https://openalex.org/W2021196363', 'https://openalex.org/W2021468655', 'https://openalex.org/W2024678540', 'https://openalex.org/W2024858939', 'https://openalex.org/W2024994980', 'https://openalex.org/W2026068578', 'https://openalex.org/W2026410503', 'https://openalex.org/W2028022490', 'https://openalex.org/W2028210993', 'https://openalex.org/W2029846038', 'https://openalex.org/W2030219453', 'https://openalex.org/W2031270753', 'https://openalex.org/W2032112217', 'https://openalex.org/W2032335049', 'https://openalex.org/W2033750783', 'https://openalex.org/W2034032319', 'https://openalex.org/W2034488148', 'https://openalex.org/W2035421865', 'https://openalex.org/W2036117555', 'https://openalex.org/W2036137877', 'https://openalex.org/W2037833111', 'https://openalex.org/W2037968404', 'https://openalex.org/W2041475887', 'https://openalex.org/W2045332418', 'https://openalex.org/W2045551092', 'https://openalex.org/W2046128012', 'https://openalex.org/W2046655818', 'https://openalex.org/W2046777567', 'https://openalex.org/W2048276978', 'https://openalex.org/W2048340122', 'https://openalex.org/W2050887184', 'https://openalex.org/W2050943157', 'https://openalex.org/W2051023696', 'https://openalex.org/W2051442292', 'https://openalex.org/W2053706211', 'https://openalex.org/W2054083972', 'https://openalex.org/W2055816584', 'https://openalex.org/W2056800448', 'https://openalex.org/W2058837262', 'https://openalex.org/W2059502896', 'https://openalex.org/W2060782218', 'https://openalex.org/W2061731424', 'https://openalex.org/W2062173422', 'https://openalex.org/W2062969764', 'https://openalex.org/W2064231377', 'https://openalex.org/W2065532796', 'https://openalex.org/W2065876632', 'https://openalex.org/W2068269468', 'https://openalex.org/W2068497137', 'https://openalex.org/W2068512307', 'https://openalex.org/W2068602961', 'https://openalex.org/W2069523889', 'https://openalex.org/W2070119866', 'https://openalex.org/W2070851857', 'https://openalex.org/W2073060432', 'https://openalex.org/W2074133854', 'https://openalex.org/W2074335684', 'https://openalex.org/W2075066549', 'https://openalex.org/W2077205688', 'https://openalex.org/W2077685835', 'https://openalex.org/W2078107065', 'https://openalex.org/W2078627160', 'https://openalex.org/W2080027494', 'https://openalex.org/W2080993294', 'https://openalex.org/W2083014351', 'https://openalex.org/W2084168719', 'https://openalex.org/W2084844559', 'https://openalex.org/W2086193772', 'https://openalex.org/W2086467579', 'https://openalex.org/W2086920841', 'https://openalex.org/W2088015421', 'https://openalex.org/W2093142789', 'https://openalex.org/W2093728377', 'https://openalex.org/W2097633023', 'https://openalex.org/W2098697701', 'https://openalex.org/W2099141488', 'https://openalex.org/W2100945484', 'https://openalex.org/W2101083948', 'https://openalex.org/W2101818448', 'https://openalex.org/W2101820523', 'https://openalex.org/W2101978900', 'https://openalex.org/W2103629684', 'https://openalex.org/W2103959499', 'https://openalex.org/W2104101497', 'https://openalex.org/W2110321068', 'https://openalex.org/W2112697709', 'https://openalex.org/W2113237951', 'https://openalex.org/W2116763520', 'https://openalex.org/W2118004529', 'https://openalex.org/W2118111259', 'https://openalex.org/W2118171954', 'https://openalex.org/W2119176600', 'https://openalex.org/W2121404852', 'https://openalex.org/W2122427861', 'https://openalex.org/W2122583624', 'https://openalex.org/W2124758113', 'https://openalex.org/W2125205137', 'https://openalex.org/W2125553099', 'https://openalex.org/W2126095527', 'https://openalex.org/W2126462245', 'https://openalex.org/W2128127913', 'https://openalex.org/W2129478148', 'https://openalex.org/W2131610464', 'https://openalex.org/W2134918392', 'https://openalex.org/W2136168926', 'https://openalex.org/W2137977071', 'https://openalex.org/W2140848806', 'https://openalex.org/W2141625451', 'https://openalex.org/W2146569797', 'https://openalex.org/W2148136118', 'https://openalex.org/W2148158932', 'https://openalex.org/W2150054768', 'https://openalex.org/W2150331062', 'https://openalex.org/W2154248348', 'https://openalex.org/W2155959499', 'https://openalex.org/W2156288492', 'https://openalex.org/W2157536788', 'https://openalex.org/W2158152684', 'https://openalex.org/W2158176267', 'https://openalex.org/W2158245987', 'https://openalex.org/W2159601487', 'https://openalex.org/W2165807518', 'https://openalex.org/W2168999263', 'https://openalex.org/W2203984047', 'https://openalex.org/W2249451884', 'https://openalex.org/W2270496518', 'https://openalex.org/W2286488054', 'https://openalex.org/W2319421857', 'https://openalex.org/W2322391192', 'https://openalex.org/W2322790968', 'https://openalex.org/W2335754632', 'https://openalex.org/W2396356356', 'https://openalex.org/W2397665628', 'https://openalex.org/W2411013142', 'https://openalex.org/W2413104291', 'https://openalex.org/W2413808488', 'https://openalex.org/W2416548740', 'https://openalex.org/W2427238996', 'https://openalex.org/W2462482574', 'https://openalex.org/W2465053470', 'https://openalex.org/W2470249791', 'https://openalex.org/W2477696699', 'https://openalex.org/W2517571027', 'https://openalex.org/W2533950422', 'https://openalex.org/W2556801451', 'https://openalex.org/W2586564560', 'https://openalex.org/W2591995433', 'https://openalex.org/W2592096970', 'https://openalex.org/W2664858983', 'https://openalex.org/W2730900010', 'https://openalex.org/W2737990059', 'https://openalex.org/W2750800356', 'https://openalex.org/W2751884637', 'https://openalex.org/W2765684626', 'https://openalex.org/W2767041448', 'https://openalex.org/W2767504574', 'https://openalex.org/W2782645554', 'https://openalex.org/W2790615343', 'https://openalex.org/W2801269787', 'https://openalex.org/W2805657661', 'https://openalex.org/W2883361988', 'https://openalex.org/W2886002658', 'https://openalex.org/W2887678989', 'https://openalex.org/W2904390344', 'https://openalex.org/W2910200143', 'https://openalex.org/W2912654919', 'https://openalex.org/W2912703574', 'https://openalex.org/W2913339094', 'https://openalex.org/W2921998603', 'https://openalex.org/W2935996570', 'https://openalex.org/W2941618972', 'https://openalex.org/W2947858251', 'https://openalex.org/W2962016589', 'https://openalex.org/W2964530771', 'https://openalex.org/W2964919741', 'https://openalex.org/W2981856767', 'https://openalex.org/W3001463472', 'https://openalex.org/W3003357216', 'https://openalex.org/W3009526312', 'https://openalex.org/W3040543827', 'https://openalex.org/W3080791429', 'https://openalex.org/W3081128495', 'https://openalex.org/W3092842649', 'https://openalex.org/W3110981746', 'https://openalex.org/W3128158370', 'https://openalex.org/W34624693', 'https://openalex.org/W4234092905', 'https://openalex.org/W4245248461', 'https://openalex.org/W4246132639', 'https://openalex.org/W4247280611', 'https://openalex.org/W4253975533', 'https://openalex.org/W4300588952', 'https://openalex.org/W77213692'], 'related_works': ['https://openalex.org/W4400779921', 'https://openalex.org/W4250276478', 'https://openalex.org/W4248546441', 'https://openalex.org/W4245739203', 'https://openalex.org/W2498264575', 'https://openalex.org/W2371573973', 'https://openalex.org/W2323437214', 'https://openalex.org/W2084020613', 'https://openalex.org/W2008327202', 'https://openalex.org/W1984777324'], 'abstract_inverted_index': {'Individuals': [0], 'suffering': [1], 'from': [2], 'depressive': [3, 307], 'disorders': [4], 'display': [5], 'a': [6, 89, 112, 134, 284, 292], 'greater': [7, 113, 120], 'incidence': [8], 'of': [9, 18, 36, 69, 115, 138, 277, 294, 320, 323], 'hypertension': [10], 'compared': [11], 'with': [12, 181, 211, 220, 243, 266, 271, 333], 'the': [13, 19, 34, 67, 98, 123, 212, 225, 295, 321], 'general': [14], 'population,': [15], 'despite': [16], 'reports': [17], 'association': [20], 'between': [21], 'depression': [22], 'and': [23, 49, 58, 88, 103, 152, 188, 203, 216, 222, 302, 316, 330], 'hypotension.': [24], 'This': [25, 61], 'phenomenon': [26], 'may': [27, 40, 173, 197, 230, 287], 'depend,': [28], 'at': [29, 169], 'least': [30], 'in': [31, 145, 179, 245], 'part,': [32], 'on': [33, 47, 55, 66, 72, 84, 92, 122, 142, 193, 235, 326], 'use': [35], 'antidepressant': [37, 70, 228, 289, 324], 'drugs,': [38], 'which': [39], 'influence': [41], 'blood': [42, 73, 93, 143, 165, 194, 236, 246, 313, 327], 'pressure': [43, 144, 166, 195, 314, 328], 'through': [44], 'different': [45], 'effects': [46, 83, 121, 141, 154, 192, 207, 234, 322], 'adrenergic': [48], 'serotoninergic': [50], 'pathways,': [51], 'as': [52, 54, 248, 250, 291], 'well': [53, 249], 'histaminergic,': [56], 'dopaminergic,': [57], 'cholinergic': [59], 'systems.': [60], 'review': [62], 'summarizes': [63], 'extant': [64], 'literature': [65], 'effect': [68], 'drugs': [71, 325], 'pressure.': [74, 94, 237], 'Selective': [75], 'serotonin': [76, 296], 'reuptake': [77, 107, 129, 159], 'inhibitors': [78], 'are': [79, 155, 208], 'characterized': [80], 'by': [81], 'limited': [82, 233], 'autonomic': [85, 303], 'system': [86], 'activity': [87], 'lower': [90], 'impact': [91], 'Thus,': [95], 'they': [96], 'represent': [97], 'safest': [99], 'class-particularly': [100], 'among': [101], 'elderly': [102], 'cardiovascular': [104, 182, 317], 'patients.': [105], 'Serotonin-norepinephrine': [106], 'inhibitors,': [108, 257], 'particularly': [109, 253], 'venlafaxine,': [110], 'carry': [111], 'risk': [114], 'hypertension,': [116], 'possibly': [117], 'related': [118], 'to': [119, 164, 200, 275], 'sympathetic': [124], 'nervous': [125], 'system.': [126], 'The': [127, 157, 184], 'norepinephrine': [128], 'inhibitor': [130, 160], 'reboxetine': [131], 'is': [132], 'considered': [133], 'safe': [135], 'option': [136], 'because': [137, 319], 'its': [139], 'neutral': [140], 'long-term': [146], 'studies,': [147], 'even': [148], 'if': [149], 'both': [150], 'hypotensive': [151], 'hypertensive': [153, 272, 285], 'reported.': [156], 'dopamine-norepinephrine': [158], 'bupropion': [161], 'can': [162], 'lead': [163, 199], 'increases,': [167], 'usually': [168], 'high': [170], 'doses,': [171], 'but': [172, 196, 218], 'also': [174, 209, 231, 298], 'cause': [175], 'orthostatic': [176, 201, 251, 267], 'hypotension,': [177, 252], 'especially': [178], 'patients': [180, 308], 'diseases.': [183], 'norepinephrine-serotonin': [185], 'modulators,': [186, 214], 'mirtazapine': [187], 'mianserin,': [189], 'have': [190, 232, 240, 263], 'minimal': [191], 'rarely': [198], 'hypotension': [202, 268], 'falls.': [204], 'These': [205], 'adverse': [206], 'observed': [210], 'serotonin-reuptake': [213], 'nefazodone': [215], 'trazodone,': [217], 'seldomly': [219], 'vortioxetine': [221], 'vilazodone.': [223], 'Agomelatine,': [224], 'only': [226], 'melatonergic': [227], 'drug,': [229], 'Tricyclic': [238], 'antidepressants': [239], 'been': [241, 264], 'associated': [242, 265], 'increases': [244], 'pressure,': [247], 'imipramine.': [254], 'Oral': [255], 'monoamine-oxidase': [256], 'less': [258], 'frequently': [259], 'skin': [260], 'patch': [261], 'formulations,': [262], 'or,': [269], 'conversely,': [270], 'crisis': [273, 286], 'due': [274], 'ingestion': [276], 'tyramine-containing': [278], 'food': [279], '(i.e.,': [280], 'cheese': [281], 'reaction).': [282], 'Lastly,': [283], 'complicate': [288], 'treatment': [290], 'part': [293], 'syndrome,': [297], 'including': [299], 'neuromuscular,': [300], 'cognitive,': [301], 'dysfunctions.': [304], 'Clinicians': [305], 'treating': [306], 'should': [309], 'carefully': [310], 'consider': [311], 'their': [312], 'status': [315], 'comorbidities': [318], 'profiles': [329], 'potential': [331], 'interactions': [332], 'antihypertensive': [334], 'treatments.': [335]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3190446843', 'counts_by_year': [{'year': 2024, 'cited_by_count': 30}, {'year': 2023, 'cited_by_count': 24}, {'year': 2022, 'cited_by_count': 10}], 'updated_date': '2024-12-31T14:24:36.439408', 'created_date': '2021-08-16'}