Publication Information

{'id': 'https://openalex.org/W3176608394', 'doi': 'https://doi.org/10.1128/aac.00586-21', 'title': 'Properties of Plasmodium falciparum with a Deleted Apicoplast DNA Gyrase', 'display_name': 'Properties of Plasmodium falciparum with a Deleted Apicoplast DNA Gyrase', 'publication_year': 2021, 'publication_date': '2021-06-21', 'ids': {'openalex': 'https://openalex.org/W3176608394', 'doi': 'https://doi.org/10.1128/aac.00586-21', 'mag': '3176608394', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34152814', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8370227'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.00586-21', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://doi.org/10.1128/aac.00586-21', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5075567440', 'display_name': 'S N Tan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'SooNee Tan', 'raw_affiliation_strings': ['Department of Chemistry, University of Washington, Seattle, Washington, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, University of Washington, Seattle, Washington, USA', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035127609', 'display_name': 'Devaraja G. Mudeppa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Devaraja G. Mudeppa', 'raw_affiliation_strings': ['Department of Chemistry, University of Washington, Seattle, Washington, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, University of Washington, Seattle, Washington, USA', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085390052', 'display_name': 'Sreekanth Kokkonda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sreekanth Kokkonda', 'raw_affiliation_strings': ['Department of Chemistry, University of Washington, Seattle, Washington, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, University of Washington, Seattle, Washington, USA', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075997576', 'display_name': 'John White', 'orcid': 'https://orcid.org/0000-0001-7895-4443'}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John White', 'raw_affiliation_strings': ['Department of Chemistry, University of Washington, Seattle, Washington, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, University of Washington, Seattle, Washington, USA', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027135408', 'display_name': 'Rapatbhorn Patrapuvich', 'orcid': 'https://orcid.org/0000-0001-8214-5710'}, 'institutions': [{'id': 'https://openalex.org/I4210126604', 'display_name': 'Mahidol Oxford Tropical Medicine Research Unit', 'ror': 'https://ror.org/03fs9z545', 'country_code': 'TH', 'type': 'facility', 'lineage': ['https://openalex.org/I25399158', 'https://openalex.org/I40120149', 'https://openalex.org/I4210126604', 'https://openalex.org/I87048295']}, {'id': 'https://openalex.org/I25399158', 'display_name': 'Mahidol University', 'ror': 'https://ror.org/01znkr924', 'country_code': 'TH', 'type': 'education', 'lineage': ['https://openalex.org/I25399158']}, {'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['TH', 'US'], 'is_corresponding': False, 'raw_author_name': 'Rapatbhorn Patrapuvich', 'raw_affiliation_strings': ['Department of Chemistry, University of Washington, Seattle, Washington, USA', 'Drug Research Unit for Malaria, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand'], 'affiliations': [{'raw_affiliation_string': 'Drug Research Unit for Malaria, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand', 'institution_ids': ['https://openalex.org/I4210126604', 'https://openalex.org/I25399158']}, {'raw_affiliation_string': 'Department of Chemistry, University of Washington, Seattle, Washington, USA', 'institution_ids': ['https://openalex.org/I201448701']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5025549234', 'display_name': 'Pradipsinh K. Rathod', 'orcid': 'https://orcid.org/0000-0001-7394-1360'}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Pradipsinh K. Rathod', 'raw_affiliation_strings': ['Department of Chemistry, University of Washington, Seattle, Washington, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, University of Washington, Seattle, Washington, USA', 'institution_ids': ['https://openalex.org/I201448701']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5025549234'], 'corresponding_institution_ids': ['https://openalex.org/I201448701'], 'apc_list': None, 'apc_paid': None, 'fwci': 3.177, 'has_fulltext': False, 'cited_by_count': 15, 'citation_normalized_percentile': {'value': 0.999976, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '65', 'issue': '9', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.994, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11845', 'display_name': 'Cancer therapeutics and mechanisms', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/apicoplast', 'display_name': 'Apicoplast', 'score': 0.99774146}, {'id': 'https://openalex.org/keywords/plasmodium', 'display_name': 'Plasmodium (life cycle)', 'score': 0.4801197}, {'id': 'https://openalex.org/keywords/organelle', 'display_name': 'Organelle', 'score': 0.43624368}], 'concepts': [{'id': 'https://openalex.org/C2775855988', 'wikidata': 'https://www.wikidata.org/wiki/Q1825478', 'display_name': 'Apicoplast', 'level': 5, 'score': 0.99774146}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.823948}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.7763344}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.76666546}, {'id': 'https://openalex.org/C93829228', 'wikidata': 'https://www.wikidata.org/wiki/Q165963', 'display_name': 'Plastid', 'level': 4, 'score': 0.7550795}, {'id': 'https://openalex.org/C167125095', 'wikidata': 'https://www.wikidata.org/wiki/Q70551687', 'display_name': 'DNA gyrase', 'level': 4, 'score': 0.62974215}, {'id': 'https://openalex.org/C24586158', 'wikidata': 'https://www.wikidata.org/wiki/Q27075', 'display_name': 'Mitochondrial DNA', 'level': 3, 'score': 0.61189526}, {'id': 'https://openalex.org/C2781023229', 'wikidata': 'https://www.wikidata.org/wiki/Q193030', 'display_name': 'Apicomplexa', 'level': 4, 'score': 0.5916076}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.5726245}, {'id': 'https://openalex.org/C2778675580', 'wikidata': 'https://www.wikidata.org/wiki/Q614956', 'display_name': 'Plasmodium (life cycle)', 'level': 3, 'score': 0.4801197}, {'id': 'https://openalex.org/C168240541', 'wikidata': 'https://www.wikidata.org/wiki/Q45948', 'display_name': 'Organelle', 'level': 2, 'score': 0.43624368}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.4046375}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.3886065}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.27100503}, {'id': 'https://openalex.org/C71928629', 'wikidata': 'https://www.wikidata.org/wiki/Q804206', 'display_name': 'Parasite hosting', 'level': 2, 'score': 0.20515823}, {'id': 'https://openalex.org/C69305403', 'wikidata': 'https://www.wikidata.org/wiki/Q47263', 'display_name': 'Chloroplast', 'level': 3, 'score': 0.0980041}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.057824224}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D063546', 'descriptor_name': 'Apicoplasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D063546', 'descriptor_name': 'Apicoplasts', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D027081', 'descriptor_name': 'DNA Gyrase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D027081', 'descriptor_name': 'DNA Gyrase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015800', 'descriptor_name': 'Protozoan Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015800', 'descriptor_name': 'Protozoan Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.00586-21', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370227', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34152814', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/aac.00586-21', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.8}], 'grants': [{'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'U19 AI089688'}], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W107345780', 'https://openalex.org/W1617412318', 'https://openalex.org/W1749439186', 'https://openalex.org/W1919257374', 'https://openalex.org/W1969503178', 'https://openalex.org/W1971509443', 'https://openalex.org/W1977123265', 'https://openalex.org/W1982597069', 'https://openalex.org/W1987311633', 'https://openalex.org/W1990617810', 'https://openalex.org/W2005044534', 'https://openalex.org/W2007852671', 'https://openalex.org/W2012061580', 'https://openalex.org/W2019851585', 'https://openalex.org/W2024166317', 'https://openalex.org/W2027214692', 'https://openalex.org/W2029229088', 'https://openalex.org/W2030488581', 'https://openalex.org/W2034520962', 'https://openalex.org/W2049183597', 'https://openalex.org/W2055730063', 'https://openalex.org/W2068577449', 'https://openalex.org/W2074472791', 'https://openalex.org/W2074543807', 'https://openalex.org/W2080412532', 'https://openalex.org/W2085462579', 'https://openalex.org/W2085835962', 'https://openalex.org/W2101664493', 'https://openalex.org/W2110343132', 'https://openalex.org/W2119180969', 'https://openalex.org/W2134213012', 'https://openalex.org/W2137991952', 'https://openalex.org/W2138700717', 'https://openalex.org/W2143192331', 'https://openalex.org/W2155752689', 'https://openalex.org/W2161273888', 'https://openalex.org/W2169690281', 'https://openalex.org/W2171254101', 'https://openalex.org/W2239961991', 'https://openalex.org/W2312976018', 'https://openalex.org/W2344075384', 'https://openalex.org/W2412804509', 'https://openalex.org/W2767970508', 'https://openalex.org/W4236530034'], 'related_works': ['https://openalex.org/W4256246041', 'https://openalex.org/W3020621316', 'https://openalex.org/W2538215728', 'https://openalex.org/W2472737120', 'https://openalex.org/W2412157758', 'https://openalex.org/W2324327749', 'https://openalex.org/W2150561065', 'https://openalex.org/W2009850071', 'https://openalex.org/W1998121672', 'https://openalex.org/W1998059890'], 'abstract_inverted_index': {'Malaria': [0], 'parasites': [1], 'have': [2, 55], 'three': [3], 'genomes:': [4], 'a': [5, 8, 19, 36], 'nuclear': [6], 'genome,': [7, 10], 'mitochondrial': [9], 'and': [11, 25, 51], 'an': [12], 'apicoplast': [13, 17], 'genome.': [14], 'Since': [15], 'the': [16, 30], 'is': [18], 'plastid': [20], 'organelle': [21], 'of': [22, 38], 'prokaryotic': [23], 'origin': [24], 'has': [26], 'no': [27], 'counterpart': [28], 'in': [29], 'human': [31], 'host,': [32], 'it': [33], 'can': [34], 'be': [35], 'source': [37], 'novel': [39], 'targets': [40], 'for': [41], 'antimalarials.': [42], 'Plasmodium': [43], 'falciparum': [44], 'DNA': [45], 'gyrase': [46], '(': [47], 'Pf': [48], 'Gyr)': [49], 'A': [50], 'B': [52], 'subunits': [53], 'both': [54], 'apicoplast-targeting': [56], 'signals.': [57]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3176608394', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 1}], 'updated_date': '2024-12-19T22:10:29.890777', 'created_date': '2021-07-05'}