Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3170157013', 'doi': 'https://doi.org/10.3390/ijms22126381', 'title': 'Potential of Naturally Derived Compounds in Telomerase and Telomere Modulation in Skin Senescence and Aging', 'display_name': 'Potential of Naturally Derived Compounds in Telomerase and Telomere Modulation in Skin Senescence and Aging', 'publication_year': 2021, 'publication_date': '2021-06-15', 'ids': {'openalex': 'https://openalex.org/W3170157013', 'doi': 'https://doi.org/10.3390/ijms22126381', 'mag': '3170157013', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34203694', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8232155'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijms22126381', 'pdf_url': 'https://www.mdpi.com/1422-0067/22/12/6381/pdf?version=1623752634', 'source': {'id': 'https://openalex.org/S10623703', 'display_name': 'International Journal of Molecular Sciences', 'issn_l': '1422-0067', 'issn': ['1422-0067', '1661-6596'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/1422-0067/22/12/6381/pdf?version=1623752634', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5079251165', 'display_name': 'Barbara Jacczak', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I120230055', 'display_name': 'Poznan University of Medical Sciences', 'ror': 'https://ror.org/02zbb2597', 'country_code': 'PL', 'type': 'education', 'lineage': ['https://openalex.org/I120230055']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Barbara Jacczak', 'raw_affiliation_strings': ['Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznań, Poland'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznań, Poland', 'institution_ids': ['https://openalex.org/I120230055']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081463984', 'display_name': 'Błażej Rubiś', 'orcid': 'https://orcid.org/0000-0003-1730-0176'}, 'institutions': [{'id': 'https://openalex.org/I120230055', 'display_name': 'Poznan University of Medical Sciences', 'ror': 'https://ror.org/02zbb2597', 'country_code': 'PL', 'type': 'education', 'lineage': ['https://openalex.org/I120230055']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Błażej Rubiś', 'raw_affiliation_strings': ['Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznań, Poland'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznań, Poland', 'institution_ids': ['https://openalex.org/I120230055']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5018542932', 'display_name': 'Ewa Totoń', 'orcid': 'https://orcid.org/0000-0002-7602-1604'}, 'institutions': [{'id': 'https://openalex.org/I120230055', 'display_name': 'Poznan University of Medical Sciences', 'ror': 'https://ror.org/02zbb2597', 'country_code': 'PL', 'type': 'education', 'lineage': ['https://openalex.org/I120230055']}], 'countries': ['PL'], 'is_corresponding': True, 'raw_author_name': 'Ewa Totoń', 'raw_affiliation_strings': ['Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznań, Poland'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznań, Poland', 'institution_ids': ['https://openalex.org/I120230055']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5018542932'], 'corresponding_institution_ids': ['https://openalex.org/I120230055'], 'apc_list': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'apc_paid': {'value': 2300, 'currency': 'CHF', 'value_usd': 2490, 'provenance': 'doaj'}, 'fwci': 0.617, 'has_fulltext': False, 'cited_by_count': 18, 'citation_normalized_percentile': {'value': 0.446035, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '22', 'issue': '12', 'first_page': '6381', 'last_page': '6381'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10937', 'display_name': 'Cellular Senescence and Aging-Related Diseases', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10937', 'display_name': 'Cellular Senescence and Aging-Related Diseases', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11013', 'display_name': 'Mechanisms of Skin Aging and Photodamage', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2708', 'display_name': 'Dermatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10445', 'display_name': 'Role of Oxidative Stress in Health and Disease', 'score': 0.969, 'subfield': {'id': 'https://openalex.org/subfields/2704', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/senescence', 'display_name': 'Senescence', 'score': 0.75186026}, {'id': 'https://openalex.org/keywords/cellular-senescence', 'display_name': 'Cellular senescence', 'score': 0.6205482}, {'id': 'https://openalex.org/keywords/telomerase', 'display_name': 'Telomerase', 'score': 0.536671}, {'id': 'https://openalex.org/keywords/aging', 'display_name': 'Aging', 'score': 0.508125}], 'concepts': [{'id': 'https://openalex.org/C94581717', 'wikidata': 'https://www.wikidata.org/wiki/Q331839', 'display_name': 'Telomerase', 'level': 3, 'score': 0.98821497}, {'id': 'https://openalex.org/C177336024', 'wikidata': 'https://www.wikidata.org/wiki/Q14872779', 'display_name': 'Telomere', 'level': 3, 'score': 0.97601974}, {'id': 'https://openalex.org/C522857546', 'wikidata': 'https://www.wikidata.org/wiki/Q2070979', 'display_name': 'Senescence', 'level': 2, 'score': 0.75186026}, {'id': 'https://openalex.org/C2779523775', 'wikidata': 'https://www.wikidata.org/wiki/Q9075999', 'display_name': 'Cellular senescence', 'level': 4, 'score': 0.6205482}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5964917}, {'id': 'https://openalex.org/C125593758', 'wikidata': 'https://www.wikidata.org/wiki/Q15315135', 'display_name': 'Telomerase reverse transcriptase', 'level': 4, 'score': 0.55976456}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.49513116}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.3822142}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.343634}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.32177004}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.28038928}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.20465311}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.120607525}], 'mesh': [{'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001688', 'descriptor_name': 'Biological Products', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D019098', 'descriptor_name': 'Telomerase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016615', 'descriptor_name': 'Telomere', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001688', 'descriptor_name': 'Biological Products', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D019098', 'descriptor_name': 'Telomerase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016615', 'descriptor_name': 'Telomere', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijms22126381', 'pdf_url': 'https://www.mdpi.com/1422-0067/22/12/6381/pdf?version=1623752634', 'source': {'id': 'https://openalex.org/S10623703', 'display_name': 'International Journal of Molecular Sciences', 'issn_l': '1422-0067', 'issn': ['1422-0067', '1661-6596'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/24f1fb2a3456416397470f5bd174db40', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232155', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34203694', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/ijms22126381', 'pdf_url': 'https://www.mdpi.com/1422-0067/22/12/6381/pdf?version=1623752634', 'source': {'id': 'https://openalex.org/S10623703', 'display_name': 'International Journal of Molecular Sciences', 'issn_l': '1422-0067', 'issn': ['1422-0067', '1661-6596'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320322511', 'funder_display_name': 'Narodowe Centrum Nauki', 'award_id': '2016/21/B/NZ7/01079'}], 'datasets': [], 'versions': [], 'referenced_works_count': 198, 'referenced_works': ['https://openalex.org/W1171610272', 'https://openalex.org/W127362141', 'https://openalex.org/W1502298083', 'https://openalex.org/W1507371669', 'https://openalex.org/W1612842202', 'https://openalex.org/W1631191622', 'https://openalex.org/W1751954544', 'https://openalex.org/W176973267', 'https://openalex.org/W1783508367', 'https://openalex.org/W1803305660', 'https://openalex.org/W1824527491', 'https://openalex.org/W1892268352', 'https://openalex.org/W1908195810', 'https://openalex.org/W1910928745', 'https://openalex.org/W1952511673', 'https://openalex.org/W1955005729', 'https://openalex.org/W1964543951', 'https://openalex.org/W1966087162', 'https://openalex.org/W1970177659', 'https://openalex.org/W1970924670', 'https://openalex.org/W1973577066', 'https://openalex.org/W1974718218', 'https://openalex.org/W1976273464', 'https://openalex.org/W1978146096', 'https://openalex.org/W1978213280', 'https://openalex.org/W1978720331', 'https://openalex.org/W1979264673', 'https://openalex.org/W1979953806', 'https://openalex.org/W1981721889', 'https://openalex.org/W1983125814', 'https://openalex.org/W1984252723', 'https://openalex.org/W1984967097', 'https://openalex.org/W1987221116', 'https://openalex.org/W1988327952', 'https://openalex.org/W1991827974', 'https://openalex.org/W1992129110', 'https://openalex.org/W1993571663', 'https://openalex.org/W1994972521', 'https://openalex.org/W1998111191', 'https://openalex.org/W1998813237', 'https://openalex.org/W2004314923', 'https://openalex.org/W2005453919', 'https://openalex.org/W2006315712', 'https://openalex.org/W2009668465', 'https://openalex.org/W2012565034', 'https://openalex.org/W2015012480', 'https://openalex.org/W2015629056', 'https://openalex.org/W2018182154', 'https://openalex.org/W2019276374', 'https://openalex.org/W2020450893', 'https://openalex.org/W2025894464', 'https://openalex.org/W2026582785', 'https://openalex.org/W2027534174', 'https://openalex.org/W2027598856', 'https://openalex.org/W2030812402', 'https://openalex.org/W2032168846', 'https://openalex.org/W2033861401', 'https://openalex.org/W2034535394', 'https://openalex.org/W2036710751', 'https://openalex.org/W2037480531', 'https://openalex.org/W2042095358', 'https://openalex.org/W2043204829', 'https://openalex.org/W2043950060', 'https://openalex.org/W2045033598', 'https://openalex.org/W2047222159', 'https://openalex.org/W2047311850', 'https://openalex.org/W2047469560', 'https://openalex.org/W2049903344', 'https://openalex.org/W2050166933', 'https://openalex.org/W2050723355', 'https://openalex.org/W2055000500', 'https://openalex.org/W2060736036', 'https://openalex.org/W2063116304', 'https://openalex.org/W2064248337', 'https://openalex.org/W2064726545', 'https://openalex.org/W2067703401', 'https://openalex.org/W2068560722', 'https://openalex.org/W2069513973', 'https://openalex.org/W2072908461', 'https://openalex.org/W2074991976', 'https://openalex.org/W2077084571', 'https://openalex.org/W2078691986', 'https://openalex.org/W2082402714', 'https://openalex.org/W2085786821', 'https://openalex.org/W2086316954', 'https://openalex.org/W2087003474', 'https://openalex.org/W2087206540', 'https://openalex.org/W2096903993', 'https://openalex.org/W2100021953', 'https://openalex.org/W2100259806', 'https://openalex.org/W2102802702', 'https://openalex.org/W2106876162', 'https://openalex.org/W2110419228', 'https://openalex.org/W2111342463', 'https://openalex.org/W2112049232', 'https://openalex.org/W2112126701', 'https://openalex.org/W2116362631', 'https://openalex.org/W2116437342', 'https://openalex.org/W2117889420', 'https://openalex.org/W2122116064', 'https://openalex.org/W2122397972', 'https://openalex.org/W2124098526', 'https://openalex.org/W2125121177', 'https://openalex.org/W2126525177', 'https://openalex.org/W2128104236', 'https://openalex.org/W2128378945', 'https://openalex.org/W2129896687', 'https://openalex.org/W2130458932', 'https://openalex.org/W2134718821', 'https://openalex.org/W2137600062', 'https://openalex.org/W2138936179', 'https://openalex.org/W2139808613', 'https://openalex.org/W2141310245', 'https://openalex.org/W2141440036', 'https://openalex.org/W2141976681', 'https://openalex.org/W2142021077', 'https://openalex.org/W2143471290', 'https://openalex.org/W2149045518', 'https://openalex.org/W2149644711', 'https://openalex.org/W2150228504', 'https://openalex.org/W2151558911', 'https://openalex.org/W2151850423', 'https://openalex.org/W2153282479', 'https://openalex.org/W2154938844', 'https://openalex.org/W2155238230', 'https://openalex.org/W2159524064', 'https://openalex.org/W2160179669', 'https://openalex.org/W2160576359', 'https://openalex.org/W2162043650', 'https://openalex.org/W2167264988', 'https://openalex.org/W2168798429', 'https://openalex.org/W2173698021', 'https://openalex.org/W2193792657', 'https://openalex.org/W2206099919', 'https://openalex.org/W2312920778', 'https://openalex.org/W2326591292', 'https://openalex.org/W2336163076', 'https://openalex.org/W2336178818', 'https://openalex.org/W2338208607', 'https://openalex.org/W2355142079', 'https://openalex.org/W2361168337', 'https://openalex.org/W2361253583', 'https://openalex.org/W2368123263', 'https://openalex.org/W2375462945', 'https://openalex.org/W2388865542', 'https://openalex.org/W2399143381', 'https://openalex.org/W2476542314', 'https://openalex.org/W2502603894', 'https://openalex.org/W2516998924', 'https://openalex.org/W2517194717', 'https://openalex.org/W2549447033', 'https://openalex.org/W2564905261', 'https://openalex.org/W2566877989', 'https://openalex.org/W2573540928', 'https://openalex.org/W2606918260', 'https://openalex.org/W2607214955', 'https://openalex.org/W2615683714', 'https://openalex.org/W2615758281', 'https://openalex.org/W2620914886', 'https://openalex.org/W2621706101', 'https://openalex.org/W2734671955', 'https://openalex.org/W2753350647', 'https://openalex.org/W2767482921', 'https://openalex.org/W2768033029', 'https://openalex.org/W2771646433', 'https://openalex.org/W2784360276', 'https://openalex.org/W2789947828', 'https://openalex.org/W2793030121', 'https://openalex.org/W2796888593', 'https://openalex.org/W2800438504', 'https://openalex.org/W2810861436', 'https://openalex.org/W2891429343', 'https://openalex.org/W2892224724', 'https://openalex.org/W2902257857', 'https://openalex.org/W2905499092', 'https://openalex.org/W2908896570', 'https://openalex.org/W2910427173', 'https://openalex.org/W2914968800', 'https://openalex.org/W2941968533', 'https://openalex.org/W2946740283', 'https://openalex.org/W2947633790', 'https://openalex.org/W2951872997', 'https://openalex.org/W2953895644', 'https://openalex.org/W2962043899', 'https://openalex.org/W2969400161', 'https://openalex.org/W2981646639', 'https://openalex.org/W2995359774', 'https://openalex.org/W2995774252', 'https://openalex.org/W3001456491', 'https://openalex.org/W3010215457', 'https://openalex.org/W3013602850', 'https://openalex.org/W3038474333', 'https://openalex.org/W3044938674', 'https://openalex.org/W3080980637', 'https://openalex.org/W3093232305', 'https://openalex.org/W4247218755', 'https://openalex.org/W4252349553', 'https://openalex.org/W97711432'], 'related_works': ['https://openalex.org/W60632522', 'https://openalex.org/W3170157013', 'https://openalex.org/W2417511905', 'https://openalex.org/W2371502216', 'https://openalex.org/W2356050715', 'https://openalex.org/W2352675258', 'https://openalex.org/W2103156000', 'https://openalex.org/W2073119209', 'https://openalex.org/W2059190566', 'https://openalex.org/W1946284234'], 'abstract_inverted_index': {'Proper': [0], 'functioning': [1], 'of': [2, 35, 49, 53, 69, 125, 138], 'cells-their': [3], 'ability': [4], 'to': [5, 18, 37, 106, 121, 141], 'divide,': [6], 'differentiate,': [7], 'and': [8, 30, 52, 55, 74, 108, 127, 144, 147, 151], 'regenerate-is': [9], 'dictated': [10], 'by': [11, 62], 'genomic': [12], 'stability.': [13], 'The': [14], 'main': [15], 'factors': [16], 'contributing': [17], 'this': [19], 'stability': [20], 'are': [21, 60], 'the': [22, 47, 66, 135], 'telomeric': [23], 'ends': [24], 'that': [25, 77], 'cap': [26], 'chromosomes.': [27], 'Telomere': [28], 'biology': [29, 146], 'telomerase': [31, 70, 75, 109, 143], 'activity': [32, 76], 'have': [33], 'been': [34], 'interest': [36], 'scientists': [38], 'in': [39, 92, 97], 'various': [40], 'medical': [41], 'science': [42], 'fields': [43], 'for': [44], 'years,': [45], 'including': [46], 'study': [48], 'both': [50], 'cancer': [51], 'senescence': [54, 150], 'aging.': [56, 153], 'All': [57], 'these': [58], 'processes': [59], 'accompanied': [61], 'telomere-length': [63], 'modulation.': [64], 'Maintaining': [65], 'key': [67], 'levels': [68], 'component': [71], '(hTERT)': [72], 'expression': [73], 'provide': [78], 'optimal': [79], 'telomere': [80, 107, 145], 'length': [81], 'as': [82, 84], 'well': [83], 'some': [85], 'nontelomeric': [86], 'functions': [87], 'represents': [88], 'a': [89], 'promising': [90], 'step': [91], 'advanced': [93], 'anti-aging': [94], 'strategies,': [95], 'especially': [96], 'dermocosmetics.': [98], 'Some': [99], 'known': [100], 'naturally': [101], 'derived': [102], 'compounds': [103, 140], 'contribute': [104], 'significantly': [105], 'metabolism.': [110], 'However,': [111], 'before': [112], 'they': [113], 'can': [114], 'be': [115], 'safely': [116], 'used,': [117], 'it': [118], 'is': [119], 'necessary': [120], 'assess': [122], 'their': [123], 'mechanisms': [124], 'action': [126], 'potential': [128, 137], 'side': [129], 'effects.': [130], 'This': [131], 'paper': [132], 'focuses': [133], 'on': [134], 'metabolic': [136], 'natural': [139], 'modulate': [142], 'thus': [148], 'prevent': [149], 'skin': [152]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3170157013', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 7}], 'updated_date': '2024-09-13T15:56:53.788639', 'created_date': '2021-06-22'}