Publication Information

{'id': 'https://openalex.org/W3179084811', 'doi': 'https://doi.org/10.1016/j.kint.2021.06.026', 'title': 'Significance of HLA-DQ in kidney transplantation: time to reevaluate human leukocyte antigen–matching priorities to improve transplant outcomes? An expert review and recommendations', 'display_name': 'Significance of HLA-DQ in kidney transplantation: time to reevaluate human leukocyte antigen–matching priorities to improve transplant outcomes? An expert review and recommendations', 'publication_year': 2021, 'publication_date': '2021-07-08', 'ids': {'openalex': 'https://openalex.org/W3179084811', 'doi': 'https://doi.org/10.1016/j.kint.2021.06.026', 'mag': '3179084811', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34246656'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.kint.2021.06.026', 'pdf_url': 'http://www.kidney-international.org/article/S0085253821006578/pdf', 'source': {'id': 'https://openalex.org/S97303050', 'display_name': 'Kidney International', 'issn_l': '0085-2538', 'issn': ['0085-2538', '1523-1755'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.kidney-international.org/article/S0085253821006578/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067260564', 'display_name': 'Anat R. Tambur', 'orcid': 'https://orcid.org/0000-0002-0320-9825'}, 'institutions': [{'id': 'https://openalex.org/I111979921', 'display_name': 'Northwestern University', 'ror': 'https://ror.org/000e0be47', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111979921']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Anat R. Tambur', 'raw_affiliation_strings': ['Department of Surgery, Comprehensive Transplant Center, Northwestern University, Chicago, Illinois, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Comprehensive Transplant Center, Northwestern University, Chicago, Illinois, USA', 'institution_ids': ['https://openalex.org/I111979921']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017267546', 'display_name': 'Vasilis Kosmoliaptsis', 'orcid': 'https://orcid.org/0000-0001-7298-1387'}, 'institutions': [{'id': 'https://openalex.org/I34931013', 'display_name': 'National Institute for Health Research', 'ror': 'https://ror.org/0187kwz08', 'country_code': 'GB', 'type': 'government', 'lineage': ['https://openalex.org/I34931013']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Vasilis Kosmoliaptsis', 'raw_affiliation_strings': ['Department of Surgery, University of Cambridge, Cambridge, UK', 'National Institute of Health Research (NIHR) Blood and Transplant Research Unit in Organ Donation and Transplantation and NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Health Research (NIHR) Blood and Transplant Research Unit in Organ Donation and Transplantation and NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK', 'institution_ids': ['https://openalex.org/I34931013']}, {'raw_affiliation_string': 'Department of Surgery, University of Cambridge, Cambridge, UK', 'institution_ids': ['https://openalex.org/I241749']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021544227', 'display_name': 'Frans H.J. Claas', 'orcid': 'https://orcid.org/0000-0003-4157-6201'}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Frans H.J. Claas', 'raw_affiliation_strings': ['Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands', 'institution_ids': ['https://openalex.org/I2800006345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061551777', 'display_name': 'Roslyn B. Mannon', 'orcid': 'https://orcid.org/0000-0003-1776-3680'}, 'institutions': [{'id': 'https://openalex.org/I59130452', 'display_name': 'University of Nebraska Medical Center', 'ror': 'https://ror.org/00thqtb16', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I59130452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Roslyn B. Mannon', 'raw_affiliation_strings': ['Department of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA', 'institution_ids': ['https://openalex.org/I59130452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020473629', 'display_name': 'Peter Nickerson', 'orcid': 'https://orcid.org/0000-0002-7393-7799'}, 'institutions': [{'id': 'https://openalex.org/I46247651', 'display_name': 'University of Manitoba', 'ror': 'https://ror.org/02gfys938', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I46247651']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Peter Nickerson', 'raw_affiliation_strings': ['Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada', 'institution_ids': ['https://openalex.org/I46247651']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5025590861', 'display_name': 'Maarten Naesens', 'orcid': 'https://orcid.org/0000-0002-5625-0792'}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Maarten Naesens', 'raw_affiliation_strings': ['Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}], 'institution_assertions': [], 'countries_distinct_count': 5, 'institutions_distinct_count': 7, 'corresponding_author_ids': ['https://openalex.org/A5067260564'], 'corresponding_institution_ids': ['https://openalex.org/I111979921'], 'apc_list': {'value': 3200, 'currency': 'USD', 'value_usd': 3200, 'provenance': 'doaj'}, 'apc_paid': {'value': 3200, 'currency': 'USD', 'value_usd': 3200, 'provenance': 'doaj'}, 'fwci': 3.489, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 55, 'citation_normalized_percentile': {'value': 0.989848, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '100', 'issue': '5', 'first_page': '1012', 'last_page': '1022'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10373', 'display_name': 'Renal Transplantation Outcomes and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2747', 'display_name': 'Transplantation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10373', 'display_name': 'Renal Transplantation Outcomes and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2747', 'display_name': 'Transplantation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10999', 'display_name': 'Organ Transplantation Techniques and Outcomes', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/histocompatibility-testing', 'display_name': 'Histocompatibility Testing', 'score': 0.6190164}, {'id': 'https://openalex.org/keywords/histocompatibility', 'display_name': 'Histocompatibility', 'score': 0.50140285}, {'id': 'https://openalex.org/keywords/clinical-significance', 'display_name': 'Clinical Significance', 'score': 0.477409}, {'id': 'https://openalex.org/keywords/hla-dq', 'display_name': 'HLA-DQ', 'score': 0.44290403}, {'id': 'https://openalex.org/keywords/graft-rejection', 'display_name': 'Graft rejection', 'score': 0.4132119}], 'concepts': [{'id': 'https://openalex.org/C188280979', 'wikidata': 'https://www.wikidata.org/wiki/Q911125', 'display_name': 'Human leukocyte antigen', 'level': 3, 'score': 0.87712216}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.68755066}, {'id': 'https://openalex.org/C2909478873', 'wikidata': 'https://www.wikidata.org/wiki/Q3991680', 'display_name': 'Histocompatibility Testing', 'level': 4, 'score': 0.6190164}, {'id': 'https://openalex.org/C2911091166', 'wikidata': 'https://www.wikidata.org/wiki/Q106419912', 'display_name': 'Transplantation', 'level': 2, 'score': 0.5991008}, {'id': 'https://openalex.org/C165064840', 'wikidata': 'https://www.wikidata.org/wiki/Q1321061', 'display_name': 'Matching (statistics)', 'level': 2, 'score': 0.5648253}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.5354322}, {'id': 'https://openalex.org/C2780303639', 'wikidata': 'https://www.wikidata.org/wiki/Q740909', 'display_name': 'Kidney transplantation', 'level': 3, 'score': 0.5163068}, {'id': 'https://openalex.org/C202965653', 'wikidata': 'https://www.wikidata.org/wiki/Q2664028', 'display_name': 'Histocompatibility', 'level': 4, 'score': 0.50140285}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.48016658}, {'id': 'https://openalex.org/C63363279', 'wikidata': 'https://www.wikidata.org/wiki/Q5133848', 'display_name': 'Clinical significance', 'level': 2, 'score': 0.477409}, {'id': 'https://openalex.org/C2779910283', 'wikidata': 'https://www.wikidata.org/wiki/Q5630144', 'display_name': 'HLA-DQ', 'level': 5, 'score': 0.44290403}, {'id': 'https://openalex.org/C3019230761', 'wikidata': 'https://www.wikidata.org/wiki/Q1765748', 'display_name': 'Graft rejection', 'level': 3, 'score': 0.4132119}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.34339163}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29297385}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.19711643}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.15078536}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.07411885}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.06650218}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C197754878', 'wikidata': 'https://www.wikidata.org/wiki/Q80711', 'display_name': 'Haplotype', 'level': 4, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016030', 'descriptor_name': 'Kidney Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006084', 'descriptor_name': 'Graft Rejection', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D006084', 'descriptor_name': 'Graft Rejection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006085', 'descriptor_name': 'Graft Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006680', 'descriptor_name': 'HLA Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006683', 'descriptor_name': 'HLA-DQ Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006650', 'descriptor_name': 'Histocompatibility Testing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007518', 'descriptor_name': 'Isoantibodies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014019', 'descriptor_name': 'Tissue Donors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.kint.2021.06.026', 'pdf_url': 'http://www.kidney-international.org/article/S0085253821006578/pdf', 'source': {'id': 'https://openalex.org/S97303050', 'display_name': 'Kidney International', 'issn_l': '0085-2538', 'issn': ['0085-2538', '1523-1755'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://lirias.kuleuven.be/handle/123456789/680051', 'pdf_url': 'https://lirias.kuleuven.be/bitstream/123456789/680051/3/PIIS0085253821006578.pdf', 'source': {'id': 'https://openalex.org/S4306401954', 'display_name': 'Lirias (KU Leuven)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I99464096', 'host_organization_name': 'KU Leuven', 'host_organization_lineage': ['https://openalex.org/I99464096'], 'host_organization_lineage_names': ['KU Leuven'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34246656', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.kint.2021.06.026', 'pdf_url': 'http://www.kidney-international.org/article/S0085253821006578/pdf', 'source': {'id': 'https://openalex.org/S97303050', 'display_name': 'Kidney International', 'issn_l': '0085-2538', 'issn': ['0085-2538', '1523-1755'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320319990', 'funder_display_name': 'National Institute for Health and Care Research', 'award_id': 'PDF-2016-09-065'}], 'datasets': [], 'versions': [], 'referenced_works_count': 76, 'referenced_works': ['https://openalex.org/W1486598251', 'https://openalex.org/W1492421523', 'https://openalex.org/W1545464200', 'https://openalex.org/W155025199', 'https://openalex.org/W1605691525', 'https://openalex.org/W1754287689', 'https://openalex.org/W1880509226', 'https://openalex.org/W1933257343', 'https://openalex.org/W1969347248', 'https://openalex.org/W1972879732', 'https://openalex.org/W1973801066', 'https://openalex.org/W1975206040', 'https://openalex.org/W1993959375', 'https://openalex.org/W1995815906', 'https://openalex.org/W1997256865', 'https://openalex.org/W2001433044', 'https://openalex.org/W2009169637', 'https://openalex.org/W2042021216', 'https://openalex.org/W2053932938', 'https://openalex.org/W2067090279', 'https://openalex.org/W2075323385', 'https://openalex.org/W2076756340', 'https://openalex.org/W2078462430', 'https://openalex.org/W2080590614', 'https://openalex.org/W2093207255', 'https://openalex.org/W2098974363', 'https://openalex.org/W2109968192', 'https://openalex.org/W2127707359', 'https://openalex.org/W2140510160', 'https://openalex.org/W2142966586', 'https://openalex.org/W2143041251', 'https://openalex.org/W2153943197', 'https://openalex.org/W2160215044', 'https://openalex.org/W2160607034', 'https://openalex.org/W2165003884', 'https://openalex.org/W2271650886', 'https://openalex.org/W2281327633', 'https://openalex.org/W2295343146', 'https://openalex.org/W2315888271', 'https://openalex.org/W2323204318', 'https://openalex.org/W2326384578', 'https://openalex.org/W2327763294', 'https://openalex.org/W2406823310', 'https://openalex.org/W2413560223', 'https://openalex.org/W2574164618', 'https://openalex.org/W2592185057', 'https://openalex.org/W2622236527', 'https://openalex.org/W2739465434', 'https://openalex.org/W2740183634', 'https://openalex.org/W2743263207', 'https://openalex.org/W2745419313', 'https://openalex.org/W2802054652', 'https://openalex.org/W2806323893', 'https://openalex.org/W2888694884', 'https://openalex.org/W2889924561', 'https://openalex.org/W2900181891', 'https://openalex.org/W2910757321', 'https://openalex.org/W2917231788', 'https://openalex.org/W2917302778', 'https://openalex.org/W2919912179', 'https://openalex.org/W2944208717', 'https://openalex.org/W2950264161', 'https://openalex.org/W2962672512', 'https://openalex.org/W2968170869', 'https://openalex.org/W2975303308', 'https://openalex.org/W3012424886', 'https://openalex.org/W3018244286', 'https://openalex.org/W3019204751', 'https://openalex.org/W3024570138', 'https://openalex.org/W3028136291', 'https://openalex.org/W3037695579', 'https://openalex.org/W3048196734', 'https://openalex.org/W3083160147', 'https://openalex.org/W3084291565', 'https://openalex.org/W3092258281', 'https://openalex.org/W3126558304'], 'related_works': ['https://openalex.org/W4302567174', 'https://openalex.org/W4213122016', 'https://openalex.org/W4211036251', 'https://openalex.org/W2764589280', 'https://openalex.org/W2417908454', 'https://openalex.org/W2411452380', 'https://openalex.org/W2305987044', 'https://openalex.org/W2185211112', 'https://openalex.org/W2086577699', 'https://openalex.org/W2046621922'], 'abstract_inverted_index': {'The': [0, 31, 216, 247, 556, 1583, 1764, 1778, 1795, 1838, 1937, 1990, 2244, 2607, 3040, 3184], 'weight': [1, 217, 1438], 'of': [2, 28, 68, 79, 107, 136, 147, 184, 196, 200, 206, 218, 244, 284, 295, 323, 352, 363, 400, 412, 416, 422, 527, 558, 578, 586, 647, 666, 719, 738, 784, 802, 820, 828, 856, 862, 895, 919, 958, 985, 1002, 1006, 1017, 1025, 1054, 1073, 1097, 1129, 1140, 1151, 1171, 1176, 1248, 1265, 1276, 1285, 1384, 1396, 1429, 1457, 1549, 1564, 1572, 1579, 1655, 1740, 1750, 1801, 1827, 1844, 1850, 1903, 1913, 1922, 1930, 1949, 1967, 1971, 1984, 1992, 2025, 2032, 2043, 2067, 2119, 2142, 2171, 2204, 2226, 2246, 2273, 2290, 2298, 2300, 2371, 2433, 2439, 2465, 2476, 2482, 2490, 2549, 2556, 2609, 2615, 2634, 2637, 2648, 2664, 2668, 2688, 2725, 2729, 2736, 2741, 2773, 2786, 2803, 2814, 2853, 2875, 2890, 2918, 2922, 2932, 2951, 2988, 2999, 3032, 3042, 3100, 3126, 3135, 3150, 3158, 3168, 3175, 3186, 3214, 3226, 3236, 3246, 3251, 3268, 3331, 3349, 3363, 3405, 3430, 3454, 3467, 3486, 3496, 3525, 3533, 3573, 3601, 3621, 3653, 3702, 3709, 3723, 3757, 3808, 3842, 3859, 3886, 3893, 3922, 3948, 3986, 3991, 4009], 'human': [3, 219, 612, 821, 1074, 1130, 1885, 3497, 3675], 'leukocyte': [4, 220, 613, 822, 1075, 1131, 1886, 3498, 3676], 'antigen': [5, 221, 614, 823, 1076, 1132, 2768, 3499, 3677], '(HLA)': [6, 222, 615, 3500], 'matching': [7, 46, 150, 223, 262, 366, 616, 635, 649, 668, 716, 724, 764, 792, 1077, 1153, 1194, 1278, 1348, 1390, 1421, 1442, 1574, 1589, 1605, 1615, 1624, 1694, 2045, 2492], 'in': [8, 13, 20, 134, 152, 224, 229, 236, 350, 368, 486, 650, 682, 749, 805, 866, 892, 964, 998, 1046, 1078, 1220, 1260, 1289, 1326, 1332, 1355, 1399, 1443, 1447, 1535, 1595, 1735, 1908, 1987, 1997, 2046, 2176, 2207, 2345, 2401, 2442, 2496, 2527, 2801, 2893, 2935, 2992, 3011, 3026, 3044, 3054, 3080, 3094, 3204, 3212, 3276, 3293, 3323, 3375, 3433, 3475, 3490, 3681, 3707, 3927, 3953, 3979, 4019], 'kidney': [9, 153, 225, 369, 441, 445, 460, 504, 529, 595, 652, 830, 900, 923, 967, 1008, 1079, 1107, 1135, 1397, 1454, 1466, 1536, 1592, 1889, 2096, 2149, 2177, 2229, 2252, 2275, 2346, 2378, 2415, 2522, 2925, 2956, 3048, 3071, 3368, 3431, 3515, 3628, 3710, 3894, 3959], 'allocation': [10, 226, 638, 721, 757, 780, 1155, 1222, 1445, 1455, 1467, 1537, 1565, 1593, 1687, 1730, 1752, 1890, 2097], 'algorithms,': [11, 227], 'especially': [12, 228], 'the': [14, 26, 37, 77, 89, 132, 145, 157, 162, 166, 173, 182, 230, 242, 253, 293, 305, 348, 361, 373, 378, 382, 389, 398, 450, 510, 525, 562, 569, 576, 605, 626, 644, 687, 698, 735, 750, 775, 782, 787, 826, 867, 893, 928, 1041, 1047, 1052, 1172, 1191, 1274, 1283, 1314, 1320, 1327, 1356, 1386, 1392, 1420, 1426, 1437, 1448, 1452, 1545, 1550, 1561, 1573, 1653, 1658, 1681, 1799, 1806, 1842, 1927, 1933, 1968, 1982, 1993, 1999, 2026, 2041, 2047, 2116, 2227, 2418, 2434, 2557, 2685, 2726, 2751, 2787, 2804, 2808, 2812, 2850, 2888, 2916, 2930, 2949, 2989, 3018, 3027, 3081, 3087, 3127, 3178, 3189, 3201, 3233, 3266, 3271, 3277, 3306, 3324, 3347, 3353, 3388, 3391, 3396, 3406, 3410, 3434, 3443, 3451, 3464, 3479, 3513, 3555, 3598, 3643, 3651, 3654, 3682, 3696], 'United': [15, 231, 688, 868, 1321, 1449, 1901, 2048, 2090, 3028, 3082, 3325, 3435], 'States,': [16, 232, 1322, 2049], 'has': [17, 60, 233, 276, 2266], 'been': [18, 61, 234, 277, 747, 2267, 3911], 'devalued': [19, 235], 'a': [21, 65, 137, 237, 281, 353, 435, 542, 618, 667, 832, 870, 981, 999, 1103, 1109, 1909, 2029, 2315, 2463, 2499, 2546, 2571, 2646, 2665, 2689, 2704, 2770, 2923, 2945, 2953, 2969, 3003, 3133, 3156, 3166, 3173, 3334, 3586, 3839], 'stepwise': [22, 238], 'manner,': [23, 239], 'supported': [24, 240], 'by': [25, 120, 241, 336, 464, 1040, 1159, 1195, 1279, 1943, 2645, 2750, 2821, 3302], 'introduction': [27, 243, 3652], 'modern': [29, 245, 785, 1048], 'immunosuppression.': [30, 246], 'intent': [32, 248], 'was': [33, 249, 707, 1344, 1996, 2050, 3321], 'further': [34, 177, 250, 393, 3482], 'to': [35, 50, 76, 115, 126, 131, 180, 209, 251, 266, 292, 331, 342, 347, 396, 425, 521, 571, 631, 640, 696, 708, 1014, 1021, 1032, 1163, 1189, 1205, 1252, 1334, 1368, 1373, 1414, 1435, 1440, 1497, 1541, 1652, 1713, 1716, 1719, 1784, 1811, 1859, 2021, 2173, 2235, 2271, 2338, 2404, 2413, 2471, 2559, 2595, 2623, 2721, 2807, 2844, 2983, 3023, 3115, 3137, 3141, 3148, 3160, 3170, 3222, 3263, 3288, 3305, 3312, 3329, 3395, 3442, 3543, 3658, 3698, 3778, 3867], 'reduce': [36, 210, 252, 426, 1436], 'observed': [38, 158, 254, 374, 3010, 3079], 'ethnic/racial': [39, 255], 'disparity,': [40, 256], 'as': [41, 118, 257, 334, 617, 697, 717, 1282, 1570, 1577, 1869, 1940, 2641, 2792, 2826, 2828, 3078, 3282, 3400, 3473, 3549, 3899, 3901], 'data': [42, 258, 1037, 3084], 'emerged': [43, 259], 'associating': [44, 260], 'HLA': [45, 86, 111, 149, 186, 261, 302, 327, 365, 402, 648, 715, 752, 791, 795, 896, 962, 1034, 1055, 1098, 1152, 1277, 1347, 1357, 1389, 1417, 1441, 1551, 1691, 1751, 1917, 1924, 1935, 2002, 2033, 2044, 2146, 2491, 2494, 2639, 2682, 2733, 2759, 2840, 2933, 3350, 3364, 3469, 3508, 3625, 3729, 4014], 'with': [47, 263, 440, 443, 488, 568, 734, 961, 1019, 1030, 1100, 1102, 1294, 1304, 1500, 1597, 1809, 1822, 2180, 2422, 2462, 2525, 2684, 2929, 2997, 3013, 3030, 3194, 3333, 3352, 3372, 3417, 3650, 3745, 3810, 3838, 3861, 3988, 4051], 'decreased': [48, 264, 2012], 'access': [49, 125, 265, 341, 1177, 1333, 2101, 3304], 'transplantation': [51, 127, 267, 343, 433, 712, 865, 1335, 1398, 2286, 2523, 3049, 3502, 3960], 'for': [52, 128, 268, 344, 438, 560, 593, 607, 620, 662, 778, 1028, 1310, 1339, 1388, 1488, 1505, 1520, 1527, 1606, 1616, 1625, 1693, 1711, 1759, 1772, 1787, 1805, 1862, 1875, 2092, 2102, 2627, 2896, 3172, 3342, 3409, 3412, 3481, 3645, 3728, 3874], 'African': [53, 269, 1340, 1350], 'American': [54, 270, 1341, 1351], 'patients.': [55, 271, 1164, 1342, 3196, 3551], 'In': [56, 272, 2015, 2794], 'recent': [57, 273], 'years,': [58, 274, 511, 3344], 'it': [59, 275, 2018, 3320, 3460], 'increasingly': [62, 278], 'recognized': [63, 279, 2820], 'that': [64, 280, 598, 1346, 2023, 2269, 2743, 2832, 2858, 2915, 3265, 3327, 3463, 3597, 3742, 3806, 3857], 'leading': [66, 282, 2547], 'cause': [67, 283, 2548], 'graft': [69, 104, 285, 320, 505, 540, 581, 622, 803, 1026, 1061, 1105, 1136, 1337, 1988, 2013, 2055, 2129, 2174, 2230, 2313, 2411, 2550, 2569, 2702, 2837, 2967, 3373, 3438, 3540, 3577, 3679, 3753, 3780, 3820, 3879, 3908, 4017], 'loss': [70, 286, 1027, 1062, 3439, 3754], 'is': [71, 140, 287, 356, 434, 754, 772, 797, 1157, 1250, 1258, 1539, 1618, 1680, 1798, 1815, 1841, 1926, 2019, 2545, 2617, 2677, 2719, 2799, 3052, 3241, 3261, 3398, 3471], 'chronic': [72, 288, 2068], 'antibody-mediated': [73, 289, 2125, 2440, 3504, 3843, 4052], 'rejection,': [74, 290, 574, 4053, 4056], 'attributed': [75, 291, 2234], 'development': [78, 294, 1929, 2123, 2206, 2299, 2611, 2735, 2889, 3485], 'de': [80, 108, 296, 324, 1630, 1914, 2007, 2120, 2143, 2181, 2279, 2301, 2341, 2372, 2391, 3527, 3582, 3602, 3622, 3749, 3811, 3862, 3887, 3923, 3954], 'novo': [81, 109, 297, 325, 1915, 2121, 2144, 2182, 2280, 2302, 2342, 2373, 2392, 3528, 3583, 3603, 3623, 3750, 3812, 3832, 3863, 3888, 3924, 3955], 'antibodies': [82, 92, 112, 298, 308, 328, 1931, 2004, 2249, 2344, 2376, 2495, 2742, 2763, 2841, 2892, 3604, 3759, 3775, 3835, 3866, 4015, 4048], 'against': [83, 96, 299, 312, 1932, 2765, 3674, 3762], 'mismatched': [84, 300, 1495, 1934, 2855, 3501], 'donor': [85, 97, 301, 313, 1365, 1672, 2374, 2766, 2856, 2876, 3005, 3307, 3456, 3607, 3815, 3868], 'expressed': [87, 303, 2749], 'on': [88, 103, 194, 304, 319, 410, 583, 727, 790, 825, 859, 1057, 1134, 1391, 1544, 1600, 1728, 1816, 2035, 2052, 2128, 2250, 2612, 2887, 2948, 3017, 3346, 3370, 3450, 3553, 3576, 3589, 3904, 4016], 'graft.': [90, 306], 'These': [91, 307], 'are': [93, 309, 1567, 1733, 1770, 2784, 2842, 3210, 3219, 3274, 3285, 3299, 3310, 3403, 3559, 3836, 4049], 'most': [94, 310, 779, 3743, 3756], 'frequently': [95, 311], 'HLA-DQ': [98, 314, 1588, 2940, 3574, 3608, 3703, 3774, 3816, 3869, 3889, 3956], 'molecules.': [99, 315], 'Beyond': [100, 316, 2417], 'their': [101, 317, 515, 720, 1221, 2293, 2456, 2836, 2854, 3229, 3294, 3902], 'impact': [102, 183, 318, 399, 577, 855, 894, 1053, 2245, 2608, 2947, 3041, 3921], 'survival,': [105, 321], 'generation': [106, 322, 2740], 'donor-specific': [110, 326, 1916, 2003, 2145, 2183, 2247, 2343, 3529, 3624, 3834, 3925, 3957, 4013], 'also': [113, 329, 1182, 2755, 2774, 3518], 'leads': [114, 330], 'increased': [116, 332, 507, 2469, 2474, 2632, 3313, 3523], 'sensitization,': [117, 333], 'measured': [119, 335], 'panel-reactive': [121, 337, 2652, 2655, 2658, 3108, 3563], 'antibody': [122, 338, 1918, 2147, 2205, 2406, 2653, 2656, 2823, 3109, 3530, 3626, 3958], 'metrics.': [123, 339], 'Consequently,': [124, 340, 1451, 3296], 'patients': [129, 345, 439, 487, 513, 1292, 1352, 1362, 1513, 1789, 1867, 2291, 2621, 2833, 2894, 2991, 3001, 3045, 3068, 3101, 3119, 3128, 3151, 3179, 3238, 3248, 3284, 3298, 3448, 3520, 3727, 3744, 3809, 3860, 3987], 'returning': [130, 346, 3441], 'waitlist': [133, 349, 1361, 2990, 3019], 'need': [135, 351, 570, 592, 3213, 3480], 'second': [138, 354, 3215], 'transplant': [139, 355, 517, 596, 901, 959, 1049, 1058, 1111, 1360, 1580, 2036, 2100, 2276, 2444, 2501, 2691, 2926, 3072, 3104, 3131, 3273, 3292, 3337, 3369, 3592, 3802, 3846, 3876, 3981], 'compromised.': [141, 357], 'Herein,': [142, 358, 602], 'we': [143, 359, 603, 3594], 'address': [144, 360], 'implications': [146, 362, 2420], 'reduced': [148, 364, 3303], 'policies': [151, 367, 1434], 'allocation.': [154, 370], 'We': [155, 176, 371, 392], 'highlight': [156, 372, 589, 604], 'diminished': [159, 375], 'outcome': [160, 376, 804, 1581, 2056, 3781], 'data,': [161, 198, 377, 414, 2985], 'significant': [163, 379, 743, 982, 3399, 3840, 3872], 'financial': [164, 380, 565, 2419, 3393], 'burden,': [165, 381], 'long-term': [167, 383, 2228, 2237, 3983], 'health': [168, 384], 'consequences,': [169, 385], 'and,': [170, 386], 'more': [171, 387, 2397, 3220, 3286, 3447], 'important,': [172, 388, 741, 2223], 'unintended': [174, 390], 'consequences.': [175, 391], 'provide': [178, 394], 'recommendations': [179, 395], 'examine': [181, 397], 'donor-recipient': [185, 401, 611, 1923, 3468], 'class': [187, 403, 728], 'II': [188, 404], 'and': [189, 204, 405, 420, 466, 518, 523, 564, 575, 580, 609, 624, 628, 636, 686, 701, 710, 731, 759, 762, 769, 810, 835, 992, 995, 1063, 1066, 1166, 1174, 1203, 1212, 1216, 1232, 1262, 1297, 1306, 1316, 1336, 1363, 1394, 1424, 1493, 1524, 1555, 1608, 1622, 1664, 1700, 1702, 1708, 1722, 1864, 1898, 2011, 2124, 2138, 2169, 2287, 2368, 2394, 2408, 2436, 2455, 2480, 2484, 2493, 2593, 2781, 2838, 2884, 2939, 3020, 3025, 3036, 3059, 3073, 3090, 3124, 3154, 3279, 3309, 3440, 3484, 3503, 3545, 3557, 3578, 3617, 3730, 3755, 3804, 3817, 3845, 3870, 3878, 3907, 3920, 3951, 4060], 'specifically': [190, 406, 3606], 'HLA-DQα1β1': [191, 407], 'mismatching,': [192, 408], 'focusing': [193, 409], 'collection': [195, 411], 'appropriate': [197, 413], 'application': [199, 415], 'creative': [201, 417], 'simulation': [202, 418], 'approaches,': [203, 419], 'reconsideration': [205, 421], 'best': [207, 423, 1654], 'practices': [208, 424], 'inequalities': [211, 427], 'while': [212, 428, 713], 'optimizing': [213, 429], 'patient': [214, 430, 584, 1814, 2558, 2613, 3556, 3579], 'outcomes.': [215, 431], 'Kidney': [432, 1225, 1230, 1669, 1742, 1852, 1881], 'standard-of-care': [436], 'treatment': [437], 'failure,': [442, 2551, 3541], '>75,000': [444], 'transplants': [446, 924, 1029], 'performed': [447], 'annually': [448], 'around': [449], 'globe.1Ying': [451], 'T.': [452, 480], 'Shi': [453], 'B.': [454, 1095, 1127], 'Kelly': [455], 'P.J.': [456], 'et': [457, 536, 660, 818, 853, 889, 917, 948, 955, 1382, 1464, 1637, 2063, 2087, 2136, 2167, 2201, 2309, 2334, 2519, 2566, 2587, 2698, 2873, 2963, 3361, 3615, 3663, 3670, 3713, 3720, 3765, 3772, 3823, 3830, 3918, 3945, 3976, 4007], 'al.Death': [458], 'after': [459, 539, 1106, 2009, 2312, 2377, 2568, 2589, 2701, 2920, 2966, 3782], 'transplantation:': [461, 831, 1108, 1670, 2498], 'an': [462, 590, 799, 2402, 3162, 3522], 'analysis': [463, 1139], 'era': [465], 'time': [467, 2553, 3315, 3548], 'post-transplant.J': [468], 'Am': [469, 2349], 'Soc': [470, 2350], 'Nephrol.': [471, 2256, 2351, 2598], '2020;': [472, 2576], '31:': [473], '2887-2899Crossref': [474], 'PubMed': [475, 497, 551, 673, 842, 878, 906, 940, 975, 1087, 1119, 1146, 1408, 1480, 1956, 1976, 2077, 2108, 2156, 2190, 2217, 2260, 2324, 2355, 2385, 2450, 2509, 2536, 2579, 2602, 2713, 2909, 2978, 3383, 3635, 3689, 3794, 3851, 3934, 3965, 4034], 'Scopus': [476, 498, 552, 674, 843, 879, 907, 941, 976, 1088, 1120, 1147, 1409, 1481, 1957, 1977, 2078, 2109, 2157, 2191, 2218, 2261, 2325, 2356, 2386, 2451, 2510, 2537, 2603, 2714, 2910, 2979, 3384, 3636, 3690, 3795, 3852, 3935, 3966, 4035], '(32)': [477], 'Google': [478, 500, 554, 676, 845, 881, 909, 943, 978, 1090, 1122, 1149, 1411, 1483, 1959, 1979, 2080, 2111, 2159, 2193, 2220, 2263, 2327, 2358, 2388, 2453, 2512, 2539, 2580, 2605, 2716, 2912, 2981, 3386, 3638, 3692, 3739, 3797, 3854, 3937, 3968, 3999, 4037], 'Scholar,2Jenssen': [479], 'Hartmann': [481], 'A.': [482, 2200, 2239, 2331, 2364, 2582], 'Post-transplant': [483], 'diabetes': [484], 'mellitus': [485], 'solid': [489, 3590, 3897], 'organ': [490, 637, 1364, 1371, 1444, 1673, 2478, 2497, 2674, 2752, 3591], 'transplants.Nat': [491], 'Rev': [492, 2255], 'Endocrinol.': [493], '2019;': [494, 875, 903], '15:': [495, 2188], '172-188Crossref': [496], '(88)': [499], 'Scholar': [501, 555, 677, 944, 979, 1271, 1412, 1484, 1649, 1679, 1980, 2221, 2264, 2454, 2540, 2606, 2717, 2913, 3639, 3693, 3740, 3798, 3855], 'Unfortunately,': [502], 'although': [503, 2797], 'survival': [506, 623, 997], 'significantly': [508], 'over': [509, 1872, 2224], 'many': [512, 2629], 'lose': [514, 2292], 'life-saving': [516], 'face': [519], 'return': [520, 2555, 2594, 3542], 'dialysis,': [522, 3544], 'potentially': [524], 'gift': [526], 'another': [528], 'transplant.3Schrezenmeier': [530], 'E.': [531, 2304, 2693, 2958], 'Lehner': [532, 2305, 2694, 2959], 'L.J.': [533, 2306, 2695, 2960, 4040], 'Merkel': [534, 2307, 2696, 2961], 'M.': [535, 2308, 2514, 2561, 2584, 2697, 2962, 3358, 3715, 3825, 3944], 'al.What': [537, 2310, 2699, 2964], 'happens': [538, 2311, 2700, 2965], 'loss?': [541, 2314, 2703, 2968], 'large,': [543, 2316, 2705, 2970], 'long-term,': [544, 2317, 2706, 2971], 'single-center': [545, 808, 2318, 2707, 2866, 2972], 'observation.Transpl': [546, 2319, 2708, 2973], 'Int.': [547, 874, 2320, 2709, 2900, 2974, 3785], '2021;': [548, 2321, 2710, 2975], '34:': [549, 2322, 2711, 2976, 4027], '732-742Crossref': [550, 2323, 2712, 2977], '(3)': [553, 2326, 2715, 2980], 'shortage': [557], 'kidneys': [559], 'transplantation,': [561, 2010, 3077, 3516], 'medical': [563], 'ramifications': [566], 'associated': [567, 2421, 3837, 4050], 'treat': [572], 'allograft': [573, 653, 996, 2069, 2178, 2253, 2347, 2591, 3726, 3905], 'immunosuppression': [579, 2399], 'dysfunction/loss': [582], 'quality': [585, 2614], 'life': [587, 2616], 'all': [588, 3581], 'unmet': [591], 'improving': [594, 651], 'outcomes': [597, 827, 861, 1338, 1395, 4018], 'must': [599], 'be': [600, 2233, 2624, 2643, 2819, 2825, 3339], 'addressed.': [601], 'case': [606], 'better': [608], 'alternative': [610], 'strategy': [619], 'prolonging': [621], 'discuss': [625], 'hurdles': [627], 'potential': [629, 1928, 2690, 2815], 'approaches': [630, 2649], 'reach': [632], 'this': [633, 2016, 2795, 2822, 3111, 3145, 3491, 3646], 'goal.HLA': [634], 'policiesSubsequent': [639], 'initial': [641, 1562], 'studies': [642, 809, 2113], 'demonstrating': [643, 3883], 'beneficial': [645], 'role': [646, 706, 1072, 1275, 1983, 2042, 3947], 'survival,4Terasaki': [654], 'P.I.': [655, 914, 1946, 1961, 3719], 'Vredevoe': [656], 'D.L.': [657], 'Porter': [658], 'K.A.': [659], 'al.Serotyping': [661], 'homotransplantation,': [663], 'V:': [664], 'evaluation': [665], 'scheme.Transplantation.': [669], '1966;': [670], '4:': [671], '688-699Crossref': [672], '(20)': [675], 'transplant-related': [678], 'agencies': [679], 'were': [680, 1038, 1324, 1558, 2994, 3009, 3198, 3694, 3760], 'established': [681], 'both': [683, 806, 3554], 'Europe': [684], '(Eurotransplant)': [685], 'States': [689, 3326], '(South-Eastern': [690], 'Organ': [691, 699, 1082, 1430, 1904, 2093, 3088], 'Procurement': [692, 700, 3089], 'Foundation,': [693], 'later': [694, 736], 'referred': [695], 'Transplant': [702, 932, 1043, 3091], 'Network': [703, 1428, 1902, 2091, 3092], '[OPTN]).': [704], 'Their': [705], 'facilitate': [709], 'promote': [711], 'supporting': [714, 2028], 'part': [718, 1571, 1578, 2785], 'algorithms.': [722, 3661], 'Initial': [723], 'strategies': [725], 'focused': [726], 'I': [729], 'HLA-A': [730, 1317, 1607], 'HLA-B': [732, 1315, 1609], 'antigens,': [733, 2734], 'addition': [737], 'HLA-DR.': [739], 'More': [740, 1726, 2222], 'no': [742], 'advances': [744], 'have': [745, 2114, 2769, 2845, 2944, 3105, 3132, 3165, 3585, 3910], 'since': [746], 'made': [748], 'way': [751], 'compatibility': [753, 1133], 'incorporated': [755], 'into': [756, 1154, 1590], 'policies,': [758], 'HLA-A,': [760, 990, 1214, 1491, 1696, 2880, 2936], 'HLA-B,': [761, 991, 1215, 1492, 1697, 2937], 'HLA-DR': [763, 993, 1217, 1299, 1494, 1509, 1617], '(aiming': [765], 'at': [766, 1313, 2651, 2878, 3366, 3521], '0-A,': [767], '0-B,': [768], '0-DR': [770], 'mismatches)': [771], 'still': [773, 798], 'considered': [774], 'gold': [776], 'standard': [777], 'agencies.With': [781], 'advent': [783], 'immunosuppression,': [786, 3539], 'relative': [788], 'emphasis': [789, 1599], 'declined.': [793], 'Nevertheless,': [794], 'mismatching': [796, 824, 897, 1056, 1925, 2034, 3470, 3509], 'independent': [800], 'predictor': [801], 'large': [807], 'registry': [811], 'analyses.5Shi': [812], 'X.': [813, 817, 3360], 'Liu': [814], 'R.': [815, 2563, 3829, 3975], 'Xie': [816], 'al.Effect': [819, 1383, 4008], 'pediatric': [829, 899, 1773, 1788, 3193, 3237, 3278, 4020], 'systematic': [833], 'review': [834], 'meta-analysis.Nephrol': [836], 'Dial': [837, 2574], 'Transplant.': [838, 1083, 1115, 1952, 2152, 2186, 2532, 2575, 3379, 3631, 4025], '2017;': [839, 2352, 2599], '32:': [840, 876], '1939-1948Crossref': [841], '(4)': [844], 'Scholar,': [846, 882, 910, 1091, 1123, 2160, 2194, 3938, 3969, 4000, 4038], '6Mumford': [847], 'L.': [848, 2333], 'Maxwell': [849], 'H.': [850, 2565], 'Ahmad': [851], 'N.': [852, 2516], 'al.The': [854, 956, 1465, 2064, 3946], 'changing': [857, 1385], 'practice': [858], 'improved': [860], 'paediatric': [863], 'renal': [864, 2208, 2443, 2590, 2898, 3725, 3783, 3801, 3929], 'Kingdom:': [869], '25': [871], 'years': [872, 1016, 1523, 2284, 2297], 'review.Transpl': [873], '751-761Crossref': [877], '(17)': [880], '7Ruck': [883], 'J.M.': [884, 916, 3767], 'Jackson': [885], 'A.M.': [886], 'Massie': [887], 'A.B.': [888], 'al.Temporal': [890], 'changes': [891], 'among': [898, 1179, 3118, 3695, 3891], 'recipients.Transplantation.': [902], '103:': [904], '1267-1271Crossref': [905], '(7)': [908], '8Takemoto': [911], 'S.': [912, 2360], 'Terasaki': [913, 3718], 'Cecka': [915], 'al.Survival': [918], 'nationally': [920], 'shared,': [921], 'HLA-matched': [922], 'from': [925, 969, 1010, 1419, 2285, 3086, 3200, 3537], 'cadaveric': [926], 'donors:': [927], 'UNOS': [929, 2809], 'Scientific': [930], 'Renal': [931, 3423], 'Registry.N': [933], 'Engl': [934, 1402, 2071], 'J': [935, 1114, 1403, 1951, 2072, 2151, 2185, 2531, 2597, 3378, 3630], 'Med.': [936, 1404, 2073], '1992;': [937], '327:': [938], '834-839Crossref': [939], '(180)': [942], 'For': [945, 1186, 1244, 1531, 2761, 3318], 'example,': [946, 2762, 2796, 3319], 'Williams': [947], 'al.9Williams': [949], 'R.C.': [950], 'Opelz': [951, 1069, 2487], 'G.': [952, 1070, 1093, 1125, 2425, 2488, 2518, 3669], 'McGarvey': [953], 'C.J.': [954, 1461], 'risk': [957, 1024, 2475, 2481, 2917, 3524, 3841, 3873], 'failure': [960, 2175, 2231, 2592, 2921], 'mismatch': [963, 1099, 1300, 1312, 1766, 1780, 1797, 1824, 1840, 3351, 3365], 'first': [965, 1007, 1807, 2924, 3103, 3130, 3190, 3230, 3272, 3336, 3354, 3367, 3514, 3697], 'adult': [966, 1004, 1498, 3195], 'allografts': [968, 1009], 'deceased': [970, 1011, 1671, 2673, 3004, 3455], 'donors.Transplantation.': [971], '2016;': [972, 2447], '100:': [973], '1094-1102Crossref': [974], '(94)': [977], 'demonstrated': [980, 2914], 'linear': [983], 'relationship': [984], 'hazard': [986], 'ratios': [987], 'between': [988, 1359, 2001, 2731, 3067], 'incremental': [989], 'mismatches': [994, 1286, 2877, 2934], 'US': [1000, 3202], 'cohort': [1001], '189,141': [1003], 'recipients': [1005, 2179, 2277, 3708, 3803, 3892], 'donors,': [1012], 'equivalent': [1013, 1251, 1540, 1800, 1826, 1843], '994,558': [1015], 'follow-up,': [1018], '13%': [1020, 3021], '64%': [1022, 3099], 'higher': [1023, 1370], '1': [1031, 1501, 1506, 1533], '6': [1033, 1213], 'mismatches.': [1035], 'Similar': [1036, 3007, 3881], 'reported': [1039, 3856], 'Collaborative': [1042], 'Study,': [1044], 'even': [1045], 'era,': [1050], 'highlighting': [1051], 'outcomes,': [1059, 2037], 'including': [1060], 'immunosuppression-related': [1064], 'morbidity': [1065], 'mortality.10Susal': [1067], 'C.': [1068, 2131, 2162, 2486, 3610], 'Current': [1071], 'transplantation.Curr': [1080], 'Opin': [1081], '2013;': [1084, 1472, 2214, 2382, 3931, 3962], '18:': [1085], '438-444Crossref': [1086], '(96)': [1089], '11Opelz': [1092], 'Dohler': [1094, 1126], 'Association': [1096], 'death': [1101], 'functioning': [1104], 'collaborative': [1110, 2500], 'study': [1112, 2502], 'report.Am': [1113], '2012;': [1116, 1973, 2153, 2257, 2506, 3632, 3786, 3848], '12:': [1117, 2154, 3633], '3031-3038Crossref': [1118], '(61)': [1121, 1978], '12Opelz': [1124], 'Effect': [1128], 'survival:': [1137], 'comparative': [1138], 'two': [1141], 'decades.Transplantation.': [1142], '2007;': [1143], '84:': [1144], '137-143Crossref': [1145], '(232)': [1148], 'ScholarImplementation': [1150], 'algorithms': [1156, 1446], 'achieved': [1158], 'providing': [1160, 3642], 'priority': [1161, 1184, 1387, 1486, 1517, 1756, 1871], 'points': [1162, 1281, 1296, 1308, 1504, 1519, 1526, 1710, 1786, 1861], 'Donor': [1165], 'recipient': [1167], 'demographics,': [1168], 'geography,': [1169], 'size': [1170], 'population,': [1173, 2805], 'equity': [1175], 'considerations,': [1178], 'other': [1180, 1729, 2758, 3896], 'factors,': [1181], 'influence': [1183], 'points.': [1185, 1254], 'instance,': [1187], 'specific': [1188, 2375], 'HLA,': [1190, 1884], 'Eurotransplant': [1192, 1234, 1880], 'emphasizes': [1193], 'allotting': [1196], '400.00,': [1197], '333.33,': [1198], '267.67,': [1199], '200.00,': [1200], '133.33,': [1201], '66.67,': [1202], '0.00': [1204], '0,': [1206, 1704], '1,': [1207, 1241, 1647, 1721], '2,': [1208], '3,': [1209, 1720, 3477], '4,': [1210], '5,': [1211], 'mismatches,': [1218, 1724], 'respectively,': [1219, 3143], 'system': [1223, 1456, 1538, 1552, 1585], '(Eurotransplant': [1224], 'Allocation': [1226, 1882], 'System13Eurotransplant.': [1227], 'Chapter': [1228], '4': [1229, 1715, 1785], '(ETKAS': [1231], 'ESP).': [1233], 'Manual–version': [1235], '2021': [1236], 'March': [1237, 1268, 1676, 1745, 1855], '16.https://www.eurotransplant.org/wp-content/uploads/2020/01/H4-Kidney-2021.1-March-2021.pdfDate': [1238], 'accessed:': [1239, 1267, 1645, 1675, 1744, 1854], 'April': [1240, 3095, 3205], '2021Google': [1242, 1270, 1648, 1678, 1747, 1857], 'Scholar).': [1243], 'reference,': [1245, 1532], 'each': [1246, 1298, 1311], 'year': [1247, 1808, 3421], 'wait-time': [1249], '33.3': [1253], 'A': [1255, 1962, 2865, 3640], 'reverse': [1256], 'tactic': [1257], 'utilized': [1259], 'Australia': [1261], 'New': [1263, 1290], 'Zealand,14Ministry': [1264], 'Healthhttps://www.health.govt.nz/system/files/documents/pages/nrts-nz-kidney-allocation-scheme-march2020.pdfDate': [1266], '20,': [1269], 'which': [1272, 1557, 2038], 'value': [1273], 'deducting': [1280], 'number': [1284, 2931, 3235], 'increases.': [1287], 'Thus,': [1288, 1603], 'Zealand,': [1291], 'start': [1293], '6000': [1295, 1845], 'eliminates': [1301], '2200': [1302], 'points,': [1303, 1621], '900': [1305], '800': [1307], 'eliminated': [1309], 'loci,': [1318], 'respectively.In': [1319], 'concerns': [1323], 'raised': [1325], 'late': [1328, 2251], '1990s': [1329], 'about': [1330, 2288, 3098, 3244, 3649], 'disparities': [1331], 'It': [1343, 2265, 2718, 2830], 'identified': [1345, 1559], 'disadvantages': [1349], 'because': [1353, 2724], 'differences': [1354], 'makeup': [1358], 'populations': [1366], 'led': [1367], 'comparatively': [1369], 'offers': [1372], 'Caucasian': [1374], 'ancestry': [1375], 'recipients.15Roberts': [1376], 'J.P.': [1377], 'Wolfe': [1378], 'R.A.': [1379], 'Bragg-Gresham': [1380], 'J.L.': [1381], 'rates': [1393], 'minority': [1400, 2103], 'groups.N': [1401], '2004;': [1405], '350:': [1406], '545-551Crossref': [1407], '(119)': [1410], 'Proposals': [1413], 'remove': [1415], 'some': [1416, 1515], 'loci': [1418, 1548, 1610, 1692, 2886], 'algorithm': [1422, 1688, 1810], 'followed,': [1423], 'ultimately,': [1425], 'OPTN/United': [1427], 'Sharing': [1431, 2094], '(UNOS)': [1432], 'adopted': [1433], 'given': [1439], 'States.': [1450], 'current': [1453], 'UNOS16Friedewald': [1458], 'J.J.': [1459], 'Samana': [1460], 'Kasiske': [1462], 'B.L.': [1463], 'system.Surg': [1468], 'Clin': [1469], 'North': [1470], 'Am.': [1471], '93:': [1473, 1974], '1395-1406Abstract': [1474], 'Full': [1475, 1477, 2904, 2906, 3789, 3791, 4029, 4031], 'Text': [1476, 1478, 2905, 2907, 3790, 3792, 4030, 4032], 'PDF': [1479, 2908, 3793, 4033], '(106)': [1482], 'assigns': [1485], 'only': [1487, 1682, 1776, 2746, 3116], 'allocating': [1489], '0': [1490, 1508, 1723, 1765, 1779, 1796, 1823, 1839], 'organs': [1496], 'patients,': [1499, 3208], 'or': [1502, 1507, 3139, 3216, 3895], '2': [1503, 1718, 1782], 'mismatch,': [1510], 'respectively.': [1511, 1725], 'Pediatric': [1512, 1866, 3207], 'receive': [1514, 2396], 'additional': [1516, 1547, 2423, 3163, 3291], '(4': [1518], 'ages': [1521, 1528], '0–10': [1522, 1791], '3': [1525, 1860], '11–17': [1529], 'years).': [1530], 'point': [1534, 1832], '365': [1542], 'days': [1543], 'waitlist.Three': [1546], '(HLA-C,': [1553], 'HLA-DQ,': [1554, 1701], 'HLA-DP),': [1556], 'following': [1560, 3188, 3228, 3270], 'implementation': [1563], 'priority,': [1566], 'rarely': [1568], 'included': [1569], 'algorithm,': [1575], 'nor': [1576], 'analysis.': [1582], 'French': [1584], 'had': [1586, 2859, 3865, 3871], 'introduced': [1587], 'its': [1591], 'scheme': [1594], '2015,': [1596], 'differential': [1598], 'different': [1601, 2732], 'loci.': [1602, 2941], 'full': [1604, 1614, 1623], 'receives': [1611], '100': [1612, 1628], 'points;': [1613], 'allotted': [1619], '400': [1620, 1768], 'DQ': [1626, 3833], 'adds': [1627], 'points.17Agence': [1629], 'la': [1631], 'BiomédecineProcedures': [1632], "d'application": [1633], 'des': [1634, 1639], 'regles': [1635], 'repartition': [1636], "d'attribution": [1638], 'greffons': [1640], 'preleves': [1641], 'sur': [1642], 'personne': [1643], 'decedde.https://www.agence-biomedecine.fr/IMG/pdf/v25guide-regles-de-repartition.pdfDate': [1644], 'June': [1646], 'Of': [1650], 'note,': [1651], 'our': [1656], 'knowledge,': [1657], 'British': [1659, 1893], 'National': [1660, 1894], 'Health': [1661, 1666, 1895], 'System': [1662, 1896, 3425], 'Blood': [1663, 1897], 'Transplant18National': [1665], 'ServicePOL186/11': [1667], '—': [1668], 'allocation.https://nhsbtdbe.blob.core.windows.net/umbraco-assets-corp/22127/pol186.pdfDate': [1674], '21,': [1677, 1746, 1856], 'agency': [1683], 'whose': [1684], 'recently': [1685], 'revised': [1686], 'considers': [1689], '5(!)': [1690], 'purposes,': [1695], 'HLA-Cw,': [1698], 'HLA-DR,': [1699, 2938], 'removes': [1703], '100,': [1705], '150,': [1706], '250,': [1707], '500': [1709, 1828], '9': [1712], '10,': [1714], '8,': [1717], 'details': [1727], 'systems': [1731], 'worldwide': [1732], 'provided': [1734], 'Table': [1736], '1.19Transplant': [1737], 'Manitoba': [1738, 1848], 'Gift': [1739, 1849], 'Life.': [1741, 1851], 'allocation.https://www.transplantmanitoba.ca/transplant-program/kidney-allocationDate': [1743, 1853], 'ScholarTable': [1748], '1Examples': [1749], 'schemesAllocation': [1753], 'organizationAllocation': [1754], 'systemHLA': [1755], "pointsPoints'": [1757], 'equivalency': [1758], '1-year': [1760], 'wait': [1761, 3547], 'timeEurotransplantETKASConsider': [1762], 'A-B-DR.': [1763], '=': [1767, 1781], 'points.Points': [1769], 'doubled': [1771], 'patients.33.3': [1774], 'PointsUNOSKASConsider': [1775], 'DR.': [1777], 'points.Up': [1783], 'aged': [1790], 'y.1.0': [1792], 'PointFrenchConsider': [1793], 'A-B-DR-DQ.': [1794], '600': [1802], 'points.10': [1803], 'Points': [1804, 1830], 'incorporate': [1812], 'where': [1813], 'dialysisNHSBTConsider': [1817], 'A-B-C-DR-DQ.': [1818], 'Point': [1819], 'deduction': [1820], 'system,': [1821], 'being': [1825], 'points.365': [1829], '(1': [1831], 'per': [1833, 3420], 'day)New': [1834], 'ZealandPoint': [1835], 'elimination': [1836], 'system.': [1837], 'points.12': [1846], 'PointsCanada19Transplant': [1847], 'ScholarUp': [1858], 'HLA-DRβ1/3/4/5': [1863], 'HLA-DQβ1.': [1865], 'treated': [1868], 'high': [1870, 2727, 2771, 2827, 3224, 3700, 3884, 3989], 'adults,': [1873], 'except': [1874], 'highly': [1876], 'sensitized': [1877, 3550], 'patients.1.0': [1878], 'PointETKAS,': [1879], 'System;': [1883], 'antigen;': [1887], 'KAS,': [1888], 'system;': [1891], 'NHSBT,': [1892], 'Transplant;': [1899], 'UNOS,': [1900], 'Sharing.': [1905], 'Open': [1906], 'table': [1907], 'new': [1910], 'tab': [1911], 'Consequences': [1912, 3552], 'developmentAn': [1919], 'important': [1920, 2020, 2720, 3262], 'consequence': [1921], 'antigens.': [1936, 2760], 'Humoral': [1938, 1947], 'Theory,': [1939], 'put': [1941], 'forth': [1942], 'Paul': [1944], 'Terasaki,20Terasaki': [1945], 'theory': [1948, 1970, 1995], 'transplantation.Am': [1950], '2003;': [1953, 2074, 3686], '3:': [1954], '665-673Crossref': [1955], '(512)': [1958], 'Scholar,21Terasaki': [1960], 'personal': [1963], 'perspective:': [1964], '100-year': [1965], 'history': [1966, 2066], 'humoral': [1969, 1985, 1994, 2847], 'transplantation.Transplantation.': [1972], '751-756Crossref': [1975], 'highlighted': [1981], 'alloimmunity': [1986], 'outcome.': [1989, 3821], 'novelty': [1991], 'emphasizing': [1998], 'association': [2000], '(DSAs)': [2005], 'developing': [2006, 2390, 3526], 'novo,': [2008], 'survival.': [2014], 'context,': [2017], 'appreciate': [2022, 2722, 3596], 'much': [2024], 'evidence': [2027, 3644], 'diminishing': [2030], 'effect': [2031, 2118, 3466, 3588, 3647, 3903], 'underpinned': [2039], 'deemphasizing': [2040], 'based': [2051], 'relatively': [2053], 'short-term': [2054], 'data.22Nankivell': [2057], 'B.J.': [2058, 3356], 'Borrows': [2059], 'R.J.': [2060, 3771], 'Fung': [2061], 'C.L.': [2062], 'natural': [2065], 'nephropathy.N': [2070], '349:': [2075], '2326-2333Crossref': [2076], '(1645)': [2079], 'Scholar,23Delmonico': [2081], 'F.L.': [2082], 'Milford': [2083], 'E.L.': [2084], 'Goguen': [2085], 'J.': [2086, 2198, 2429, 4044], 'al.A': [2088], 'novel': [2089], 'region': [2095], 'plan': [2098], 'improves': [2099], 'candidates.Transplantation.': [2104], '1999;': [2105], '68:': [2106], '1875-1879Crossref': [2107], '(15)': [2110, 2511], 'ScholarMultiple': [2112], 'shown': [2115, 2268, 3053, 3322, 3474], 'detrimental': [2117, 3465, 3587], 'DSA': [2122, 2281, 2610, 2861, 3575, 3704, 3751, 3813, 3864, 3890], 'rejection': [2126, 2336, 2441, 3505, 3844, 3906, 3978], '(ABMR)': [2127], 'outcome.24Wiebe': [2130], 'Gibson': [2132, 2163, 3611], 'I.W.': [2133, 2164, 3612], 'Blydt-Hansen': [2134, 2165, 3613], 'T.D.': [2135, 2166, 3614], 'al.Evolution': [2137, 3616], 'clinical': [2139, 2369, 2435, 3618], 'pathologic': [2140, 3619], 'correlations': [2141, 3620], 'post': [2148, 3627], 'transplant.Am': [2150, 3629], '1157-1167Crossref': [2155, 3634], '(708)': [2158, 3637], '25Wiebe': [2161], 'al.Rates': [2168], 'determinants': [2170], 'progression': [2172], 'antibody.Am': [2184], '2015;': [2187, 4026], '2921-2930Crossref': [2189], '(228)': [2192], '26Mehra': [2195], 'N.K.': [2196], 'Siddiqui': [2197], 'Baranwal': [2199], 'al.Clinical': [2202], 'relevance': [2203], 'transplantation.Ann': [2209], 'N': [2210], 'Y': [2211], 'Acad': [2212], 'Sci.': [2213], '1283:': [2215], '30-42Crossref': [2216], '(22)': [2219], 'half': [2225, 3177], 'can': [2232, 2642, 2824, 2943], 'DSA-mediated': [2236], 'rejection.27Loupy': [2238], 'Hill': [2240], 'G.S.': [2241], 'Jordan': [2242], 'S.C.': [2243], 'anti-HLA': [2248], 'failure.Nat': [2254], '8:': [2258], '348-357Crossref': [2259], '(269)': [2262], 'up': [2270, 3985], '30%': [2272], 'nonsensitized': [2274], 'develop': [2278, 3223], 'within': [2282, 2295], '10': [2283], '40%': [2289, 3330], 'grafts': [2294, 3747], '5': [2296], 'DSA.3Schrezenmeier': [2303], 'Scholar,28Aubert': [2328], 'O.': [2329, 2870], 'Loupy': [2330], 'Hidalgo': [2332], 'al.Antibody-mediated': [2335, 3977], 'due': [2337], 'preexisting': [2339], 'versus': [2340, 3050, 4011], 'recipients.J': [2348], '28:': [2353], '1912-1923Crossref': [2354], '(149)': [2357], 'Scholar,29Lionaki': [2359], 'Panagiotellis': [2361], 'K.': [2362], 'Iniotaki': [2363], 'Boletis': [2365, 3666], 'J.N.': [2366, 3667], 'Incidence': [2367], 'significance': [2370], 'transplantation.Clin': [2379], 'Dev': [2380], 'Immunol.': [2381], '2013:': [2383], '849835Crossref': [2384], '(27)': [2387, 3691], 'ScholarPatients': [2389], 'HLA-DSA': [2393, 2737], 'ABMR': [2395, 2544], 'potent': [2398], 'regimens': [2400], 'attempt': [2403], 'suppress': [2405], 'formation': [2407, 2862], 'thus': [2409], 'mitigate': [2410], 'injury': [2412], 'salvage': [2414], 'function.': [2416], 'therapies30Muduma': [2424], 'Odeyemi': [2426], 'I.': [2427], 'Smith-Palmer': [2428], 'Pollock': [2430], 'R.F.': [2431], 'Review': [2432], 'economic': [2437], 'burden': [2438, 3394], 'recipients.Adv': [2445], 'Ther.': [2446], '33:': [2448], '345-356Crossref': [2449], '(14)': [2452], 'limited': [2457, 3452], 'efficacy,': [2458], 'immunosuppressive': [2459], 'drugs': [2460], 'come': [2461], 'multitude': [2464], 'adverse': [2466, 3535], 'effects': [2467, 3536], '(e.g.,': [2468], 'susceptibility': [2470], 'opportunistic': [2472], 'infections,': [2473], 'malignancy,': [2477], 'toxicity,': [2479], 'hypertension': [2483], 'diabetes).31Susal': [2485], 'Impact': [2489], 'view.Methods': [2503], 'Mol': [2504], 'Biol.': [2505], '882:': [2507], '267-277Crossref': [2508], 'Scholar,32Tonelli': [2513], 'Wiebe': [2515], 'Knoll': [2517], 'al.Systematic': [2520], 'review:': [2521], 'compared': [2524], 'dialysis': [2526, 3401], 'clinically': [2528], 'relevant': [2529], 'outcomes.Am': [2530], '2011;': [2533, 3996], '11:': [2534], '2093-2109Crossref': [2535], '(712)': [2538], 'As': [2541], 'mentioned': [2542], 'above,': [2543], 'often': [2552, 2738, 3211], 'necessitating': [2554], 'dialysis.33Bonani': [2560], 'Achermann': [2562], 'Seeger': [2564], 'al.Dialysis': [2567], 'loss:': [2570], 'Swiss': [2572], 'experience.Nephrol': [2573], '35:': [2577], '2182-2190Crossref': [2578], 'Scholar,34Brar': [2581], 'Markell': [2583], 'Stefanov': [2585], 'D.G.': [2586], 'al.Mortality': [2588], 'dialysis.Am': [2596], '45:': [2600], '180-186Crossref': [2601], '(26)': [2604], 'therefore': [2618], 'significant.Among': [2619], 'those': [2620, 2747, 3074], 'fortunate': [2622], 'medically': [2625], 'suitable': [2626], 'retransplantation,': [2628, 2996], 'will': [2630], 'show': [2631], 'levels': [2633, 3225, 3990], 'sensitization': [2635, 2919, 3043, 3187, 3227, 3269], '(presence': [2636], 'preformed': [2638], 'antibodies),': [2640], 'calculated': [2644], 'variety': [2647], 'looking': [2650], '(calculation': [2654], '[cPRA]/virtual': [2657], 'antibody/calculated': [2659], 'reaction': [2660], 'frequency': [2661, 2852], '[the': [2662], 'percentage': [2663], 'standardized': [2666], 'panel': [2667], '10,000': [2669], 'consecutive': [2670], 'HLA-typed': [2671], 'UK': [2672], 'donors': [2675, 2816], 'who': [2676, 2817, 2834, 3209], 'blood': [2678], 'group': [2679, 2791], 'identical': [2680], 'but': [2681, 2754, 3517], 'incompatible': [2683], 'alloantibody': [2686, 3926], 'profile': [2687], 'recipient]).3Schrezenmeier': [2692], 'that,': [2723], 'degree': [2728], 'homology': [2730], 'means': [2739, 3446], 'recognize': [2744, 2756], 'not': [2745, 3242], 'antigens': [2748, 2857], 'donor,': [2753], 'multiple': [2757], 'developed': [2764, 2839, 3748], 'HLA-B57': [2767], 'likelihood': [2772, 2950], 'recognizing': [2775], 'A2,': [2776], 'A23,': [2777], 'A24,': [2778], 'A68,': [2779], 'A69,': [2780], 'B58': [2782], '(that': [2783], 'same': [2788], 'cross': [2789], 'reactive': [2790], 'B57).': [2793], 'B57': [2798], 'present': [2800], '7%': [2802], 'according': [2806], 'cPRA': [2810, 3134, 3157, 3167], 'calculator,': [2811], 'proportion': [2813, 3112, 3146], 'may': [2818, 3510, 3776], '75%.': [2829], 'follows': [2831], 'lost': [2835], 'likely': [2843, 3287], 'broader': [2846], 'alloreactivity': [2848], 'than': [2849], 'mere': [2851], 'driven': [2860], '(Figure': [2863, 3316], '1).': [2864], 'study35Kosmoliaptsis': [2867], 'V.': [2868, 4004], 'Gjorgjimajkoska': [2869], 'Sharples': [2871], 'L.D.': [2872], 'al.Impact': [2874, 3362], 'individual': [2879], '-B,': [2881], '-C,': [2882], '-DR,': [2883], '-DQ': [2885], 'HLA-specific': [2891], 'listed': [2895], 'repeat': [2897, 3076, 3181], 'transplantation.Kidney': [2899, 3784], '2014;': [2901, 3380], '86:': [2902], '1039-1048Abstract': [2903], '(42)': [2911], 'increases': [2927], 'incrementally': [2928], 'This': [2942], 'profound': [2946], 'finding': [2952], 'second,': [2954], 'antibody-compatible,': [2955], 'donor.3Schrezenmeier': [2957], 'ScholarAccording': [2982], 'OPTN': [2984, 3203], 'approximately': [2986], '12%': [2987], '2020': [2993, 3426], 'awaiting': [2995, 3034, 3046, 3069, 3075, 3102, 3120, 3129, 3152, 3180, 3239, 3340], '9.8%': [2998], 'these': [3000, 3247, 3283, 3758], 'receiving': [3002, 3038, 3512], 'transplant.': [3006], 'frequencies': [3008], 'Eurotransplant,': [3012], '17%': [3014], 'retransplant': [3015, 3153, 3240], 'candidates': [3016, 3033], 'proceeding': [3022], 'transplantation;': [3024], 'Kingdom,': [3029], '22%': [3031], 'retransplantation': [3035, 3051, 3341], '16%': [3037], 'retransplantation.': [3039], 'primary': [3047, 3070, 3928], 'Figure': [3055, 3061, 3255, 3476, 3567], '2a': [3056], '(OPTN': [3057], 'data)': [3058], 'Supplementary': [3060], 'S1': [3062], '(UK': [3063], 'data).Figure': [3064], '2(a)': [3065], 'Comparison': [3066], 'States;': [3083], 'obtained': [3085, 3199], '(OPTN)': [3093], '2021.': [3096, 3206], 'Although': [3097, 3232], '0%': [3106], 'calculation': [3107, 3562], '(cPRA),': [3110], 'decreases': [3113], 'down': [3114], '27%': [3117], 'retransplant.': [3121], 'Conversely,': [3122], '2%': [3123], '4%': [3125], '98%': [3136, 3159], '100%': [3138], '80%': [3140, 3169], '97%,': [3142, 3171], 'whereas': [3144], 'grows': [3147], '31%': [3149], 'exhibiting': [3155], '100%;': [3161], '18%': [3164], 'total': [3174], 'almost': [3176], 'transplantation.': [3182, 3231], '(b)': [3183], 'peril': [3185], 'transplant:': [3191], 'comparing': [3192], 'Data': [3197, 3424], 'third': [3217], 'transplants,': [3218], 'prone': [3221], 'overall': [3234, 3392], 'high,': [3243], '39%': [3245], 'exhibit': [3249], 'cPRAs': [3250], '≥98%.View': [3252], 'Large': [3253, 3565], 'Image': [3254, 3566], 'ViewerDownload': [3256, 3568], 'Hi-res': [3257, 3569], 'image': [3258, 3570], 'Download': [3259, 3571], '(PPT)It': [3260], 'emphasize': [3264], 'perils': [3267], 'worse': [3275], 'young-adult': [3280], 'population': [3281], 'require': [3289], '>1': [3290], 'lifetime.': [3295], 'young': [3297, 3376], 'disproportionally': [3300], 'affected': [3301], 'pool': [3308], 'subjected': [3311], 'waiting': [3314, 3444], '2b).': [3317], '20%': [3328], 'children': [3332], 'failed': [3335, 3746], 'would': [3338], '>10': [3343], 'depending': [3345], 'level': [3348], 'donor.36Foster': [3355], 'Dahhou': [3357], 'Zhang': [3359], 'lifetime': [3371], 'function': [3374], 'recipients.Am': [3377], '14:': [3381], '876-885Crossref': [3382], '(35)': [3385], 'ScholarAt': [3387], 'societal': [3389], 'level,': [3390], 'taxpayer': [3397], 'programs': [3402], 'one': [3404], 'largest': [3407], 'costs': [3408], 'Centers': [3411], 'Medicare': [3413], '&': [3414], 'Medicaid': [3415], 'Services,': [3416], '~$50': [3418], 'billion': [3419], '(US': [3422], 'Annual': [3427], 'Report:': [3428], 'epidemiology': [3429], 'disease': [3432], 'States).': [3436], 'Finally,': [3437], 'list': [3445], '"competing"': [3449], 'resource': [3453], 'organs.': [3457], 'Taken': [3458], 'together,': [3459], 'becomes': [3461], 'apparent': [3462], 'multifaceted,': [3472], 'underpinning': [3478], 'research': [3483], 'effective': [3487], 'public': [3488], 'policy': [3489], 'area.Figure': [3492], '3The': [3493], 'vicious': [3494], 'cycle': [3495], '(ABMR).': [3506], 'Ignoring': [3507], 'expedite': [3511], 'puts': [3519], '(DSA),': [3531], 'episodes': [3532], 'ABMR,': [3534, 3875], 'intensified': [3538], 'prolonged': [3546], 'society': [3558], 'listed.': [3560], 'cPRA,': [3561], 'antibody.View': [3564], '(PPT)Impact': [3572], 'outcomesAlthough': [3580], 'HLA-DSAs': [3584], 'outcome,': [3593], 'now': [3595], 'vast': [3599], 'majority': [3600], 'target': [3605], 'molecules.24Wiebe': [3609], 'breakthrough': [3641], 'came': [3648], 'single-antigen': [3655], 'bead': [3656], 'assay': [3657], 'routine': [3659], 'testing': [3660, 3722], 'Iniotaki-Theodoraki': [3662], 'al.37Iniotaki-Theodoraki': [3664], 'A.G.': [3665], 'Trigas': [3668], 'al.Humoral': [3671], 'immune': [3672], 'reactivity': [3673], '(HLA)-DQ': [3678], 'molecules': [3680], 'early': [3683, 3705], 'posttransplantation': [3684], 'period.Transplantation.': [3685], '75:': [3687], '1601-1603Crossref': [3688], 'report': [3699], 'incidence': [3701, 3885], 'post-transplant': [3706], 'allografts.': [3711], 'Ozawa': [3712, 3943], 'al.38Ozawa': [3714], 'Rebellato': [3716, 3914, 3941], 'L.M.': [3717, 3915, 3942], 'al.Longitudinal': [3721], '266': [3724], 'MICA': [3731], 'antibodies:': [3732], 'Greenville': [3733], 'experience.Clin': [3734], 'Transpl.': [3735, 3995], '2006;': [3736], ':': [3737, 3997], '265-290PubMed': [3738], 'showed': [3741, 3805], 'before': [3752], 'directed': [3761], 'HLA-DQ.': [3763], 'DeVos': [3764], 'al.39DeVos': [3766], 'Gaber': [3768], 'A.O.': [3769], 'Knight': [3770], 'al.Donor-specific': [3773], 'contribute': [3777], 'poor': [3779], '82:': [3787], '598-604Abstract': [3788], '(130)': [3796], 'prospectively': [3799], 'monitored': [3800], '77%': [3807], 'targeted': [3814], 'exhibited': [3818], 'inferior': [3819], 'Willicombe': [3822], 'al.40Willicombe': [3824], 'Brookes': [3826], 'P.': [3827], 'Sergeant': [3828], 'al.De': [3831], 'glomerulopathy.Transplantation.': [3847], '94:': [3849], '172-177Crossref': [3850], '(175)': [3853], '54%': [3858], 'glomerulopathy,': [3877], 'loss.': [3880], 'findings,': [3882], 'organs,': [3898], 'well': [3900], 'loss,': [3909], 'reported.41Everly': [3912], 'M.J.': [3913], 'Haisch': [3916], 'C.E.': [3917], 'al.Incidence': [3919], 'allografts.Transplantation.': [3930], '95:': [3932, 3963], '410-417Crossref': [3933], '(284)': [3936], '42Freitas': [3939], 'M.C.': [3940], 'immunoglobulin-G': [3949], 'subclasses': [3950], 'C1q': [3952], 'outcomes.Transplantation.': [3961], '1113-1119Crossref': [3964], '(138)': [3967], '43Ticehurst': [3970], 'E.H.': [3971], 'Molina': [3972], 'M.R.': [3973], 'Frank': [3974], 'heart': [3980], 'patients:': [3982], 'follow': [3984], 'donor-directed': [3992], 'anti-DQ': [3993], 'antibodies.Clin': [3994], '409-414PubMed': [3998], '44Irving': [4001], 'C.A.': [4002], 'Carter': [4003], 'Gennery': [4005], 'A.R.': [4006], 'persistent': [4010], 'transient': [4012], 'cardiac': [4021], 'transplantation.J': [4022], 'Heart': [4023], 'Lung': [4024], '1310-1317Abstract': [4028], '(28)': [4036], '45Lobo': [4039], 'Aris': [4041], 'R.M.': [4042], 'Schmitz': [4043], 'Neuringer': [4045], 'I.P.': [4046], 'Donor-specific': [4047], 'acute': [4054], 'cellular': [4055], 'bronchiolitis': [4057], 'obliterans': [4058], 'syndrome,': [4059], 'cys': [4061]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3179084811', 'counts_by_year': [{'year': 2024, 'cited_by_count': 16}, {'year': 2023, 'cited_by_count': 24}, {'year': 2022, 'cited_by_count': 13}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-12-31T10:37:01.311808', 'created_date': '2021-07-19'}