Publication Information

{'id': 'https://openalex.org/W3182231376', 'doi': 'https://doi.org/10.1158/1538-7445.am2021-1568', 'title': 'Abstract 1568: A2aR inhibition enhances the antitumor activity of CTLA4 blockade in mouse Pten-deficient prostate cancer', 'display_name': 'Abstract 1568: A2aR inhibition enhances the antitumor activity of CTLA4 blockade in mouse Pten-deficient prostate cancer', 'publication_year': 2021, 'publication_date': '2021-07-01', 'ids': {'openalex': 'https://openalex.org/W3182231376', 'doi': 'https://doi.org/10.1158/1538-7445.am2021-1568', 'mag': '3182231376'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2021-1568', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5051123041', 'display_name': 'Marco A. De Velasco', 'orcid': 'https://orcid.org/0000-0002-4011-6572'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Marco A. De Velasco', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083740330', 'display_name': 'Yurie Kura', 'orcid': 'https://orcid.org/0009-0000-8785-3177'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yurie Kura', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033730303', 'display_name': 'Noriko Sako', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Noriko Sako', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047104997', 'display_name': 'Naomi Ando', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Naomi Ando', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015524135', 'display_name': 'Kazuko Sakai', 'orcid': 'https://orcid.org/0000-0003-1822-2720'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuko Sakai', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003340825', 'display_name': 'Alwin G. Schuller', 'orcid': 'https://orcid.org/0000-0001-9163-5885'}, 'institutions': [{'id': 'https://openalex.org/I4210150756', 'display_name': 'AstraZeneca (United States)', 'ror': 'https://ror.org/043cec594', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I105036370', 'https://openalex.org/I4210150756']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alwin Schuller', 'raw_affiliation_strings': ['2Oncology R&D, AstraZeneca, Waltham, ME.'], 'affiliations': [{'raw_affiliation_string': '2Oncology R&D, AstraZeneca, Waltham, ME.', 'institution_ids': ['https://openalex.org/I4210150756']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072709086', 'display_name': 'Kazutoshi Fujita', 'orcid': 'https://orcid.org/0000-0002-6774-7497'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazutoshi Fujita', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103082965', 'display_name': 'Masahiro Nozawa', 'orcid': 'https://orcid.org/0000-0001-9950-4636'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masahiro Nozawa', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047840224', 'display_name': 'Kazuhiro Yoshimura', 'orcid': 'https://orcid.org/0000-0002-6598-0391'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuhiro Yoshimura', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004282323', 'display_name': 'Kazuto Nishio', 'orcid': 'https://orcid.org/0000-0002-8275-0846'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuto Nishio', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058934672', 'display_name': 'Hirotsugu Uemura', 'orcid': 'https://orcid.org/0000-0002-3665-9523'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hirotsugu Uemura', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.299, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.543075, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 67, 'max': 72}, 'biblio': {'volume': '81', 'issue': '13_Supplement', 'first_page': '1568', 'last_page': '1568'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11193', 'display_name': 'Adenosine and Purinergic Signaling', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11193', 'display_name': 'Adenosine and Purinergic Signaling', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/conditional-gene-knockout', 'display_name': 'Conditional gene knockout', 'score': 0.49933052}], 'concepts': [{'id': 'https://openalex.org/C2777609662', 'wikidata': 'https://www.wikidata.org/wiki/Q416356', 'display_name': 'PTEN', 'level': 4, 'score': 0.87227774}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.71340233}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.6722985}, {'id': 'https://openalex.org/C164659718', 'wikidata': 'https://www.wikidata.org/wiki/Q5159266', 'display_name': 'Conditional gene knockout', 'level': 4, 'score': 0.49933052}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.49637824}, {'id': 'https://openalex.org/C2776235491', 'wikidata': 'https://www.wikidata.org/wiki/Q9625', 'display_name': 'Prostate', 'level': 3, 'score': 0.49564445}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.4509508}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.4275636}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.42280647}, {'id': 'https://openalex.org/C2778468042', 'wikidata': 'https://www.wikidata.org/wiki/Q273976', 'display_name': 'Blockade', 'level': 3, 'score': 0.41004854}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.332864}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.33196414}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29842448}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.25816852}, {'id': 'https://openalex.org/C86554907', 'wikidata': 'https://www.wikidata.org/wiki/Q285613', 'display_name': 'PI3K/AKT/mTOR pathway', 'level': 3, 'score': 0.20597649}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.19075537}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.15422791}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2021-1568', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.79}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4362567669', 'https://openalex.org/W4362545125', 'https://openalex.org/W2803102053', 'https://openalex.org/W2792929645', 'https://openalex.org/W2563241643', 'https://openalex.org/W2400504790', 'https://openalex.org/W2312375518', 'https://openalex.org/W2142008762', 'https://openalex.org/W2109763600', 'https://openalex.org/W1980245127'], 'abstract_inverted_index': {'Abstract': [0], 'Extracellular': [1], 'adenosine': [2, 21], 'impairs': [3], 'immune': [4, 14, 304], 'function': [5], 'in': [6, 32, 44, 68, 137, 156, 176, 211, 276, 283, 346], 'tumors': [7, 76, 178], 'and': [8, 38, 59, 101, 110, 131, 179, 209, 302, 367], 'limits': [9], 'the': [10, 54, 116, 151, 169, 181, 243, 265, 294, 340, 355], 'efficacy': [11], 'of': [12, 57, 71, 93, 118, 123, 147, 161, 202, 239, 297, 343, 354], 'anti-CTAL4': [13], 'checkpoint': [15, 305], 'blockade.': [16], 'We': [17], 'previously': [18], 'showed': [19, 104], 'that': [20, 112], '2A': [22], 'receptor': [23], '(A2aR)': [24], 'blockade': [25, 66, 299, 345], 'with': [26, 64, 84, 115, 126, 225, 264, 300], 'AZD4635': [27, 58, 142, 301], 'moderately': [28], 'inhibited': [29], 'tumor': [30, 228], 'growth,': [31], 'part': [33], 'by': [34, 154], 'improving': [35], 'antigen': [36], 'presentation': [37], 'cytotoxic': [39], 'T': [40, 106, 132, 173], 'cell': [41, 108, 129, 174], '(CTL)': [42], 'activity': [43, 56, 201, 342], 'mouse': [45, 237, 347], 'Pten-deficient': [46, 72, 162, 221, 226, 348], 'prostate': [47, 73, 163, 177, 241, 309, 349], 'cancer.': [48, 74, 164, 310], 'Here,': [49], 'we': [50], 'continue': [51], 'to': [52, 143, 171, 188, 194, 261, 280, 292], 'investigate': [53], 'antitumor': [55, 152, 197, 200, 341], 'its': [60], 'effects': [61], 'when': [62, 254], 'combined': [63], 'CTLA4': [65, 344], '(aCTLA4)': [67], 'preclinical': [69, 290], 'models': [70], 'Prostate': [75], 'from': [77, 273], 'Pten': [78], 'conditional': [79, 220, 233], 'knockout': [80, 222, 235], '(KO)': [81], 'mice': [82, 223, 279], 'treated': [83, 139, 278, 285], 'aCTLA4': [85, 148, 303], 'for': [86, 307, 358], 'five': [87], 'days': [88, 275, 282], 'had': [89], 'increased': [90, 105, 136], 'expression': [91, 121], 'levels': [92, 122], 'adenosinergic': [94], 'genes.': [95], 'Furthermore,': [96], 'gene': [97], 'expression,': [98], 'flow': [99], 'cytometric': [100], 'IHC': [102], 'analyses': [103], 'regulatory': [107], 'differentiation': [109, 130], 'accumulation': [111], 'was': [113, 206, 256], 'offset': [114], 'addition': [117], 'AZD4635.': [119], 'Moreover,': [120], 'genes': [124], 'associated': [125], 'Th': [127], '1': [128], 'cell-mediated': [133], 'cytotoxicity': [134], 'were': [135], 'AZD4635/aCTLA4': [138, 182, 244, 255, 284], 'tumors.': [140], 'Adding': [141], 'a': [144, 195, 212, 231], 'four-week': [145], 'regimen': [146], 'therapy': [149, 187, 260], 'improved': [150, 269], 'response': [153], 'two-fold': [155], 'an': [157], 'early-stage': [158], 'intervention': [159], 'model': [160, 217, 238], 'Androgen': [165], 'deprivation': [166], '(AD)': [167], 'has': [168], 'potential': [170], 'promote': [172], 'infiltration': [175], 'using': [180, 218], 'treatment': [183, 204, 245], 'combination': [184, 205, 246, 296], 'as': [185, 258], 'neoadjuvant': [186, 259], 'AD': [189], 'via': [190], 'surgical': [191], 'castration': [192], 'led': [193], 'greater': [196], 'response.': [198], 'The': [199], 'this': [203], 'further': [207], 'examined': [208], 'confirmed': [210], 'subcutaneous': [213], 'syngeneic': [214], 'genome-derived': [215], 'allograft': [216], 'tumor-bearing': [219], 'grafted': [224], 'CRPC': [227], 'fragments.': [229], 'In': [230], 'Pten/Trp53': [232], 'double': [234], '(DKO)': [236], 'advanced': [240], 'cancer,': [242], 'did': [247], 'not': [248], 'improve': [249], 'overall': [250], 'survival': [251, 271], 'rates.': [252], 'However,': [253], 'used': [257], 'AR': [262], 'inhibition': [263, 306, 338], 'anti-androgen': [266], 'apalutamide,': [267], 'it': [268], 'median': [270], 'time': [272], '21': [274], 'monotherapy': [277], '34': [281], 'mice.': [286], 'These': [287], 'results': [288], 'provide': [289], 'evidence': [291], 'support': [293], 'rational': [295], 'A2AR': [298], 'PTEN-deficient': [308], 'Citation': [311], 'Format:': [312], 'Marco': [313], 'A.': [314], 'De': [315], 'Velasco,': [316], 'Yurie': [317], 'Kura,': [318], 'Noriko': [319], 'Sako,': [320], 'Naomi': [321], 'Ando,': [322], 'Kazuko': [323], 'Sakai,': [324], 'Alwin': [325], 'Schuller,': [326], 'Kazutoshi': [327], 'Fujita,': [328], 'Masahiro': [329], 'Nozawa,': [330], 'Kazuhiro': [331], 'Yoshimura,': [332], 'Kazuto': [333], 'Nishio,': [334], 'Hirotsugu': [335], 'Uemura.': [336], 'A2aR': [337], 'enhances': [339], 'cancer': [350], '[abstract].': [351], 'In:': [352], 'Proceedings': [353], 'American': [356], 'Association': [357], 'Cancer': [359, 373], 'Research': [360], 'Annual': [361], 'Meeting': [362], '2021;': [363], '2021': [364], 'Apr': [365], '10-15': [366], 'May': [368], '17-21.': [369], 'Philadelphia': [370], '(PA):': [371], 'AACR;': [372], 'Res': [374], '2021;81(13_Suppl):Abstract': [375], 'nr': [376], '1568.': [377]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3182231376', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-12-12T05:07:42.321989', 'created_date': '2021-07-19'}