Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3185580019', 'doi': 'https://doi.org/10.3390/ijerph18157806', 'title': 'Oxidative Stress in Non-Dialysis-Dependent Chronic Kidney Disease Patients', 'display_name': 'Oxidative Stress in Non-Dialysis-Dependent Chronic Kidney Disease Patients', 'publication_year': 2021, 'publication_date': '2021-07-23', 'ids': {'openalex': 'https://openalex.org/W3185580019', 'doi': 'https://doi.org/10.3390/ijerph18157806', 'mag': '3185580019', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34360098', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8345537'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijerph18157806', 'pdf_url': 'https://www.mdpi.com/1660-4601/18/15/7806/pdf?version=1627019830', 'source': {'id': 'https://openalex.org/S15239247', 'display_name': 'International Journal of Environmental Research and Public Health', 'issn_l': '1660-4601', 'issn': ['1660-4601', '1661-7827'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/1660-4601/18/15/7806/pdf?version=1627019830', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019851536', 'display_name': 'Patricia Tomás-Simó', 'orcid': 'https://orcid.org/0000-0001-7659-611X'}, 'institutions': [{'id': 'https://openalex.org/I4210094406', 'display_name': 'Hospital Clínico Universitario de Valencia', 'ror': 'https://ror.org/00hpnj894', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094406']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Patricia Tomás-Simó', 'raw_affiliation_strings': ['Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210094406', 'https://openalex.org/I16097986']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090919713', 'display_name': 'Luis D’Marco', 'orcid': 'https://orcid.org/0000-0003-0148-891X'}, 'institutions': [{'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}, {'id': 'https://openalex.org/I4210094406', 'display_name': 'Hospital Clínico Universitario de Valencia', 'ror': 'https://ror.org/00hpnj894', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094406']}], 'countries': ['ES'], 'is_corresponding': True, 'raw_author_name': 'Luis D’Marco', 'raw_affiliation_strings': ['Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I16097986', 'https://openalex.org/I4210094406']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077576695', 'display_name': 'María Romero-Parra', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210094406', 'display_name': 'Hospital Clínico Universitario de Valencia', 'ror': 'https://ror.org/00hpnj894', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094406']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'María Romero-Parra', 'raw_affiliation_strings': ['Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210094406', 'https://openalex.org/I16097986']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088291827', 'display_name': 'Mari Carmen Tormos-Muñoz', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210126200', 'display_name': 'Hospital Universitario Doctor Peset', 'ror': 'https://ror.org/03971n288', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126200']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}, {'id': 'https://openalex.org/I4210097149', 'display_name': 'Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana', 'ror': 'https://ror.org/0116vew40', 'country_code': 'ES', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210097149']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Mari Carmen Tormos-Muñoz', 'raw_affiliation_strings': ['Service of Clinical Analysis, Department of Biochemistry and Molecular Biology, Facultad de Medicina y Odontología-INCLIVA, Hospital Universitario Dr. Peset, FISABIO, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Service of Clinical Analysis, Department of Biochemistry and Molecular Biology, Facultad de Medicina y Odontología-INCLIVA, Hospital Universitario Dr. Peset, FISABIO, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210126200', 'https://openalex.org/I16097986', 'https://openalex.org/I4210097149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056063238', 'display_name': 'Guillermo T. Sáez', 'orcid': 'https://orcid.org/0000-0002-8164-4048'}, 'institutions': [{'id': 'https://openalex.org/I4210126200', 'display_name': 'Hospital Universitario Doctor Peset', 'ror': 'https://ror.org/03971n288', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126200']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}, {'id': 'https://openalex.org/I4210097149', 'display_name': 'Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana', 'ror': 'https://ror.org/0116vew40', 'country_code': 'ES', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210097149']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Guillermo Sáez', 'raw_affiliation_strings': ['Service of Clinical Analysis, Department of Biochemistry and Molecular Biology, Facultad de Medicina y Odontología-INCLIVA, Hospital Universitario Dr. Peset, FISABIO, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Service of Clinical Analysis, Department of Biochemistry and Molecular Biology, Facultad de Medicina y Odontología-INCLIVA, Hospital Universitario Dr. Peset, FISABIO, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210126200', 'https://openalex.org/I16097986', 'https://openalex.org/I4210097149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047053376', 'display_name': 'Isidro Torregrosa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210094406', 'display_name': 'Hospital Clínico Universitario de Valencia', 'ror': 'https://ror.org/00hpnj894', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094406']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Isidro Torregrosa', 'raw_affiliation_strings': ['Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210094406', 'https://openalex.org/I16097986']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030405404', 'display_name': 'Nuria Estañ-Capell', 'orcid': 'https://orcid.org/0000-0001-8768-3139'}, 'institutions': [{'id': 'https://openalex.org/I4210126200', 'display_name': 'Hospital Universitario Doctor Peset', 'ror': 'https://ror.org/03971n288', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210126200']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}, {'id': 'https://openalex.org/I4210097149', 'display_name': 'Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana', 'ror': 'https://ror.org/0116vew40', 'country_code': 'ES', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210097149']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Nuria Estañ-Capell', 'raw_affiliation_strings': ['Service of Clinical Analysis, Department of Biochemistry and Molecular Biology, Facultad de Medicina y Odontología-INCLIVA, Hospital Universitario Dr. Peset, FISABIO, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Service of Clinical Analysis, Department of Biochemistry and Molecular Biology, Facultad de Medicina y Odontología-INCLIVA, Hospital Universitario Dr. Peset, FISABIO, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210126200', 'https://openalex.org/I16097986', 'https://openalex.org/I4210097149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007266654', 'display_name': 'Alfonso Miguel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210094406', 'display_name': 'Hospital Clínico Universitario de Valencia', 'ror': 'https://ror.org/00hpnj894', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094406']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Alfonso Miguel', 'raw_affiliation_strings': ['Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210094406', 'https://openalex.org/I16097986']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046692355', 'display_name': 'José Luis Górriz', 'orcid': 'https://orcid.org/0000-0002-1134-9051'}, 'institutions': [{'id': 'https://openalex.org/I4210094406', 'display_name': 'Hospital Clínico Universitario de Valencia', 'ror': 'https://ror.org/00hpnj894', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094406']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'José Luis Gorriz', 'raw_affiliation_strings': ['Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210094406', 'https://openalex.org/I16097986']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5047440765', 'display_name': 'María Jesús Puchades', 'orcid': 'https://orcid.org/0000-0001-6927-071X'}, 'institutions': [{'id': 'https://openalex.org/I4210094406', 'display_name': 'Hospital Clínico Universitario de Valencia', 'ror': 'https://ror.org/00hpnj894', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210094406']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}], 'countries': ['ES'], 'is_corresponding': True, 'raw_author_name': 'María Jesús Puchades', 'raw_affiliation_strings': ['Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Nephrology Department, Hospital Clínico Universitario, INCLIVA, Universidad de Valencia, 46010 Valencia, Spain', 'institution_ids': ['https://openalex.org/I4210094406', 'https://openalex.org/I16097986']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5090919713', 'https://openalex.org/A5047440765'], 'corresponding_institution_ids': ['https://openalex.org/I16097986', 'https://openalex.org/I4210094406', 'https://openalex.org/I4210094406', 'https://openalex.org/I16097986'], 'apc_list': {'value': 2500, 'currency': 'CHF', 'value_usd': 2707, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'CHF', 'value_usd': 2707, 'provenance': 'doaj'}, 'fwci': 1.607, 'has_fulltext': False, 'cited_by_count': 12, 'citation_normalized_percentile': {'value': 0.724454, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '18', 'issue': '15', 'first_page': '7806', 'last_page': '7806'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11481', 'display_name': 'Redox Environment and Cellular Metabolism', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11481', 'display_name': 'Redox Environment and Cellular Metabolism', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10499', 'display_name': 'Role of Homocysteine in Health and Disease', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10277', 'display_name': 'Vitamin D and Health Outcomes', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/malondialdehyde', 'display_name': 'Malondialdehyde', 'score': 0.6092429}, {'id': 'https://openalex.org/keywords/oxidative-stress', 'display_name': 'Oxidative Stress', 'score': 0.549144}], 'concepts': [{'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.8973403}, {'id': 'https://openalex.org/C2778653478', 'wikidata': 'https://www.wikidata.org/wiki/Q1054718', 'display_name': 'Kidney disease', 'level': 2, 'score': 0.789128}, {'id': 'https://openalex.org/C2779978075', 'wikidata': 'https://www.wikidata.org/wiki/Q202301', 'display_name': 'Dialysis', 'level': 2, 'score': 0.6404468}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.639401}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6393262}, {'id': 'https://openalex.org/C538909803', 'wikidata': 'https://www.wikidata.org/wiki/Q116907', 'display_name': 'Glutathione', 'level': 3, 'score': 0.63285244}, {'id': 'https://openalex.org/C2778401633', 'wikidata': 'https://www.wikidata.org/wiki/Q418661', 'display_name': 'Malondialdehyde', 'level': 3, 'score': 0.6092429}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.4935459}, {'id': 'https://openalex.org/C159641895', 'wikidata': 'https://www.wikidata.org/wiki/Q108377937', 'display_name': 'Renal function', 'level': 2, 'score': 0.4834755}, {'id': 'https://openalex.org/C2778004101', 'wikidata': 'https://www.wikidata.org/wiki/Q133948', 'display_name': 'Antioxidant', 'level': 2, 'score': 0.41241577}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.41043156}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.19563806}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.17020473}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D051436', 'descriptor_name': 'Renal Insufficiency, Chronic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000080242', 'descriptor_name': "8-Hydroxy-2'-Deoxyguanosine", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002908', 'descriptor_name': 'Chronic Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008315', 'descriptor_name': 'Malondialdehyde', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010084', 'descriptor_name': 'Oxidation-Reduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijerph18157806', 'pdf_url': 'https://www.mdpi.com/1660-4601/18/15/7806/pdf?version=1627019830', 'source': {'id': 'https://openalex.org/S15239247', 'display_name': 'International Journal of Environmental Research and Public Health', 'issn_l': '1660-4601', 'issn': ['1660-4601', '1661-7827'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345537', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34360098', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijerph18157806', 'pdf_url': 'https://www.mdpi.com/1660-4601/18/15/7806/pdf?version=1627019830', 'source': {'id': 'https://openalex.org/S15239247', 'display_name': 'International Journal of Environmental Research and Public Health', 'issn_l': '1660-4601', 'issn': ['1660-4601', '1661-7827'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Zero hunger', 'score': 0.74, 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 48, 'referenced_works': ['https://openalex.org/W1178646482', 'https://openalex.org/W1481144095', 'https://openalex.org/W1485087964', 'https://openalex.org/W1558823847', 'https://openalex.org/W1591054099', 'https://openalex.org/W1699432502', 'https://openalex.org/W1963611077', 'https://openalex.org/W1967264164', 'https://openalex.org/W1967345257', 'https://openalex.org/W1987613563', 'https://openalex.org/W1991473373', 'https://openalex.org/W1992668261', 'https://openalex.org/W1993360039', 'https://openalex.org/W1997265694', 'https://openalex.org/W2003521419', 'https://openalex.org/W2009451984', 'https://openalex.org/W2010290489', 'https://openalex.org/W2019369653', 'https://openalex.org/W2043912977', 'https://openalex.org/W2056621811', 'https://openalex.org/W2057114546', 'https://openalex.org/W2074207584', 'https://openalex.org/W2076496127', 'https://openalex.org/W2084503441', 'https://openalex.org/W2104906781', 'https://openalex.org/W2107919301', 'https://openalex.org/W2109977819', 'https://openalex.org/W2110171483', 'https://openalex.org/W2113760558', 'https://openalex.org/W2114164409', 'https://openalex.org/W2121061355', 'https://openalex.org/W2123870041', 'https://openalex.org/W2155729476', 'https://openalex.org/W2162055087', 'https://openalex.org/W21693991', 'https://openalex.org/W2327065719', 'https://openalex.org/W2514849591', 'https://openalex.org/W2751635377', 'https://openalex.org/W2769355553', 'https://openalex.org/W2791312568', 'https://openalex.org/W2956038375', 'https://openalex.org/W2963408498', 'https://openalex.org/W2964979089', 'https://openalex.org/W2972545838', 'https://openalex.org/W2973291426', 'https://openalex.org/W2989774063', 'https://openalex.org/W3003972077', 'https://openalex.org/W3015615582'], 'related_works': ['https://openalex.org/W4320929188', 'https://openalex.org/W3096935520', 'https://openalex.org/W2954638309', 'https://openalex.org/W2602111502', 'https://openalex.org/W2314286400', 'https://openalex.org/W2091429609', 'https://openalex.org/W2066852536', 'https://openalex.org/W1971368128', 'https://openalex.org/W188720285', 'https://openalex.org/W125774832'], 'abstract_inverted_index': {'Background:': [0], 'Cardiovascular': [1], 'complications': [2], 'are': [3], 'the': [4, 20, 41, 101, 140, 165, 175, 216], 'leading': [5], 'cause': [6], 'of': [7, 14, 23, 44, 120, 159, 168, 174, 190, 197], 'morbidity': [8], 'and': [9, 48, 58, 73, 78, 92, 110, 122, 139, 145, 152, 230], 'mortality': [10, 25], 'at': [11, 40, 117], 'any': [12], 'stage': [13], 'chronic': [15], 'kidney': [16, 201], 'disease': [17, 94], '(CKD).': [18], 'Moreover,': [19], 'high': [21], 'rate': [22], 'cardiovascular': [24, 59, 93], 'observed': [26, 180], 'in': [27, 82, 95, 104, 113, 211, 215, 252], 'these': [28, 231], 'patients': [29, 116, 213, 221], 'is': [30, 246], 'associated': [31], 'with': [32, 194], 'an': [33], 'accelerated': [34], 'atherosclerosis': [35], 'process': [36, 103], 'that': [37], 'likely': [38], 'starts': [39], 'early': [42, 166], 'stages': [43, 119, 167], 'CKD.': [45], 'Thus,': [46, 243], 'traditional': [47], 'non-traditional': [49], 'or': [50], 'uremic-related': [51], 'factors': [52], 'represent': [53], 'a': [54, 181, 187], 'link': [55], 'between': [56, 89, 240], 'CKD': [57, 121, 169, 212, 220, 241], 'risk.': [60], 'Among': [61], 'non-conventional': [62], 'risk': [63], 'factors,': [64], 'particular': [65], 'focus': [66], 'has': [67], 'been': [68, 87], 'placed': [69], 'on': [70], 'anaemia,': [71], 'mineral': [72], 'bone': [74], 'disorders,': [75], 'inflammation,': [76], 'malnutrition': [77], 'oxidative': [79, 90, 128, 160, 183, 205, 225], 'stress': [80, 91, 129, 161, 226], 'and,': [81], 'this': [83, 253], 'regard,': [84], 'connections': [85], 'have': [86], 'reported': [88], 'dialysis': [96], 'patients.': [97], 'Methods:': [98], 'We': [99, 179], 'evaluated': [100], 'oxidation': [102, 147], 'different': [105, 118], 'molecular': [106, 176], 'lines': [107, 177], '(proteins,': [108], 'lipids': [109], 'genetic': [111], 'material)': [112], '155': [114], 'non-dialysis': [115], '45': [123], 'healthy': [124, 228], 'controls.': [125], 'To': [126], 'assess': [127], 'status,': [130], 'we': [131], 'analyzed': [132], 'oxidized': [133, 191], 'glutathione': [134, 137, 142], '(GSSG),': [135], 'reduced': [136], '(GSH)': [138], 'oxidized/reduced': [141], 'ratio': [143], '(GSSG/GSH)': [144], 'other': [146], 'indicators,': [148], 'including': [149], 'malondialdehyde': [150], '(MDA)': [151], '8-oxo-2’-deoxyguanosine': [153], '(8-oxo-dG).': [154], 'Results:': [155], 'An': [156], 'active': [157], 'grade': [158], 'was': [162], 'found': [163], 'from': [164], 'onwards,': [170], 'which': [171], 'affected': [172], 'all': [173], 'studied.': [178], 'heightened': [182], 'state': [184], '(indicated': [185], 'by': [186], 'higher': [188, 224], 'level': [189], 'molecules': [192], 'together': [193], 'decreased': [195], 'levels': [196], 'antioxidant': [198], 'molecules)': [199], 'as': [200, 234], 'function': [202], 'declined.': [203], 'Furthermore,': [204], 'stress-related': [206], 'alterations': [207, 232], 'were': [208], 'significantly': [209, 223], 'greater': [210], 'than': [214, 227], 'control': [217], 'group.': [218], 'Conclusions:': [219], 'exhibit': [222], 'individuals,': [229], 'intensify': [233], 'eGFR': [235], 'declines,': [236], 'showing': [237], 'significant': [238], 'differences': [239], 'stages.': [242], 'future': [244], 'research': [245], 'warranted': [247], 'to': [248], 'provide': [249], 'clearer': [250], 'results': [251], 'area.': [254]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3185580019', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 3}], 'updated_date': '2024-08-15T08:36:14.498734', 'created_date': '2021-08-02'}