Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3185130928', 'doi': 'https://doi.org/10.1038/s41589-021-00836-0', 'title': 'Metabolic engineering strategies to enable microbial utilization of C1 feedstocks', 'display_name': 'Metabolic engineering strategies to enable microbial utilization of C1 feedstocks', 'publication_year': 2021, 'publication_date': '2021-07-26', 'ids': {'openalex': 'https://openalex.org/W3185130928', 'doi': 'https://doi.org/10.1038/s41589-021-00836-0', 'mag': '3185130928', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34312558'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/s41589-021-00836-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S51309854', 'display_name': 'Nature Chemical Biology', 'issn_l': '1552-4450', 'issn': ['1552-4450', '1552-4469'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'http://hdl.handle.net/10044/1/96219', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5052344563', 'display_name': 'Wei Jiang', 'orcid': 'https://orcid.org/0000-0002-1374-053X'}, 'institutions': [{'id': 'https://openalex.org/I47508984', 'display_name': 'Imperial College London', 'ror': 'https://ror.org/041kmwe10', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I47508984']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Wei Jiang', 'raw_affiliation_strings': ['Imperial College Centre for Synthetic Biology, Imperial College London, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Imperial College Centre for Synthetic Biology, Imperial College London, London, UK', 'institution_ids': ['https://openalex.org/I47508984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003460466', 'display_name': 'David Hernández-Villamor', 'orcid': 'https://orcid.org/0000-0002-9055-4431'}, 'institutions': [{'id': 'https://openalex.org/I47508984', 'display_name': 'Imperial College London', 'ror': 'https://ror.org/041kmwe10', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I47508984']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'David Hernández Villamor', 'raw_affiliation_strings': ['Imperial College Centre for Synthetic Biology, Imperial College London, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Imperial College Centre for Synthetic Biology, Imperial College London, London, UK', 'institution_ids': ['https://openalex.org/I47508984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068916001', 'display_name': 'Huadong Peng', 'orcid': 'https://orcid.org/0000-0003-0635-0493'}, 'institutions': [{'id': 'https://openalex.org/I47508984', 'display_name': 'Imperial College London', 'ror': 'https://ror.org/041kmwe10', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I47508984']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Huadong Peng', 'raw_affiliation_strings': ['Imperial College Centre for Synthetic Biology, Imperial College London, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Imperial College Centre for Synthetic Biology, Imperial College London, London, UK', 'institution_ids': ['https://openalex.org/I47508984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101740721', 'display_name': 'Jian Chen', 'orcid': 'https://orcid.org/0000-0003-3217-3224'}, 'institutions': [{'id': 'https://openalex.org/I111599522', 'display_name': 'Jiangnan University', 'ror': 'https://ror.org/04mkzax54', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I111599522']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jian Chen', 'raw_affiliation_strings': ['Key Laboratory of Carbohydrate Chemistry and Biotechnology, and Key Laboratory of industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Carbohydrate Chemistry and Biotechnology, and Key Laboratory of industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China', 'institution_ids': ['https://openalex.org/I111599522']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100348292', 'display_name': 'Long Liu', 'orcid': 'https://orcid.org/0000-0002-9679-9130'}, 'institutions': [{'id': 'https://openalex.org/I111599522', 'display_name': 'Jiangnan University', 'ror': 'https://ror.org/04mkzax54', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I111599522']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Long Liu', 'raw_affiliation_strings': ['Key Laboratory of Carbohydrate Chemistry and Biotechnology, and Key Laboratory of industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Carbohydrate Chemistry and Biotechnology, and Key Laboratory of industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China', 'institution_ids': ['https://openalex.org/I111599522']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078336817', 'display_name': 'Victoria S. Haritos', 'orcid': 'https://orcid.org/0000-0003-4630-9647'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Victoria Haritos', 'raw_affiliation_strings': ['Department of Chemical Engineering, Monash University, Clayton, Victoria, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemical Engineering, Monash University, Clayton, Victoria, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5065461384', 'display_name': 'Rodrigo Ledesma‐Amaro', 'orcid': 'https://orcid.org/0000-0003-2631-5898'}, 'institutions': [{'id': 'https://openalex.org/I47508984', 'display_name': 'Imperial College London', 'ror': 'https://ror.org/041kmwe10', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I47508984']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Rodrigo Ledesma-Amaro', 'raw_affiliation_strings': ['Department of Bioengineering, Imperial College London, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Department of Bioengineering, Imperial College London, London, UK', 'institution_ids': ['https://openalex.org/I47508984']}]}], 'countries_distinct_count': 3, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 9750, 'currency': 'EUR', 'value_usd': 11690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.114, 'has_fulltext': False, 'cited_by_count': 99, 'citation_normalized_percentile': {'value': 0.999791, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '17', 'issue': '8', 'first_page': '845', 'last_page': '855'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10932', 'display_name': 'Metabolic Engineering and Synthetic Biology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10932', 'display_name': 'Metabolic Engineering and Synthetic Biology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12688', 'display_name': 'Biological Methane Utilization and Metabolism', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10171', 'display_name': 'Technologies for Biofuel Production from Biomass', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/biomanufacturing', 'display_name': 'Biomanufacturing', 'score': 0.93444717}, {'id': 'https://openalex.org/keywords/synthetic-biology', 'display_name': 'Synthetic biology', 'score': 0.7986139}, {'id': 'https://openalex.org/keywords/metabolic-engineering', 'display_name': 'Metabolic Engineering', 'score': 0.555805}, {'id': 'https://openalex.org/keywords/formate-dehydrogenase', 'display_name': 'Formate dehydrogenase', 'score': 0.53669256}, {'id': 'https://openalex.org/keywords/microbial-metabolism', 'display_name': 'Microbial Metabolism', 'score': 0.534527}, {'id': 'https://openalex.org/keywords/industrial-biotechnology', 'display_name': 'Industrial biotechnology', 'score': 0.4866115}, {'id': 'https://openalex.org/keywords/industrial-microbiology', 'display_name': 'Industrial microbiology', 'score': 0.45938164}, {'id': 'https://openalex.org/keywords/heterologous', 'display_name': 'Heterologous', 'score': 0.42280787}], 'concepts': [{'id': 'https://openalex.org/C2775893736', 'wikidata': 'https://www.wikidata.org/wiki/Q25324110', 'display_name': 'Biomanufacturing', 'level': 2, 'score': 0.93444717}, {'id': 'https://openalex.org/C6350086', 'wikidata': 'https://www.wikidata.org/wiki/Q6822347', 'display_name': 'Metabolic engineering', 'level': 3, 'score': 0.8240683}, {'id': 'https://openalex.org/C191908910', 'wikidata': 'https://www.wikidata.org/wiki/Q862838', 'display_name': 'Synthetic biology', 'level': 2, 'score': 0.7986139}, {'id': 'https://openalex.org/C183696295', 'wikidata': 'https://www.wikidata.org/wiki/Q2487696', 'display_name': 'Biochemical engineering', 'level': 1, 'score': 0.6067406}, {'id': 'https://openalex.org/C2778428456', 'wikidata': 'https://www.wikidata.org/wiki/Q1147563', 'display_name': 'Formate dehydrogenase', 'level': 4, 'score': 0.53669256}, {'id': 'https://openalex.org/C2991947430', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Industrial biotechnology', 'level': 2, 'score': 0.4866115}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.46181026}, {'id': 'https://openalex.org/C2779039970', 'wikidata': 'https://www.wikidata.org/wiki/Q3610387', 'display_name': 'Industrial microbiology', 'level': 3, 'score': 0.45938164}, {'id': 'https://openalex.org/C152662350', 'wikidata': 'https://www.wikidata.org/wiki/Q815297', 'display_name': 'Systems biology', 'level': 2, 'score': 0.43663707}, {'id': 'https://openalex.org/C2780115692', 'wikidata': 'https://www.wikidata.org/wiki/Q5747302', 'display_name': 'Heterologous', 'level': 3, 'score': 0.42280787}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.35763788}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.30734766}, {'id': 'https://openalex.org/C2780178953', 'wikidata': 'https://www.wikidata.org/wiki/Q2001841', 'display_name': 'Formate', 'level': 3, 'score': 0.2460191}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.13468128}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.117544085}, {'id': 'https://openalex.org/C100544194', 'wikidata': 'https://www.wikidata.org/wiki/Q41760', 'display_name': 'Fermentation', 'level': 2, 'score': 0.07579079}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.07538727}, {'id': 'https://openalex.org/C161790260', 'wikidata': 'https://www.wikidata.org/wiki/Q82264', 'display_name': 'Catalysis', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001419', 'descriptor_name': 'Bacteria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005658', 'descriptor_name': 'Fungi', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D060847', 'descriptor_name': 'Metabolic Engineering', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001419', 'descriptor_name': 'Bacteria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001419', 'descriptor_name': 'Bacteria', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D002245', 'descriptor_name': 'Carbon Dioxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002245', 'descriptor_name': 'Carbon Dioxide', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002248', 'descriptor_name': 'Carbon Monoxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002248', 'descriptor_name': 'Carbon Monoxide', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005561', 'descriptor_name': 'Formates', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005561', 'descriptor_name': 'Formates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005658', 'descriptor_name': 'Fungi', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D005658', 'descriptor_name': 'Fungi', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008697', 'descriptor_name': 'Methane', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008697', 'descriptor_name': 'Methane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000432', 'descriptor_name': 'Methanol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000432', 'descriptor_name': 'Methanol', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/s41589-021-00836-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S51309854', 'display_name': 'Nature Chemical Biology', 'issn_l': '1552-4450', 'issn': ['1552-4450', '1552-4469'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10044/1/96219', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401396', 'display_name': 'Spiral (Imperial College London)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I47508984', 'host_organization_name': 'Imperial College London', 'host_organization_lineage': ['https://openalex.org/I47508984'], 'host_organization_lineage_names': ['Imperial College London'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34312558', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10044/1/96219', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401396', 'display_name': 'Spiral (Imperial College London)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I47508984', 'host_organization_name': 'Imperial College London', 'host_organization_lineage': ['https://openalex.org/I47508984'], 'host_organization_lineage_names': ['Imperial College London'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/9', 'score': 0.55, 'display_name': 'Industry, innovation and infrastructure'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 121, 'referenced_works': ['https://openalex.org/W1504489733', 'https://openalex.org/W1556517310', 'https://openalex.org/W1593839182', 'https://openalex.org/W1919881113', 'https://openalex.org/W1955127072', 'https://openalex.org/W1965481248', 'https://openalex.org/W1974252038', 'https://openalex.org/W1979081699', 'https://openalex.org/W1980731880', 'https://openalex.org/W1981673913', 'https://openalex.org/W1983999334', 'https://openalex.org/W1986606322', 'https://openalex.org/W1988585005', 'https://openalex.org/W1991242334', 'https://openalex.org/W1996982247', 'https://openalex.org/W2007544195', 'https://openalex.org/W2007853420', 'https://openalex.org/W2008681679', 'https://openalex.org/W2010713127', 'https://openalex.org/W2022642835', 'https://openalex.org/W2025962789', 'https://openalex.org/W2038872285', 'https://openalex.org/W2045296461', 'https://openalex.org/W2048610294', 'https://openalex.org/W2049869785', 'https://openalex.org/W2052696846', 'https://openalex.org/W2054222007', 'https://openalex.org/W2055190826', 'https://openalex.org/W2061939602', 'https://openalex.org/W2063112093', 'https://openalex.org/W2074023228', 'https://openalex.org/W2076336907', 'https://openalex.org/W2077274817', 'https://openalex.org/W2078383484', 'https://openalex.org/W2079114878', 'https://openalex.org/W2082905721', 'https://openalex.org/W2084333783', 'https://openalex.org/W2084739896', 'https://openalex.org/W2087721137', 'https://openalex.org/W2089641079', 'https://openalex.org/W2095668363', 'https://openalex.org/W2097930656', 'https://openalex.org/W2128836283', 'https://openalex.org/W2128898932', 'https://openalex.org/W2130107304', 'https://openalex.org/W2160657983', 'https://openalex.org/W2162169386', 'https://openalex.org/W2175095214', 'https://openalex.org/W2212924810', 'https://openalex.org/W2280940208', 'https://openalex.org/W2322101771', 'https://openalex.org/W2334153060', 'https://openalex.org/W2334504062', 'https://openalex.org/W2398525810', 'https://openalex.org/W2402509024', 'https://openalex.org/W2402686077', 'https://openalex.org/W2409222833', 'https://openalex.org/W2410886213', 'https://openalex.org/W2411247109', 'https://openalex.org/W2412234405', 'https://openalex.org/W2412929115', 'https://openalex.org/W2413764335', 'https://openalex.org/W2416216556', 'https://openalex.org/W2417025411', 'https://openalex.org/W2462891057', 'https://openalex.org/W2465167402', 'https://openalex.org/W2466165797', 'https://openalex.org/W2468352349', 'https://openalex.org/W2475550688', 'https://openalex.org/W2500482073', 'https://openalex.org/W2503176236', 'https://openalex.org/W2528667662', 'https://openalex.org/W2536714764', 'https://openalex.org/W2545445171', 'https://openalex.org/W2547048665', 'https://openalex.org/W2555542996', 'https://openalex.org/W2555587815', 'https://openalex.org/W2569808825', 'https://openalex.org/W2593398483', 'https://openalex.org/W2613192624', 'https://openalex.org/W2626763984', 'https://openalex.org/W2760139353', 'https://openalex.org/W2775284111', 'https://openalex.org/W2789253606', 'https://openalex.org/W2791171303', 'https://openalex.org/W2791865075', 'https://openalex.org/W2792810461', 'https://openalex.org/W2793734783', 'https://openalex.org/W2795466305', 'https://openalex.org/W2801097103', 'https://openalex.org/W2804716061', 'https://openalex.org/W2804785223', 'https://openalex.org/W2808479622', 'https://openalex.org/W2883810676', 'https://openalex.org/W2884942425', 'https://openalex.org/W2889057731', 'https://openalex.org/W2890950898', 'https://openalex.org/W2891571774', 'https://openalex.org/W2896925948', 'https://openalex.org/W2902947590', 'https://openalex.org/W2903216094', 'https://openalex.org/W2934235686', 'https://openalex.org/W2936579961', 'https://openalex.org/W2967876620', 'https://openalex.org/W2983215973', 'https://openalex.org/W2991110084', 'https://openalex.org/W2994722820', 'https://openalex.org/W2998971582', 'https://openalex.org/W3005249228', 'https://openalex.org/W3006168543', 'https://openalex.org/W3011789684', 'https://openalex.org/W3033748663', 'https://openalex.org/W3036709546', 'https://openalex.org/W3043239533', 'https://openalex.org/W3047926371', 'https://openalex.org/W3049453111', 'https://openalex.org/W3090928709', 'https://openalex.org/W3092013556', 'https://openalex.org/W3094159065', 'https://openalex.org/W3094651377', 'https://openalex.org/W3102587633'], 'related_works': ['https://openalex.org/W4390058316', 'https://openalex.org/W4223457571', 'https://openalex.org/W3185130928', 'https://openalex.org/W3154491120', 'https://openalex.org/W2970949995', 'https://openalex.org/W2969424935', 'https://openalex.org/W2273625928', 'https://openalex.org/W2136174202', 'https://openalex.org/W2025902887', 'https://openalex.org/W2023600884'], 'abstract_inverted_index': {'One-carbon': [0], '(C1)': [1], 'substrates': [2, 34], 'are': [3, 35, 52], 'preferred': [4], 'feedstocks': [5], 'for': [6], 'the': [7, 54, 58, 68, 94, 96, 99], 'biomanufacturing': [8], 'industry': [9], 'and': [10, 23, 49, 76, 78, 98], 'have': [11], 'recently': [12], 'gained': [13], 'attention': [14], 'owing': [15], 'to': [16, 31], 'their': [17], 'natural': [18], 'abundance,': [19], 'low': [20], 'production': [21], 'cost': [22], 'availability': [24], 'as': [25], 'industrial': [26], 'by-products.': [27], 'However,': [28], 'native': [29, 69], 'pathways': [30, 82], 'utilize': [32], 'these': [33, 80], 'absent': [36], 'in': [37, 44], 'most': [38], 'biotechnologically': [39], 'relevant': [40], 'microorganisms.': [41, 63], 'Recent': [42], 'advances': [43], 'synthetic': [45, 61], 'biology,': [46], 'genome': [47], 'engineering': [48], 'laboratory': [50], 'evolution': [51], 'enabling': [53], 'first': [55], 'steps': [56], 'towards': [57], 'creation': [59], 'of': [60, 71, 101], 'C1-utilizing': [62, 81], 'Here,': [64], 'we': [65], 'briefly': [66], 'review': [67, 92], 'metabolism': [70], 'methane,': [72], 'methanol,': [73], 'CO2,': [74], 'CO': [75], 'formate,': [77], 'how': [79], 'can': [83], 'be': [84], 'engineered': [85], 'into': [86], 'heterologous': [87], 'hosts.': [88], 'In': [89], 'addition,': [90], 'this': [91], 'analyses': [93], 'potential,': [95], 'challenges': [97], 'perspectives': [100], 'C1-based': [102], 'biomanufacturing.': [103]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3185130928', 'counts_by_year': [{'year': 2024, 'cited_by_count': 28}, {'year': 2023, 'cited_by_count': 34}, {'year': 2022, 'cited_by_count': 31}, {'year': 2021, 'cited_by_count': 6}], 'updated_date': '2024-09-13T16:01:11.132298', 'created_date': '2021-08-02'}