Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3183899443', 'doi': 'https://doi.org/10.1111/cpr.13094', 'title': 'Partial depletion and repopulation of microglia have different effects in the acute MPTP mouse model of Parkinson’s disease', 'display_name': 'Partial depletion and repopulation of microglia have different effects in the acute MPTP mouse model of Parkinson’s disease', 'publication_year': 2021, 'publication_date': '2021-07-26', 'ids': {'openalex': 'https://openalex.org/W3183899443', 'doi': 'https://doi.org/10.1111/cpr.13094', 'mag': '3183899443', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34312932', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8349650'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/cpr.13094', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cpr.13094', 'source': {'id': 'https://openalex.org/S86484535', 'display_name': 'Cell Proliferation', 'issn_l': '0960-7722', 'issn': ['0960-7722', '1365-2184'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cpr.13094', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100404056', 'display_name': 'Qing Li', 'orcid': 'https://orcid.org/0000-0002-1359-8289'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I4210157773', 'display_name': 'Shanghai Model Organisms (China)', 'ror': 'https://ror.org/057c2xb31', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I4210157773']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Qing Li', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'Shanghai Engineering Research Center for Model Organisms Shanghai Model Organisms Center INC Shanghai China'], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}, {'raw_affiliation_string': 'Shanghai Engineering Research Center for Model Organisms Shanghai Model Organisms Center INC Shanghai China', 'institution_ids': ['https://openalex.org/I4210157773']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022983714', 'display_name': 'Chenye Shen', 'orcid': 'https://orcid.org/0000-0001-5673-6170'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Chenye Shen', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101546722', 'display_name': 'Zhaolin Liu', 'orcid': 'https://orcid.org/0000-0001-6161-766X'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Zhaolin Liu', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101902594', 'display_name': 'Yuanyuan Ma', 'orcid': 'https://orcid.org/0000-0002-9945-2634'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Yuanyuan Ma', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100685088', 'display_name': 'Jinghui Wang', 'orcid': 'https://orcid.org/0000-0001-7379-0267'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Jinghui Wang', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000697435', 'display_name': 'Hongtian Dong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Hongtian Dong', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013582226', 'display_name': 'Xiaoshuang Zhang', 'orcid': 'https://orcid.org/0000-0001-5284-8124'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Xiaoshuang Zhang', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003723166', 'display_name': 'Zishan Wang', 'orcid': 'https://orcid.org/0000-0002-5980-4711'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Zishan Wang', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100691656', 'display_name': 'Mei Yu', 'orcid': 'https://orcid.org/0000-0003-3824-6367'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Mei Yu', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047783727', 'display_name': 'Lei Ci', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210157773', 'display_name': 'Shanghai Model Organisms (China)', 'ror': 'https://ror.org/057c2xb31', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I4210157773']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Lei Ci', 'raw_affiliation_strings': ['Shanghai Engineering Research Center for Model Organisms Shanghai Model Organisms Center INC Shanghai China'], 'affiliations': [{'raw_affiliation_string': 'Shanghai Engineering Research Center for Model Organisms Shanghai Model Organisms Center INC Shanghai China', 'institution_ids': ['https://openalex.org/I4210157773']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016853861', 'display_name': 'Ruilin Sun', 'orcid': 'https://orcid.org/0000-0002-7564-1051'}, 'institutions': [{'id': 'https://openalex.org/I4210157773', 'display_name': 'Shanghai Model Organisms (China)', 'ror': 'https://ror.org/057c2xb31', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I4210157773']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Ruilin Sun', 'raw_affiliation_strings': ['Shanghai Engineering Research Center for Model Organisms Shanghai Model Organisms Center INC Shanghai China'], 'affiliations': [{'raw_affiliation_string': 'Shanghai Engineering Research Center for Model Organisms Shanghai Model Organisms Center INC Shanghai China', 'institution_ids': ['https://openalex.org/I4210157773']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026192246', 'display_name': 'Ruling Shen', 'orcid': 'https://orcid.org/0000-0002-7529-810X'}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Ruling Shen', 'raw_affiliation_strings': ['Joint Laboratory for Technology of Model Organism Shanghai Laboratory Animal Research Center and School of Life Science and Technology Tongji University', 'Shanghai Laboratory Animal Research Center Shanghai China'], 'affiliations': [{'raw_affiliation_string': 'Joint Laboratory for Technology of Model Organism Shanghai Laboratory Animal Research Center and School of Life Science and Technology Tongji University', 'institution_ids': ['https://openalex.org/I116953780']}, {'raw_affiliation_string': 'Shanghai Laboratory Animal Research Center Shanghai China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101633308', 'display_name': 'Jian Fei', 'orcid': 'https://orcid.org/0000-0001-7755-0818'}, 'institutions': [{'id': 'https://openalex.org/I116953780', 'display_name': 'Tongji University', 'ror': 'https://ror.org/03rc6as71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I116953780']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Jian Fei', 'raw_affiliation_strings': ['Joint Laboratory for Technology of Model Organism Shanghai Laboratory Animal Research Center and School of Life Science and Technology Tongji University', 'School of Life Science and Technology Tongji University Shanghai China', 'Shanghai Laboratory Animal Research Center Shanghai China'], 'affiliations': [{'raw_affiliation_string': 'Joint Laboratory for Technology of Model Organism Shanghai Laboratory Animal Research Center and School of Life Science and Technology Tongji University', 'institution_ids': ['https://openalex.org/I116953780']}, {'raw_affiliation_string': 'Shanghai Laboratory Animal Research Center Shanghai China', 'institution_ids': []}, {'raw_affiliation_string': 'School of Life Science and Technology Tongji University Shanghai China', 'institution_ids': ['https://openalex.org/I116953780']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100745919', 'display_name': 'Fang Huang', 'orcid': 'https://orcid.org/0000-0002-8658-2755'}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Fang Huang', 'raw_affiliation_strings': ["Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China"], 'affiliations': [{'raw_affiliation_string': "Department of Translational Neuroscience State Key Laboratory of Medical Neurobiology MOE Frontiers Center for Brain Science Jing' an District Centre Hospital of Shanghai Institutes of Brain Science Fudan University Shanghai China", 'institution_ids': ['https://openalex.org/I24943067']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5100404056', 'https://openalex.org/A5022983714', 'https://openalex.org/A5101546722', 'https://openalex.org/A5101902594', 'https://openalex.org/A5100685088', 'https://openalex.org/A5000697435', 'https://openalex.org/A5013582226', 'https://openalex.org/A5003723166', 'https://openalex.org/A5100691656', 'https://openalex.org/A5047783727', 'https://openalex.org/A5016853861', 'https://openalex.org/A5026192246', 'https://openalex.org/A5101633308', 'https://openalex.org/A5100745919'], 'corresponding_institution_ids': ['https://openalex.org/I24943067', 'https://openalex.org/I4210157773', 'https://openalex.org/I24943067', 'https://openalex.org/I24943067', 'https://openalex.org/I24943067', 'https://openalex.org/I24943067', 'https://openalex.org/I24943067', 'https://openalex.org/I24943067', 'https://openalex.org/I24943067', 'https://openalex.org/I24943067', 'https://openalex.org/I4210157773', 'https://openalex.org/I4210157773', 'https://openalex.org/I116953780', 'https://openalex.org/I116953780', 'https://openalex.org/I24943067'], 'apc_list': {'value': 2860, 'currency': 'USD', 'value_usd': 2860, 'provenance': 'doaj'}, 'apc_paid': {'value': 2860, 'currency': 'USD', 'value_usd': 2860, 'provenance': 'doaj'}, 'fwci': 2.95, 'has_fulltext': False, 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.999812, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '54', 'issue': '8', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11266', 'display_name': 'Role of Microglia in Neurological Disorders', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11266', 'display_name': 'Role of Microglia in Neurological Disorders', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10085', 'display_name': "Pathophysiology of Parkinson's Disease", 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10483', 'display_name': 'Roles of Neurotrophins in Nervous System Function', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mptp', 'display_name': 'MPTP', 'score': 0.9761961}, {'id': 'https://openalex.org/keywords/nerve-regeneration', 'display_name': 'Nerve Regeneration', 'score': 0.517598}, {'id': 'https://openalex.org/keywords/neurodegeneration', 'display_name': 'Neurodegeneration', 'score': 0.508897}, {'id': 'https://openalex.org/keywords/neuroinflammation', 'display_name': 'Neuroinflammation', 'score': 0.506182}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.50129557}, {'id': 'https://openalex.org/keywords/dopaminergic-neurons', 'display_name': 'Dopaminergic Neurons', 'score': 0.50082}], 'concepts': [{'id': 'https://openalex.org/C2778674702', 'wikidata': 'https://www.wikidata.org/wiki/Q239816', 'display_name': 'MPTP', 'level': 4, 'score': 0.9761961}, {'id': 'https://openalex.org/C2779830541', 'wikidata': 'https://www.wikidata.org/wiki/Q1622829', 'display_name': 'Microglia', 'level': 3, 'score': 0.903968}, {'id': 'https://openalex.org/C87753298', 'wikidata': 'https://www.wikidata.org/wiki/Q17157137', 'display_name': 'Neuroinflammation', 'level': 3, 'score': 0.80407834}, {'id': 'https://openalex.org/C137183658', 'wikidata': 'https://www.wikidata.org/wiki/Q461076', 'display_name': 'Dopaminergic', 'level': 3, 'score': 0.78475153}, {'id': 'https://openalex.org/C2779734285', 'wikidata': 'https://www.wikidata.org/wiki/Q11085', 'display_name': "Parkinson's disease", 'level': 3, 'score': 0.7289415}, {'id': 'https://openalex.org/C25498285', 'wikidata': 'https://www.wikidata.org/wiki/Q1981368', 'display_name': 'Neuroprotection', 'level': 2, 'score': 0.67290014}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.50129557}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.4401379}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.4349354}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.433914}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.41490024}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3997945}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.37041867}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34542888}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.33926386}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.33274245}, {'id': 'https://openalex.org/C513476851', 'wikidata': 'https://www.wikidata.org/wiki/Q170304', 'display_name': 'Dopamine', 'level': 2, 'score': 0.32984442}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2523535}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.23179588}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/cpr.13094', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cpr.13094', 'source': {'id': 'https://openalex.org/S86484535', 'display_name': 'Cell Proliferation', 'issn_l': '0960-7722', 'issn': ['0960-7722', '1365-2184'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349650', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/cpr.13094', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cpr.13094', 'source': {'id': 'https://openalex.org/S86484535', 'display_name': 'Cell Proliferation', 'issn_l': '0960-7722', 'issn': ['0960-7722', '1365-2184'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.83, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '31671043'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81571232'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '31970908'}], 'datasets': [], 'versions': [], 'referenced_works_count': 75, 'referenced_works': ['https://openalex.org/W1768846296', 'https://openalex.org/W1876850155', 'https://openalex.org/W1920357305', 'https://openalex.org/W1960100142', 'https://openalex.org/W1973392168', 'https://openalex.org/W1985287196', 'https://openalex.org/W2006376003', 'https://openalex.org/W2008386957', 'https://openalex.org/W2060042438', 'https://openalex.org/W2065336907', 'https://openalex.org/W2069893872', 'https://openalex.org/W2104431737', 'https://openalex.org/W2124836944', 'https://openalex.org/W2127381922', 'https://openalex.org/W2140717464', 'https://openalex.org/W2148731774', 'https://openalex.org/W2160073148', 'https://openalex.org/W2196585553', 'https://openalex.org/W2222356562', 'https://openalex.org/W2253007662', 'https://openalex.org/W2343003880', 'https://openalex.org/W2370677464', 'https://openalex.org/W2494229447', 'https://openalex.org/W2512585966', 'https://openalex.org/W2539841050', 'https://openalex.org/W2590458460', 'https://openalex.org/W2594403755', 'https://openalex.org/W2594676718', 'https://openalex.org/W2596835040', 'https://openalex.org/W2598318056', 'https://openalex.org/W2598821444', 'https://openalex.org/W2617655455', 'https://openalex.org/W2619613367', 'https://openalex.org/W2739961516', 'https://openalex.org/W2770582014', 'https://openalex.org/W2779446741', 'https://openalex.org/W2784357120', 'https://openalex.org/W2791700208', 'https://openalex.org/W2792487572', 'https://openalex.org/W2794408899', 'https://openalex.org/W2802993096', 'https://openalex.org/W2804970493', 'https://openalex.org/W2884301844', 'https://openalex.org/W2892332054', 'https://openalex.org/W2894428253', 'https://openalex.org/W2894787694', 'https://openalex.org/W2898726956', 'https://openalex.org/W2917764123', 'https://openalex.org/W2919580190', 'https://openalex.org/W2936059353', 'https://openalex.org/W2936831088', 'https://openalex.org/W2940851310', 'https://openalex.org/W2942943546', 'https://openalex.org/W2949867899', 'https://openalex.org/W2951348834', 'https://openalex.org/W2954319214', 'https://openalex.org/W2969573657', 'https://openalex.org/W2978315680', 'https://openalex.org/W2989129802', 'https://openalex.org/W2991435795', 'https://openalex.org/W2994271391', 'https://openalex.org/W2994774911', 'https://openalex.org/W3005532100', 'https://openalex.org/W3006311963', 'https://openalex.org/W3006708403', 'https://openalex.org/W3007339156', 'https://openalex.org/W3009157977', 'https://openalex.org/W3015066288', 'https://openalex.org/W3022628169', 'https://openalex.org/W3039461072', 'https://openalex.org/W3042183311', 'https://openalex.org/W3082521916', 'https://openalex.org/W3111358404', 'https://openalex.org/W3143826040', 'https://openalex.org/W4294235631'], 'related_works': ['https://openalex.org/W4391340461', 'https://openalex.org/W4310076785', 'https://openalex.org/W4250754689', 'https://openalex.org/W3107395714', 'https://openalex.org/W2965172925', 'https://openalex.org/W2804482952', 'https://openalex.org/W2784357120', 'https://openalex.org/W2090006661', 'https://openalex.org/W2028580402', 'https://openalex.org/W2008060420'], 'abstract_inverted_index': {'Abstract': [0], 'Objectives': [1], "Parkinson's": [2], 'disease': [3], '(PD)': [4], 'is': [5], 'a': [6, 118, 146, 197], 'common': [7], 'neurodegenerative': [8], 'disorder': [9], 'characterized': [10], 'by': [11, 78], 'the': [12, 27, 32, 68, 91, 111, 210, 214], 'progressive': [13], 'and': [14, 22, 37, 45, 81, 129, 135, 216], 'selective': [15], 'degeneration': [16], 'of': [17, 29, 50, 67, 114, 209, 213], 'dopaminergic': [18, 69, 143, 170], 'neurons.': [19], 'Microglial': [20, 124], 'activation': [21, 36], 'neuroinflammation': [23], 'are': [24], 'associated': [25], 'with': [26, 58, 173], 'pathogenesis': [28], 'PD.': [30], 'However,': [31, 159], 'relationship': [33], 'between': [34], 'microglial': [35, 64, 161, 181, 202, 217], 'PD': [38, 194, 222], 'pathology': [39], 'remains': [40], 'to': [41, 54, 89, 187], 'be': [42], 'explored.': [43], 'Materials': [44], 'Methods': [46], 'An': [47], 'acute': [48], 'regimen': [49], 'MPTP': [51, 137, 188], 'was': [52], 'administered': [53], 'adult': [55], 'C57BL/6J': [56], 'mice': [57, 115, 164, 175], 'normal,': [59], 'much': [60], 'reduced': [61], 'or': [62], 'repopulated': [63], 'population.': [65], 'Damages': [66], 'system': [70], 'were': [71, 76, 86], 'comprehensively': [72], 'assessed.': [73], 'Inflammation‐related': [74], 'factors': [75], 'assessed': [77], 'quantitative': [79], 'PCR': [80], 'Multiplex': [82], 'immunoassay.': [83], 'Behavioural': [84], 'tests': [85], 'carried': [87], 'out': [88], 'evaluate': [90], 'motor': [92], 'deficits': [93], 'in': [94, 110, 149, 154, 163, 207, 221], 'MPTP‐challenged': [95], 'mice.': [96, 158, 223], 'Results': [97], 'The': [98], 'receptor': [99], 'for': [100, 121], 'colony‐stimulating': [101], 'factor': [102], '1': [103], 'inhibitor': [104], 'PLX3397': [105], 'could': [106], 'effectively': [107], 'deplete': [108], 'microglia': [109], 'nigrostriatal': [112], 'pathway': [113], 'via': [116], 'feeding': [117], 'PLX3397‐formulated': [119], 'diet': [120, 156], '21': [122], 'days.': [123], 'depletion': [125, 162, 203], 'downregulated': [126], 'both': [127], 'pro‐inflammatory': [128], 'anti‐inflammatory': [130], 'molecule': [131], 'expression': [132], 'at': [133, 176, 196], 'baseline': [134], 'after': [136], 'administration.': [138], 'At': [139], '1d': [140], 'post‐MPTP': [141], 'injection,': [142], 'neurons': [144], 'showed': [145], 'significant': [147], 'reduction': [148], 'PLX3397‐fed': [150], 'mice,': [151], 'but': [152], 'not': [153], 'control': [155], '(CD)‐fed': [157], 'partial': [160, 201], 'exerted': [165], 'little': [166, 205], 'effect': [167, 206], 'on': [168], 'MPTP‐induced': [169], 'injuries': [171], 'compared': [172], 'CD': [174], 'later': [177], 'time': [178], 'points.': [179], 'Interestingly,': [180], 'repopulation': [182], 'brought': [183], 'about': [184], 'apparent': [185], 'resistance': [186], 'intoxication.': [189], 'Conclusions': [190], 'Microglia': [191], 'can': [192], 'inhibit': [193], 'development': [195], 'very': [198], 'early': [199], 'stage;': [200], 'has': [204], 'terms': [208], 'whole': [211], 'process': [212], 'disease;': [215], 'replenishment': [218], 'elicits': [219], 'neuroprotection': [220]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3183899443', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-09-19T22:35:14.696130', 'created_date': '2021-08-02'}